Bus from Madrid to Brussels from $63

Compare 2 companies and find the best price with CheckMyBus
Search for your destination Millions of deals worldwide
Compare results Save up to 70%
Find the right bus for you Easy and transparent

Compare all timetables for the bus from Madrid to Brussels

Here is a selection of the cheapest bus trips from the schedule from Madrid to Brussels from various bus operators like FlixBus or ALSA for the next days.
today
tomorrow
$123
Saturday
Sunday
$98
Monday
$107
Tuesday
$107
Wednesday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 20m 3:55 PM Madrid Sur Bus Station 4:15 PM Brussels North Station  Economy $123
FlixBus 23h 55m 3:55 PM Madrid Sur Bus Station 3:50 PM Brussels Midi Bus Station  Economy $123
FlixBus 30h 15m 3:55 PM Madrid Sur Bus Station 10:10 PM Brussels Heysel  Economy $126
FlixBus 22h 55m 4:40 PM Madrid Sur Bus Station 3:35 PM Brussels Midi Bus Station  Economy $132
FlixBus 23h 10m 4:40 PM Madrid Sur Bus Station 3:50 PM Brussels Midi Bus Station  Economy $132
  • Did you know that if you travel from Madrid to Brussels via Bordeaux, you can save more than $41? You can find the corresponding connections below.
    • FlixBus
      30h 55m
      0
      3:55 PM
      Madrid
      Sur Bus Station
      3:25 AM
      Bordeaux
      Saint-Jean Bus Stop
      0
      FlixBus
      Economy
      $41
      • Waiting Time 6h 10m
    • BlaBlaCar Bus
      13h 15m
      0
      9:35 AM
      Bordeaux
      Saint Jean Train Station
      10:50 PM
      Brussels
      Midi Bus Station
      0
      BlaBlaCar Bus
      Economy
      $41
    Travel time is 8h 0m longer, but you will save $41

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 22h 40m 3:30 PM Madrid Mendez Alvaro Train Station 2:10 PM Brussels Midi Bus Station  Economy $98
FlixBus 22h 35m 10:35 PM Madrid Sur Bus Station 9:10 PM Brussels North Station  Economy $120
FlixBus 21h 30m 8:25 PM Madrid Sur Bus Station 5:55 PM Brussels Midi Bus Station  Economy $130
FlixBus 24h 15m 10:35 PM Madrid Sur Bus Station 10:50 PM Brussels Midi Bus Station  Economy $132
  • Did you know that if you travel from Madrid to Brussels via Bordeaux, you can save more than $16? You can find the corresponding connections below.
    • FlixBus
      30h 55m
      0
      3:55 PM
      Madrid
      Sur Bus Station
      3:25 AM
      Bordeaux
      Saint-Jean Bus Stop
      0
      FlixBus
      Economy
      $41
      • Waiting Time 6h 10m
    • BlaBlaCar Bus
      13h 15m
      0
      9:35 AM
      Bordeaux
      Saint Jean Train Station
      10:50 PM
      Brussels
      Midi Bus Station
      0
      BlaBlaCar Bus
      Economy
      $41
    Travel time is 9h 25m longer, but you will save $16

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 26h 0m 3:55 PM Madrid Sur Bus Station 5:55 PM Brussels Midi Bus Station  Economy $107
FlixBus 23h 10m 2:50 PM Madrid Sur Bus Station 2:00 PM Brussels North Station  Economy $109
FlixBus 23h 10m 4:40 PM Madrid Sur Bus Station 3:50 PM Brussels Midi Bus Station  Economy $109
FlixBus 24h 20m 3:55 PM Madrid Sur Bus Station 4:15 PM Brussels North Station  Economy $110
FlixBus 23h 55m 3:55 PM Madrid Sur Bus Station 3:50 PM Brussels Midi Bus Station  Economy $110
  • Did you know that if you travel from Madrid to Brussels via Bordeaux, you can save more than $25? You can find the corresponding connections below.
    • FlixBus
      30h 55m
      0
      3:55 PM
      Madrid
      Sur Bus Station
      3:25 AM
      Bordeaux
      Saint-Jean Bus Stop
      0
      FlixBus
      Economy
      $41
      • Waiting Time 6h 10m
    • BlaBlaCar Bus
      13h 15m
      0
      9:35 AM
      Bordeaux
      Saint Jean Train Station
      10:50 PM
      Brussels
      Midi Bus Station
      0
      BlaBlaCar Bus
      Economy
      $41
    Travel time is 7h 45m longer, but you will save $25

