Bus Denver to Santa Ana, CA - Compare all Companies

Compare all timetables for the bus from Denver to Santa Ana, CA

Here is a selection of the cheapest bus trips from the schedule from Denver to Santa Ana, CA from various bus operators like Greyhound US for the next days.

today

tomorrow

$117

Friday

$121

Saturday

Sunday

$113

Monday

$111

Tuesday

$107

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 25m	11:05 AM	Denver	Union Station	11:30 AM	Santa Ana, CA	Bus Stop		Economy	$117	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/23/2026 11:05:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/24/2026 11:30:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 25h 25m
	Greyhound US	40h 20m	8:10 PM	Denver	Union Station	11:30 AM	Santa Ana, CA	Bus Stop		Economy	$119	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/23/2026 8:10:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/25/2026 11:30:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 40h 20m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	37h 25m	7:35 PM	Denver	Union Station	8:00 AM	Santa Ana, CA	Bus Stop	Economy	$121	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/24/2026 7:35:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/26/2026 8:00:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 37h 25m
Greyhound US	25h 25m	11:05 AM	Denver	Union Station	11:30 AM	Santa Ana, CA	Bus Stop	Economy	$122	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/24/2026 11:05:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/25/2026 11:30:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 25h 25m
Greyhound US	40h 20m	8:10 PM	Denver	Union Station	11:30 AM	Santa Ana, CA	Bus Stop	Economy	$126	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/24/2026 8:10:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/26/2026 11:30:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 40h 20m

Did you know that if you travel from Denver to Santa Ana, CA via Los Angeles, you can save more than $20? You can find the corresponding connections below.
- Greyhound US
  
  35h 55m
  
  0
  
  11:05 AM
  
  Denver
  Union Station
  
  1:15 PM
  
  Los Angeles
  North Hollywood
  
  0
  
  Economy
  
  $93
  
  A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/25/2026 11:05:00 AM to North Hollywood, Los Angeles (USA) arriving at 7/26/2026 1:15:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 27h 10m
- Greyhound US
  
  1h 40m
  
  0
  
  8:20 PM
  
  Los Angeles
  Union Station
  
  10:00 PM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $8
  
  A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 7/26/2026 8:20:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/26/2026 10:00:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 1h 40m
Travel time is 11h 30m longer, but you will save $20

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 25m	11:05 AM	Denver	Union Station	11:30 AM	Santa Ana, CA	Bus Stop	Economy	$113	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/26/2026 11:05:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/27/2026 11:30:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 25h 25m
Greyhound US	37h 25m	7:35 PM	Denver	Union Station	8:00 AM	Santa Ana, CA	Bus Stop	Economy	$113	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/26/2026 7:35:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/28/2026 8:00:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 37h 25m
Greyhound US	40h 20m	8:10 PM	Denver	Union Station	11:30 AM	Santa Ana, CA	Bus Stop	Economy	$115	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/26/2026 8:10:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/28/2026 11:30:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 40h 20m

Did you know that if you travel from Denver to Santa Ana, CA via Los Angeles, you can save more than $12? You can find the corresponding connections below.
- Greyhound US
  
  35h 55m
  
  0
  
  11:05 AM
  
  Denver
  Union Station
  
  1:15 PM
  
  Los Angeles
  North Hollywood
  
  0
  
  Economy
  
  $93
  
  A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/25/2026 11:05:00 AM to North Hollywood, Los Angeles (USA) arriving at 7/26/2026 1:15:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 27h 10m
- Greyhound US
  
  1h 40m
  
  0
  
  8:20 PM
  
  Los Angeles
  Union Station
  
  10:00 PM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $8
  
  A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 7/26/2026 8:20:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/26/2026 10:00:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 1h 40m
Travel time is 11h 30m longer, but you will save $12

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 25m	11:05 AM	Denver	Union Station	11:30 AM	Santa Ana, CA	Bus Stop	Economy	$111	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/27/2026 11:05:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/28/2026 11:30:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 25h 25m
Greyhound US	37h 25m	7:35 PM	Denver	Union Station	8:00 AM	Santa Ana, CA	Bus Stop	Economy	$113	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/27/2026 7:35:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/29/2026 8:00:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 37h 25m
Greyhound US	40h 20m	8:10 PM	Denver	Union Station	11:30 AM	Santa Ana, CA	Bus Stop	Economy	$117	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/27/2026 8:10:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/29/2026 11:30:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 40h 20m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 25m	11:05 AM	Denver	Union Station	11:30 AM	Santa Ana, CA	Bus Stop	Economy	$107	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/28/2026 11:05:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/29/2026 11:30:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 25h 25m
Greyhound US	37h 25m	7:35 PM	Denver	Union Station	8:00 AM	Santa Ana, CA	Bus Stop	Economy	$110	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/28/2026 7:35:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/30/2026 8:00:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 37h 25m
Greyhound US	40h 20m	8:10 PM	Denver	Union Station	11:30 AM	Santa Ana, CA	Bus Stop	Economy	$110	A Bus from Greyhound US goes from Union Station, Denver (USA) at 7/28/2026 8:10:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/30/2026 11:30:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 40h 20m

Best Price Offer: The price for the cheapest bus from Denver to Santa Ana, CA is $98 on 7/20/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Denver and Santa Ana, CA

See here how frequent the connections between Denver and Santa Ana, CA are, during different times and days of the week.

