Bus Jacksonville, FL to Indianapolis: Compare prices and save money

Compare all timetables for the bus from Jacksonville, FL to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from Jacksonville, FL to Indianapolis from various bus operators like FlixBus or Greyhound US for the next days.

today

$105

tomorrow

$112

Monday

Tuesday

Wednesday

Thursday

$99

Friday

$102

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 20m	9:25 PM	Jacksonville, FL	Downtown Bus Stop	9:45 PM	Indianapolis	Downtown Transit Center	Economy	$105	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/25/2026 9:25:00 PM to Downtown Transit Center, Indianapolis (USA) arriving at 7/26/2026 9:45:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 24h 20m
FlixBus	19h 40m	4:30 PM	Jacksonville, FL	Downtown Bus Stop	12:10 PM	Indianapolis	Central Bus Station	Economy	$106	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/25/2026 4:30:00 PM to Central Bus Station, Indianapolis (USA) arriving at 7/26/2026 12:10:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 19h 40m
FlixBus	19h 20m	9:25 PM	Jacksonville, FL	Downtown Bus Stop	4:45 PM	Indianapolis	Central Bus Station	Economy	$106	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/25/2026 9:25:00 PM to Central Bus Station, Indianapolis (USA) arriving at 7/26/2026 4:45:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 19h 20m
FlixBus	32h 45m	11:15 PM	Jacksonville, FL	Downtown Bus Stop	8:00 AM	Indianapolis	Downtown Transit Center	Economy	$112	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/25/2026 11:15:00 PM to Downtown Transit Center, Indianapolis (USA) arriving at 7/27/2026 8:00:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 32h 45m
FlixBus	29h 40m	11:15 PM	Jacksonville, FL	Downtown Bus Stop	4:55 AM	Indianapolis	Central Bus Station	Economy	$125	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/25/2026 11:15:00 PM to Central Bus Station, Indianapolis (USA) arriving at 7/27/2026 4:55:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 29h 40m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 40m	4:30 PM	Jacksonville, FL	Amtrak Train Station	12:10 PM	Indianapolis	Central Bus Station	Economy	$112	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 7/26/2026 4:30:00 PM to Central Bus Station, Indianapolis (USA) arriving at 7/27/2026 12:10:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 40m
FlixBus	19h 20m	9:25 PM	Jacksonville, FL	Amtrak Train Station	4:45 PM	Indianapolis	Central Bus Station	Economy	$112	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 7/26/2026 9:25:00 PM to Central Bus Station, Indianapolis (USA) arriving at 7/27/2026 4:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 20m
FlixBus	24h 20m	9:25 PM	Jacksonville, FL	Amtrak Train Station	9:45 PM	Indianapolis	Washington / Delaware	Economy	$112	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 7/26/2026 9:25:00 PM to Washington / Delaware, Indianapolis (USA) arriving at 7/27/2026 9:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 24h 20m
Greyhound US	23h 30m	10:00 AM	Jacksonville, FL	Amtrak Train Station	9:30 AM	Indianapolis	Central Bus Station	Economy	$112	A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 7/26/2026 10:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 7/27/2026 9:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 23h 30m
Greyhound US	22h 0m	10:00 AM	Jacksonville, FL	Amtrak Train Station	8:00 AM	Indianapolis	Washington / Delaware	Economy	$112	A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 7/26/2026 10:00:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 7/27/2026 8:00:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 22h 0m

Did you know that if you travel from Jacksonville, FL to Indianapolis via Atlanta, GA, you can save more than $15? You can find the corresponding connections below.
- Greyhound US
  
  20h 55m
  
  0
  
  8:00 AM
  
  Jacksonville, FL
  Downtown Bus Stop
  
  3:25 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $36
  
  A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/28/2026 8:00:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 7/28/2026 3:25:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 7h 25m
- Greyhound US
  
  11h 50m
  
  0
  
  5:05 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  4:55 AM
  
  Indianapolis
  Central Bus Station
  
  0
  
  Economy
  
  $61
  
  A Bus from Greyhound US goes from Garnett Transit Station, Atlanta, GA (USA) at 7/28/2026 5:05:00 PM to Central Bus Station, Indianapolis (USA) arriving at 7/29/2026 4:55:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 11h 50m
Travel time is 1h 35m longer, but you will save $15

