Compare all timetables for the bus from Rome to Prague
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 20h 30m | 9:00 PM | Rome | Tiburtina Bus Station | 5:30 PM | Prague | Wilsonova Bus Station | Economy | $100 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/7/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/8/2026 5:30:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 20h 30m
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| FlixBus | 26h 55m | 9:00 PM | Rome | Tiburtina Bus Station | 11:55 PM | Prague | Wilsonova Bus Station | Economy | $100 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/7/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/8/2026 11:55:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 26h 55m
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| FlixBus | 23h 20m | 9:00 PM | Rome | Tiburtina Bus Station | 8:20 PM | Prague | Na Knížecí Station | Economy | $100 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/7/2026 9:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/8/2026 8:20:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 23h 20m
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| FlixBus | 20h 45m | 9:00 PM | Rome | Tiburtina Bus Station | 5:45 PM | Prague | ÚAN Florenc | Economy | $100 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/7/2026 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/8/2026 5:45:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 20h 45m
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| FlixBus | 27h 0m | 5:00 PM | Rome | Tiburtina Bus Station | 8:00 PM | Prague | Wilsonova Bus Station | Economy | $103 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/7/2026 5:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/8/2026 8:00:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 27h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 45m | 10:45 PM | Rome | Tiburtina Bus Station | 9:30 PM | Prague | Černý Most | Economy | $84 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/8/2026 10:45:00 PM to Černý Most, Prague (Czech Republic) arriving at 9/9/2026 9:30:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 22h 45m
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| FlixBus | 20h 30m | 9:00 PM | Rome | Tiburtina Bus Station | 5:30 PM | Prague | Wilsonova Bus Station | Economy | $85 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/8/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/9/2026 5:30:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 20h 30m
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| FlixBus | 22h 45m | 9:20 PM | Rome | Tiburtina Bus Station | 8:05 PM | Prague | Wilsonova Bus Station | Economy | $85 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/8/2026 9:20:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/9/2026 8:05:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 22h 45m
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| FlixBus | 23h 20m | 9:00 PM | Rome | Tiburtina Bus Station | 8:20 PM | Prague | Na Knížecí Station | Economy | $85 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/8/2026 9:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/9/2026 8:20:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 23h 20m
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| FlixBus | 20h 45m | 9:00 PM | Rome | Tiburtina Bus Station | 5:45 PM | Prague | ÚAN Florenc | Economy | $85 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/8/2026 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/9/2026 5:45:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 20h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 27h 0m | 5:00 PM | Rome | Tiburtina Bus Station | 8:00 PM | Prague | Wilsonova Bus Station | Economy | $106 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/9/2026 5:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/10/2026 8:00:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 27h 0m
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| FlixBus | 21h 30m | 9:30 AM | Rome | Tiburtina Bus Station | 7:00 AM | Prague | Wilsonova Bus Station | Economy | $107 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/9/2026 9:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/10/2026 7:00:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 21h 30m
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| FlixBus | 20h 20m | 5:00 PM | Rome | Tiburtina Bus Station | 1:20 PM | Prague | Wilsonova Bus Station | Economy | $107 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/9/2026 5:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/10/2026 1:20:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 20h 20m
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| FlixBus | 20h 30m | 9:00 PM | Rome | Tiburtina Bus Station | 5:30 PM | Prague | Wilsonova Bus Station | Economy | $107 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/9/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/10/2026 5:30:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 20h 30m
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| FlixBus | 22h 10m | 9:00 PM | Rome | Tiburtina Bus Station | 7:10 PM | Prague | Na Knížecí Station | Economy | $107 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/9/2026 9:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/10/2026 7:10:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 22h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 20h 45m | 9:00 PM | Rome | Tiburtina Bus Station | 5:45 PM | Prague | ÚAN Florenc | Economy | $95 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/11/2026 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/12/2026 5:45:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 20h 45m
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| FlixBus | 20h 30m | 9:00 PM | Rome | Tiburtina Bus Station | 5:30 PM | Prague | Wilsonova Bus Station | Economy | $95 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/11/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/12/2026 5:30:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 20h 30m
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| FlixBus | 22h 55m | 11:40 AM | Rome | Tiburtina Bus Station | 10:35 AM | Prague | Wilsonova Bus Station | Economy | $96 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/11/2026 11:40:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/12/2026 10:35:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 22h 55m
