Bus Lyon to Madrid - Compare all Companies

Compare all timetables for the bus from Lyon to Madrid

Here is a selection of the cheapest bus trips from the schedule from Lyon to Madrid from various bus operators like FlixBus, ALSA or BlaBlaCar Bus for the next days.

today

$44

tomorrow

$57

Friday

$63

Saturday

$47

Sunday

$47

Monday

$68

Tuesday

$65

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ALSA	17h 15m	8:50 PM	Lyon		2:05 PM	Madrid	Mendez Alvaro Train Station	Economy	$44	A Bus from ALSA goes from , Lyon (France) at 7/22/2026 8:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/23/2026 2:05:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 17h 15m
BlaBlaCar Bus	17h 10m	8:55 PM	Lyon	Perrache Train Station	2:05 PM	Madrid	Sur Bus Station	Economy	$49	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/22/2026 8:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/23/2026 2:05:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 17h 10m
BlaBlaCar Bus	17h 25m	4:30 PM	Lyon	Perrache Train Station	9:55 AM	Madrid	Sur Bus Station	Economy	$57	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/22/2026 4:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/23/2026 9:55:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 17h 25m
FlixBus	16h 40m	4:00 PM	Lyon		8:40 AM	Madrid	Sur Bus Station	Economy	$59	A Bus from FlixBus goes from , Lyon (France) at 7/22/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/23/2026 8:40:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 16h 40m
FlixBus	16h 40m	5:00 PM	Lyon		9:40 AM	Madrid	Sur Bus Station	Economy	$59	A Bus from FlixBus goes from , Lyon (France) at 7/22/2026 5:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/23/2026 9:40:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 16h 40m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Arrival time	To	Destination	Seat classes	Price
FlixBus	16h 40m	5:00 PM	Lyon	9:40 AM	Madrid	Sur Bus Station	Economy	$57	A Bus from FlixBus goes from , Lyon (France) at 7/23/2026 5:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/24/2026 9:40:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 16h 40m
FlixBus	16h 40m	4:00 PM	Lyon	8:40 AM	Madrid	Sur Bus Station	Economy	$68	A Bus from FlixBus goes from , Lyon (France) at 7/23/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/24/2026 8:40:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 16h 40m
ALSA	17h 25m	4:30 PM	Lyon	9:55 AM	Madrid	Mendez Alvaro Train Station	Economy	$79	A Bus from ALSA goes from , Lyon (France) at 7/23/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/24/2026 9:55:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 25m
ALSA	17h 55m	10:50 PM	Lyon	4:45 PM	Madrid	Mendez Alvaro Train Station	Economy	$84	A Bus from ALSA goes from , Lyon (France) at 7/23/2026 10:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/24/2026 4:45:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 17h 55m
FlixBus	19h 45m	12:10 PM	Lyon	7:55 AM	Madrid	Sur Bus Station	Economy	$121	A Bus from FlixBus goes from , Lyon (France) at 7/23/2026 12:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/24/2026 7:55:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 19h 45m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	17h 25m	4:30 PM	Lyon	Perrache Train Station	9:55 AM	Madrid	Sur Bus Station	Economy	$63	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/24/2026 4:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/25/2026 9:55:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 17h 25m
FlixBus	16h 40m	5:00 PM	Lyon		9:40 AM	Madrid	Sur Bus Station	Economy	$66	A Bus from FlixBus goes from , Lyon (France) at 7/24/2026 5:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/25/2026 9:40:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 16h 40m
Union Ivkoni	19h 15m	2:15 PM	Lyon		9:30 AM	Madrid	Mendez Alvaro Train Station	Economy	$74	A Bus from Union Ivkoni goes from , Lyon (France) at 7/24/2026 2:15:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/25/2026 9:30:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 19h 15m
BlaBlaCar Bus	23h 10m	4:00 PM	Lyon	Perrache Train Station	3:10 PM	Madrid	Sur Bus Station	Economy	$77	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/24/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/25/2026 3:10:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 23h 10m
FlixBus	16h 40m	4:00 PM	Lyon		8:40 AM	Madrid	Sur Bus Station	Economy	$80	A Bus from FlixBus goes from , Lyon (France) at 7/24/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/25/2026 8:40:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 16h 40m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ALSA	17h 25m	4:30 PM	Lyon		9:55 AM	Madrid	Mendez Alvaro Train Station	Economy	$47	A Bus from ALSA goes from , Lyon (France) at 7/25/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/26/2026 9:55:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 17h 25m
FlixBus	16h 40m	5:00 PM	Lyon		9:40 AM	Madrid	Sur Bus Station	Economy	$73	A Bus from FlixBus goes from , Lyon (France) at 7/25/2026 5:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/26/2026 9:40:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 40m
ALSA	17h 55m	10:50 PM	Lyon		4:45 PM	Madrid	Mendez Alvaro Train Station	Economy	$79	A Bus from ALSA goes from , Lyon (France) at 7/25/2026 10:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/26/2026 4:45:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 55m
