Bus Naples to Siena - Compare all Companies

Compare all timetables for the bus from Naples to Siena

Here is a selection of the cheapest bus trips from the schedule from Naples to Siena from various bus operators like Itabus or FlixBus for the next days.

today

$37

tomorrow

$18

Friday

$21

Saturday

$17

Sunday

$23

Monday

$17

Tuesday

$17

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Itabus	7h 19m	5:45 PM	Naples	Metropark Centrale	1:04 AM	Siena	Train Station		Premium Economy	$37	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/22/2026 5:45:00 PM to Train Station, Siena (Italy) arriving at 7/23/2026 1:04:00 AM. 50 Premium Economy ticket for $37 per person are available. Travel duration is 7h 19m
	Itabus	6h 59m	6:05 PM	Naples	Metropark Centrale	1:04 AM	Siena	Train Station		Premium Economy	$37	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/22/2026 6:05:00 PM to Train Station, Siena (Italy) arriving at 7/23/2026 1:04:00 AM. 50 Premium Economy ticket for $37 per person are available. Travel duration is 6h 59m

Did you know that if you travel from Naples to Siena via Rome, you can save more than $15? You can find the corresponding connections below.
- FlixBus
  
  6h 35m
  
  0
  
  7:15 AM
  
  Naples
  Metropark Centrale
  
  10:25 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $9
  
  A Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 7/24/2026 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/24/2026 10:25:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 3h 10m
- Itabus
  
  2h 50m
  
  0
  
  11:00 AM
  
  Rome
  Tiburtina Bus Station
  
  1:50 PM
  
  Siena
  Central Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/24/2026 11:00:00 AM to Central Bus Station, Siena (Italy) arriving at 7/24/2026 1:50:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 50m
Travel Time is 0h 24m shorter, and you will save $15

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 5m	4:45 AM	Naples	Metropark Centrale	10:50 AM	Siena	Train Station	Premium Economy	$18	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/23/2026 4:45:00 AM to Train Station, Siena (Italy) arriving at 7/23/2026 10:50:00 AM. 50 Premium Economy ticket for $18 per person are available. Travel duration is 6h 5m
Itabus	6h 5m	7:45 AM	Naples	Metropark Centrale	1:50 PM	Siena	Train Station	Premium Economy	$19	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/23/2026 7:45:00 AM to Train Station, Siena (Italy) arriving at 7/23/2026 1:50:00 PM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 6h 5m
Itabus	6h 5m	10:45 AM	Naples	Metropark Centrale	4:50 PM	Siena	Train Station	Economy	$22	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/23/2026 10:45:00 AM to Train Station, Siena (Italy) arriving at 7/23/2026 4:50:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 6h 5m
Itabus	7h 19m	5:45 PM	Naples	Metropark Centrale	1:04 AM	Siena	Train Station	Premium Economy	$22	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/23/2026 5:45:00 PM to Train Station, Siena (Italy) arriving at 7/24/2026 1:04:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 7h 19m
Itabus	6h 59m	6:05 PM	Naples	Metropark Centrale	1:04 AM	Siena	Train Station	Premium Economy	$22	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/23/2026 6:05:00 PM to Train Station, Siena (Italy) arriving at 7/24/2026 1:04:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 6h 59m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 35m	5:00 AM	Naples	Metropark Centrale	10:35 AM	Siena	Train Station	Economy	$21	A Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 7/24/2026 5:00:00 AM to Train Station, Siena (Italy) arriving at 7/24/2026 10:35:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 35m
FlixBus	6h 5m	8:15 AM	Naples	Metropark Centrale	2:20 PM	Siena	Train Station	Economy	$25	A Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 7/24/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 7/24/2026 2:20:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 6h 5m
FlixBus	6h 35m	2:40 AM	Naples	Metropark Centrale	9:15 AM	Siena	Train Station	Economy	$29	A Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 7/24/2026 2:40:00 AM to Train Station, Siena (Italy) arriving at 7/24/2026 9:15:00 AM. 50 Economy ticket for $29 per person are available. Travel duration is 6h 35m
FlixBus	6h 54m	1:30 PM	Naples	Metropark Centrale	8:24 PM	Siena	Train Station	Economy	$30	A Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 7/24/2026 1:30:00 PM to Train Station, Siena (Italy) arriving at 7/24/2026 8:24:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 6h 54m
FlixBus	6h 0m	9:00 AM	Naples	Metropark Centrale	3:00 PM	Siena	Train Station	Economy	$31	A Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 7/24/2026 9:00:00 AM to Train Station, Siena (Italy) arriving at 7/24/2026 3:00:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 6h 0m

Did you know that if you travel from Naples to Siena via Rome, you can save more than $2? You can find the corresponding connections below.
- Itabus
  
  6h 5m
  
  0
  
  7:45 AM
  
  Naples
  Metropark Centrale
  
  10:50 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $7
  
  A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/25/2026 7:45:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/25/2026 10:50:00 AM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 3h 5m
- Itabus
  
