Bus from Prague to Milan from $50

Compare 1 companies and find the best price with CheckMyBus
Search for your destination Millions of deals worldwide
Compare results Save up to 70%
Find the right bus for you Easy and transparent

Compare all timetables for the bus from Prague to Milan

Here is a selection of the cheapest bus trips from the schedule from Prague to Milan from various bus operators like FlixBus for the next days.
today
$65
tomorrow
$56
Thursday
$56
Friday
$64
Saturday
$64
Sunday
$66
Monday
$55

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 15m 5:15 PM Prague ÚAN Florenc 10:30 AM Milan San Donato Bus Station  Economy $65
FlixBus 17h 30m 11:40 PM Prague ÚAN Florenc 5:10 PM Milan San Donato Bus Station  Economy $65
FlixBus 17h 0m 5:30 PM Prague Wilsonova Bus Station 10:30 AM Milan San Donato Bus Station  Economy $65
FlixBus 15h 35m 8:10 PM Prague ÚAN Florenc 11:45 AM Milan Lampugnano Bus Station  Economy $66
FlixBus 15h 25m 9:25 PM Prague ÚAN Florenc 12:50 PM Milan Lampugnano Bus Station  Economy $66
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $10? You can find the corresponding connections below.
    • RegioJet
      13h 35m
      0
      9:30 AM
      Prague
      ÚAN Florenc
      2:15 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 1h 25m
    • FlixBus
      7h 25m
      0
      3:40 PM
      Munich
      Central Bus Station
      11:05 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $41
    Travel Time is 1h 50m shorter, and you will save $10

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 30m 6:30 PM Prague Wilsonova Bus Station 9:00 AM Milan Lampugnano Bus Station  Economy $56
FlixBus 14h 40m 6:20 PM Prague ÚAN Florenc 9:00 AM Milan Lampugnano Bus Station  Economy $56
FlixBus 15h 0m 2:30 AM Prague Wilsonova Bus Station 5:30 PM Milan Lampugnano Bus Station  Economy $59
FlixBus 17h 20m 11:50 PM Prague Wilsonova Bus Station 5:10 PM Milan San Donato Bus Station  Economy $60
FlixBus 18h 15m 9:50 PM Prague Na Knížecí Station 4:05 PM Milan Lampugnano Bus Station  Economy $60

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 30m 6:30 PM Prague Wilsonova Bus Station 9:00 AM Milan Lampugnano Bus Station  Economy $56
FlixBus 14h 40m 6:20 PM Prague ÚAN Florenc 9:00 AM Milan Lampugnano Bus Station  Economy $56
FlixBus 14h 55m 11:50 PM Prague Wilsonova Bus Station 2:45 PM Milan Lampugnano Bus Station  Economy $61
FlixBus 19h 25m 3:40 AM Prague Na Knížecí Station 11:05 PM Milan Lampugnano Bus Station  Economy $61
FlixBus 16h 35m 9:40 AM Prague Na Knížecí Station 2:15 AM Milan Lampugnano Bus Station  Economy $61
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $11? You can find the corresponding connections below.
    • RegioJet
      13h 30m
      0
      5:00 PM
      Prague
      ÚAN Florenc
      9:45 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 2h 5m
    • FlixBus
      6h 40m
      0
      11:50 PM
      Munich
      Central Bus Station
      6:30 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $31
    Travel Time is 1h 0m shorter, and you will save $11