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 40m	4:30 PM	Jacksonville, FL	Downtown Bus Stop	12:10 PM	Indianapolis	Central Bus Station	Economy	$99	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/30/2026 4:30:00 PM to Central Bus Station, Indianapolis (USA) arriving at 7/31/2026 12:10:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 19h 40m
FlixBus	19h 20m	9:25 PM	Jacksonville, FL	Downtown Bus Stop	4:45 PM	Indianapolis	Central Bus Station	Economy	$99	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/30/2026 9:25:00 PM to Central Bus Station, Indianapolis (USA) arriving at 7/31/2026 4:45:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 19h 20m
Greyhound US	23h 30m	10:00 AM	Jacksonville, FL	Downtown Bus Stop	9:30 AM	Indianapolis	Central Bus Station	Economy	$100	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/30/2026 10:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 7/31/2026 9:30:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 23h 30m
Greyhound US	22h 0m	10:00 AM	Jacksonville, FL	Downtown Bus Stop	8:00 AM	Indianapolis	Downtown Transit Center	Economy	$100	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/30/2026 10:00:00 AM to Downtown Transit Center, Indianapolis (USA) arriving at 7/31/2026 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 22h 0m
FlixBus	19h 50m	9:05 AM	Jacksonville, FL	Downtown Bus Stop	4:55 AM	Indianapolis	Central Bus Station	Economy	$104	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/30/2026 9:05:00 AM to Central Bus Station, Indianapolis (USA) arriving at 7/31/2026 4:55:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 19h 50m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 50m	9:05 AM	Jacksonville, FL	Downtown Bus Stop	4:55 AM	Indianapolis	Central Bus Station	Economy	$102	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/31/2026 9:05:00 AM to Central Bus Station, Indianapolis (USA) arriving at 8/1/2026 4:55:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 19h 50m
FlixBus	19h 40m	4:30 PM	Jacksonville, FL	Downtown Bus Stop	12:10 PM	Indianapolis	Central Bus Station	Economy	$102	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/31/2026 4:30:00 PM to Central Bus Station, Indianapolis (USA) arriving at 8/1/2026 12:10:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 19h 40m
FlixBus	19h 20m	9:25 PM	Jacksonville, FL	Downtown Bus Stop	4:45 PM	Indianapolis	Central Bus Station	Economy	$102	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/31/2026 9:25:00 PM to Central Bus Station, Indianapolis (USA) arriving at 8/1/2026 4:45:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 19h 20m
Greyhound US	22h 0m	10:00 AM	Jacksonville, FL	Downtown Bus Stop	8:00 AM	Indianapolis	Downtown Transit Center	Economy	$103	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/31/2026 10:00:00 AM to Downtown Transit Center, Indianapolis (USA) arriving at 8/1/2026 8:00:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 22h 0m
Greyhound US	23h 30m	10:00 AM	Jacksonville, FL	Downtown Bus Stop	9:30 AM	Indianapolis	Central Bus Station	Economy	$104	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 7/31/2026 10:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 8/1/2026 9:30:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 23h 30m

Did you know that if you travel from Jacksonville, FL to Indianapolis via Atlanta, GA, you can save more than $10? You can find the corresponding connections below.
- Greyhound US
  
  26h 10m
  
  0
  
  10:00 AM
  
  Jacksonville, FL
  Amtrak Train Station
  
  6:15 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $42
  
  A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 7/30/2026 10:00:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 7/30/2026 6:15:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 8h 15m
- FlixBus
  
  12h 11m
  
  0
  
  11:59 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  12:10 PM
  
  Indianapolis
  Central Bus Station
  
  0
  
  Economy
  
  $50
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 7/30/2026 11:59:00 PM to Central Bus Station, Indianapolis (USA) arriving at 7/31/2026 12:10:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 12h 11m
Travel time is 6h 50m longer, but you will save $10

Frequency of bus connections between Jacksonville, FL and Indianapolis

See here how frequent the connections between Jacksonville, FL and Indianapolis are, during different times and days of the week.

Thursday is the busiest day, with more than 14 daily buses from Jacksonville, FL to Indianapolis. Saturday has instead the fewest connections, with only 5 daily coaches between Jacksonville, FL and Indianapolis.

