Compare all timetables for the bus from Milan to Messina
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 19h 55m | 11:50 PM | Milan | Lampugnano Bus Station | 7:45 PM | Messina | Central Station | Premium Economy | $57 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/24/2026 11:50:00 PM to Central Station, Messina (Italy) arriving at 7/25/2026 7:45:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 19h 55m
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| Itabus | 19h 5m | 10:40 AM | Milan | Lampugnano Bus Station | 5:45 AM | Messina | Central Station | Premium Economy | $74 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/24/2026 10:40:00 AM to Central Station, Messina (Italy) arriving at 7/25/2026 5:45:00 AM. 50 Premium Economy ticket for $74 per person are available. Travel duration is 19h 5m
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| FlixBus | 17h 15m | 1:05 PM | Milan | Lampugnano Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $96 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/24/2026 1:05:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/25/2026 6:20:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 17h 15m
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| FlixBus | 21h 5m | 10:45 PM | Milan | Lampugnano Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $104 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/24/2026 10:45:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/25/2026 7:50:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 21h 5m
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| FlixBus | 20h 30m | 11:20 PM | Milan | San Donato Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $105 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/24/2026 11:20:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/25/2026 7:50:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 20h 30m
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Itabus20h 10m08:00 AMMilanSan Donato Bus Station3:35 PMRomeTiburtina Bus Station0EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 7/26/2026 8:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/26/2026 3:35:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 7h 35m
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Itabus9h 55m06:15 PMRomeTiburtina Bus Station4:10 AMMessinaCentral Station0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/26/2026 6:15:00 PM to Central Station, Messina (Italy) arriving at 7/27/2026 4:10:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 9h 55m
Waiting Time 2h 40m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 20h 10m | 8:00 AM | Milan | San Donato Bus Station | 4:10 AM | Messina | Piazza della Repubblica | Economy | $49 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 7/25/2026 8:00:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 7/26/2026 4:10:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 20h 10m
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| Itabus | 19h 15m | 12:30 AM | Milan | San Donato Bus Station | 7:45 PM | Messina | Central Station | Premium Economy | $57 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 7/25/2026 12:30:00 AM to Central Station, Messina (Italy) arriving at 7/25/2026 7:45:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 19h 15m
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| FlixBus | 21h 20m | 8:35 PM | Milan | Lampugnano Bus Station | 5:55 PM | Messina | Piazza della Repubblica | Economy | $90 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/25/2026 8:35:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/26/2026 5:55:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 21h 20m
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| FlixBus | 20h 45m | 9:10 PM | Milan | San Donato Bus Station | 5:55 PM | Messina | Piazza della Repubblica | Economy | $91 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/25/2026 9:10:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/26/2026 5:55:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 20h 45m
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| Autoservizi Salemi | 17h 55m | 10:45 AM | Milan | San Donato Bus Station | 4:40 AM | Messina | Piazza della Repubblica | Economy | $103 |
A Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 7/25/2026 10:45:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 7/26/2026 4:40:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 17h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 20h 10m | 8:00 AM | Milan | San Donato Bus Station | 4:10 AM | Messina | Central Station | Premium Economy | $40 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 7/26/2026 8:00:00 AM to Central Station, Messina (Italy) arriving at 7/27/2026 4:10:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 20h 10m
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| Itabus | 19h 15m | 12:30 AM | Milan | San Donato Bus Station | 7:45 PM | Messina | Central Station | Premium Economy | $57 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 7/26/2026 12:30:00 AM to Central Station, Messina (Italy) arriving at 7/26/2026 7:45:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 19h 15m
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| FlixBus | 17h 15m | 1:05 PM | Milan | Lampugnano Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $98 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/26/2026 1:05:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/27/2026 6:20:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 17h 15m
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| FlixBus | 21h 5m | 10:45 PM | Milan | Lampugnano Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $99 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/26/2026 10:45:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/27/2026 7:50:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 21h 5m
