Bus Columbia, MO to St. Louis, MO - Compare all Companies

Compare all timetables for the bus from Columbia, MO to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Columbia, MO to St. Louis, MO from various bus operators like Greyhound US for the next days.

today

tomorrow

$25

Monday

Tuesday

$19

Wednesday

Thursday

$24

Friday

$25

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	3h 35m	8:30 AM	Columbia, MO	Bus Stop	12:05 PM	St. Louis, MO	Gateway Station	Economy	$25	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 7/26/2026 8:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/26/2026 12:05:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 3h 35m
Greyhound US	2h 50m	8:05 PM	Columbia, MO	Bus Stop	10:55 PM	St. Louis, MO	Gateway Station	Economy	$25	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 7/26/2026 8:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/26/2026 10:55:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 2h 50m
Greyhound US	3h 5m	9:00 AM	Columbia, MO	Red Thread	12:05 PM	St. Louis, MO	Gateway Station	Economy	$25	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/26/2026 9:00:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/26/2026 12:05:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 3h 5m
Greyhound US	2h 20m	8:35 PM	Columbia, MO	Red Thread	10:55 PM	St. Louis, MO	Gateway Station	Economy	$25	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/26/2026 8:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/26/2026 10:55:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 2h 20m
Greyhound US	2h 15m	10:40 AM	Columbia, MO	Red Thread	12:55 PM	St. Louis, MO	Gateway Station	Economy	$35	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/26/2026 10:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/26/2026 12:55:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 2h 15m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	2h 50m	8:05 PM	Columbia, MO	Bus Stop	10:55 PM	St. Louis, MO	Gateway Station	Economy	$19	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 7/28/2026 8:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 10:55:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 2h 50m
Greyhound US	2h 20m	8:35 PM	Columbia, MO	Red Thread	10:55 PM	St. Louis, MO	Gateway Station	Economy	$19	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/28/2026 8:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 10:55:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 2h 20m
Greyhound US	3h 35m	8:30 AM	Columbia, MO	Bus Stop	12:05 PM	St. Louis, MO	Gateway Station	Economy	$22	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 7/28/2026 8:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 12:05:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 3h 35m
Greyhound US	3h 5m	9:00 AM	Columbia, MO	Red Thread	12:05 PM	St. Louis, MO	Gateway Station	Economy	$22	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/28/2026 9:00:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 12:05:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 3h 5m
Greyhound US	2h 15m	10:40 AM	Columbia, MO	Red Thread	12:55 PM	St. Louis, MO	Gateway Station	Economy	$24	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/28/2026 10:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 12:55:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 2h 15m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	2h 50m	8:05 PM	Columbia, MO	Bus Stop	10:55 PM	St. Louis, MO	Gateway Station	Economy	$24	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 7/30/2026 8:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/30/2026 10:55:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 2h 50m
Greyhound US	2h 15m	10:40 AM	Columbia, MO	Red Thread	12:55 PM	St. Louis, MO	Gateway Station	Economy	$24	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/30/2026 10:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/30/2026 12:55:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 2h 15m
Greyhound US	2h 20m	8:35 PM	Columbia, MO	Red Thread	10:55 PM	St. Louis, MO	Gateway Station	Economy	$24	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/30/2026 8:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/30/2026 10:55:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 2h 20m
Greyhound US	3h 35m	8:30 AM	Columbia, MO	Bus Stop	12:05 PM	St. Louis, MO	Gateway Station	Economy	$27	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 7/30/2026 8:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/30/2026 12:05:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 3h 35m
Greyhound US	3h 5m	9:00 AM	Columbia, MO	Red Thread	12:05 PM	St. Louis, MO	Gateway Station	Economy	$27	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/30/2026 9:00:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/30/2026 12:05:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 3h 5m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	3h 35m	8:30 AM	Columbia, MO	Bus Stop	12:05 PM	St. Louis, MO	Gateway Station	Economy	$25	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 7/31/2026 8:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/31/2026 12:05:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 3h 35m
Greyhound US	2h 50m	8:05 PM	Columbia, MO	Bus Stop	10:55 PM	St. Louis, MO	Gateway Station	Economy	$25	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 7/31/2026 8:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/31/2026 10:55:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 2h 50m
Greyhound US	3h 5m	9:00 AM	Columbia, MO	Red Thread	12:05 PM	St. Louis, MO	Gateway Station	Economy	$25	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/31/2026 9:00:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/31/2026 12:05:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 3h 5m
Greyhound US	2h 15m	10:40 AM	Columbia, MO	Red Thread	12:55 PM	St. Louis, MO	Gateway Station	Economy	$25	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/31/2026 10:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/31/2026 12:55:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 2h 15m
Greyhound US	2h 20m	8:35 PM	Columbia, MO	Red Thread	10:55 PM	St. Louis, MO	Gateway Station	Economy	$25	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 7/31/2026 8:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/31/2026 10:55:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 2h 20m

