Bus from Palermo to Milan from $60

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Compare all timetables for the bus from Palermo to Milan

Here is a selection of the cheapest bus trips from the schedule from Palermo to Milan from various bus operators like FlixBus for the next days.
today
$106
tomorrow
$92
Wednesday
$114
Thursday
$103
Friday
$107
Saturday
$109
Sunday
$100

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 40m 9:10 AM Palermo Via Tommaso Fazello Bus Stop 7:50 AM Milan San Donato Bus Station  Economy $106
FlixBus 23h 25m 9:10 AM Palermo Via Tommaso Fazello Bus Stop 8:35 AM Milan Lampugnano Bus Station  Economy $107
FlixBus 25h 10m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 10:20 PM Milan San Donato Bus Station  Economy $120
FlixBus 24h 30m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 9:40 PM Milan Lampugnano Bus Station  Economy $120
FlixBus 23h 10m 3:25 PM Palermo Via Tommaso Fazello Bus Stop 2:35 PM Milan San Donato Bus Station  Economy $126

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 20m 9:10 AM Palermo Via Tommaso Fazello Bus Stop 9:30 AM Milan Lampugnano Bus Station  Economy $92
FlixBus 23h 45m 9:10 AM Palermo Via Tommaso Fazello Bus Stop 8:55 AM Milan San Donato Bus Station  Economy $93
FlixBus 24h 30m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 9:40 PM Milan Lampugnano Bus Station  Economy $103
FlixBus 23h 10m 3:25 PM Palermo Via Tommaso Fazello Bus Stop 2:35 PM Milan San Donato Bus Station  Economy $110
FlixBus 22h 20m 3:25 PM Palermo Via Tommaso Fazello Bus Stop 1:45 PM Milan Lampugnano Bus Station  Economy $110

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 45m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 8:55 PM Milan San Donato Bus Station  Economy $114
FlixBus 22h 20m 3:25 PM Palermo Via Tommaso Fazello Bus Stop 1:45 PM Milan Lampugnano Bus Station  Economy $121
FlixBus 24h 30m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 9:40 PM Milan Lampugnano Bus Station  Economy $121
FlixBus 23h 10m 3:25 PM Palermo Via Tommaso Fazello Bus Stop 2:35 PM Milan San Donato Bus Station  Economy $124
  • Did you know that if you travel from Palermo to Milan via Lucca, you can save more than $16? You can find the corresponding connections below.
    • FlixBus
      30h 20m
      0
      3:25 PM
      Palermo
      Via Tommaso Fazello Bus Stop
      2:45 PM
      Lucca
      Central Station
      0
      FlixBus
      Economy
      $74
      • Waiting Time 0h 5m
    • FlixBus
      6h 55m
      0
      2:50 PM
      Lucca
      Central Station
      9:45 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $24
    Travel time is 8h 0m longer, but you will save $16

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 45m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 8:55 PM Milan San Donato Bus Station  Economy $103
FlixBus 26h 25m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 11:35 PM Milan Lampugnano Bus Station  Economy $107
FlixBus 23h 10m 3:25 PM Palermo Via Tommaso Fazello Bus Stop 2:35 PM Milan San Donato Bus Station  Economy $121
FlixBus 22h 20m 3:25 PM Palermo Via Tommaso Fazello Bus Stop 1:45 PM Milan Lampugnano Bus Station  Economy $121

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 25m 9:10 AM Palermo Via Tommaso Fazello Bus Stop 8:35 AM Milan Lampugnano Bus Station  Economy $107
FlixBus 22h 40m 9:10 AM Palermo Via Tommaso Fazello Bus Stop 7:50 AM Milan San Donato Bus Station  Economy $108
FlixBus 23h 45m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 8:55 PM Milan San Donato Bus Station  Economy $122
FlixBus 24h 30m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 9:40 PM Milan Lampugnano Bus Station  Economy $127
FlixBus 23h 10m 3:25 PM Palermo Via Tommaso Fazello Bus Stop 2:35 PM Milan San Donato Bus Station  Economy $163

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 25m 9:10 AM Palermo Via Tommaso Fazello Bus Stop 8:35 AM Milan Lampugnano Bus Station  Economy $109
FlixBus 22h 40m 9:10 AM Palermo Via Tommaso Fazello Bus Stop 7:50 AM Milan San Donato Bus Station  Economy $110
FlixBus 23h 10m 3:25 PM Palermo Via Tommaso Fazello Bus Stop 2:35 PM Milan San Donato Bus Station  Economy $112
FlixBus 23h 45m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 8:55 PM Milan San Donato Bus Station  Economy $112
FlixBus 24h 30m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 9:40 PM Milan Lampugnano Bus Station  Economy $113
  • Did you know that if you travel from Palermo to Milan via Lucca, you can save more than $11? You can find the corresponding connections below.
    • FlixBus
      30h 20m
      0
      3:25 PM
      Palermo
      Via Tommaso Fazello Bus Stop
      2:45 PM
      Lucca
      Central Station
      0
      FlixBus
      Economy
      $74
      • Waiting Time 0h 5m
    • FlixBus
      6h 55m
      0
      2:50 PM
      Lucca
      Central Station
      9:45 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $24
    Travel time is 7h 40m longer, but you will save $11

