Bus Santa Ana, CA to San Diego: Compare prices and save money

Compare all timetables for the bus from Santa Ana, CA to San Diego

Here is a selection of the cheapest bus trips from the schedule from Santa Ana, CA to San Diego from various bus operators like FlixBus or Greyhound US for the next days.

today

$14

tomorrow

$13

Tuesday

$13

Wednesday

$12

Thursday

$12

Friday

$14

Saturday

$13

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	1h 45m	8:30 PM	Santa Ana, CA	Bus Stop	10:15 PM	San Diego	Seaport Village	Economy	$14	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/26/2026 8:30:00 PM to Seaport Village, San Diego (USA) arriving at 7/26/2026 10:15:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 1h 45m
FlixBus	1h 50m	2:35 PM	Santa Ana, CA	Bus Stop	4:25 PM	San Diego	Old Town Transit Center	Economy	$15	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/26/2026 2:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/26/2026 4:25:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 1h 50m
FlixBus	1h 15m	8:30 PM	Santa Ana, CA	Bus Stop	9:45 PM	San Diego	La Jolla Village	Economy	$18	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/26/2026 8:30:00 PM to La Jolla Village, San Diego (USA) arriving at 7/26/2026 9:45:00 PM. 50 Economy ticket for $18 per person are available. Travel duration is 1h 15m
Greyhound US	1h 45m	10:05 PM	Santa Ana, CA	Bus Stop	11:50 PM	San Diego	Old Town Transit Center	Economy	$27	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/26/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/26/2026 11:50:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 1h 45m
Greyhound US	1h 45m	10:00 AM	Santa Ana, CA	Bus Stop	11:45 AM	San Diego	Old Town Transit Center	Economy	$29	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/26/2026 10:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 7/26/2026 11:45:00 AM. 50 Economy ticket for $29 per person are available. Travel duration is 1h 45m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	1h 50m	2:35 PM	Santa Ana, CA	Bus Stop	4:25 PM	San Diego	Old Town Transit Center	Economy	$13	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/27/2026 2:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/27/2026 4:25:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 50m
FlixBus	1h 45m	8:30 PM	Santa Ana, CA	Bus Stop	10:15 PM	San Diego	Seaport Village	Economy	$13	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/27/2026 8:30:00 PM to Seaport Village, San Diego (USA) arriving at 7/27/2026 10:15:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 45m
FlixBus	1h 20m	2:35 PM	Santa Ana, CA	Bus Stop	3:55 PM	San Diego	La Jolla Village	Economy	$17	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/27/2026 2:35:00 PM to La Jolla Village, San Diego (USA) arriving at 7/27/2026 3:55:00 PM. 50 Economy ticket for $17 per person are available. Travel duration is 1h 20m
Greyhound US	1h 45m	10:05 PM	Santa Ana, CA	Bus Stop	11:50 PM	San Diego	Old Town Transit Center	Economy	$26	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/27/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/27/2026 11:50:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 1h 45m
Greyhound US	1h 45m	10:00 AM	Santa Ana, CA	Bus Stop	11:45 AM	San Diego	Old Town Transit Center	Economy	$27	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/27/2026 10:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 7/27/2026 11:45:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 1h 45m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	1h 50m	2:35 PM	Santa Ana, CA	Bus Stop	4:25 PM	San Diego	Old Town Transit Center	Economy	$13	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/28/2026 2:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/28/2026 4:25:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 50m
FlixBus	1h 45m	8:30 PM	Santa Ana, CA	Bus Stop	10:15 PM	San Diego	Seaport Village	Economy	$13	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/28/2026 8:30:00 PM to Seaport Village, San Diego (USA) arriving at 7/28/2026 10:15:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 45m
FlixBus	1h 15m	8:30 PM	Santa Ana, CA	Bus Stop	9:45 PM	San Diego	La Jolla Village	Economy	$16	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/28/2026 8:30:00 PM to La Jolla Village, San Diego (USA) arriving at 7/28/2026 9:45:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 1h 15m
Greyhound US	1h 45m	10:05 PM	Santa Ana, CA	Bus Stop	11:50 PM	San Diego	Old Town Transit Center	Economy	$24	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/28/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/28/2026 11:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 1h 45m
Greyhound US	1h 45m	10:00 AM	Santa Ana, CA	Bus Stop	11:45 AM	San Diego	Old Town Transit Center	Economy	$25	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/28/2026 10:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 7/28/2026 11:45:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 1h 45m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	1h 45m	8:30 PM	Santa Ana, CA	Bus Stop	10:15 PM	San Diego	Seaport Village	Economy	$12	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/29/2026 8:30:00 PM to Seaport Village, San Diego (USA) arriving at 7/29/2026 10:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 1h 45m
