Which bus from Madison, WI to St. Louis, MO is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $54
Search for your destination Millions of deals worldwide
Compare results Save up to 70%
Find the right bus for you Easy and transparent

Compare all timetables for the bus from Madison, WI to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Madison, WI to St. Louis, MO from various bus operators like FlixBus or Greyhound US for the next days.

today
tomorrow
Monday
Tuesday
$72
Wednesday
$66
Thursday
Friday

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 16h 30m 6:45 AM Madison, WI University Wisconsin-Madison 11:15 PM St. Louis, MO Gateway Station  Economy $72
FlixBus 16h 15m 7:00 AM Madison, WI W Transfer Point 11:15 PM St. Louis, MO Gateway Station  Economy $73
FlixBus 16h 40m 1:45 PM Madison, WI W Transfer Point 6:25 AM St. Louis, MO Gateway Station  Economy $74
Greyhound US 12h 25m 6:00 PM Madison, WI University Wisconsin-Madison 6:25 AM St. Louis, MO Gateway Station  Economy $74
  • Did you know that if you travel from Madison, WI to St. Louis, MO via Chicago, you can save more than $10? You can find the corresponding connections below.
    • Greyhound US
      12h 25m
      0
      6:00 PM
      Madison, WI
      Chazen Museum
      9:15 PM
      Chicago
      Downtown Bus Station
      0
      Greyhound US
      Economy
      $24
      • Waiting Time 3h 25m
    • FlixBus
      5h 45m
      0
      12:40 AM
      Chicago
      95th Red Line Station
      6:25 AM
      St. Louis, MO
      Gateway Station
      0
      FlixBus
      Economy
      $38
    Travel time is the same as the direct connection, but you will save $10

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 16h 30m 6:45 AM Madison, WI University Wisconsin-Madison 11:15 PM St. Louis, MO Gateway Station  Economy $66
FlixBus 16h 15m 7:00 AM Madison, WI W Transfer Point 11:15 PM St. Louis, MO Gateway Station  Economy $66
FlixBus 16h 40m 1:45 PM Madison, WI W Transfer Point 6:25 AM St. Louis, MO Gateway Station  Economy $66
Greyhound US 12h 25m 6:00 PM Madison, WI University Wisconsin-Madison 6:25 AM St. Louis, MO Gateway Station  Economy $66

Best Price Offer: The price for the cheapest bus from Madison, WI to St. Louis, MO is $54 on 8/11/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Madison, WI and St. Louis, MO

See here how frequent the connections between Madison, WI and St. Louis, MO are, during different times and days of the week.
Tuesday is the busiest day, with more than 4 daily buses from Madison, WI to St. Louis, MO. Tuesday has instead the fewest connections, with only 4 daily coaches between Madison, WI and St. Louis, MO.
The busiest time of the day is the Morning, with 4 buses from Madison, WI to St. Louis, MO, while Afternoon sees the fewest connections between Madison, WI and St. Louis, MO, with 2 offers.

Facts about the bus from Madison, WI to St. Louis, MO

Compare all providers like FlixBus and Greyhound US that travel 4 times every day by bus from Madison, WI to St. Louis, MO in one click! Book your bus ticket from Madison, WI to St. Louis, MO starting from $54!

Cheapest Bus $54
Fastest Bus 12h 25m
Earliest Bus 6:45 AM
Latest Bus 6:00 PM
Daily Bus Routes 4 Ø
Distance 310.6 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Madison, WI to St. Louis, MO

Every day, 4 buses from 2 bus companies leave Madison, WI for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/19
Monday 07/20
Tuesday 07/21
Wednesday 07/22
Thursday 07/23
Friday 07/24
Saturday 07/25
Sunday 07/26
Monday 07/27
Tuesday 07/28
$72
Wednesday 07/29
$66
Thursday 07/30
Friday 07/31
Saturday 08/01
Sunday 08/02
Monday 08/03
$62
Tuesday 08/04
Wednesday 08/05
Thursday 08/06
Friday 08/07
Saturday 08/08
$55
Sunday 08/09
$61
Monday 08/10
Tuesday 08/11
$54
Wednesday 08/12
$58
Thursday 08/13
Friday 08/14
Saturday 08/15

The cheapest time to travel from Madison, WI to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Madison, WI to St. Louis, MO, for the next 30 days.
With a price starting from $54, Tuesday is the cheapest day for a bus from Madison, WI to St. Louis, MO. Wednesday instead is the most expensive day with prices starting from $58.
Morning is the cheapest day time for bus tickets from Madison, WI to St. Louis, MO, with $66. Evening is the most expensive time of the day with prices starting from $66.

How to save money travelling from Madison, WI to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madison, WI to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madison, WI to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madison, WI to St. Louis, MO are also emptier.

All bus stations and stops in Madison, WI and St. Louis, MO

In the map below, you can see where to find all bus stations in Madison, WI and St. Louis, MO.

Service and Comfort on the bus from Madison, WI to St. Louis, MO

Want to know which seat classes are available on the buses from Madison, WI to St. Louis, MO? Or which bus companies serve the route Madison, WI to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Madison, WI to St. Louis, MO bus

How much does a Madison, WI St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $54 and takes 16h 30m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Madison, WI to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $54 and $74. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Madison, WI to St. Louis, MO each day?

Every day, the Madison, WI to St. Louis, MO bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Madison, WI to St. Louis, MO take?

The fastest bus from Madison, WI to St. Louis, MO is offered by Greyhound US and takes 12h 25m. Bus tickets for this connection cost $74. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Madison, WI to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Madison, WI starts at 6:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Madison, WI to St. Louis, MO?

The latest bus trip departing from Madison, WI for St. Louis, MO starts at 6:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Madison, WI St. Louis, MO route?

When traveling by bus from Madison, WI to St. Louis, MO, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Madison, WI and St. Louis, MO?

You can check all the direct connections between Madison, WI and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Madison, WI to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Madison, WI St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Madison, WI St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madison, WI to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Madison, WI to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madison, WI and to St. Louis, MO

Here’s an overview of the most popular bus routes to Madison, WI and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
Johnson Creek, WI to Madison, WI bus Johnson Creek, WI to Madison, WI bus
Buses Toledo, OH to Madison, WI Buses Toledo, OH to Madison, WI
Bus to Madison, WI from Baraboo,WI Bus to Madison, WI from Baraboo,WI
From Bloomington, MN to Madison, WI bus From Bloomington, MN to Madison, WI bus
Bus from Mansfield, OH to St. Louis, MO Bus from Mansfield, OH to St. Louis, MO
From Joplin, MO to St. Louis, MO bus From Joplin, MO to St. Louis, MO bus
Buses Rocky Mount, NC - St. Louis, MO Buses Rocky Mount, NC - St. Louis, MO
Buses to St. Louis, MO from Greensboro, NC Buses to St. Louis, MO from Greensboro, NC
Popular Airport Shuttles to Madison, WI and to St. Louis, MO
CheckMyBus › Buses in USA › Bus to Madison, WI › Bus to St. Louis, MO

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.