Bus Milan to Brussels: Compare prices and save money

Compare all timetables for the bus from Milan to Brussels

Here is a selection of the cheapest bus trips from the schedule from Milan to Brussels from various bus operators like FlixBus, BlaBlaCar Bus or European Sleeper for the next days.

today

$49

tomorrow

Wednesday

$46

Thursday

$50

Friday

$46

Saturday

$46

Sunday

$46

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	12h 45m	7:55 PM	Milan	Lampugnano Bus Station	8:40 AM	Brussels	Midi Bus Station	Economy	$49	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 9/7/2026 7:55:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/8/2026 8:40:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 12h 45m
FlixBus	18h 30m	12:15 PM	Milan	Lampugnano Bus Station	6:45 AM	Brussels	North Station	Economy	$52	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/7/2026 12:15:00 PM to North Station, Brussels (Belgium) arriving at 9/8/2026 6:45:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 18h 30m
BlaBlaCar Bus	13h 35m	3:20 PM	Milan	Lampugnano Bus Station	4:55 AM	Brussels	Midi Bus Station	Economy	$52	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 9/7/2026 3:20:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/8/2026 4:55:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 13h 35m
FlixBus	13h 0m	7:40 PM	Milan	Lampugnano Bus Station	8:40 AM	Brussels	North Station	Economy	$56	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/7/2026 7:40:00 PM to North Station, Brussels (Belgium) arriving at 9/8/2026 8:40:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 13h 0m
FlixBus	12h 50m	10:45 PM	Milan	Lampugnano Bus Station	11:35 AM	Brussels	North Station	Economy	$56	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/7/2026 10:45:00 PM to North Station, Brussels (Belgium) arriving at 9/8/2026 11:35:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 12h 50m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	18h 30m	12:15 PM	Milan	Lampugnano Bus Station	6:45 AM	Brussels	North Station	Economy	$46	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/9/2026 12:15:00 PM to North Station, Brussels (Belgium) arriving at 9/10/2026 6:45:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 18h 30m
FlixBus	13h 0m	7:40 PM	Milan	Lampugnano Bus Station	8:40 AM	Brussels	North Station	Economy	$48	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/9/2026 7:40:00 PM to North Station, Brussels (Belgium) arriving at 9/10/2026 8:40:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 13h 0m
FlixBus	17h 15m	10:30 PM	Milan	Lampugnano Bus Station	3:45 PM	Brussels	Midi Bus Station	Economy	$50	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/9/2026 10:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/10/2026 3:45:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 17h 15m
European Sleeper	19h 12m	4:30 PM	Milan	Porta Garibaldi Train Station	11:42 AM	Brussels	Midi Bus Station	Economy	$261	A Bus from European Sleeper goes from Porta Garibaldi Train Station, Milan (Italy) at 9/9/2026 4:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/10/2026 11:42:00 AM. 50 Economy ticket for $261 per person are available. Travel duration is 19h 12m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	18h 30m	12:15 PM	Milan	Lampugnano Bus Station	6:45 AM	Brussels	North Station	Economy	$50	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/10/2026 12:15:00 PM to North Station, Brussels (Belgium) arriving at 9/11/2026 6:45:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 18h 30m
FlixBus	17h 30m	7:15 PM	Milan	Lampugnano Bus Station	12:45 PM	Brussels	Midi Bus Station	Economy	$62	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/10/2026 7:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/11/2026 12:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 17h 30m
FlixBus	16h 25m	4:10 AM	Milan	Lampugnano Bus Station	8:35 PM	Brussels	North Station	Economy	$67	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/10/2026 4:10:00 AM to North Station, Brussels (Belgium) arriving at 9/10/2026 8:35:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 16h 25m
FlixBus	13h 0m	7:40 PM	Milan	Lampugnano Bus Station	8:40 AM	Brussels	North Station	Economy	$73	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/10/2026 7:40:00 PM to North Station, Brussels (Belgium) arriving at 9/11/2026 8:40:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 13h 0m
FlixBus	17h 30m	3:00 PM	Milan	Lampugnano Bus Station	8:30 AM	Brussels	North Station	Economy	$88	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/10/2026 3:00:00 PM to North Station, Brussels (Belgium) arriving at 9/11/2026 8:30:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 17h 30m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	17h 31m	11:59 PM	Milan	Lampugnano Bus Station	5:30 PM	Brussels	Midi Bus Station	Economy	$46	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 9/11/2026 11:59:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/12/2026 5:30:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 17h 31m