FlixBus	1h 50m	2:35 PM	Santa Ana, CA	Bus Stop	4:25 PM	San Diego	Old Town Transit Center	Economy	$13	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/29/2026 2:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/29/2026 4:25:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 50m
FlixBus	1h 15m	8:30 PM	Santa Ana, CA	Bus Stop	9:45 PM	San Diego	La Jolla Village	Economy	$16	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/29/2026 8:30:00 PM to La Jolla Village, San Diego (USA) arriving at 7/29/2026 9:45:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 1h 15m
Greyhound US	1h 45m	10:05 PM	Santa Ana, CA	Bus Stop	11:50 PM	San Diego	Old Town Transit Center	Economy	$24	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/29/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/29/2026 11:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 1h 45m
Greyhound US	1h 45m	10:00 AM	Santa Ana, CA	Bus Stop	11:45 AM	San Diego	Old Town Transit Center	Economy	$26	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/29/2026 10:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 7/29/2026 11:45:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 1h 45m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	1h 50m	2:35 PM	Santa Ana, CA	Bus Stop	4:25 PM	San Diego	Old Town Transit Center	Economy	$12	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/30/2026 2:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/30/2026 4:25:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 1h 50m
FlixBus	1h 45m	8:30 PM	Santa Ana, CA	Bus Stop	10:15 PM	San Diego	Seaport Village	Economy	$12	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/30/2026 8:30:00 PM to Seaport Village, San Diego (USA) arriving at 7/30/2026 10:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 1h 45m
FlixBus	1h 20m	2:35 PM	Santa Ana, CA	Bus Stop	3:55 PM	San Diego	La Jolla Village	Economy	$16	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/30/2026 2:35:00 PM to La Jolla Village, San Diego (USA) arriving at 7/30/2026 3:55:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 1h 20m
Greyhound US	1h 45m	10:05 PM	Santa Ana, CA	Bus Stop	11:50 PM	San Diego	Old Town Transit Center	Economy	$22	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/30/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/30/2026 11:50:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 1h 45m
Greyhound US	1h 45m	10:00 AM	Santa Ana, CA	Bus Stop	11:45 AM	San Diego	Old Town Transit Center	Economy	$23	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/30/2026 10:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 7/30/2026 11:45:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 1h 45m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	1h 50m	2:35 PM	Santa Ana, CA	Bus Stop	4:25 PM	San Diego	Old Town Transit Center	Economy	$14	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/31/2026 2:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/31/2026 4:25:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 1h 50m
FlixBus	1h 45m	8:30 PM	Santa Ana, CA	Bus Stop	10:15 PM	San Diego	Seaport Village	Economy	$14	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/31/2026 8:30:00 PM to Seaport Village, San Diego (USA) arriving at 7/31/2026 10:15:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 1h 45m
FlixBus	2h 35m	2:35 PM	Santa Ana, CA	Bus Stop	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$22	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 7/31/2026 2:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 7/31/2026 5:10:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 2h 35m
Greyhound US	1h 45m	10:00 AM	Santa Ana, CA	Bus Stop	11:45 AM	San Diego	Old Town Transit Center	Economy	$24	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/31/2026 10:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 7/31/2026 11:45:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 1h 45m
Greyhound US	1h 45m	10:05 PM	Santa Ana, CA	Bus Stop	11:50 PM	San Diego	Old Town Transit Center	Economy	$24	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/31/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/31/2026 11:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 1h 45m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	1h 50m	2:35 PM	Santa Ana, CA	Bus Stop	4:25 PM	San Diego	Old Town Transit Center	Economy	$13	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 8/1/2026 2:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/1/2026 4:25:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 50m
FlixBus	1h 45m	8:30 PM	Santa Ana, CA	Bus Stop	10:15 PM	San Diego	Seaport Village	Economy	$13	A Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 8/1/2026 8:30:00 PM to Seaport Village, San Diego (USA) arriving at 8/1/2026 10:15:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 45m
Greyhound US	1h 45m	10:05 PM	Santa Ana, CA	Bus Stop	11:50 PM	San Diego	Old Town Transit Center	Economy	$23	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 8/1/2026 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/1/2026 11:50:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 1h 45m
Greyhound US	1h 45m	10:00 AM	Santa Ana, CA	Bus Stop	11:45 AM	San Diego	Old Town Transit Center	Economy	$25	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 8/1/2026 10:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/1/2026 11:45:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 1h 45m

Frequency of bus connections between Santa Ana, CA and San Diego

See here how frequent the connections between Santa Ana, CA and San Diego are, during different times and days of the week.

