Bus Mesa, AZ to St. Louis, MO - Compare all Companies

Compare all timetables for the bus from Mesa, AZ to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Mesa, AZ to St. Louis, MO from various bus operators like Greyhound US for the next days.

today

$126

tomorrow

Sunday

$112

Monday

$111

Tuesday

$129

Wednesday

Thursday

$140

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	33h 15m	7:55 PM	Mesa, AZ	Greyhound	7:10 AM	St. Louis, MO	Gateway Station		Economy	$126	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 7/24/2026 7:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/26/2026 7:10:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 33h 15m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	33h 15m	7:55 PM	Mesa, AZ	Greyhound	7:10 AM	St. Louis, MO	Gateway Station		Economy	$112	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 7/26/2026 7:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 7:10:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 33h 15m
	Greyhound US	37h 5m	7:40 AM	Mesa, AZ	Greyhound	10:45 PM	St. Louis, MO	Gateway Station		Economy	$117	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 7/26/2026 7:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/27/2026 10:45:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 37h 5m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	37h 5m	7:40 AM	Mesa, AZ	Greyhound	10:45 PM	St. Louis, MO	Gateway Station		Economy	$111	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 7/27/2026 7:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 10:45:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 37h 5m
	Greyhound US	33h 15m	7:55 PM	Mesa, AZ	Greyhound	7:10 AM	St. Louis, MO	Gateway Station		Economy	$137	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 7/27/2026 7:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/29/2026 7:10:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 33h 15m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	33h 15m	7:55 PM	Mesa, AZ	Greyhound	7:10 AM	St. Louis, MO	Gateway Station		Economy	$129	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 7/28/2026 7:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/30/2026 7:10:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 33h 15m
	Greyhound US	37h 5m	7:40 AM	Mesa, AZ	Greyhound	10:45 PM	St. Louis, MO	Gateway Station		Economy	$133	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 7/28/2026 7:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/29/2026 10:45:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 37h 5m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	37h 5m	7:40 AM	Mesa, AZ	Greyhound	10:45 PM	St. Louis, MO	Gateway Station		Economy	$140	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 7/30/2026 7:40:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/31/2026 10:45:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 37h 5m
	Greyhound US	33h 15m	7:55 PM	Mesa, AZ	Greyhound	7:10 AM	St. Louis, MO	Gateway Station		Economy	$164	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 7/30/2026 7:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/1/2026 7:10:00 AM. 50 Economy ticket for $164 per person are available. Travel duration is 33h 15m

Did you know that if you travel from Mesa, AZ to St. Louis, MO via Phoenix, AZ, you can save more than $17? You can find the corresponding connections below.
- Greyhound US
  
  48h 50m
  
  0
  
  7:55 PM
  
  Mesa, AZ
  Greyhound
  
  8:15 PM
  
  Phoenix, AZ
  Bus Station
  
  0
  
  Economy
  
  $3
  
  A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 7/28/2026 7:55:00 PM to Bus Station, Phoenix, AZ (USA) arriving at 7/28/2026 8:15:00 PM. 50 Economy ticket for $3 per person are available. Travel duration is 0h 20m
- Greyhound US
  
  35h 10m
  
  0
  
  9:35 AM
  
  Phoenix, AZ
  Bus Station
  
  10:45 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $120
  
  A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/29/2026 9:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/30/2026 10:45:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 35h 10m
Travel time is 13h 35m longer, but you will save $17

Best Price Offer: The price for the cheapest bus from Mesa, AZ to St. Louis, MO is $111 on 7/27/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Mesa, AZ and St. Louis, MO

See here how frequent the connections between Mesa, AZ and St. Louis, MO are, during different times and days of the week.

Sunday is the busiest day, with more than 2 daily buses from Mesa, AZ to St. Louis, MO. Friday has instead the fewest connections, with only 1 daily coaches between Mesa, AZ and St. Louis, MO.

The busiest time of the day is the Evening, with 5 buses from Mesa, AZ to St. Louis, MO, while Morning sees the fewest connections between Mesa, AZ and St. Louis, MO, with 4 offers.

Facts about the bus from Mesa, AZ to St. Louis, MO

Compare all providers like Greyhound US that travel 1 times every day by bus from Mesa, AZ to St. Louis, MO in one click! Book your bus ticket from Mesa, AZ to St. Louis, MO starting from $111!

Cheapest Bus	$111
Fastest Bus	35h 15m
Earliest Bus	7:55 PM
Latest Bus	7:55 PM
Daily Bus Routes	1 Ø
Distance	1,258.1 miles
Bus Companies	Greyhound US

Cheapest bus connections from Mesa, AZ to St. Louis, MO

Every day, 1 buses from 1 bus companies leave Mesa, AZ for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

Friday 07/24

$117

Saturday 07/25

Sunday 07/26

$112

Monday 07/27

$111

Tuesday 07/28

$129

Wednesday 07/29

Thursday 07/30

$140

Friday 07/31

Saturday 08/01

$121

Sunday 08/02

Monday 08/03

$119

Tuesday 08/04

Wednesday 08/05

Thursday 08/06

Friday 08/07

Saturday 08/08

$136

Sunday 08/09

Monday 08/10

$122

Tuesday 08/11

Wednesday 08/12

$145

Thursday 08/13

Friday 08/14

Saturday 08/15

The cheapest time to travel from Mesa, AZ to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Mesa, AZ to St. Louis, MO, for the next 30 days.

With a price starting from $111, Monday is the cheapest day for a bus from Mesa, AZ to St. Louis, MO. Thursday instead is the most expensive day with prices starting from $140.

Morning is the cheapest day time for bus tickets from Mesa, AZ to St. Louis, MO, with $111. Evening is the most expensive time of the day with prices starting from $112.

How to save money travelling from Mesa, AZ to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mesa, AZ to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mesa, AZ to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mesa, AZ to St. Louis, MO are also emptier.

All bus stations and stops in Mesa, AZ and St. Louis, MO

In the map below, you can see where to find all bus stations in Mesa, AZ and St. Louis, MO.

Greyhound

S Country Club Dr 1423

Fry’s Fuel Center

W Main Street 1235

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Service and Comfort on the bus from Mesa, AZ to St. Louis, MO

Want to know which seat classes are available on the buses from Mesa, AZ to St. Louis, MO? Or which bus companies serve the route Mesa, AZ to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Mesa, AZ to St. Louis, MO bus

How much does a Mesa, AZ St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $111 and takes 39h 5m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Mesa, AZ to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $111 and $164. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Mesa, AZ to St. Louis, MO each day?

Every day, the Mesa, AZ to St. Louis, MO bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mesa, AZ to St. Louis, MO take?

The fastest bus from Mesa, AZ to St. Louis, MO is offered by Greyhound US and takes 35h 15m. Bus tickets for this connection cost $126. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mesa, AZ to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Mesa, AZ starts at 7:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mesa, AZ to St. Louis, MO?

The latest bus trip departing from Mesa, AZ for St. Louis, MO starts at 7:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mesa, AZ St. Louis, MO route?

When traveling by bus from Mesa, AZ to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mesa, AZ and St. Louis, MO?

You can check all the direct connections between Mesa, AZ and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mesa, AZ to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mesa, AZ St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mesa, AZ St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mesa, AZ to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Mesa, AZ to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mesa, AZ and to St. Louis, MO

Here’s an overview of the most popular bus routes to Mesa, AZ and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!