  2h 50m
  
  0
  
  11:00 AM
  
  Rome
  Tiburtina Bus Station
  
  1:50 PM
  
  Siena
  Central Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/25/2026 11:00:00 AM to Central Bus Station, Siena (Italy) arriving at 7/25/2026 1:50:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 50m
Travel time is 0h 30m longer, but you will save $2

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 5m	7:45 AM	Naples	Metropark Centrale	1:50 PM	Siena	Train Station	Premium Economy	$17	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/25/2026 7:45:00 AM to Train Station, Siena (Italy) arriving at 7/25/2026 1:50:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 6h 5m
FlixBus	5h 35m	5:00 AM	Naples	Metropark Centrale	10:35 AM	Siena	Train Station	Economy	$20	A Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 7/25/2026 5:00:00 AM to Train Station, Siena (Italy) arriving at 7/25/2026 10:35:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 5h 35m
Itabus	6h 5m	10:45 AM	Naples	Metropark Centrale	4:50 PM	Siena	Train Station	Premium Economy	$23	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/25/2026 10:45:00 AM to Train Station, Siena (Italy) arriving at 7/25/2026 4:50:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 6h 5m
FlixBus	6h 5m	8:15 AM	Naples	Metropark Centrale	2:20 PM	Siena	Train Station	Economy	$27	A Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 7/25/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 7/25/2026 2:20:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 6h 5m
FlixBus	6h 0m	6:40 PM	Naples	Metropark Centrale	12:40 AM	Siena	Train Station	Economy	$29	A Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 7/25/2026 6:40:00 PM to Train Station, Siena (Italy) arriving at 7/26/2026 12:40:00 AM. 50 Economy ticket for $29 per person are available. Travel duration is 6h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 35m	5:00 AM	Naples	Metropark Centrale	10:35 AM	Siena	Train Station	Economy	$23	A Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 7/26/2026 5:00:00 AM to Train Station, Siena (Italy) arriving at 7/26/2026 10:35:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 5h 35m
Itabus	6h 5m	4:45 AM	Naples	Metropark Centrale	10:50 AM	Siena	Train Station	Premium Economy	$23	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/26/2026 4:45:00 AM to Train Station, Siena (Italy) arriving at 7/26/2026 10:50:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 6h 5m
Itabus	6h 5m	7:45 AM	Naples	Metropark Centrale	1:50 PM	Siena	Train Station	Premium Economy	$23	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/26/2026 7:45:00 AM to Train Station, Siena (Italy) arriving at 7/26/2026 1:50:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 6h 5m
Itabus	6h 5m	10:45 AM	Naples	Metropark Centrale	4:50 PM	Siena	Train Station	Premium Economy	$23	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/26/2026 10:45:00 AM to Train Station, Siena (Italy) arriving at 7/26/2026 4:50:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 6h 5m
FlixBus	6h 5m	8:15 AM	Naples	Metropark Centrale	2:20 PM	Siena	Train Station	Economy	$29	A Bus from FlixBus goes from Metropark Centrale, Naples (Italy) at 7/26/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 7/26/2026 2:20:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 6h 5m

Did you know that if you travel from Naples to Siena via Rome, you can save more than $4? You can find the corresponding connections below.
- Itabus
  
  6h 5m
  
  0
  
  7:45 AM
  
  Naples
  Metropark Centrale
  
  10:50 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $7
  
  A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/25/2026 7:45:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/25/2026 10:50:00 AM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 3h 5m
- Itabus
  
  2h 50m
  
  0
  
  11:00 AM
  
  Rome
  Tiburtina Bus Station
  
  1:50 PM
  
  Siena
  Central Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/25/2026 11:00:00 AM to Central Bus Station, Siena (Italy) arriving at 7/25/2026 1:50:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 50m
Travel time is 0h 30m longer, but you will save $4

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 5m	7:45 AM	Naples	Metropark Centrale	1:50 PM	Siena	Train Station	Premium Economy	$17	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/27/2026 7:45:00 AM to Train Station, Siena (Italy) arriving at 7/27/2026 1:50:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 6h 5m
Itabus	6h 5m	10:45 AM	Naples	Metropark Centrale	4:50 PM	Siena	Train Station	Premium Economy	$17	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/27/2026 10:45:00 AM to Train Station, Siena (Italy) arriving at 7/27/2026 4:50:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 6h 5m
Itabus	6h 5m	4:45 AM	Naples	Metropark Centrale	10:50 AM	Siena	Train Station	Premium Economy	$46	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/27/2026 4:45:00 AM to Train Station, Siena (Italy) arriving at 7/27/2026 10:50:00 AM. 50 Premium Economy ticket for $46 per person are available. Travel duration is 6h 5m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 5m	7:45 AM	Naples	Metropark Centrale	1:50 PM	Siena	Train Station	Premium Economy	$17	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/28/2026 7:45:00 AM to Train Station, Siena (Italy) arriving at 7/28/2026 1:50:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 6h 5m
Itabus	6h 5m	10:45 AM	Naples	Metropark Centrale	4:50 PM	Siena	Train Station	Premium Economy	$17	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/28/2026 10:45:00 AM to Train Station, Siena (Italy) arriving at 7/28/2026 4:50:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 6h 5m
Itabus	6h 5m	4:45 AM	Naples	Metropark Centrale	10:50 AM	Siena	Train Station	Premium Economy	$34	A Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 7/28/2026 4:45:00 AM to Train Station, Siena (Italy) arriving at 7/28/2026 10:50:00 AM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 6h 5m