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 45m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 8:55 PM Milan San Donato Bus Station  Economy $100
FlixBus 24h 30m 9:10 PM Palermo Via Tommaso Fazello Bus Stop 9:40 PM Milan Lampugnano Bus Station  Economy $104
FlixBus 23h 25m 9:10 AM Palermo Via Tommaso Fazello Bus Stop 8:35 AM Milan Lampugnano Bus Station  Economy $110
FlixBus 22h 40m 9:10 AM Palermo Via Tommaso Fazello Bus Stop 7:50 AM Milan San Donato Bus Station  Economy $111
FlixBus 23h 10m 3:25 PM Palermo Via Tommaso Fazello Bus Stop 2:35 PM Milan San Donato Bus Station  Economy $152

Frequency of bus connections between Palermo and Milan

See here how frequent the connections between Palermo and Milan are, during different times and days of the week.
Sunday is the busiest day, with more than 6 daily buses from Palermo to Milan. Wednesday has instead the fewest connections, with only 4 daily coaches between Palermo and Milan.
The busiest time of the day is the Afternoon, with 14 buses from Palermo to Milan, while Morning sees the fewest connections between Palermo and Milan, with 10 offers.

Test cheapest views

The cheapest bus for the 9/28/2026 costs just $60, from FlixBus

Facts about the bus from Palermo to Milan

Compare all providers like FlixBus that travel 5 times every day by bus from Palermo to Milan in one click! Book your bus ticket from Palermo to Milan starting from $60!

Cheapest Bus $60
Fastest Bus 22h 20m
Earliest Bus 9:10 AM
Latest Bus 9:10 PM
Daily Bus Routes 5 Ø
Distance 551.5 miles
Bus Companies FlixBus

Cheapest bus connections from Palermo to Milan

Every day, 5 buses from 1 bus companies leave Palermo for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/07/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 09/06
Monday 09/07
$107
Tuesday 09/08
$92
Wednesday 09/09
$114
Thursday 09/10
$99
Friday 09/11
$110
Saturday 09/12
$109
Sunday 09/13
$98
Monday 09/14
$73
Tuesday 09/15
$107
Wednesday 09/16
$93
Thursday 09/17
$65
Friday 09/18
$75
Saturday 09/19
$100
Sunday 09/20
$84
Monday 09/21
$63
Tuesday 09/22
Wednesday 09/23
$70
Thursday 09/24
Friday 09/25
Saturday 09/26
$93
Sunday 09/27
Monday 09/28
$60
Tuesday 09/29
Wednesday 09/30
$63
Thursday 10/01
$69
Friday 10/02
$68
Saturday 10/03

The cheapest time to travel from Palermo to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Palermo to Milan, for the next 30 days.
With a price starting from $60, Monday is the cheapest day for a bus from Palermo to Milan. Saturday instead is the most expensive day with prices starting from $93.
Morning is the cheapest day time for bus tickets from Palermo to Milan, with $92. Afternoon is the most expensive time of the day with prices starting from $110.

How to save money travelling from Palermo to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Palermo to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Palermo to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Palermo to Milan are also emptier.

All bus stations and stops in Palermo and Milan

In the map below, you can see where to find all bus stations in Palermo and Milan.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Palermo to Milan? Compare all modes of transports from Palermo to Milan.

Service and Comfort on the bus from Palermo to Milan

Want to know which seat classes are available on the buses from Palermo to Milan? Or which bus companies serve the route Palermo to Milan? Below you will find answers to your questions.

FAQs about the Palermo to Milan bus

How much does a Palermo Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $60 and takes 24h 20m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Palermo to Milan?

This route is offered by 1 companies with a range of ticket prices between $60 and $180. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Palermo to Milan each day?

Every day, the Palermo to Milan bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Palermo to Milan take?

The fastest bus from Palermo to Milan is offered by FlixBus and takes 22h 20m. Bus tickets for this connection cost $137. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Palermo to Milan?

The earliest bus arriving in Milan from Palermo starts at 9:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Palermo to Milan?

The latest bus trip departing from Palermo for Milan starts at 9:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Palermo Milan route?

When traveling by bus from Palermo to Milan, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Palermo and Milan?

You can check all the direct connections between Palermo and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Palermo to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Palermo Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Palermo Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Palermo to Milan on your planned travel date.

Available seat classes which are offered on the bus route Palermo to Milan

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Palermo and to Milan

Here’s an overview of the most popular bus routes to Palermo and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from Piazza Armerina to Palermo Bus from Piazza Armerina to Palermo
Bus to Palermo from Castrovillari Bus to Palermo from Castrovillari
Enna to Palermo bus Enna to Palermo bus
Bus to Palermo from Vittoria Bus to Palermo from Vittoria
Buses to Milan from Altamura Buses to Milan from Altamura
From Cremona to Milan bus From Cremona to Milan bus
Caserta to Milan bus Caserta to Milan bus
From Zurich to Milan bus From Zurich to Milan bus
Popular Airport Shuttles to Palermo and to Milan
CheckMyBus › Buses in Italy › Bus to Palermo › Bus to Milan

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