Bus Washington, DC to St. Louis, MO: Compare prices and save money

Compare all timetables for the bus from Washington, DC to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Washington, DC to St. Louis, MO from various bus operators like Greyhound US or FlixBus for the next days.

today

$123

tomorrow

$90

Wednesday

Thursday

Friday

Saturday

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 20m	5:50 PM	Washington, DC	Union Station	3:10 PM	St. Louis, MO	Gateway Station	Economy	$123	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 9/7/2026 5:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 9/8/2026 3:10:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 22h 20m
Greyhound US	33h 15m	11:30 PM	Washington, DC	Union Station	7:45 AM	St. Louis, MO	Gateway Station	Economy	$126	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 9/7/2026 11:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 9/9/2026 7:45:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 33h 15m
Greyhound US	21h 50m	10:55 AM	Washington, DC	Union Station	7:45 AM	St. Louis, MO	Gateway Station	Economy	$134	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 9/7/2026 10:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 9/8/2026 7:45:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 21h 50m
FlixBus	26h 40m	9:35 PM	Washington, DC	Union Station	11:15 PM	St. Louis, MO	Gateway Station	Economy	$146	A Bus from FlixBus goes from Union Station, Washington, DC (USA) at 9/7/2026 9:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 9/8/2026 11:15:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 26h 40m

Did you know that if you travel from Washington, DC to St. Louis, MO via Pittsburgh, you can save more than $39? You can find the corresponding connections below.
- Greyhound US
  
  29h 15m
  
  0
  
  10:55 AM
  
  Washington, DC
  Union Station
  
  6:20 PM
  
  Pittsburgh
  Grant Street Transportation Center
  
  0
  
  Economy
  
  $28
  
  A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 9/8/2026 10:55:00 AM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 9/8/2026 6:20:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 7h 25m
- Greyhound US
  
  14h 35m
  
  0
  
  1:35 AM
  
  Pittsburgh
  Grant Street Transportation Center
  
  3:10 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $56
  
  A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 9/9/2026 1:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 9/9/2026 3:10:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 14h 35m
Travel time is 8h 25m longer, but you will save $39

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 25m	1:50 AM	Washington, DC	Union Station	11:15 PM	St. Louis, MO	Gateway Station	Economy	$90	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 9/8/2026 1:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 9/8/2026 11:15:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 22h 25m
Greyhound US	22h 35m	5:35 PM	Washington, DC	Union Station	3:10 PM	St. Louis, MO	Gateway Station	Economy	$91	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 9/8/2026 5:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 9/9/2026 3:10:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 22h 35m
FlixBus	24h 55m	9:25 PM	Washington, DC	Union Station	9:20 PM	St. Louis, MO	Gateway Station	Economy	$91	A Bus from FlixBus goes from Union Station, Washington, DC (USA) at 9/8/2026 9:25:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 9/9/2026 9:20:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 24h 55m
FlixBus	24h 40m	11:35 PM	Washington, DC	Union Station	11:15 PM	St. Louis, MO	Gateway Station	Economy	$91	A Bus from FlixBus goes from Union Station, Washington, DC (USA) at 9/8/2026 11:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 9/9/2026 11:15:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 24h 40m
Greyhound US	22h 0m	10:55 AM	Washington, DC	Union Station	7:55 AM	St. Louis, MO	Gateway Station	Economy	$92	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 9/8/2026 10:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 9/9/2026 7:55:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 22h 0m

Frequency of bus connections between Washington, DC and St. Louis, MO

See here how frequent the connections between Washington, DC and St. Louis, MO are, during different times and days of the week.

Monday is the busiest day, with more than 5 daily buses from Washington, DC to St. Louis, MO. Monday has instead the fewest connections, with only 5 daily coaches between Washington, DC and St. Louis, MO.

The busiest time of the day is the Evening, with 4 buses from Washington, DC to St. Louis, MO, while Morning sees the fewest connections between Washington, DC and St. Louis, MO, with 2 offers.

Test cheapest views

The cheapest bus for the 9/12/2026 costs just $78, from Greyhound US

Facts about the bus from Washington, DC to St. Louis, MO

Compare all providers like Greyhound US and FlixBus that travel 5 times every day by bus from Washington, DC to St. Louis, MO in one click! Book your bus ticket from Washington, DC to St. Louis, MO starting from $78!

Cheapest Bus	$78
Fastest Bus	20h 50m
Earliest Bus	1:50 AM
Latest Bus	11:35 PM
Daily Bus Routes	5 Ø
Distance	710.9 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Washington, DC to St. Louis, MO

Every day, 5 buses from 2 bus companies leave Washington, DC for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

$123

Tuesday 09/08

$90

Wednesday 09/09

$86

Thursday 09/10

Friday 09/11

$95

Saturday 09/12

$78

Sunday 09/13

Monday 09/14

$84

Tuesday 09/15

$85

Wednesday 09/16

Thursday 09/17

Friday 09/18

Saturday 09/19

Sunday 09/20

Monday 09/21

$100

Tuesday 09/22

Wednesday 09/23

Thursday 09/24

Friday 09/25

Saturday 09/26

Sunday 09/27

Monday 09/28

Tuesday 09/29

Wednesday 09/30

Thursday 10/01

Friday 10/02

Saturday 10/03

The cheapest time to travel from Washington, DC to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Washington, DC to St. Louis, MO, for the next 30 days.

With a price starting from $84, Monday is the cheapest day for a bus from Washington, DC to St. Louis, MO. Tuesday instead is the most expensive day with prices starting from $85.

Night is the cheapest day time for bus tickets from Washington, DC to St. Louis, MO, with $78. Morning is the most expensive time of the day with prices starting from $92.

How to save money travelling from Washington, DC to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Washington, DC to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Washington, DC to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Washington, DC to St. Louis, MO are also emptier.

All bus stations and stops in Washington, DC and St. Louis, MO

In the map below, you can see where to find all bus stations in Washington, DC and St. Louis, MO.

Union Station

Massachusetts Avenue Northeast 50

Dupont Circle Station

20th St. NW 1525

Armory Metro

19th St SE

Metro Center

11th St NW 663

L'Enfant Plaza outside McDonald's

C Street SW DC 400 C Street SW, Washington, DC 400

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Service and Comfort on the bus from Washington, DC to St. Louis, MO

Want to know which seat classes are available on the buses from Washington, DC to St. Louis, MO? Or which bus companies serve the route Washington, DC to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Washington, DC to St. Louis, MO bus

How much does a Washington, DC St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $78 and takes 21h 25m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Washington, DC to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $78 and $146. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Washington, DC to St. Louis, MO each day?

Every day, the Washington, DC to St. Louis, MO bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Washington, DC to St. Louis, MO take?

The fastest bus from Washington, DC to St. Louis, MO is offered by Greyhound US and takes 20h 50m. Bus tickets for this connection cost $134. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Washington, DC to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Washington, DC starts at 1:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Washington, DC to St. Louis, MO?

The latest bus trip departing from Washington, DC for St. Louis, MO starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Washington, DC St. Louis, MO route?

When traveling by bus from Washington, DC to St. Louis, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Washington, DC and St. Louis, MO?

You can check all the direct connections between Washington, DC and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Washington, DC to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Washington, DC St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Washington, DC St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Washington, DC to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Washington, DC to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Washington, DC and to St. Louis, MO

Here’s an overview of the most popular bus routes to Washington, DC and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!