Best Price Offer: The price for the cheapest bus from Naples to Siena is $17 on 7/25/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Naples and Siena

See here how frequent the connections between Naples and Siena are, during different times and days of the week.

Sunday is the busiest day, with more than 44 daily buses from Naples to Siena. Wednesday has instead the fewest connections, with only 2 daily coaches between Naples and Siena.

The busiest time of the day is the Morning, with 57 buses from Naples to Siena, while Afternoon sees the fewest connections between Naples and Siena, with 21 offers.

Facts about the bus from Naples to Siena

Compare all providers like Itabus and FlixBus that travel 17 times every day by bus from Naples to Siena in one click! Book your bus ticket from Naples to Siena starting from $17!

Cheapest Bus	$17
Fastest Bus	5h 35m
Earliest Bus	5:45 PM
Latest Bus	10:45 AM
Daily Bus Routes	17 Ø
Distance	227.5 miles
Bus Companies	Itabus and FlixBus

Cheapest bus connections from Naples to Siena

Every day, 17 buses from 2 bus companies leave Naples for Siena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

$19

Thursday 07/23

$18

Friday 07/24

$21

Saturday 07/25

$17

Sunday 07/26

$23

Monday 07/27

$19

Tuesday 07/28

$19

Wednesday 07/29

$24

Thursday 07/30

$21

Friday 07/31

$18

Saturday 08/01

$26

Sunday 08/02

$23

Monday 08/03

$23

Tuesday 08/04

$31

Wednesday 08/05

$18

Thursday 08/06

$21

Friday 08/07

$43

Saturday 08/08

$32

Sunday 08/09

$29

Monday 08/10

$21

Tuesday 08/11

$19

Wednesday 08/12

$17

Thursday 08/13

Friday 08/14

Saturday 08/15

The cheapest time to travel from Naples to Siena

See here on which day and which time of the day you can find the cheapest bus ticket from Naples to Siena, for the next 30 days.

With a price starting from $17, Monday is the cheapest day for a bus from Naples to Siena. Sunday instead is the most expensive day with prices starting from $23.

Morning is the cheapest day time for bus tickets from Naples to Siena, with $17. Afternoon is the most expensive time of the day with prices starting from $22.

How to save money travelling from Naples to Siena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Naples to Siena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Naples to Siena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Naples to Siena are also emptier.

All bus stations and stops in Naples and Siena

In the map below, you can see where to find all bus stations in Naples and Siena.

Afragola Bus Station

Via Arena

Metropark Centrale

Corso Arnaldo Lucci

Port

Varco Immacolatella

Ferry Terminal Beverello

Piazza Antonio Gramsci

Central Bus Station

Bus Stop

Viale Pietro Toselli 9

Colonna San Marco

Service and Comfort on the bus from Naples to Siena

Want to know which seat classes are available on the buses from Naples to Siena? Or which bus companies serve the route Naples to Siena? Below you will find answers to your questions.

FAQs about the Naples to Siena bus

How much does a Naples Siena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $17 and takes 6h 5m to reach Siena. Compare offers to save money!

How much could I save by comparing buses from Naples to Siena?

This route is offered by 2 companies with a range of ticket prices between $17 and $93. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Siena.

On average, how many connections are available from Naples to Siena each day?

Every day, the Naples to Siena bus route is served by approximately 17 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Naples to Siena take?

The fastest bus from Naples to Siena is offered by FlixBus and takes 5h 35m. Bus tickets for this connection cost $21. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Naples to Siena?

The earliest bus arriving in Siena from Naples starts at 5:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Naples to Siena?

The latest bus trip departing from Naples for Siena starts at 10:45 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Naples Siena route?

When traveling by bus from Naples to Siena, passengers can travel with Itabus and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Naples and Siena?

You can check all the direct connections between Naples and Siena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus and FlixBus.

What can I take with me on the Naples to Siena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Naples Siena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Naples Siena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Naples to Siena on your planned travel date.

Available seat classes which are offered on the bus route Naples to Siena

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Naples and to Siena

Here’s an overview of the most popular bus routes to Naples and to Siena. Simply click on the connection of your choice, and you will find all the details about your bus route!