Bus St. Louis, MO to Indianapolis: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Indianapolis from various bus operators like Greyhound US for the next days.

today

tomorrow

$29

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Saturday

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Tuesday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	4h 45m	8:45 AM	St. Louis, MO	Gateway Station	2:30 PM	Indianapolis	Central Bus Station	Economy	$29	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 9/10/2026 8:45:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/10/2026 2:30:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 4h 45m
Greyhound US	4h 25m	2:00 AM	St. Louis, MO	Gateway Station	7:25 AM	Indianapolis	Central Bus Station	Economy	$32	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 9/10/2026 2:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/10/2026 7:25:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 4h 25m
Greyhound US	4h 25m	2:05 PM	St. Louis, MO	Gateway Station	7:30 PM	Indianapolis	Central Bus Station	Economy	$33	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 9/10/2026 2:05:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/10/2026 7:30:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 4h 25m

Test cheapest views

The cheapest bus for the 9/10/2026 costs just $29, from Greyhound US

Facts about the bus from St. Louis, MO to Indianapolis

Compare all providers like Greyhound US that travel 6 times every day by bus from St. Louis, MO to Indianapolis in one click! Book your bus ticket from St. Louis, MO to Indianapolis starting from $29!

Cheapest Bus	$29
Fastest Bus	5h 25m
Earliest Bus	2:00 AM
Latest Bus	2:05 PM
Daily Bus Routes	6 Ø
Distance	230.8 miles
Bus Companies	Greyhound US

Cheapest bus connections from St. Louis, MO to Indianapolis

Every day, 6 buses from 1 bus companies leave St. Louis, MO for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/09/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

Wednesday 09/09

Thursday 09/10

$29

Friday 09/11

Saturday 09/12

Sunday 09/13

Monday 09/14

Tuesday 09/15

Wednesday 09/16

Thursday 09/17

Friday 09/18

Saturday 09/19

Sunday 09/20

Monday 09/21

Tuesday 09/22

Wednesday 09/23

Thursday 09/24

Friday 09/25

Saturday 09/26

Sunday 09/27

Monday 09/28

Tuesday 09/29

Wednesday 09/30

Thursday 10/01

Friday 10/02

Saturday 10/03

How to save money travelling from St. Louis, MO to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Indianapolis are also emptier.

All bus stations and stops in St. Louis, MO and Indianapolis

In the map below, you can see where to find all bus stations in St. Louis, MO and Indianapolis.

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Central Bus Station

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

Service and Comfort on the bus from St. Louis, MO to Indianapolis

Want to know which seat classes are available on the buses from St. Louis, MO to Indianapolis? Or which bus companies serve the route St. Louis, MO to Indianapolis? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Indianapolis bus

How much does a St. Louis, MO Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $29 and takes 5h 45m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Indianapolis?

This route is offered by 1 companies with a range of ticket prices between $29 and $35. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from St. Louis, MO to Indianapolis each day?

Every day, the St. Louis, MO to Indianapolis bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Indianapolis take?

The fastest bus from St. Louis, MO to Indianapolis is offered by Greyhound US and takes 5h 25m. Bus tickets for this connection cost $33. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Indianapolis?

The earliest bus arriving in Indianapolis from St. Louis, MO starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Indianapolis?

The latest bus trip departing from St. Louis, MO for Indianapolis starts at 2:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Indianapolis route?

When traveling by bus from St. Louis, MO to Indianapolis, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Indianapolis?

You can check all the direct connections between St. Louis, MO and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the St. Louis, MO to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Indianapolis on your planned travel date.

Available seat classes which are offered on the bus route St. Louis, MO to Indianapolis

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Indianapolis

Here’s an overview of the most popular bus routes to St. Louis, MO and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!