Bus Milan to Siena - Compare all Companies

Compare all timetables for the bus from Milan to Siena

Here is a selection of the cheapest bus trips from the schedule from Milan to Siena from various bus operators like FlixBus or Itabus for the next days.

today

$13

tomorrow

$17

Monday

$20

Tuesday

$13

Wednesday

$13

Thursday

$20

Friday

$27

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	5h 40m	10:40 AM	Milan	Lampugnano Bus Station	4:20 PM	Siena	Train Station	Premium Economy	$13	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/25/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 7/25/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 5h 40m
FlixBus	5h 45m	5:35 AM	Milan	Lampugnano Bus Station	11:20 AM	Siena	Train Station	Economy	$22	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/25/2026 5:35:00 AM to Train Station, Siena (Italy) arriving at 7/25/2026 11:20:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 5h 45m
FlixBus	5h 5m	2:45 PM	Milan	San Donato Bus Station	7:50 PM	Siena	Train Station	Economy	$23	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/25/2026 2:45:00 PM to Train Station, Siena (Italy) arriving at 7/25/2026 7:50:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 5h 5m
Itabus	6h 30m	10:40 PM	Milan	Lampugnano Bus Station	5:10 AM	Siena	Train Station	Premium Economy	$23	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/25/2026 10:40:00 PM to Train Station, Siena (Italy) arriving at 7/26/2026 5:10:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 6h 30m
FlixBus	5h 0m	9:40 AM	Milan	San Donato Bus Station	2:40 PM	Siena	Train Station	Economy	$24	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/25/2026 9:40:00 AM to Train Station, Siena (Italy) arriving at 7/25/2026 2:40:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 5h 0m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	5h 40m	10:40 AM	Milan	Lampugnano Bus Station	4:20 PM	Siena	Train Station	Premium Economy	$17	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/26/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 7/26/2026 4:20:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 40m
FlixBus	6h 15m	6:15 AM	Milan	Lampugnano Bus Station	12:30 PM	Siena	Train Station	Economy	$19	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/26/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 7/26/2026 12:30:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 6h 15m
FlixBus	5h 40m	6:50 AM	Milan	San Donato Bus Station	12:30 PM	Siena	Train Station	Economy	$19	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/26/2026 6:50:00 AM to Train Station, Siena (Italy) arriving at 7/26/2026 12:30:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 5h 40m
FlixBus	5h 45m	5:35 AM	Milan	Lampugnano Bus Station	11:20 AM	Siena	Train Station	Economy	$21	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/26/2026 5:35:00 AM to Train Station, Siena (Italy) arriving at 7/26/2026 11:20:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 45m
Itabus	6h 25m	10:45 PM	Milan	Lampugnano Bus Station	5:10 AM	Siena	Train Station	Premium Economy	$28	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/26/2026 10:45:00 PM to Train Station, Siena (Italy) arriving at 7/27/2026 5:10:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 6h 25m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 45m	5:35 AM	Milan	Lampugnano Bus Station	11:20 AM	Siena	Train Station	Economy	$20	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/27/2026 5:35:00 AM to Train Station, Siena (Italy) arriving at 7/27/2026 11:20:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 5h 45m
FlixBus	5h 50m	12:25 PM	Milan	Lampugnano Bus Station	6:15 PM	Siena	Train Station	Economy	$21	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/27/2026 12:25:00 PM to Train Station, Siena (Italy) arriving at 7/27/2026 6:15:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 50m
Itabus	5h 40m	10:40 AM	Milan	Lampugnano Bus Station	4:20 PM	Siena	Central Bus Station	Economy	$21	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/27/2026 10:40:00 AM to Central Bus Station, Siena (Italy) arriving at 7/27/2026 4:20:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 40m
FlixBus	7h 25m	8:15 AM	Milan	Lampugnano Bus Station	3:40 PM	Siena	Train Station	Economy	$22	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/27/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 7/27/2026 3:40:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 7h 25m
Itabus	6h 25m	10:45 PM	Milan	Lampugnano Bus Station	5:10 AM	Siena	Train Station	Premium Economy	$23	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/27/2026 10:45:00 PM to Train Station, Siena (Italy) arriving at 7/28/2026 5:10:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 6h 25m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	5h 40m	10:40 AM	Milan	Lampugnano Bus Station	4:20 PM	Siena	Train Station	Premium Economy	$13	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 7/28/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 5h 40m