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| FlixBus | 22h 10m | 9:00 PM | Rome | Tiburtina Bus Station | 7:10 PM | Prague | Na Knížecí Station | Economy | $96 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/11/2026 9:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/12/2026 7:10:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 22h 10m
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| FlixBus | 28h 30m | 9:30 AM | Rome | Tiburtina Bus Station | 2:00 PM | Prague | Wilsonova Bus Station | Economy | $105 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/11/2026 9:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/12/2026 2:00:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 28h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 20h 45m | 9:00 PM | Rome | Tiburtina Bus Station | 5:45 PM | Prague | ÚAN Florenc | Economy | $97 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/12/2026 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/13/2026 5:45:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 20h 45m
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| FlixBus | 20h 30m | 9:00 PM | Rome | Tiburtina Bus Station | 5:30 PM | Prague | Wilsonova Bus Station | Economy | $97 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/12/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/13/2026 5:30:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 20h 30m
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| FlixBus | 26h 55m | 9:00 PM | Rome | Tiburtina Bus Station | 11:55 PM | Prague | Wilsonova Bus Station | Economy | $99 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/12/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/13/2026 11:55:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 26h 55m
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| FlixBus | 20h 35m | 10:55 PM | Rome | Tiburtina Bus Station | 7:30 PM | Prague | ÚAN Florenc | Economy | $102 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/12/2026 10:55:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/13/2026 7:30:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 20h 35m
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| FlixBus | 20h 25m | 10:55 PM | Rome | Tiburtina Bus Station | 7:20 PM | Prague | Wilsonova Bus Station | Economy | $102 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/12/2026 10:55:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/13/2026 7:20:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 20h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 20h 45m | 9:00 PM | Rome | Tiburtina Bus Station | 5:45 PM | Prague | ÚAN Florenc | Economy | $92 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/13/2026 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/14/2026 5:45:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 20h 45m
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| FlixBus | 20h 30m | 9:00 PM | Rome | Tiburtina Bus Station | 5:30 PM | Prague | Wilsonova Bus Station | Economy | $92 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/13/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/14/2026 5:30:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 20h 30m
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| FlixBus | 20h 20m | 1:05 PM | Rome | Anagnina Bus Station | 9:25 AM | Prague | ÚAN Florenc | Economy | $92 |
A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 9/13/2026 1:05:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/14/2026 9:25:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 20h 20m
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| FlixBus | 22h 10m | 9:00 PM | Rome | Tiburtina Bus Station | 7:10 PM | Prague | Na Knížecí Station | Economy | $93 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/13/2026 9:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/14/2026 7:10:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 22h 10m
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| FlixBus | 24h 25m | 1:05 PM | Rome | Anagnina Bus Station | 1:30 PM | Prague | Roztyly | Economy | $95 |
A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 9/13/2026 1:05:00 PM to Roztyly, Prague (Czech Republic) arriving at 9/14/2026 1:30:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 24h 25m
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Frequency of bus connections between Rome and Prague
Test cheapest views
Facts about the bus from Rome to Prague
Compare all providers like FlixBus that travel 40 times every day by bus from Rome to Prague in one click! Book your bus ticket from Rome to Prague starting from $77!
| Cheapest Bus | $77 |
| Fastest Bus | 19h 55m |
| Earliest Bus | 12:00 PM |
| Latest Bus | 11:35 PM |
| Daily Bus Routes | 40 Ø |
| Distance | 572.5 miles |
| Bus Companies | FlixBus |
Cheapest bus connections from Rome to Prague
Every day, 40 buses from 1 bus companies leave Rome for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/07/2026 and for the following days.
The cheapest time to travel from Rome to Prague
How to save money travelling from Rome to Prague
Book the ticket from Rome to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Prague, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Prague are also emptier.All bus stations and stops in Rome and Prague
In the map below, you can see where to find all bus stations in Rome and Prague.
Service and Comfort on the bus from Rome to Prague
FAQs about the Rome to Prague bus
How much does a Rome Prague bus trip cost?
How much could I save by comparing buses from Rome to Prague?
On average, how many connections are available from Rome to Prague each day?
How long does a bus journey from Rome to Prague take?
What time is the first bus from Rome to Prague?
What time is the last bus from Rome to Prague?
Which bus companies operate the Rome Prague route?
Is there a direct bus between Rome and Prague?
What can I take with me on the Rome to Prague bus route?
What equipment is available for the Rome Prague bus route?
Available seat classes which are offered on the bus route Rome to Prague
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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