Tuesday is the busiest day, with more than 6 daily buses from Denver to Santa Ana, CA. Sunday has instead the fewest connections, with only 3 daily coaches between Denver and Santa Ana, CA.

The busiest time of the day is the Evening, with 12 buses from Denver to Santa Ana, CA, while Morning sees the fewest connections between Denver and Santa Ana, CA, with 7 offers.

Facts about the bus from Denver to Santa Ana, CA

Compare all providers like Greyhound US that travel 3 times every day by bus from Denver to Santa Ana, CA in one click! Book your bus ticket from Denver to Santa Ana, CA starting from $98!

Cheapest Bus	$98
Fastest Bus	24h 25m
Earliest Bus	11:05 AM
Latest Bus	8:10 PM
Daily Bus Routes	3 Ø
Distance	823.7 miles
Bus Companies	Greyhound US

Cheapest bus connections from Denver to Santa Ana, CA

Every day, 3 buses from 1 bus companies leave Denver for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

$117

Friday 07/24

$121

Saturday 07/25

Sunday 07/26

$117

Monday 07/27

$111

Tuesday 07/28

$111

Wednesday 07/29

$110

Thursday 07/30

$110

Friday 07/31

Saturday 08/01

$108

Sunday 08/02

$107

Monday 08/03

$117

Tuesday 08/04

$122

Wednesday 08/05

Thursday 08/06

Friday 08/07

Saturday 08/08

Sunday 08/09

$111

Monday 08/10

$101

Tuesday 08/11

$105

Wednesday 08/12

$101

Thursday 08/13

Friday 08/14

Saturday 08/15

The cheapest time to travel from Denver to Santa Ana, CA

See here on which day and which time of the day you can find the cheapest bus ticket from Denver to Santa Ana, CA, for the next 30 days.

With a price starting from $101, Monday is the cheapest day for a bus from Denver to Santa Ana, CA. Friday instead is the most expensive day with prices starting from $121.

Morning is the cheapest day time for bus tickets from Denver to Santa Ana, CA, with $107. Evening is the most expensive time of the day with prices starting from $110.

How to save money travelling from Denver to Santa Ana, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Denver to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Denver to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Denver to Santa Ana, CA are also emptier.

All bus stations and stops in Denver and Santa Ana, CA

In the map below, you can see where to find all bus stations in Denver and Santa Ana, CA.

Federal Blvd & W 19th Ave Bus Stop

Federal Blvd & W 19th Ave Federal Blvd & W 19th Ave

Union Station

Wynkoop St 1701

Bus Stop

Colorado Station

E Evans Ave 4401

19th St. Bus Station

19th St 1055

Bus Stop

1000 E Santa Ana Blvd 105

Service and Comfort on the bus from Denver to Santa Ana, CA

Want to know which seat classes are available on the buses from Denver to Santa Ana, CA? Or which bus companies serve the route Denver to Santa Ana, CA? Below you will find answers to your questions.

FAQs about the Denver to Santa Ana, CA bus

How much does a Denver Santa Ana, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $98 and takes 24h 25m to reach Santa Ana, CA. Compare offers to save money!

How much could I save by comparing buses from Denver to Santa Ana, CA?

This route is offered by 1 companies with a range of ticket prices between $98 and $126. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana, CA.

On average, how many connections are available from Denver to Santa Ana, CA each day?

Every day, the Denver to Santa Ana, CA bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Denver to Santa Ana, CA take?

The fastest bus from Denver to Santa Ana, CA is offered by Greyhound US and takes 24h 25m. Bus tickets for this connection cost $121. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Denver to Santa Ana, CA?

The earliest bus arriving in Santa Ana, CA from Denver starts at 11:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Denver to Santa Ana, CA?

The latest bus trip departing from Denver for Santa Ana, CA starts at 8:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Denver Santa Ana, CA route?

When traveling by bus from Denver to Santa Ana, CA, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Denver and Santa Ana, CA?

You can check all the direct connections between Denver and Santa Ana, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Denver to Santa Ana, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Denver Santa Ana, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Denver Santa Ana, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Denver to Santa Ana, CA on your planned travel date.

Available seat classes which are offered on the bus route Denver to Santa Ana, CA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Denver and to Santa Ana, CA

Here’s an overview of the most popular bus routes to Denver and to Santa Ana, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!