FlixBus	16h 40m	4:00 PM	Lyon		8:40 AM	Madrid	Sur Bus Station	Economy	$84	A Bus from FlixBus goes from , Lyon (France) at 7/25/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/26/2026 8:40:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 16h 40m
BlaBlaCar Bus	19h 45m	2:00 PM	Lyon	Perrache Train Station	9:45 AM	Madrid	Sur Bus Station	Economy	$125	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/25/2026 2:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/26/2026 9:45:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 19h 45m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ALSA	17h 25m	4:30 PM	Lyon		9:55 AM	Madrid	Mendez Alvaro Train Station	Economy	$47	A Bus from ALSA goes from , Lyon (France) at 7/26/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/27/2026 9:55:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 17h 25m
FlixBus	16h 40m	5:00 PM	Lyon		9:40 AM	Madrid	Sur Bus Station	Economy	$65	A Bus from FlixBus goes from , Lyon (France) at 7/26/2026 5:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/27/2026 9:40:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 16h 40m
FlixBus	16h 40m	4:00 PM	Lyon		8:40 AM	Madrid	Sur Bus Station	Economy	$75	A Bus from FlixBus goes from , Lyon (France) at 7/26/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/27/2026 8:40:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 16h 40m
ALSA	17h 55m	10:50 PM	Lyon		4:45 PM	Madrid	Mendez Alvaro Train Station	Economy	$79	A Bus from ALSA goes from , Lyon (France) at 7/26/2026 10:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/27/2026 4:45:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 55m
BlaBlaCar Bus	17h 10m	8:55 PM	Lyon	Perrache Train Station	2:05 PM	Madrid	Sur Bus Station	Economy	$80	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/26/2026 8:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/27/2026 2:05:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 17h 10m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	17h 25m	4:30 PM	Lyon	Perrache Train Station	9:55 AM	Madrid	Sur Bus Station	Economy	$68	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/27/2026 4:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/28/2026 9:55:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 17h 25m
ALSA	17h 55m	10:50 PM	Lyon		4:45 PM	Madrid	Mendez Alvaro Train Station	Economy	$79	A Bus from ALSA goes from , Lyon (France) at 7/27/2026 10:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/28/2026 4:45:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 55m
BlaBlaCar Bus	23h 10m	4:00 PM	Lyon	Perrache Train Station	3:10 PM	Madrid	Sur Bus Station	Economy	$89	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/27/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/28/2026 3:10:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 23h 10m
FlixBus	16h 40m	4:00 PM	Lyon		8:40 AM	Madrid	Sur Bus Station	Economy	$101	A Bus from FlixBus goes from , Lyon (France) at 7/27/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/28/2026 8:40:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 16h 40m
FlixBus	16h 40m	5:00 PM	Lyon		9:40 AM	Madrid	Sur Bus Station	Economy	$101	A Bus from FlixBus goes from , Lyon (France) at 7/27/2026 5:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/28/2026 9:40:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 16h 40m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Internorte Transportes	16h 55m	4:30 PM	Lyon	Part-Dieu Train Station	9:25 AM	Madrid	Benavente Bus Station	Economy	$65	A Bus from Internorte Transportes goes from Part-Dieu Train Station, Lyon (France) at 7/28/2026 4:30:00 PM to Benavente Bus Station, Madrid (Spain) arriving at 7/29/2026 9:25:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 16h 55m
Internorte Transportes	17h 55m	10:50 PM	Lyon	Part-Dieu Train Station	4:45 PM	Madrid	Benavente Bus Station	Economy	$65	A Bus from Internorte Transportes goes from Part-Dieu Train Station, Lyon (France) at 7/28/2026 10:50:00 PM to Benavente Bus Station, Madrid (Spain) arriving at 7/29/2026 4:45:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 17h 55m
BlaBlaCar Bus	17h 25m	4:30 PM	Lyon	Perrache Train Station	9:55 AM	Madrid	Sur Bus Station	Economy	$68	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/28/2026 4:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/29/2026 9:55:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 17h 25m
BlaBlaCar Bus	23h 10m	4:00 PM	Lyon	Perrache Train Station	3:10 PM	Madrid	Sur Bus Station	Economy	$77	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/28/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/29/2026 3:10:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 23h 10m
FlixBus	16h 40m	4:00 PM	Lyon		8:40 AM	Madrid	Sur Bus Station	Economy	$90	A Bus from FlixBus goes from , Lyon (France) at 7/28/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/29/2026 8:40:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 16h 40m

Best Price Offer: The price for the cheapest bus from Lyon to Madrid is $44 on 7/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Lyon and Madrid

See here how frequent the connections between Lyon and Madrid are, during different times and days of the week.

