Bus from Milan to Messina from $22

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Compare all timetables for the bus from Milan to Messina

Here is a selection of the cheapest bus trips from the schedule from Milan to Messina from various bus operators like FlixBus, Itabus or Autoservizi Salemi for the next days.
today
$45
tomorrow
$46
Wednesday
$42
Thursday
$42
Friday
Saturday
Sunday
$42

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 19h 20m 6:30 PM Milan San Donato Bus Station 1:50 PM Messina Piazza della Repubblica  Economy $45
FlixBus 20h 5m 5:45 PM Milan Lampugnano Bus Station 1:50 PM Messina Piazza della Repubblica  Economy $45
FlixBus 20h 25m 2:45 PM Milan San Donato Bus Station 11:10 AM Messina Piazza della Repubblica  Economy $56
FlixBus 19h 55m 3:15 PM Milan Lampugnano Bus Station 11:10 AM Messina Piazza della Repubblica  Economy $57
FlixBus 21h 20m 8:35 PM Milan Lampugnano Bus Station 5:55 PM Messina Piazza della Repubblica  Economy $59
  • Did you know that if you travel from Milan to Messina via Rome, you can save more than $9? You can find the corresponding connections below.
    • FlixBus
      19h 15m
      0
      10:30 AM
      Milan
      Lampugnano Bus Station
      6:45 PM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $8
      • Waiting Time 0h 45m
    • Itabus
      10h 15m
      0
      7:30 PM
      Rome
      Tiburtina Bus Station
      5:45 AM
      Messina
      Piazza della Repubblica
      0
      Itabus
      Economy
      $28
    Travel Time is 0h 5m shorter, and you will save $9

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 5m 5:45 PM Milan Lampugnano Bus Station 1:50 PM Messina Piazza della Repubblica  Economy $46
FlixBus 19h 20m 6:30 PM Milan San Donato Bus Station 1:50 PM Messina Piazza della Repubblica  Economy $46
Itabus 19h 5m 10:40 AM Milan Lampugnano Bus Station 5:45 AM Messina Central Station  Premium Economy $73
Itabus 22h 50m 8:00 AM Milan San Donato Bus Station 6:50 AM Messina Piazza della Repubblica  Premium Economy $80
Autoservizi Salemi 17h 55m 10:45 AM Milan San Donato Bus Station 4:40 AM Messina Piazza della Repubblica  Economy $101
  • Did you know that if you travel from Milan to Messina via Rome, you can save more than $15? You can find the corresponding connections below.
    • FlixBus
      18h 35m
      0
      1:10 AM
      Milan
      San Donato Bus Station
      8:40 AM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $8
      • Waiting Time 0h 20m
    • Itabus
      10h 45m
      0
      9:00 AM
      Rome
      Tiburtina Bus Station
      7:45 PM
      Messina
      Central Station
      0
      Itabus
      Premium Economy
      $23
    Travel time is 0h 40m longer, but you will save $15

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 15m 1:05 PM Milan Lampugnano Bus Station 6:20 AM Messina Piazza della Repubblica  Economy $42
FlixBus 20h 5m 5:45 PM Milan Lampugnano Bus Station 1:50 PM Messina Piazza della Repubblica  Economy $47
FlixBus 19h 20m 6:30 PM Milan San Donato Bus Station 1:50 PM Messina Piazza della Repubblica  Economy $47
Itabus 19h 55m 11:50 PM Milan Lampugnano Bus Station 7:45 PM Messina Piazza della Repubblica  Economy $66
Itabus 19h 5m 10:40 AM Milan Lampugnano Bus Station 5:45 AM Messina Piazza della Repubblica  Economy $83
  • Did you know that if you travel from Milan to Messina via Rome, you can save more than $11? You can find the corresponding connections below.
    • FlixBus
      18h 35m
      0
      1:10 AM
      Milan
      San Donato Bus Station
      8:40 AM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $8
      • Waiting Time 0h 20m
    • Itabus
      10h 45m
      0
      9:00 AM
      Rome
      Tiburtina Bus Station
      7:45 PM
      Messina
      Central Station
      0
      Itabus
      Premium Economy
      $23
    Travel time is 1h 20m longer, but you will save $11

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 15m 1:05 PM Milan Lampugnano Bus Station 6:20 AM Messina Piazza della Repubblica  Economy $42
FlixBus 20h 5m 5:45 PM Milan Lampugnano Bus Station 1:50 PM Messina Piazza della Repubblica  Economy $49
FlixBus 19h 20m 6:30 PM Milan San Donato Bus Station 1:50 PM Messina Piazza della Repubblica  Economy $49
Itabus 19h 20m 11:50 PM Milan Lampugnano Bus Station 7:10 PM Messina Piazza della Repubblica  Economy $66
Itabus 19h 5m 10:40 AM Milan Lampugnano Bus Station 5:45 AM Messina Piazza della Repubblica  Economy $83
  • Did you know that if you travel from Milan to Messina via Rome, you can save more than $11? You can find the corresponding connections below.
    • FlixBus
      18h 35m
      0
      1:10 AM
      Milan
      San Donato Bus Station
      8:40 AM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $8
      • Waiting Time 0h 20m
    • Itabus
      10h 45m
      0
      9:00 AM
      Rome
      Tiburtina Bus Station
      7:45 PM
      Messina
      Central Station
      0
      Itabus
      Premium Economy
      $23
    Travel time is 1h 20m longer, but you will save $11