The busiest time of the day is the Evening, with 18 buses from Jacksonville, FL to Indianapolis, while Afternoon sees the fewest connections between Jacksonville, FL and Indianapolis, with 5 offers.

Test cheapest views

The cheapest bus for the 7/30/2026 costs just $99, from FlixBus

Facts about the bus from Jacksonville, FL to Indianapolis

Compare all providers like FlixBus and Greyhound US that travel 8 times every day by bus from Jacksonville, FL to Indianapolis in one click! Book your bus ticket from Jacksonville, FL to Indianapolis starting from $99!

Cheapest Bus	$99
Fastest Bus	19h 20m
Earliest Bus	4:30 PM
Latest Bus	11:15 PM
Daily Bus Routes	8 Ø
Distance	699.6 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Jacksonville, FL to Indianapolis

Every day, 8 buses from 2 bus companies leave Jacksonville, FL for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

Friday 07/24

Saturday 07/25

$104

Sunday 07/26

$112

Monday 07/27

$115

Tuesday 07/28

$102

Wednesday 07/29

Thursday 07/30

$103

Friday 07/31

$102

Saturday 08/01

Sunday 08/02

$108

Monday 08/03

$105

Tuesday 08/04

$113

Wednesday 08/05

Thursday 08/06

$106

Friday 08/07

Saturday 08/08

$109

Sunday 08/09

Monday 08/10

$105

Tuesday 08/11

$108

Wednesday 08/12

$106

Thursday 08/13

Friday 08/14

Saturday 08/15

The cheapest time to travel from Jacksonville, FL to Indianapolis

See here on which day and which time of the day you can find the cheapest bus ticket from Jacksonville, FL to Indianapolis, for the next 30 days.

With a price starting from $99, Thursday is the cheapest day for a bus from Jacksonville, FL to Indianapolis. Sunday instead is the most expensive day with prices starting from $108.

Afternoon is the cheapest day time for bus tickets from Jacksonville, FL to Indianapolis, with $99. Morning is the most expensive time of the day with prices starting from $100.

How to save money travelling from Jacksonville, FL to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Jacksonville, FL to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Jacksonville, FL to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Jacksonville, FL to Indianapolis are also emptier.

All bus stations and stops in Jacksonville, FL and Indianapolis

In the map below, you can see where to find all bus stations in Jacksonville, FL and Indianapolis.

Downtown Bus Stop

West Forsyth Street 1111

Beaver St. & Ocean St. Bus Stop

Central Bus Station

Old St. Augustine Rd

Old St. Augustine Rd 10584-13

Friendship Fountain

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Central Bus Station

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

Service and Comfort on the bus from Jacksonville, FL to Indianapolis

Want to know which seat classes are available on the buses from Jacksonville, FL to Indianapolis? Or which bus companies serve the route Jacksonville, FL to Indianapolis? Below you will find answers to your questions.

FAQs about the Jacksonville, FL to Indianapolis bus

How much does a Jacksonville, FL Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $99 and takes 19h 40m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from Jacksonville, FL to Indianapolis?

This route is offered by 2 companies with a range of ticket prices between $99 and $145. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from Jacksonville, FL to Indianapolis each day?

Every day, the Jacksonville, FL to Indianapolis bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Jacksonville, FL to Indianapolis take?

The fastest bus from Jacksonville, FL to Indianapolis is offered by FlixBus and takes 19h 20m. Bus tickets for this connection cost $106. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Jacksonville, FL to Indianapolis?

The earliest bus arriving in Indianapolis from Jacksonville, FL starts at 4:30 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Jacksonville, FL to Indianapolis?

The latest bus trip departing from Jacksonville, FL for Indianapolis starts at 11:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Jacksonville, FL Indianapolis route?

When traveling by bus from Jacksonville, FL to Indianapolis, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Jacksonville, FL and Indianapolis?

You can check all the direct connections between Jacksonville, FL and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Jacksonville, FL to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Jacksonville, FL Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Jacksonville, FL Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Jacksonville, FL to Indianapolis on your planned travel date.

Available seat classes which are offered on the bus route Jacksonville, FL to Indianapolis

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Jacksonville, FL and to Indianapolis

Here’s an overview of the most popular bus routes to Jacksonville, FL and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!