FlixBus	5h 50m	12:25 PM	Milan	Lampugnano Bus Station	6:15 PM	Siena	Train Station	Economy	$20	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 12:25:00 PM to Train Station, Siena (Italy) arriving at 7/28/2026 6:15:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 5h 50m
FlixBus	7h 25m	8:15 AM	Milan	Lampugnano Bus Station	3:40 PM	Siena	Train Station	Economy	$22	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 7/28/2026 3:40:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 7h 25m
FlixBus	6h 35m	8:20 AM	Milan	Lampugnano Bus Station	2:55 PM	Siena	Train Station	Economy	$27	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 8:20:00 AM to Train Station, Siena (Italy) arriving at 7/28/2026 2:55:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 6h 35m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	5h 40m	10:40 AM	Milan	Lampugnano Bus Station	4:20 PM	Siena	Train Station	Premium Economy	$13	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 7/29/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 5h 40m
FlixBus	5h 50m	12:25 PM	Milan	Lampugnano Bus Station	6:15 PM	Siena	Train Station	Economy	$19	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 12:25:00 PM to Train Station, Siena (Italy) arriving at 7/29/2026 6:15:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 5h 50m
FlixBus	6h 35m	8:20 AM	Milan	Lampugnano Bus Station	2:55 PM	Siena	Train Station	Economy	$23	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 8:20:00 AM to Train Station, Siena (Italy) arriving at 7/29/2026 2:55:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 6h 35m
FlixBus	6h 50m	3:30 PM	Milan	Lampugnano Bus Station	10:20 PM	Siena	Train Station	Economy	$23	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 3:30:00 PM to Train Station, Siena (Italy) arriving at 7/29/2026 10:20:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 6h 50m
Itabus	11h 29m	1:35 PM	Milan	San Donato Bus Station	1:04 AM	Siena	Train Station	Premium Economy	$54	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 7/29/2026 1:35:00 PM to Train Station, Siena (Italy) arriving at 7/30/2026 1:04:00 AM. 50 Premium Economy ticket for $54 per person are available. Travel duration is 11h 29m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 50m	12:25 PM	Milan	Lampugnano Bus Station	6:15 PM	Siena	Train Station	Economy	$20	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/30/2026 12:25:00 PM to Train Station, Siena (Italy) arriving at 7/30/2026 6:15:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 5h 50m
Itabus	5h 40m	10:40 AM	Milan	Lampugnano Bus Station	4:20 PM	Siena	Train Station	Premium Economy	$20	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/30/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 7/30/2026 4:20:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 5h 40m
FlixBus	5h 0m	9:40 AM	Milan	San Donato Bus Station	2:40 PM	Siena	Train Station	Economy	$21	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/30/2026 9:40:00 AM to Train Station, Siena (Italy) arriving at 7/30/2026 2:40:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 0m
FlixBus	6h 15m	6:15 AM	Milan	Lampugnano Bus Station	12:30 PM	Siena	Train Station	Economy	$22	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/30/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 7/30/2026 12:30:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 6h 15m
Itabus	6h 25m	10:45 PM	Milan	Lampugnano Bus Station	5:10 AM	Siena	Train Station	Premium Economy	$28	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/30/2026 10:45:00 PM to Train Station, Siena (Italy) arriving at 7/31/2026 5:10:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 6h 25m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	5h 40m	10:40 AM	Milan	Lampugnano Bus Station	4:20 PM	Siena	Train Station	Premium Economy	$27	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/31/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 7/31/2026 4:20:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 5h 40m
Itabus	6h 25m	10:45 PM	Milan	Lampugnano Bus Station	5:10 AM	Siena	Train Station	Premium Economy	$41	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/31/2026 10:45:00 PM to Train Station, Siena (Italy) arriving at 8/1/2026 5:10:00 AM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 6h 25m
Itabus	5h 40m	11:30 PM	Milan	San Donato Bus Station	5:10 AM	Siena	Train Station	Premium Economy	$41	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 7/31/2026 11:30:00 PM to Train Station, Siena (Italy) arriving at 8/1/2026 5:10:00 AM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 5h 40m

Best Price Offer: The price for the cheapest bus from Milan to Siena is $10 on 7/21/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Milan and Siena

See here how frequent the connections between Milan and Siena are, during different times and days of the week.