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 20h 10m 8:00 AM Milan San Donato Bus Station 4:10 AM Messina Central Station  Premium Economy $42
Itabus 22h 50m 8:00 AM Milan San Donato Bus Station 6:50 AM Messina Central Station  Premium Economy $44
Itabus 19h 45m 10:00 AM Milan San Donato Bus Station 5:45 AM Messina Central Station  Premium Economy $44
FlixBus 17h 15m 1:05 PM Milan Lampugnano Bus Station 6:20 AM Messina Piazza della Repubblica  Economy $50
FlixBus 20h 5m 5:45 PM Milan Lampugnano Bus Station 1:50 PM Messina Piazza della Repubblica  Economy $60
  • Did you know that if you travel from Milan to Messina via Rome, you can save more than $19? You can find the corresponding connections below.
    • FlixBus
      25h 15m
      0
      5:15 AM
      Milan
      Lampugnano Bus Station
      1:50 PM
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      $8
      • Waiting Time 7h 10m
    • FlixBus
      9h 30m
      0
      9:00 PM
      Rome
      Tiburtina Bus Station
      6:30 AM
      Messina
      Piazza della Repubblica
      0
      FlixBus
      Economy
      $15
    Travel time is 8h 0m longer, but you will save $19

Frequency of bus connections between Milan and Messina

See here how frequent the connections between Milan and Messina are, during different times and days of the week.
Tuesday is the busiest day, with more than 22 daily buses from Milan to Messina. Monday has instead the fewest connections, with only 8 daily coaches between Milan and Messina.
The busiest time of the day is the Evening, with 26 buses from Milan to Messina, while Night sees the fewest connections between Milan and Messina, with 8 offers.

Test cheapest views

The cheapest bus for the 9/26/2026 costs just $22, from FlixBus

Facts about the bus from Milan to Messina

Compare all providers like FlixBus, Itabus and Autoservizi Salemi that travel 14 times every day by bus from Milan to Messina in one click! Book your bus ticket from Milan to Messina starting from $22!

Cheapest Bus $22
Fastest Bus 17h 15m
Earliest Bus 2:45 PM
Latest Bus 11:20 PM
Daily Bus Routes 14 Ø
Distance 599.7 miles
Bus Companies FlixBus, Itabus and Autoservizi Salemi

Cheapest bus connections from Milan to Messina

Every day, 14 buses from 3 bus companies leave Milan for Messina: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/07/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 09/06
Monday 09/07
$41
Tuesday 09/08
$92
Wednesday 09/09
$64
Thursday 09/10
$79
Friday 09/11
$48
Saturday 09/12
$42
Sunday 09/13
$79
Monday 09/14
$46
Tuesday 09/15
$40
Wednesday 09/16
$74
Thursday 09/17
$38
Friday 09/18
$41
Saturday 09/19
$32
Sunday 09/20
$55
Monday 09/21
$53
Tuesday 09/22
$42
Wednesday 09/23
$38
Thursday 09/24
Friday 09/25
$41
Saturday 09/26
$22
Sunday 09/27
$55
Monday 09/28
$38
Tuesday 09/29
Wednesday 09/30
Thursday 10/01
$38
Friday 10/02
Saturday 10/03

The cheapest time to travel from Milan to Messina

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Messina, for the next 30 days.
With a price starting from $38, Monday is the cheapest day for a bus from Milan to Messina. Sunday instead is the most expensive day with prices starting from $42.
Night is the cheapest day time for bus tickets from Milan to Messina, with $22. Evening is the most expensive time of the day with prices starting from $45.

How to save money travelling from Milan to Messina

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Messina in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Messina, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Messina are also emptier.

All bus stations and stops in Milan and Messina

In the map below, you can see where to find all bus stations in Milan and Messina.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Messina? Compare all modes of transports from Milan to Messina.

Service and Comfort on the bus from Milan to Messina

Want to know which seat classes are available on the buses from Milan to Messina? Or which bus companies serve the route Milan to Messina? Below you will find answers to your questions.

FAQs about the Milan to Messina bus

How much does a Milan Messina bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $22 and takes 17h 15m to reach Messina. Compare offers to save money!

How much could I save by comparing buses from Milan to Messina?

This route is offered by 3 companies with a range of ticket prices between $22 and $211. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Messina.

On average, how many connections are available from Milan to Messina each day?

Every day, the Milan to Messina bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milan to Messina take?

The fastest bus from Milan to Messina is offered by FlixBus and takes 17h 15m. Bus tickets for this connection cost $48. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milan to Messina?

The earliest bus arriving in Messina from Milan starts at 2:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milan to Messina?

The latest bus trip departing from Milan for Messina starts at 11:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milan Messina route?

When traveling by bus from Milan to Messina, passengers can travel with FlixBus, Itabus and Autoservizi Salemi. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milan and Messina?

You can check all the direct connections between Milan and Messina by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and Autoservizi Salemi.

What can I take with me on the Milan to Messina bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milan Messina bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Messina bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Messina on your planned travel date.

Available seat classes which are offered on the bus route Milan to Messina

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Milan and to Messina

Here’s an overview of the most popular bus routes to Milan and to Messina. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Milan from Scanzano Jonico Bus to Milan from Scanzano Jonico
From Peschiera del Garda to Milan bus From Peschiera del Garda to Milan bus
Bus Jesolo - Milan Bus Jesolo - Milan
Buses from Malaga to Milan Buses from Malaga to Milan
Buses to Messina from Taormina Buses to Messina from Taormina
Buses Giardini Naxos - Messina Buses Giardini Naxos - Messina
Buses Randazzo - Messina Buses Randazzo - Messina
Bus Vibo Valentia to Messina Bus Vibo Valentia to Messina
Popular Airport Shuttles to Milan and to Messina
CheckMyBus › Buses in Italy › Bus to Milan › Bus to Messina

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