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 10m 2:50 PM Madrid Sur Bus Station 2:00 PM Brussels North Station  Economy $107
FlixBus 21h 55m 2:50 PM Madrid Sur Bus Station 12:45 PM Brussels Midi Bus Station  Economy $107
FlixBus 26h 0m 3:55 PM Madrid Sur Bus Station 5:55 PM Brussels Midi Bus Station  Economy $107
FlixBus 24h 20m 3:55 PM Madrid Sur Bus Station 4:15 PM Brussels North Station  Economy $110
FlixBus 23h 55m 3:55 PM Madrid Sur Bus Station 3:50 PM Brussels Midi Bus Station  Economy $110
  • Did you know that if you travel from Madrid to Brussels via Bordeaux, you can save more than $26? You can find the corresponding connections below.
    • FlixBus
      28h 10m
      0
      4:40 PM
      Madrid
      Sur Bus Station
      2:00 AM
      Bordeaux
      Saint-Jean Bus Stop
      0
      FlixBus
      Economy
      $48
      • Waiting Time 5h 20m
    • BlaBlaCar Bus
      13h 30m
      0
      7:20 AM
      Bordeaux
      Saint Jean Train Station
      8:50 PM
      Brussels
      Midi Bus Station
      0
      BlaBlaCar Bus
      Economy
      $33
    Travel time is 6h 15m longer, but you will save $26

Frequency of bus connections between Madrid and Brussels

See here how frequent the connections between Madrid and Brussels are, during different times and days of the week.
Friday is the busiest day, with more than 14 daily buses from Madrid to Brussels. Sunday has instead the fewest connections, with only 9 daily coaches between Madrid and Brussels.
The busiest time of the day is the Afternoon, with 37 buses from Madrid to Brussels, while Evening sees the fewest connections between Madrid and Brussels, with 12 offers.

Test cheapest views

The cheapest bus for the 7/21/2026 costs just $63, from ALSA

Facts about the bus from Madrid to Brussels

Compare all providers like FlixBus and ALSA that travel 12 times every day by bus from Madrid to Brussels in one click! Book your bus ticket from Madrid to Brussels starting from $63!

Cheapest Bus $63
Fastest Bus 21h 30m
Earliest Bus 2:50 PM
Latest Bus 10:35 PM
Daily Bus Routes 12 Ø
Distance 818.4 miles
Bus Companies FlixBus and ALSA

Cheapest bus connections from Madrid to Brussels

Every day, 12 buses from 2 bus companies leave Madrid for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/23/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/19
Monday 07/20
Tuesday 07/21
Wednesday 07/22
Thursday 07/23
$71
Friday 07/24
$123
Saturday 07/25
Sunday 07/26
$98
Monday 07/27
$73
Tuesday 07/28
$77
Wednesday 07/29
Thursday 07/30
Friday 07/31
Saturday 08/01
Sunday 08/02
$129
Monday 08/03
Tuesday 08/04
$73
Wednesday 08/05
$76
Thursday 08/06
$91
Friday 08/07
$116
Saturday 08/08
Sunday 08/09
$77
Monday 08/10
Tuesday 08/11
Wednesday 08/12
$98
Thursday 08/13
$100
Friday 08/14
Saturday 08/15

The cheapest time to travel from Madrid to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Madrid to Brussels, for the next 30 days.
With a price starting from $73, Monday is the cheapest day for a bus from Madrid to Brussels. Friday instead is the most expensive day with prices starting from $116.
Afternoon is the cheapest day time for bus tickets from Madrid to Brussels, with $98. Evening is the most expensive time of the day with prices starting from $120.

How to save money travelling from Madrid to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madrid to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madrid to Brussels are also emptier.

All bus stations and stops in Madrid and Brussels

In the map below, you can see where to find all bus stations in Madrid and Brussels.

Service and Comfort on the bus from Madrid to Brussels

Want to know which seat classes are available on the buses from Madrid to Brussels? Or which bus companies serve the route Madrid to Brussels? Below you will find answers to your questions.

FAQs about the Madrid to Brussels bus

How much does a Madrid Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $63 and takes 22h 40m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Madrid to Brussels?

This route is offered by 2 companies with a range of ticket prices between $63 and $178. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Madrid to Brussels each day?

Every day, the Madrid to Brussels bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Madrid to Brussels take?

The fastest bus from Madrid to Brussels is offered by FlixBus and takes 21h 30m. Bus tickets for this connection cost $169. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Madrid to Brussels?

The earliest bus arriving in Brussels from Madrid starts at 2:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Madrid to Brussels?

The latest bus trip departing from Madrid for Brussels starts at 10:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Madrid Brussels route?

When traveling by bus from Madrid to Brussels, passengers can travel with FlixBus and ALSA. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Madrid and Brussels?

You can check all the direct connections between Madrid and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and ALSA.

What can I take with me on the Madrid to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Madrid Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Madrid Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madrid to Brussels on your planned travel date.

Available seat classes which are offered on the bus route Madrid to Brussels

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madrid and to Brussels

Here’s an overview of the most popular bus routes to Madrid and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Algeciras - Madrid Bus Algeciras - Madrid
Bus Setúbal to Madrid Bus Setúbal to Madrid
Bus from Perugia to Madrid Bus from Perugia to Madrid
From Manchester to Madrid bus From Manchester to Madrid bus
Buses Thessaloniki - Brussels Buses Thessaloniki - Brussels
Buses from Reading to Brussels Buses from Reading to Brussels
Bus Nantes - Brussels Bus Nantes - Brussels
Bus The Hague - Brussels Bus The Hague - Brussels
Popular Airport Shuttles to Madrid and to Brussels
CheckMyBus › Buses in Spain › Bus to Madrid › Bus to Brussels

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.