Bus Rome to Siena - Compare all Companies

Compare all timetables for the bus from Rome to Siena

Here is a selection of the cheapest bus trips from the schedule from Rome to Siena from various bus operators like Itabus, MarinoBus or FlixBus for the next days.

today

$18

tomorrow

$13

Saturday

$12

Sunday

$23

Monday

$13

Tuesday

$11

Wednesday

$11

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	2:00 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Train Station	Premium Economy	$18	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/23/2026 2:00:00 PM to Train Station, Siena (Italy) arriving at 7/23/2026 4:50:00 PM. 50 Premium Economy ticket for $18 per person are available. Travel duration is 2h 50m
MarinoBus	3h 0m	1:50 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Train Station	Economy	$24	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 7/23/2026 1:50:00 PM to Train Station, Siena (Italy) arriving at 7/23/2026 4:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 3h 0m
Itabus	2h 49m	10:15 PM	Rome	Tiburtina Bus Station	1:04 AM	Siena	Train Station	Premium Economy	$30	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/23/2026 10:15:00 PM to Train Station, Siena (Italy) arriving at 7/24/2026 1:04:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 2h 49m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	11:00 AM	Rome	Tiburtina Bus Station	1:50 PM	Siena	Central Bus Station	Economy	$13	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/24/2026 11:00:00 AM to Central Bus Station, Siena (Italy) arriving at 7/24/2026 1:50:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	8:00 AM	Rome	Tiburtina Bus Station	10:50 AM	Siena	Train Station	Premium Economy	$20	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/24/2026 8:00:00 AM to Train Station, Siena (Italy) arriving at 7/24/2026 10:50:00 AM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	2:00 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Train Station	Premium Economy	$20	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/24/2026 2:00:00 PM to Train Station, Siena (Italy) arriving at 7/24/2026 4:50:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 2h 50m
MarinoBus	3h 0m	1:50 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Central Bus Station	Economy	$23	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 7/24/2026 1:50:00 PM to Central Bus Station, Siena (Italy) arriving at 7/24/2026 4:50:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 3h 0m
MarinoBus	3h 10m	5:35 AM	Rome	Tiburtina Bus Station	8:45 AM	Siena	Central Bus Station	Economy	$28	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 7/24/2026 5:35:00 AM to Central Bus Station, Siena (Italy) arriving at 7/24/2026 8:45:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 3h 10m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Busitalia Rail Service	2h 50m	6:00 AM	Rome	Tiburtina Bus Station	8:50 AM	Siena	Central Bus Station	Economy	$12	A Bus from Busitalia Rail Service goes from Tiburtina Bus Station, Rome (Italy) at 7/25/2026 6:00:00 AM to Central Bus Station, Siena (Italy) arriving at 7/25/2026 8:50:00 AM. 50 Economy ticket for $12 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	11:00 AM	Rome	Tiburtina Bus Station	1:50 PM	Siena	Piazza Antonio Gramsci	Economy	$13	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/25/2026 11:00:00 AM to Piazza Antonio Gramsci, Siena (Italy) arriving at 7/25/2026 1:50:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 50m
MarinoBus	3h 0m	1:50 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Train Station	Economy	$24	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 7/25/2026 1:50:00 PM to Train Station, Siena (Italy) arriving at 7/25/2026 4:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 3h 0m
Itabus	2h 50m	2:00 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Central Bus Station	Economy	$24	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/25/2026 2:00:00 PM to Central Bus Station, Siena (Italy) arriving at 7/25/2026 4:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 2h 50m
MarinoBus	3h 10m	5:35 AM	Rome	Tiburtina Bus Station	8:45 AM	Siena	Train Station	Economy	$34	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 7/25/2026 5:35:00 AM to Train Station, Siena (Italy) arriving at 7/25/2026 8:45:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 3h 10m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	8:00 AM	Rome	Tiburtina Bus Station	10:50 AM	Siena	Train Station	Premium Economy	$23	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/26/2026 8:00:00 AM to Train Station, Siena (Italy) arriving at 7/26/2026 10:50:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	11:00 AM	Rome	Tiburtina Bus Station	1:50 PM	Siena	Train Station	Premium Economy	$23	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/26/2026 11:00:00 AM to Train Station, Siena (Italy) arriving at 7/26/2026 1:50:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	2:00 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Train Station	Premium Economy	$23	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/26/2026 2:00:00 PM to Train Station, Siena (Italy) arriving at 7/26/2026 4:50:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 2h 50m
MarinoBus	3h 0m	1:50 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Piazza Antonio Gramsci	Economy	$27	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 7/26/2026 1:50:00 PM to Piazza Antonio Gramsci, Siena (Italy) arriving at 7/26/2026 4:50:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 3h 0m
MarinoBus	3h 10m	5:35 AM	Rome	Tiburtina Bus Station	8:45 AM	Siena	Piazza Antonio Gramsci	Economy	$32	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 7/26/2026 5:35:00 AM to Piazza Antonio Gramsci, Siena (Italy) arriving at 7/26/2026 8:45:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 3h 10m