Best Price Offer: The price for the cheapest bus from Columbia, MO to St. Louis, MO is $19 on 7/28/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Columbia, MO and St. Louis, MO

See here how frequent the connections between Columbia, MO and St. Louis, MO are, during different times and days of the week.

Tuesday is the busiest day, with more than 10 daily buses from Columbia, MO to St. Louis, MO. Sunday has instead the fewest connections, with only 5 daily coaches between Columbia, MO and St. Louis, MO.

The busiest time of the day is the Morning, with 15 buses from Columbia, MO to St. Louis, MO, while Evening sees the fewest connections between Columbia, MO and St. Louis, MO, with 10 offers.

Facts about the bus from Columbia, MO to St. Louis, MO

Compare all providers like Greyhound US that travel 6 times every day by bus from Columbia, MO to St. Louis, MO in one click! Book your bus ticket from Columbia, MO to St. Louis, MO starting from $19!

Cheapest Bus	$19
Fastest Bus	2h 15m
Earliest Bus	8:30 AM
Latest Bus	8:35 PM
Daily Bus Routes	6 Ø
Distance	116.6 miles
Bus Companies	Greyhound US

Cheapest bus connections from Columbia, MO to St. Louis, MO

Every day, 6 buses from 1 bus companies leave Columbia, MO for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

Friday 07/24

Saturday 07/25

Sunday 07/26

$25

Monday 07/27

Tuesday 07/28

$19

Wednesday 07/29

$23

Thursday 07/30

$24

Friday 07/31

Saturday 08/01

$22

Sunday 08/02

$29

Monday 08/03

$22

Tuesday 08/04

$23

Wednesday 08/05

Thursday 08/06

$23

Friday 08/07

Saturday 08/08

$24

Sunday 08/09

$25

Monday 08/10

$19

Tuesday 08/11

$23

Wednesday 08/12

$19

Thursday 08/13

Friday 08/14

Saturday 08/15

The cheapest time to travel from Columbia, MO to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Columbia, MO to St. Louis, MO, for the next 30 days.

With a price starting from $19, Tuesday is the cheapest day for a bus from Columbia, MO to St. Louis, MO. Sunday instead is the most expensive day with prices starting from $25.

Evening is the cheapest day time for bus tickets from Columbia, MO to St. Louis, MO, with $19. Morning is the most expensive time of the day with prices starting from $22.

How to save money travelling from Columbia, MO to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Columbia, MO to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Columbia, MO to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Columbia, MO to St. Louis, MO are also emptier.

All bus stations and stops in Columbia, MO and St. Louis, MO

In the map below, you can see where to find all bus stations in Columbia, MO and St. Louis, MO.

Bus Stop

N 10th St 198

Red Thread

Highway 40 W 6401

University

Fellows Pl 1301-1349

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Service and Comfort on the bus from Columbia, MO to St. Louis, MO

Want to know which seat classes are available on the buses from Columbia, MO to St. Louis, MO? Or which bus companies serve the route Columbia, MO to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Columbia, MO to St. Louis, MO bus

How much does a Columbia, MO St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $19 and takes 2h 50m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Columbia, MO to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $19 and $35. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Columbia, MO to St. Louis, MO each day?

Every day, the Columbia, MO to St. Louis, MO bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Columbia, MO to St. Louis, MO take?

The fastest bus from Columbia, MO to St. Louis, MO is offered by Greyhound US and takes 2h 15m. Bus tickets for this connection cost $35. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Columbia, MO to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Columbia, MO starts at 8:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Columbia, MO to St. Louis, MO?

The latest bus trip departing from Columbia, MO for St. Louis, MO starts at 8:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Columbia, MO St. Louis, MO route?

When traveling by bus from Columbia, MO to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Columbia, MO and St. Louis, MO?

You can check all the direct connections between Columbia, MO and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Columbia, MO to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Columbia, MO St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Columbia, MO St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Columbia, MO to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Columbia, MO to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Columbia, MO and to St. Louis, MO

Here’s an overview of the most popular bus routes to Columbia, MO and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!