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 30m 6:30 PM Prague Wilsonova Bus Station 9:00 AM Milan Lampugnano Bus Station  Economy $64
FlixBus 14h 40m 6:20 PM Prague ÚAN Florenc 9:00 AM Milan Lampugnano Bus Station  Economy $64
FlixBus 18h 30m 2:30 AM Prague Wilsonova Bus Station 9:00 PM Milan San Donato Bus Station  Economy $68
FlixBus 16h 55m 9:50 PM Prague Na Knížecí Station 2:45 PM Milan Lampugnano Bus Station  Economy $68
FlixBus 17h 30m 11:40 PM Prague ÚAN Florenc 5:10 PM Milan San Donato Bus Station  Economy $68
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $19? You can find the corresponding connections below.
    • RegioJet
      13h 30m
      0
      5:00 PM
      Prague
      ÚAN Florenc
      9:45 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 2h 5m
    • FlixBus
      6h 40m
      0
      11:50 PM
      Munich
      Central Bus Station
      6:30 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $31
    Travel Time is 1h 0m shorter, and you will save $19

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 30m 6:30 PM Prague Wilsonova Bus Station 9:00 AM Milan Lampugnano Bus Station  Economy $64
FlixBus 14h 40m 6:20 PM Prague ÚAN Florenc 9:00 AM Milan Lampugnano Bus Station  Economy $64
FlixBus 16h 55m 9:50 PM Prague Na Knížecí Station 2:45 PM Milan Lampugnano Bus Station  Economy $68
FlixBus 13h 45m 7:25 PM Prague Zličín 9:10 AM Milan Lampugnano Bus Station  Economy $68
FlixBus 18h 30m 2:30 AM Prague Wilsonova Bus Station 9:00 PM Milan San Donato Bus Station  Economy $69
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $19? You can find the corresponding connections below.
    • RegioJet
      13h 30m
      0
      5:00 PM
      Prague
      ÚAN Florenc
      9:45 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 2h 5m
    • FlixBus
      6h 40m
      0
      11:50 PM
      Munich
      Central Bus Station
      6:30 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $31
    Travel Time is 0h 15m shorter, and you will save $19

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 30m 6:30 PM Prague Wilsonova Bus Station 9:00 AM Milan Lampugnano Bus Station  Economy $66
FlixBus 14h 40m 6:20 PM Prague ÚAN Florenc 9:00 AM Milan Lampugnano Bus Station  Economy $66
FlixBus 12h 35m 2:15 PM Prague Wilsonova Bus Station 2:50 AM Milan Lampugnano Bus Station  Economy $75
FlixBus 12h 50m 2:00 PM Prague ÚAN Florenc 2:50 AM Milan Lampugnano Bus Station  Economy $75
FlixBus 15h 15m 5:45 PM Prague Na Knížecí Station 9:00 AM Milan Lampugnano Bus Station  Economy $75
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $21? You can find the corresponding connections below.
    • RegioJet
      13h 30m
      0
      5:00 PM
      Prague
      ÚAN Florenc
      9:45 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 2h 5m
    • FlixBus
      6h 40m
      0
      11:50 PM
      Munich
      Central Bus Station
      6:30 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $31
    Travel time is 0h 55m longer, but you will save $21

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 30m 6:30 PM Prague Wilsonova Bus Station 9:00 AM Milan Lampugnano Bus Station  Economy $55
FlixBus 14h 40m 6:20 PM Prague ÚAN Florenc 9:00 AM Milan Lampugnano Bus Station  Economy $55
FlixBus 19h 25m 3:40 AM Prague Na Knížecí Station 11:05 PM Milan Lampugnano Bus Station  Economy $64
FlixBus 15h 55m 10:55 AM Prague Na Knížecí Station 2:50 AM Milan Lampugnano Bus Station  Economy $64
FlixBus 15h 15m 5:45 PM Prague Na Knížecí Station 9:00 AM Milan Lampugnano Bus Station  Economy $64
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $10? You can find the corresponding connections below.
    • RegioJet
      13h 30m
      0
      5:00 PM
      Prague
      ÚAN Florenc
      9:45 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 2h 5m
    • FlixBus
      6h 40m
      0
      11:50 PM
      Munich
      Central Bus Station
      6:30 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $31
    Travel Time is 1h 0m shorter, and you will save $10

Frequency of bus connections between Prague and Milan

See here how frequent the connections between Prague and Milan are, during different times and days of the week.
Saturday is the busiest day, with more than 39 daily buses from Prague to Milan. Tuesday has instead the fewest connections, with only 23 daily coaches between Prague and Milan.
The busiest time of the day is the Evening, with 95 buses from Prague to Milan, while Night sees the fewest connections between Prague and Milan, with 15 offers.