Did you know that if you travel from Rome to Siena via Rome Fiumicino Airport, you can save more than $5? You can find the corresponding connections below.
- Terravision
  
  4h 0m
  
  0
  
  8:20 PM
  
  Rome
  Vatican City
  
  9:00 PM
  
  Rome Fiumicino Airport
  Rome Fiumicino Airport
  
  0
  
  Economy
  
  $7
  
  A Bus from Terravision goes from Vatican City, Rome (Italy) at 7/24/2026 8:20:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 7/24/2026 9:00:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 0h 40m
- Tiemme SpA
  
  3h 5m
  
  0
  
  9:15 PM
  
  Rome Fiumicino Airport
  Rome Fiumicino Airport
  
  12:20 AM
  
  Siena
  Piazza Antonio Gramsci
  
  0
  
  Economy
  
  $11
  
  A Bus from Tiemme SpA goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 7/24/2026 9:15:00 PM to Piazza Antonio Gramsci, Siena (Italy) arriving at 7/25/2026 12:20:00 AM. 50 Economy ticket for $11 per person are available. Travel duration is 3h 5m
Travel time is 1h 10m longer, but you will save $5

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	11:00 AM	Rome	Tiburtina Bus Station	1:50 PM	Siena	Central Bus Station	Economy	$13	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/27/2026 11:00:00 AM to Central Bus Station, Siena (Italy) arriving at 7/27/2026 1:50:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	2:00 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Central Bus Station	Economy	$13	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/27/2026 2:00:00 PM to Central Bus Station, Siena (Italy) arriving at 7/27/2026 4:50:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 50m
MarinoBus	3h 0m	1:50 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Train Station	Economy	$24	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 7/27/2026 1:50:00 PM to Train Station, Siena (Italy) arriving at 7/27/2026 4:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 3h 0m
MarinoBus	3h 10m	5:35 AM	Rome	Tiburtina Bus Station	8:45 AM	Siena	Central Bus Station	Economy	$29	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 7/27/2026 5:35:00 AM to Central Bus Station, Siena (Italy) arriving at 7/27/2026 8:45:00 AM. 50 Economy ticket for $29 per person are available. Travel duration is 3h 10m
Itabus	2h 50m	8:00 AM	Rome	Tiburtina Bus Station	10:50 AM	Siena	Central Bus Station	Economy	$30	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/27/2026 8:00:00 AM to Central Bus Station, Siena (Italy) arriving at 7/27/2026 10:50:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 2h 50m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	2h 45m	6:30 AM	Rome	Tiburtina Bus Station	9:15 AM	Siena	Train Station	Economy	$11	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/28/2026 6:30:00 AM to Train Station, Siena (Italy) arriving at 7/28/2026 9:15:00 AM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 45m
FlixBus	2h 39m	5:45 PM	Rome	Tiburtina Bus Station	8:24 PM	Siena	Train Station	Economy	$11	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/28/2026 5:45:00 PM to Train Station, Siena (Italy) arriving at 7/28/2026 8:24:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 39m
Itabus	2h 50m	11:00 AM	Rome	Tiburtina Bus Station	1:50 PM	Siena	Train Station	Premium Economy	$18	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/28/2026 11:00:00 AM to Train Station, Siena (Italy) arriving at 7/28/2026 1:50:00 PM. 50 Premium Economy ticket for $18 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	2:00 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Train Station	Premium Economy	$18	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/28/2026 2:00:00 PM to Train Station, Siena (Italy) arriving at 7/28/2026 4:50:00 PM. 50 Premium Economy ticket for $18 per person are available. Travel duration is 2h 50m
MarinoBus	3h 0m	1:50 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Train Station	Economy	$24	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 7/28/2026 1:50:00 PM to Train Station, Siena (Italy) arriving at 7/28/2026 4:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 3h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	11:00 AM	Rome	Tiburtina Bus Station	1:50 PM	Siena	Train Station	Premium Economy	$11	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/29/2026 11:00:00 AM to Train Station, Siena (Italy) arriving at 7/29/2026 1:50:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	2:00 PM	Rome	Tiburtina Bus Station	4:50 PM	Siena	Train Station	Premium Economy	$11	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/29/2026 2:00:00 PM to Train Station, Siena (Italy) arriving at 7/29/2026 4:50:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 2h 50m
FlixBus	2h 39m	5:45 PM	Rome	Tiburtina Bus Station	8:24 PM	Siena	Train Station	Economy	$11	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/29/2026 5:45:00 PM to Train Station, Siena (Italy) arriving at 7/29/2026 8:24:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 39m
FlixBus	2h 45m	7:10 PM	Rome	Tiburtina Bus Station	9:55 PM	Siena	Train Station	Economy	$11	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/29/2026 7:10:00 PM to Train Station, Siena (Italy) arriving at 7/29/2026 9:55:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 45m
Busitalia Fast	3h 0m	6:00 AM	Rome	Tiburtina Bus Station	9:00 AM	Siena	Piazza Antonio Gramsci	Economy	$13	A Bus from Busitalia Fast goes from Tiburtina Bus Station, Rome (Italy) at 7/29/2026 6:00:00 AM to Piazza Antonio Gramsci, Siena (Italy) arriving at 7/29/2026 9:00:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 3h 0m