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| Autoservizi Salemi | 17h 55m | 10:45 AM | Milan | San Donato Bus Station | 4:40 AM | Messina | Piazza della Repubblica | Economy | $100 |
A Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 7/26/2026 10:45:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 7/27/2026 4:40:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 17h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 22h 50m | 8:00 AM | Milan | San Donato Bus Station | 6:50 AM | Messina | Piazza della Repubblica | Economy | $68 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 7/27/2026 8:00:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 7/28/2026 6:50:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 22h 50m
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| Itabus | 19h 5m | 10:40 AM | Milan | Lampugnano Bus Station | 5:45 AM | Messina | Central Station | Premium Economy | $68 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/27/2026 10:40:00 AM to Central Station, Messina (Italy) arriving at 7/28/2026 5:45:00 AM. 50 Premium Economy ticket for $68 per person are available. Travel duration is 19h 5m
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| Autoservizi Salemi | 17h 55m | 10:45 AM | Milan | San Donato Bus Station | 4:40 AM | Messina | Piazza della Repubblica | Economy | $100 |
A Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 7/27/2026 10:45:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 7/28/2026 4:40:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 17h 55m
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| FlixBus | 21h 5m | 10:45 PM | Milan | Lampugnano Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $101 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/27/2026 10:45:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/28/2026 7:50:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 21h 5m
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| FlixBus | 20h 45m | 9:10 PM | Milan | San Donato Bus Station | 5:55 PM | Messina | Piazza della Repubblica | Economy | $101 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/27/2026 9:10:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/28/2026 5:55:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 20h 45m
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FlixBus25h 35m05:15 AMMilanLampugnano Bus Station1:50 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 5:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/28/2026 1:50:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 8h 35m
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Itabus14h 25m04:25 PMRomeTiburtina Bus Station6:50 AMMessinaPiazza della Repubblica0EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/28/2026 4:25:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/29/2026 6:50:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 14h 25m
Waiting Time 2h 35m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 22h 50m | 8:00 AM | Milan | San Donato Bus Station | 6:50 AM | Messina | Piazza della Repubblica | Economy | $67 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 7/28/2026 8:00:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 7/29/2026 6:50:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 22h 50m
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| Itabus | 19h 5m | 10:40 AM | Milan | Lampugnano Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Economy | $70 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 10:40:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 7/29/2026 5:45:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 19h 5m
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| FlixBus | 20h 5m | 3:05 PM | Milan | Lampugnano Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $90 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 3:05:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/29/2026 11:10:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 20h 5m
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| Autoservizi Salemi | 17h 55m | 10:45 AM | Milan | San Donato Bus Station | 4:40 AM | Messina | Piazza della Repubblica | Economy | $100 |
A Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 7/28/2026 10:45:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 7/29/2026 4:40:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 17h 55m
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| FlixBus | 21h 5m | 10:45 PM | Milan | Lampugnano Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $101 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 10:45:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/29/2026 7:50:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 21h 5m
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FlixBus25h 35m05:15 AMMilanLampugnano Bus Station1:50 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 5:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/28/2026 1:50:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 8h 35m
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Itabus14h 25m04:25 PMRomeTiburtina Bus Station6:50 AMMessinaPiazza della Repubblica0EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/28/2026 4:25:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/29/2026 6:50:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 14h 25m
Waiting Time 2h 35m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 19h 55m | 11:50 PM | Milan | Lampugnano Bus Station | 7:45 PM | Messina | Piazza della Repubblica | Economy | $65 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 11:50:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/30/2026 7:45:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 19h 55m
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| Itabus | 19h 5m | 10:40 AM | Milan | Lampugnano Bus Station | 5:45 AM | Messina | Central Station | Premium Economy | $68 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 10:40:00 AM to Central Station, Messina (Italy) arriving at 7/30/2026 5:45:00 AM. 50 Premium Economy ticket for $68 per person are available. Travel duration is 19h 5m