Test cheapest views

The cheapest bus for the 9/16/2026 costs just $50, from FlixBus

Facts about the bus from Prague to Milan

Compare all providers like FlixBus that travel 33 times every day by bus from Prague to Milan in one click! Book your bus ticket from Prague to Milan starting from $50!

Cheapest Bus $50
Fastest Bus 12h 35m
Earliest Bus 12:50 PM
Latest Bus 11:50 PM
Daily Bus Routes 33 Ø
Distance 401.1 miles
Bus Companies FlixBus

Cheapest bus connections from Prague to Milan

Every day, 33 buses from 1 bus companies leave Prague for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/08/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 09/06
Monday 09/07
Tuesday 09/08
$67
Wednesday 09/09
Thursday 09/10
$58
Friday 09/11
$72
Saturday 09/12
$64
Sunday 09/13
$66
Monday 09/14
$59
Tuesday 09/15
$62
Wednesday 09/16
$50
Thursday 09/17
$52
Friday 09/18
$59
Saturday 09/19
Sunday 09/20
$62
Monday 09/21
$53
Tuesday 09/22
$65
Wednesday 09/23
$90
Thursday 09/24
Friday 09/25
Saturday 09/26
$59
Sunday 09/27
Monday 09/28
Tuesday 09/29
Wednesday 09/30
Thursday 10/01
Friday 10/02
Saturday 10/03

The cheapest time to travel from Prague to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Milan, for the next 30 days.
With a price starting from $50, Wednesday is the cheapest day for a bus from Prague to Milan. Tuesday instead is the most expensive day with prices starting from $62.
Night is the cheapest day time for bus tickets from Prague to Milan, with $50. Morning is the most expensive time of the day with prices starting from $61.

How to save money travelling from Prague to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Milan are also emptier.

All bus stations and stops in Prague and Milan

In the map below, you can see where to find all bus stations in Prague and Milan.

Service and Comfort on the bus from Prague to Milan

Want to know which seat classes are available on the buses from Prague to Milan? Or which bus companies serve the route Prague to Milan? Below you will find answers to your questions.

FAQs about the Prague to Milan bus

How much does a Prague Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $50 and takes 14h 30m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Prague to Milan?

This route is offered by 1 companies with a range of ticket prices between $50 and $141. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Prague to Milan each day?

Every day, the Prague to Milan bus route is served by approximately 33 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Prague to Milan take?

The fastest bus from Prague to Milan is offered by FlixBus and takes 12h 35m. Bus tickets for this connection cost $75. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Prague to Milan?

The earliest bus arriving in Milan from Prague starts at 12:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Prague to Milan?

The latest bus trip departing from Prague for Milan starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Prague Milan route?

When traveling by bus from Prague to Milan, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Prague and Milan?

You can check all the direct connections between Prague and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Prague to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Prague Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Milan on your planned travel date.

Available seat classes which are offered on the bus route Prague to Milan

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Milan

Here’s an overview of the most popular bus routes to Prague and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses to Prague from Split Buses to Prague from Split
Bus from Sibiu to Prague Bus from Sibiu to Prague
Bus Enschede - Prague Bus Enschede - Prague
Bus to Prague from Nuremberg Bus to Prague from Nuremberg
From Pisa to Milan bus From Pisa to Milan bus
Buses to Milan from Perpignan Buses to Milan from Perpignan
Buses Mulhouse - Milan Buses Mulhouse - Milan
Bus Nuremberg - Milan Bus Nuremberg - Milan
Popular Airport Shuttles to Prague and to Milan
CheckMyBus › Buses in Czech Republic › Bus to Prague › Bus to Milan

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.