BlaBlaCar Bus	17h 40m	10:20 AM	Milan	Lampugnano Bus Station	4:00 AM	Brussels	North Station	Economy	$48	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 9/11/2026 10:20:00 AM to North Station, Brussels (Belgium) arriving at 9/12/2026 4:00:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 17h 40m
FlixBus	13h 0m	7:40 PM	Milan	Lampugnano Bus Station	8:40 AM	Brussels	North Station	Economy	$59	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/11/2026 7:40:00 PM to North Station, Brussels (Belgium) arriving at 9/12/2026 8:40:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 13h 0m
FlixBus	12h 50m	10:45 PM	Milan	Lampugnano Bus Station	11:35 AM	Brussels	North Station	Economy	$59	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/11/2026 10:45:00 PM to North Station, Brussels (Belgium) arriving at 9/12/2026 11:35:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 12h 50m
European Sleeper	19h 42m	4:00 PM	Milan	Porta Garibaldi Train Station	11:42 AM	Brussels	Midi Bus Station	Economy	$285	A Bus from European Sleeper goes from Porta Garibaldi Train Station, Milan (Italy) at 9/11/2026 4:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/12/2026 11:42:00 AM. 50 Economy ticket for $285 per person are available. Travel duration is 19h 42m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	13h 35m	3:20 PM	Milan	Lampugnano Bus Station	4:55 AM	Brussels	Midi Bus Station	Economy	$46	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 9/12/2026 3:20:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/13/2026 4:55:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 13h 35m
BlaBlaCar Bus	17h 40m	10:20 AM	Milan	Lampugnano Bus Station	4:00 AM	Brussels	North Station	Economy	$50	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 9/12/2026 10:20:00 AM to North Station, Brussels (Belgium) arriving at 9/13/2026 4:00:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 17h 40m
BlaBlaCar Bus	17h 31m	11:59 PM	Milan	Lampugnano Bus Station	5:30 PM	Brussels	Midi Bus Station	Economy	$51	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 9/12/2026 11:59:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/13/2026 5:30:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 17h 31m
BlaBlaCar Bus	12h 45m	7:55 PM	Milan	Lampugnano Bus Station	8:40 AM	Brussels	Midi Bus Station	Economy	$58	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 9/12/2026 7:55:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/13/2026 8:40:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 12h 45m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	13h 35m	3:20 PM	Milan	Lampugnano Bus Station	4:55 AM	Brussels	Midi Bus Station	Economy	$46	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 9/13/2026 3:20:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/14/2026 4:55:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 13h 35m
BlaBlaCar Bus	12h 45m	7:55 PM	Milan	Lampugnano Bus Station	8:40 AM	Brussels	Midi Bus Station	Economy	$46	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 9/13/2026 7:55:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/14/2026 8:40:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 12h 45m
FlixBus	12h 50m	10:45 PM	Milan	Lampugnano Bus Station	11:35 AM	Brussels	North Station	Economy	$48	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/13/2026 10:45:00 PM to North Station, Brussels (Belgium) arriving at 9/14/2026 11:35:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 12h 50m
FlixBus	18h 30m	12:15 PM	Milan	Lampugnano Bus Station	6:45 AM	Brussels	North Station	Economy	$73	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/13/2026 12:15:00 PM to North Station, Brussels (Belgium) arriving at 9/14/2026 6:45:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 18h 30m
European Sleeper	20h 12m	3:30 PM	Milan	Porta Garibaldi Train Station	11:42 AM	Brussels	Midi Bus Station	Economy	$261	A Bus from European Sleeper goes from Porta Garibaldi Train Station, Milan (Italy) at 9/13/2026 3:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 9/14/2026 11:42:00 AM. 50 Economy ticket for $261 per person are available. Travel duration is 20h 12m

Frequency of bus connections between Milan and Brussels

See here how frequent the connections between Milan and Brussels are, during different times and days of the week.

Sunday is the busiest day, with more than 14 daily buses from Milan to Brussels. Saturday has instead the fewest connections, with only 4 daily coaches between Milan and Brussels.