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| FlixBus | 19h 55m | 3:15 PM | Milan | Lampugnano Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $98 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 3:15:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/30/2026 11:10:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 19h 55m
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| Autoservizi Salemi | 18h 40m | 10:00 AM | Milan | Lampugnano Bus Station | 4:40 AM | Messina | Piazza della Repubblica | Economy | $100 |
A Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 10:00:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 7/30/2026 4:40:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 18h 40m
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| Autoservizi Salemi | 17h 55m | 10:45 AM | Milan | San Donato Bus Station | 4:40 AM | Messina | Piazza della Repubblica | Economy | $100 |
A Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 7/29/2026 10:45:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 7/30/2026 4:40:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 17h 55m
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FlixBus25h 35m05:15 AMMilanLampugnano Bus Station1:50 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 5:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/28/2026 1:50:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 8h 35m
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Itabus14h 25m04:25 PMRomeTiburtina Bus Station6:50 AMMessinaPiazza della Repubblica0EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/28/2026 4:25:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/29/2026 6:50:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 14h 25m
Waiting Time 2h 35m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 20h 10m | 8:00 AM | Milan | San Donato Bus Station | 4:10 AM | Messina | Central Station | Premium Economy | $46 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 7/30/2026 8:00:00 AM to Central Station, Messina (Italy) arriving at 7/31/2026 4:10:00 AM. 50 Premium Economy ticket for $46 per person are available. Travel duration is 20h 10m
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| Itabus | 19h 15m | 12:30 AM | Milan | San Donato Bus Station | 7:45 PM | Messina | Central Station | Premium Economy | $57 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 7/30/2026 12:30:00 AM to Central Station, Messina (Italy) arriving at 7/30/2026 7:45:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 19h 15m
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| Itabus | 19h 55m | 11:50 PM | Milan | Lampugnano Bus Station | 7:45 PM | Messina | Central Station | Premium Economy | $57 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/30/2026 11:50:00 PM to Central Station, Messina (Italy) arriving at 7/31/2026 7:45:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 19h 55m
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| FlixBus | 17h 15m | 1:05 PM | Milan | Lampugnano Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $96 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/30/2026 1:05:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 7/31/2026 6:20:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 17h 15m
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| FlixBus | 20h 40m | 9:40 AM | Milan | San Donato Bus Station | 6:20 AM | Messina | Piazza della Repubblica | Economy | $115 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/30/2026 9:40:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 7/31/2026 6:20:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 20h 40m
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Frequency of bus connections between Milan and Messina
Test cheapest views
Facts about the bus from Milan to Messina
Compare all providers like FlixBus, Itabus and Autoservizi Salemi that travel 21 times every day by bus from Milan to Messina in one click! Book your bus ticket from Milan to Messina starting from $40!
| Cheapest Bus | $40 |
| Fastest Bus | 17h 15m |
| Earliest Bus | 10:40 AM |
| Latest Bus | 11:50 PM |
| Daily Bus Routes | 21 Ø |
| Distance | 599.7 miles |
| Bus Companies | FlixBus, Itabus and Autoservizi Salemi |
Cheapest bus connections from Milan to Messina
Every day, 21 buses from 3 bus companies leave Milan for Messina: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/24/2026 and for the following days.
The cheapest time to travel from Milan to Messina
How to save money travelling from Milan to Messina
Book the ticket from Milan to Messina in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Messina, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Messina are also emptier.All bus stations and stops in Milan and Messina
In the map below, you can see where to find all bus stations in Milan and Messina.
Compare the bus with other modes of transport
Service and Comfort on the bus from Milan to Messina
FAQs about the Milan to Messina bus
How much does a Milan Messina bus trip cost?
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On average, how many connections are available from Milan to Messina each day?
How long does a bus journey from Milan to Messina take?
What time is the first bus from Milan to Messina?
What time is the last bus from Milan to Messina?
Which bus companies operate the Milan Messina route?
Is there a direct bus between Milan and Messina?
What can I take with me on the Milan to Messina bus route?
What equipment is available for the Milan Messina bus route?
Available seat classes which are offered on the bus route Milan to Messina
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
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