Saturday is the busiest day, with more than 28 daily buses from Milan to Siena. Friday has instead the fewest connections, with only 4 daily coaches between Milan and Siena.

The busiest time of the day is the Morning, with 49 buses from Milan to Siena, while Evening sees the fewest connections between Milan and Siena, with 18 offers.

Facts about the bus from Milan to Siena

Compare all providers like FlixBus and Itabus that travel 18 times every day by bus from Milan to Siena in one click! Book your bus ticket from Milan to Siena starting from $10!

Cheapest Bus	$10
Fastest Bus	4h 20m
Earliest Bus	12:35 AM
Latest Bus	11:30 PM
Daily Bus Routes	18 Ø
Distance	182.3 miles
Bus Companies	FlixBus and Itabus

Cheapest bus connections from Milan to Siena

Every day, 18 buses from 2 bus companies leave Milan for Siena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

Friday 07/24

Saturday 07/25

$13

Sunday 07/26

$17

Monday 07/27

$23

Tuesday 07/28

$13

Wednesday 07/29

$13

Thursday 07/30

$21

Friday 07/31

$21

Saturday 08/01

$15

Sunday 08/02

$18

Monday 08/03

$19

Tuesday 08/04

$15

Wednesday 08/05

Thursday 08/06

$26

Friday 08/07

$38

Saturday 08/08

$29

Sunday 08/09

$21

Monday 08/10

$21

Tuesday 08/11

$23

Wednesday 08/12

$23

Thursday 08/13

$23

Friday 08/14

Saturday 08/15

The cheapest time to travel from Milan to Siena

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Siena, for the next 30 days.

With a price starting from $13, Tuesday is the cheapest day for a bus from Milan to Siena. Friday instead is the most expensive day with prices starting from $21.

Morning is the cheapest day time for bus tickets from Milan to Siena, with $13. Evening is the most expensive time of the day with prices starting from $23.

How to save money travelling from Milan to Siena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Siena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Siena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Siena are also emptier.

Beloved bus companies from Milan to Siena

These are the most booked bus companies between Milan to Siena from our users.

FlixBus from Milan to Siena

Here you will find the key facts about the FlixBus bus route Milan to Siena:

Cheapest Price	$19
Fastest Bus	4h 20m
Earliest Bus	12:35 AM
Last Bus	5:05 PM
Daily Connections	14 Ø
Found on	6/28/2026

All bus stations and stops in Milan and Siena

In the map below, you can see where to find all bus stations in Milan and Siena.

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Central Bus Station

Duomo Bus Stop

Piazza del Duomo

Piazza Antonio Gramsci

Central Bus Station

Bus Stop

Viale Pietro Toselli 9

Colonna San Marco

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Siena? Compare all modes of transports from Milan to Siena.

Service and Comfort on the bus from Milan to Siena

Want to know which seat classes are available on the buses from Milan to Siena? Or which bus companies serve the route Milan to Siena? Below you will find answers to your questions.

FAQs about the Milan to Siena bus

How much does a Milan Siena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $10 and takes 5h 40m to reach Siena. Compare offers to save money!

How much could I save by comparing buses from Milan to Siena?

This route is offered by 2 companies with a range of ticket prices between $10 and $61. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Siena.

On average, how many connections are available from Milan to Siena each day?

Every day, the Milan to Siena bus route is served by approximately 18 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milan to Siena take?

The fastest bus from Milan to Siena is offered by FlixBus and takes 4h 20m. Bus tickets for this connection cost $42. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milan to Siena?

The earliest bus arriving in Siena from Milan starts at 12:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milan to Siena?

The latest bus trip departing from Milan for Siena starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milan Siena route?

When traveling by bus from Milan to Siena, passengers can travel with FlixBus and Itabus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milan and Siena?

You can check all the direct connections between Milan and Siena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Itabus.

What can I take with me on the Milan to Siena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milan Siena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Siena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Siena on your planned travel date.

Available seat classes which are offered on the bus route Milan to Siena

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Milan and to Siena

Here’s an overview of the most popular bus routes to Milan and to Siena. Simply click on the connection of your choice, and you will find all the details about your bus route!