Bus Portland, OR to Santa Ana, CA - Compare all Companies

Compare all timetables for the bus from Portland, OR to Santa Ana, CA

Here is a selection of the cheapest bus trips from the schedule from Portland, OR to Santa Ana, CA from various bus operators like Greyhound US for the next days.

today

$121

tomorrow

Tuesday

Wednesday

Thursday

Friday

Saturday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	27h 10m	6:50 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$121	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 7/26/2026 6:50:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/27/2026 10:00:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 27h 10m

Did you know that if you travel from Portland, OR to Santa Ana, CA via Los Angeles, you can save more than $20? You can find the corresponding connections below.
- Greyhound US
  
  33h 25m
  
  0
  
  12:35 AM
  
  Portland, OR
  Greyhound Bus Station
  
  12:10 AM
  
  Los Angeles
  North Hollywood
  
  0
  
  Economy
  
  $94
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 7/28/2026 12:35:00 AM to North Hollywood, Los Angeles (USA) arriving at 7/29/2026 12:10:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 23h 35m
- Greyhound US
  
  1h 45m
  
  0
  
  8:15 AM
  
  Los Angeles
  Union Station
  
  10:00 AM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $7
  
  A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 7/29/2026 8:15:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/29/2026 10:00:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 1h 45m
Travel time is 6h 15m longer, but you will save $20

Best Price Offer: The price for the cheapest bus from Portland, OR to Santa Ana, CA is $121 on 7/26/2026. Flexible travelers save on ticket prices.

Facts about the bus from Portland, OR to Santa Ana, CA

Compare all providers like Greyhound US that travel 2 times every day by bus from Portland, OR to Santa Ana, CA in one click! Book your bus ticket from Portland, OR to Santa Ana, CA starting from $121!

Cheapest Bus	$121
Fastest Bus	27h 10m
Earliest Bus	6:50 PM
Latest Bus	6:50 PM
Daily Bus Routes	2 Ø
Distance	852.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Portland, OR to Santa Ana, CA

Every day, 2 buses from 1 bus companies leave Portland, OR for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

$125

Monday 07/27

Tuesday 07/28

Wednesday 07/29

$126

Thursday 07/30

Friday 07/31

Saturday 08/01

Sunday 08/02

Monday 08/03

Tuesday 08/04

Wednesday 08/05

$131

Thursday 08/06

$135

Friday 08/07

$127

Saturday 08/08

$139

Sunday 08/09

$141

Monday 08/10

Tuesday 08/11

Wednesday 08/12

$133

Thursday 08/13

Friday 08/14

Saturday 08/15

Sunday 08/16

$131

Monday 08/17

Tuesday 08/18

Wednesday 08/19

Thursday 08/20

Friday 08/21

Saturday 08/22

How to save money travelling from Portland, OR to Santa Ana, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Portland, OR to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Portland, OR to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Portland, OR to Santa Ana, CA are also emptier.

All bus stations and stops in Portland, OR and Santa Ana, CA

In the map below, you can see where to find all bus stations in Portland, OR and Santa Ana, CA.

Union Bus Station

NW 6th Ave 800

Greyhound Bus Station

NW Station Way 1090

NW Station Way

NW Station Way 1090

Portland Bolt Lloyd Center

NE 13th Ave 1060

SE 102nd & Washington Bus Stop

Bus Stop

1000 E Santa Ana Blvd 105

Service and Comfort on the bus from Portland, OR to Santa Ana, CA

Want to know which seat classes are available on the buses from Portland, OR to Santa Ana, CA? Or which bus companies serve the route Portland, OR to Santa Ana, CA? Below you will find answers to your questions.

FAQs about the Portland, OR to Santa Ana, CA bus

How much does a Portland, OR Santa Ana, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $121 and takes 27h 10m to reach Santa Ana, CA. Compare offers to save money!

How much could I save by comparing buses from Portland, OR to Santa Ana, CA?

This route is offered by 1 companies with a range of ticket prices between $121 and $125. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana, CA.

On average, how many connections are available from Portland, OR to Santa Ana, CA each day?

Every day, the Portland, OR to Santa Ana, CA bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Portland, OR to Santa Ana, CA take?

The fastest bus from Portland, OR to Santa Ana, CA is offered by Greyhound US and takes 27h 10m. Bus tickets for this connection cost $121. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Portland, OR to Santa Ana, CA?

The earliest bus arriving in Santa Ana, CA from Portland, OR starts at 6:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Portland, OR to Santa Ana, CA?

The latest bus trip departing from Portland, OR for Santa Ana, CA starts at 6:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Portland, OR Santa Ana, CA route?

When traveling by bus from Portland, OR to Santa Ana, CA, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Portland, OR and Santa Ana, CA?

You can check all the direct connections between Portland, OR and Santa Ana, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Portland, OR to Santa Ana, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Portland, OR Santa Ana, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Portland, OR Santa Ana, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Portland, OR to Santa Ana, CA on your planned travel date.

Available seat classes which are offered on the bus route Portland, OR to Santa Ana, CA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Portland, OR and to Santa Ana, CA

Here’s an overview of the most popular bus routes to Portland, OR and to Santa Ana, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!