Best Price Offer: The price for the cheapest bus from Rome to Siena is $9 on 7/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Rome and Siena

See here how frequent the connections between Rome and Siena are, during different times and days of the week.

Wednesday is the busiest day, with more than 41 daily buses from Rome to Siena. Thursday has instead the fewest connections, with only 5 daily coaches between Rome and Siena.

The busiest time of the day is the Afternoon, with 47 buses from Rome to Siena, while Night sees the fewest connections between Rome and Siena, with 13 offers.

Facts about the bus from Rome to Siena

Compare all providers like Itabus, MarinoBus and FlixBus that travel 16 times every day by bus from Rome to Siena in one click! Book your bus ticket from Rome to Siena starting from $9!

Cheapest Bus	$9
Fastest Bus	2h 39m
Earliest Bus	1:50 PM
Latest Bus	10:15 PM
Daily Bus Routes	16 Ø
Distance	114.5 miles
Bus Companies	Itabus, MarinoBus, FlixBus, Busitalia Rail Service and Busitalia Fast

Cheapest bus connections from Rome to Siena

Every day, 16 buses from 5 bus companies leave Rome for Siena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/23/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

$24

Friday 07/24

$10

Saturday 07/25

$12

Sunday 07/26

$26

Monday 07/27

$24

Tuesday 07/28

$24

Wednesday 07/29

$11

Thursday 07/30

$13

Friday 07/31

$11

Saturday 08/01

$14

Sunday 08/02

$23

Monday 08/03

$21

Tuesday 08/04

$14

Wednesday 08/05

$11

Thursday 08/06

$13

Friday 08/07

$22

Saturday 08/08

$12

Sunday 08/09

$11

Monday 08/10

$14

Tuesday 08/11

$12

Wednesday 08/12

$14

Thursday 08/13

$29

Friday 08/14

$30

Saturday 08/15

The cheapest time to travel from Rome to Siena

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Siena, for the next 30 days.

With a price starting from $10, Friday is the cheapest day for a bus from Rome to Siena. Thursday instead is the most expensive day with prices starting from $13.

Night is the cheapest day time for bus tickets from Rome to Siena, with $10. Morning is the most expensive time of the day with prices starting from $11.

How to save money travelling from Rome to Siena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Siena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Siena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Siena are also emptier.

All bus stations and stops in Rome and Siena

In the map below, you can see where to find all bus stations in Rome and Siena.

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Piazza Antonio Gramsci

Central Bus Station

Bus Stop

Viale Pietro Toselli 9

Colonna San Marco

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Siena? Compare all modes of transports from Rome to Siena.

Service and Comfort on the bus from Rome to Siena

Want to know which seat classes are available on the buses from Rome to Siena? Or which bus companies serve the route Rome to Siena? Below you will find answers to your questions.

FAQs about the Rome to Siena bus

How much does a Rome Siena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $9 and takes 2h 45m to reach Siena. Compare offers to save money!

How much could I save by comparing buses from Rome to Siena?

This route is offered by 5 companies with a range of ticket prices between $9 and $44. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Siena.

On average, how many connections are available from Rome to Siena each day?

Every day, the Rome to Siena bus route is served by approximately 16 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Siena take?

The fastest bus from Rome to Siena is offered by FlixBus and takes 2h 39m. Bus tickets for this connection cost $11. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Siena?

The earliest bus arriving in Siena from Rome starts at 1:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Siena?

The latest bus trip departing from Rome for Siena starts at 10:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Siena route?

When traveling by bus from Rome to Siena, passengers can travel with Itabus, MarinoBus and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Siena?

You can check all the direct connections between Rome and Siena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus, MarinoBus and FlixBus.

What can I take with me on the Rome to Siena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Siena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Siena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Siena on your planned travel date.

Available seat classes which are offered on the bus route Rome to Siena

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Rome and to Siena

Here’s an overview of the most popular bus routes to Rome and to Siena. Simply click on the connection of your choice, and you will find all the details about your bus route!