Sunday is the busiest day, with more than 14 daily buses from Santa Ana, CA to San Diego. Saturday has instead the fewest connections, with only 4 daily coaches between Santa Ana, CA and San Diego.

The busiest time of the day is the Evening, with 37 buses from Santa Ana, CA to San Diego, while Morning sees the fewest connections between Santa Ana, CA and San Diego, with 16 offers.

Test cheapest views

The cheapest bus for the 8/12/2026 costs just $12, from FlixBus

Facts about the bus from Santa Ana, CA to San Diego

Compare all providers like FlixBus and Greyhound US that travel 10 times every day by bus from Santa Ana, CA to San Diego in one click! Book your bus ticket from Santa Ana, CA to San Diego starting from $12!

Cheapest Bus	$12
Fastest Bus	1h 15m
Earliest Bus	10:00 AM
Latest Bus	10:05 PM
Daily Bus Routes	10 Ø
Distance	82.0 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Santa Ana, CA to San Diego

Every day, 10 buses from 2 bus companies leave Santa Ana, CA for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

$14

Monday 07/27

$13

Tuesday 07/28

$21

Wednesday 07/29

$12

Thursday 07/30

$41

Friday 07/31

$22

Saturday 08/01

$33

Sunday 08/02

$14

Monday 08/03

$39

Tuesday 08/04

$12

Wednesday 08/05

$12

Thursday 08/06

$17

Friday 08/07

$18

Saturday 08/08

$13

Sunday 08/09

$14

Monday 08/10

$34

Tuesday 08/11

$12

Wednesday 08/12

$12

Thursday 08/13

$16

Friday 08/14

Saturday 08/15

Sunday 08/16

$18

Monday 08/17

$41

Tuesday 08/18

$34

Wednesday 08/19

Thursday 08/20

Friday 08/21

Saturday 08/22

The cheapest time to travel from Santa Ana, CA to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Santa Ana, CA to San Diego, for the next 30 days.

With a price starting from $12, Wednesday is the cheapest day for a bus from Santa Ana, CA to San Diego. Sunday instead is the most expensive day with prices starting from $14.

Afternoon is the cheapest day time for bus tickets from Santa Ana, CA to San Diego, with $12. Morning is the most expensive time of the day with prices starting from $23.

How to save money travelling from Santa Ana, CA to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santa Ana, CA to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santa Ana, CA to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santa Ana, CA to San Diego are also emptier.

All bus stations and stops in Santa Ana, CA and San Diego

In the map below, you can see where to find all bus stations in Santa Ana, CA and San Diego.

Bus Stop

1000 E Santa Ana Blvd 105

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

Downtown

Service and Comfort on the bus from Santa Ana, CA to San Diego

Want to know which seat classes are available on the buses from Santa Ana, CA to San Diego? Or which bus companies serve the route Santa Ana, CA to San Diego? Below you will find answers to your questions.

FAQs about the Santa Ana, CA to San Diego bus

How much does a Santa Ana, CA San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $12 and takes 1h 45m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Santa Ana, CA to San Diego?

This route is offered by 2 companies with a range of ticket prices between $12 and $34. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Santa Ana, CA to San Diego each day?

Every day, the Santa Ana, CA to San Diego bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santa Ana, CA to San Diego take?

The fastest bus from Santa Ana, CA to San Diego is offered by FlixBus and takes 1h 15m. Bus tickets for this connection cost $18. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santa Ana, CA to San Diego?

The earliest bus arriving in San Diego from Santa Ana, CA starts at 10:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santa Ana, CA to San Diego?

The latest bus trip departing from Santa Ana, CA for San Diego starts at 10:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santa Ana, CA San Diego route?

When traveling by bus from Santa Ana, CA to San Diego, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santa Ana, CA and San Diego?

You can check all the direct connections between Santa Ana, CA and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Santa Ana, CA to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santa Ana, CA San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santa Ana, CA San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santa Ana, CA to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Santa Ana, CA to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Santa Ana, CA and to San Diego

Here’s an overview of the most popular bus routes to Santa Ana, CA and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!