Tuesday is the busiest day, with more than 20 daily buses from Lyon to Madrid. Wednesday has instead the fewest connections, with only 8 daily coaches between Lyon and Madrid.

The busiest time of the day is the Afternoon, with 64 buses from Lyon to Madrid, while Night sees the fewest connections between Lyon and Madrid, with 6 offers.

Facts about the bus from Lyon to Madrid

Compare all providers like FlixBus, ALSA and BlaBlaCar Bus that travel 14 times every day by bus from Lyon to Madrid in one click! Book your bus ticket from Lyon to Madrid starting from $44!

Cheapest Bus	$44
Fastest Bus	16h 40m
Earliest Bus	4:00 PM
Latest Bus	10:50 PM
Daily Bus Routes	14 Ø
Distance	566.9 miles
Bus Companies	FlixBus, ALSA, BlaBlaCar Bus, Internorte Transportes and Union Ivkoni

Cheapest bus connections from Lyon to Madrid

Every day, 14 buses from 5 bus companies leave Lyon for Madrid: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

$44

Thursday 07/23

$60

Friday 07/24

$68

Saturday 07/25

$47

Sunday 07/26

$51

Monday 07/27

$68

Tuesday 07/28

$68

Wednesday 07/29

$56

Thursday 07/30

$47

Friday 07/31

$47

Saturday 08/01

$92

Sunday 08/02

$111

Monday 08/03

$79

Tuesday 08/04

$68

Wednesday 08/05

$49

Thursday 08/06

$79

Friday 08/07

$56

Saturday 08/08

$87

Sunday 08/09

$76

Monday 08/10

$79

Tuesday 08/11

$79

Wednesday 08/12

$45

Thursday 08/13

$90

Friday 08/14

$44

Saturday 08/15

The cheapest time to travel from Lyon to Madrid

See here on which day and which time of the day you can find the cheapest bus ticket from Lyon to Madrid, for the next 30 days.

With a price starting from $44, Wednesday is the cheapest day for a bus from Lyon to Madrid. Monday instead is the most expensive day with prices starting from $68.

Evening is the cheapest day time for bus tickets from Lyon to Madrid, with $44. Morning is the most expensive time of the day with prices starting from $126.

How to save money travelling from Lyon to Madrid

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lyon to Madrid in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lyon to Madrid, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lyon to Madrid are also emptier.

Latest reviews for bus companies on the route Lyon - Madrid

Haddam, 8/8/2024

Le bus n’est jamais passé quand j’essaye de prendre des informations. On m’a dit donc que le bus était passé alors qu’il est jamais passé. Aucun remboursement, aucune iinformation concrète à fuir

All bus stations and stops in Lyon and Madrid

In the map below, you can see where to find all bus stations in Lyon and Madrid.

Perrache Bus Stop

Cours de Verdun 14

Saint Paul Train Station

Pont Kitchener R.G. Bus Stop

Cours de Verdun

Maison Carrée Bus Stop

Les Charrières 69570

Girondins - Yves Farge Bus Stop

Avenida de América Bus Station

Avenida de América 13

Bus Stop

Calle de Tiziano 40

Intercambiador de Moncloa

Calle de la Princesa 89n

Plaza de Castilla

Sur Bus Station

Calle de Méndez Álvaro 83

Service and Comfort on the bus from Lyon to Madrid

Want to know which seat classes are available on the buses from Lyon to Madrid? Or which bus companies serve the route Lyon to Madrid? Below you will find answers to your questions.

FAQs about the Lyon to Madrid bus

How much does a Lyon Madrid bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $44 and takes 17h 15m to reach Madrid. Compare offers to save money!

How much could I save by comparing buses from Lyon to Madrid?

This route is offered by 5 companies with a range of ticket prices between $44 and $267. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Madrid.

On average, how many connections are available from Lyon to Madrid each day?

Every day, the Lyon to Madrid bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lyon to Madrid take?

The fastest bus from Lyon to Madrid is offered by FlixBus and takes 16h 40m. Bus tickets for this connection cost $59. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lyon to Madrid?

The earliest bus arriving in Madrid from Lyon starts at 4:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lyon to Madrid?

The latest bus trip departing from Lyon for Madrid starts at 10:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lyon Madrid route?

When traveling by bus from Lyon to Madrid, passengers can travel with FlixBus, ALSA and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lyon and Madrid?

You can check all the direct connections between Lyon and Madrid by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, ALSA and BlaBlaCar Bus.

What can I take with me on the Lyon to Madrid bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lyon Madrid bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lyon Madrid bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lyon to Madrid on your planned travel date.

Available seat classes which are offered on the bus route Lyon to Madrid

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lyon and to Madrid

Here’s an overview of the most popular bus routes to Lyon and to Madrid. Simply click on the connection of your choice, and you will find all the details about your bus route!