The busiest time of the day is the Evening, with 25 buses from Milan to Brussels, while Night sees the fewest connections between Milan and Brussels, with 4 offers.

Test cheapest views

The cheapest bus for the 9/15/2026 costs just $42, from FlixBus

Facts about the bus from Milan to Brussels

Compare all providers like FlixBus, BlaBlaCar Bus and European Sleeper that travel 8 times every day by bus from Milan to Brussels in one click! Book your bus ticket from Milan to Brussels starting from $42!

Cheapest Bus	$42
Fastest Bus	12h 45m
Earliest Bus	4:10 AM
Latest Bus	11:59 PM
Daily Bus Routes	8 Ø
Distance	433.6 miles
Bus Companies	FlixBus, BlaBlaCar Bus and European Sleeper

Cheapest bus connections from Milan to Brussels

Every day, 8 buses from 3 bus companies leave Milan for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

$52

Tuesday 09/08

$50

Wednesday 09/09

$48

Thursday 09/10

$56

Friday 09/11

$46

Saturday 09/12

$46

Sunday 09/13

$46

Monday 09/14

$46

Tuesday 09/15

$42

Wednesday 09/16

$44

Thursday 09/17

$46

Friday 09/18

$46

Saturday 09/19

$44

Sunday 09/20

$46

Monday 09/21

$50

Tuesday 09/22

Wednesday 09/23

Thursday 09/24

$45

Friday 09/25

$45

Saturday 09/26

Sunday 09/27

Monday 09/28

$46

Tuesday 09/29

Wednesday 09/30

Thursday 10/01

Friday 10/02

$46

Saturday 10/03

The cheapest time to travel from Milan to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Brussels, for the next 30 days.

With a price starting from $44, Wednesday is the cheapest day for a bus from Milan to Brussels. Monday instead is the most expensive day with prices starting from $46.

Night is the cheapest day time for bus tickets from Milan to Brussels, with $42. Morning is the most expensive time of the day with prices starting from $48.

How to save money travelling from Milan to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Brussels are also emptier.

Beloved bus companies from Milan to Brussels

These are the most booked bus companies between Milan to Brussels from our users.

BlaBlaCar Bus from Milan to Brussels

Here you will find the key facts about the BlaBlaCar Bus bus route Milan to Brussels:

Cheapest Price	$46
Fastest Bus	12h 45m
Earliest Bus	3:20 PM
Last Bus	11:59 PM
Daily Connections	3 Ø
Found on	8/7/2026

All bus stations and stops in Milan and Brussels

In the map below, you can see where to find all bus stations in Milan and Brussels.

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Central Bus Station

Duomo Bus Stop

Piazza del Duomo

Midi Bus Station

Avenue Fonsny 1

North Station

Rue du Progrès 80

Congrès

Boulevard Pachéco 7

City Tours

Rue du Marché Aux Herbes 82

Delta

PONT DU, Boulevard des Invalides, 1160 BRUXELLES, Belgium

Service and Comfort on the bus from Milan to Brussels

Want to know which seat classes are available on the buses from Milan to Brussels? Or which bus companies serve the route Milan to Brussels? Below you will find answers to your questions.

FAQs about the Milan to Brussels bus

How much does a Milan Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $42 and takes 18h 30m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Milan to Brussels?

This route is offered by 3 companies with a range of ticket prices between $42 and $285. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Milan to Brussels each day?

Every day, the Milan to Brussels bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milan to Brussels take?

The fastest bus from Milan to Brussels is offered by BlaBlaCar Bus and takes 12h 45m. Bus tickets for this connection cost $49. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milan to Brussels?

The earliest bus arriving in Brussels from Milan starts at 4:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milan to Brussels?

The latest bus trip departing from Milan for Brussels starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milan Brussels route?

When traveling by bus from Milan to Brussels, passengers can travel with FlixBus, BlaBlaCar Bus and European Sleeper. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milan and Brussels?

You can check all the direct connections between Milan and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, BlaBlaCar Bus and European Sleeper.

What can I take with me on the Milan to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milan Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Brussels on your planned travel date.

Available seat classes which are offered on the bus route Milan to Brussels

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milan and to Brussels

Here’s an overview of the most popular bus routes to Milan and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!