Bus from St. Louis, MO to Indianapolis from $28

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Compare all timetables for the bus from St. Louis, MO to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Indianapolis from various bus operators like Greyhound US for the next days.
today
tomorrow
$35
Tuesday
$28
Wednesday
$28
Thursday
$35
Friday
Saturday
$37

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 4h 25m 2:00 AM St. Louis, MO Gateway Station 7:25 AM Indianapolis Central Bus Station  Economy $35
Greyhound US 4h 45m 8:45 AM St. Louis, MO Gateway Station 2:30 PM Indianapolis Central Bus Station  Economy $35
Greyhound US 4h 25m 1:55 PM St. Louis, MO Gateway Station 7:20 PM Indianapolis Central Bus Station  Economy $35

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 4h 25m 2:00 AM St. Louis, MO Gateway Station 7:25 AM Indianapolis Central Bus Station  Economy $28
Greyhound US 4h 45m 8:45 AM St. Louis, MO Gateway Station 2:30 PM Indianapolis Central Bus Station  Economy $28
Greyhound US 4h 25m 1:55 PM St. Louis, MO Gateway Station 7:20 PM Indianapolis Central Bus Station  Economy $28

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 4h 25m 2:00 AM St. Louis, MO Gateway Station 7:25 AM Indianapolis Central Bus Station  Economy $28
Greyhound US 4h 45m 8:45 AM St. Louis, MO Gateway Station 2:30 PM Indianapolis Central Bus Station  Economy $28
Greyhound US 4h 25m 1:55 PM St. Louis, MO Gateway Station 7:20 PM Indianapolis Central Bus Station  Economy $29

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 4h 25m 2:00 AM St. Louis, MO Gateway Station 7:25 AM Indianapolis Central Bus Station  Economy $35
Greyhound US 4h 45m 8:45 AM St. Louis, MO Gateway Station 2:30 PM Indianapolis Central Bus Station  Economy $35
Greyhound US 4h 25m 1:55 PM St. Louis, MO Gateway Station 7:20 PM Indianapolis Central Bus Station  Economy $38

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 4h 25m 2:00 AM St. Louis, MO Gateway Station 7:25 AM Indianapolis Central Bus Station  Economy $37
Greyhound US 4h 45m 8:45 AM St. Louis, MO Gateway Station 2:30 PM Indianapolis Central Bus Station  Economy $38
Greyhound US 4h 25m 1:55 PM St. Louis, MO Gateway Station 7:20 PM Indianapolis Central Bus Station  Economy $39

Frequency of bus connections between St. Louis, MO and Indianapolis

See here how frequent the connections between St. Louis, MO and Indianapolis are, during different times and days of the week.
Monday is the busiest day, with more than 3 daily buses from St. Louis, MO to Indianapolis. Monday has instead the fewest connections, with only 3 daily coaches between St. Louis, MO and Indianapolis.
The busiest time of the day is the Morning, with 5 buses from St. Louis, MO to Indianapolis, while Morning sees the fewest connections between St. Louis, MO and Indianapolis, with 5 offers.

Test cheapest views

The cheapest bus for the 7/28/2026 costs just $28, from Greyhound US

Facts about the bus from St. Louis, MO to Indianapolis

Compare all providers like Greyhound US that travel 3 times every day by bus from St. Louis, MO to Indianapolis in one click! Book your bus ticket from St. Louis, MO to Indianapolis starting from $28!

Cheapest Bus $28
Fastest Bus 5h 25m
Earliest Bus 2:00 AM
Latest Bus 1:55 PM
Daily Bus Routes 3 Ø
Distance 230.8 miles
Bus Companies Greyhound US

Cheapest bus connections from St. Louis, MO to Indianapolis

Every day, 3 buses from 1 bus companies leave St. Louis, MO for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/26
Monday 07/27
$35
Tuesday 07/28
$28
Wednesday 07/29
$28
Thursday 07/30
$35
Friday 07/31
Saturday 08/01
$37
Sunday 08/02
$37
Monday 08/03
Tuesday 08/04
$32
Wednesday 08/05
Thursday 08/06
Friday 08/07
Saturday 08/08
Sunday 08/09
Monday 08/10
$35
Tuesday 08/11
Wednesday 08/12
$36
Thursday 08/13
Friday 08/14
Saturday 08/15
Sunday 08/16
$33
Monday 08/17
Tuesday 08/18
$33
Wednesday 08/19
Thursday 08/20
Friday 08/21
Saturday 08/22

The cheapest time to travel from St. Louis, MO to Indianapolis

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Indianapolis, for the next 30 days.
With a price starting from $28, Tuesday is the cheapest day for a bus from St. Louis, MO to Indianapolis. Saturday instead is the most expensive day with prices starting from $37.
Morning is the cheapest day time for bus tickets from St. Louis, MO to Indianapolis, with $28. Morning is the most expensive time of the day with prices starting from $28.

How to save money travelling from St. Louis, MO to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Indianapolis are also emptier.

All bus stations and stops in St. Louis, MO and Indianapolis

In the map below, you can see where to find all bus stations in St. Louis, MO and Indianapolis.

Service and Comfort on the bus from St. Louis, MO to Indianapolis

Want to know which seat classes are available on the buses from St. Louis, MO to Indianapolis? Or which bus companies serve the route St. Louis, MO to Indianapolis? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Indianapolis bus

How much does a St. Louis, MO Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $28 and takes 5h 25m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Indianapolis?

This route is offered by 1 companies with a range of ticket prices between $28 and $39. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from St. Louis, MO to Indianapolis each day?

Every day, the St. Louis, MO to Indianapolis bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Indianapolis take?

The fastest bus from St. Louis, MO to Indianapolis is offered by Greyhound US and takes 5h 25m. Bus tickets for this connection cost $35. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Indianapolis?

The earliest bus arriving in Indianapolis from St. Louis, MO starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Indianapolis?

The latest bus trip departing from St. Louis, MO for Indianapolis starts at 1:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Indianapolis route?

When traveling by bus from St. Louis, MO to Indianapolis, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Indianapolis?

You can check all the direct connections between St. Louis, MO and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the St. Louis, MO to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Indianapolis on your planned travel date.

Available seat classes which are offered on the bus route St. Louis, MO to Indianapolis

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Indianapolis

Here’s an overview of the most popular bus routes to St. Louis, MO and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to St. Louis, MO and to Indianapolis
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