Bus Brussels to Lyon - Compare all Companies

Compare all timetables for the bus from Brussels to Lyon

Here is a selection of the cheapest bus trips from the schedule from Brussels to Lyon from various bus operators like FlixBus or BlaBlaCar Bus for the next days.

today

$26

tomorrow

$24

Wednesday

$24

Thursday

$24

Friday

$26

Saturday

$26

Sunday

$28

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	15h 15m	8:00 AM	Brussels	North Station	11:15 PM	Lyon		Economy	$26	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/7/2026 8:00:00 AM to , Lyon (France) arriving at 9/7/2026 11:15:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 15h 15m
FlixBus	12h 25m	10:55 PM	Brussels	North Station	11:20 AM	Lyon		Economy	$26	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/7/2026 10:55:00 PM to , Lyon (France) arriving at 9/8/2026 11:20:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 12h 25m
FlixBus	12h 45m	11:05 AM	Brussels	Midi Bus Station	11:50 PM	Lyon		Economy	$27	A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 9/7/2026 11:05:00 AM to , Lyon (France) arriving at 9/7/2026 11:50:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 12h 45m
BlaBlaCar Bus	11h 30m	7:20 AM	Brussels	Midi Bus Station	6:50 PM	Lyon	Perrache Train Station	Economy	$28	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/7/2026 7:20:00 AM to Perrache Train Station, Lyon (France) arriving at 9/7/2026 6:50:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 11h 30m
BlaBlaCar Bus	12h 50m	11:30 AM	Brussels	Midi Bus Station	12:20 AM	Lyon	Perrache Train Station	Economy	$28	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/7/2026 11:30:00 AM to Perrache Train Station, Lyon (France) arriving at 9/8/2026 12:20:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 12h 50m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	11h 50m	12:00 PM	Brussels	North Station	11:50 PM	Lyon		Economy	$24	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/8/2026 12:00:00 PM to , Lyon (France) arriving at 9/8/2026 11:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 11h 50m
FlixBus	13h 45m	10:05 AM	Brussels	Midi Bus Station	11:50 PM	Lyon		Economy	$24	A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 9/8/2026 10:05:00 AM to , Lyon (France) arriving at 9/8/2026 11:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 13h 45m
FlixBus	12h 45m	11:05 AM	Brussels	Midi Bus Station	11:50 PM	Lyon		Economy	$24	A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 9/8/2026 11:05:00 AM to , Lyon (France) arriving at 9/8/2026 11:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 12h 45m
BlaBlaCar Bus	13h 14m	3:11 AM	Brussels	Midi Bus Station	4:25 PM	Lyon	Perrache Train Station	Economy	$28	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/8/2026 3:11:00 AM to Perrache Train Station, Lyon (France) arriving at 9/8/2026 4:25:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 13h 14m
BlaBlaCar Bus	10h 15m	7:05 PM	Brussels	Midi Bus Station	5:20 AM	Lyon	Perrache Train Station	Economy	$28	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/8/2026 7:05:00 PM to Perrache Train Station, Lyon (France) arriving at 9/9/2026 5:20:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 10h 15m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 45m	11:05 AM	Brussels	Midi Bus Station	11:50 PM	Lyon		Economy	$24	A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 9/9/2026 11:05:00 AM to , Lyon (France) arriving at 9/9/2026 11:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 12h 45m
FlixBus	11h 50m	12:00 PM	Brussels	North Station	11:50 PM	Lyon		Economy	$27	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/9/2026 12:00:00 PM to , Lyon (France) arriving at 9/9/2026 11:50:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 50m
FlixBus	14h 0m	12:45 AM	Brussels	North Station	2:45 PM	Lyon		Economy	$28	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/9/2026 12:45:00 AM to , Lyon (France) arriving at 9/9/2026 2:45:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 14h 0m
BlaBlaCar Bus	14h 0m	1:30 PM	Brussels	Midi Bus Station	3:30 AM	Lyon	Perrache Train Station	Economy	$28	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/9/2026 1:30:00 PM to Perrache Train Station, Lyon (France) arriving at 9/10/2026 3:30:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 14h 0m
BlaBlaCar Bus	10h 10m	5:55 PM	Brussels	Midi Bus Station	4:05 AM	Lyon	Perrache Train Station	Economy	$28	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/9/2026 5:55:00 PM to Perrache Train Station, Lyon (France) arriving at 9/10/2026 4:05:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 10h 10m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	11h 40m	3:30 PM	Brussels	North Station	3:10 AM	Lyon		Economy	$24	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/10/2026 3:30:00 PM to , Lyon (France) arriving at 9/11/2026 3:10:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 11h 40m
FlixBus	12h 10m	4:40 PM	Brussels	North Station	4:50 AM	Lyon		Economy	$24	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/10/2026 4:40:00 PM to , Lyon (France) arriving at 9/11/2026 4:50:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 12h 10m
FlixBus	13h 45m	10:05 AM	Brussels	Midi Bus Station	11:50 PM	Lyon		Economy	$24	A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 9/10/2026 10:05:00 AM to , Lyon (France) arriving at 9/10/2026 11:50:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 13h 45m
BlaBlaCar Bus	10h 30m	2:20 PM	Brussels	Midi Bus Station	12:50 AM	Lyon	Perrache Train Station	Economy	$26	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/10/2026 2:20:00 PM to Perrache Train Station, Lyon (France) arriving at 9/11/2026 12:50:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 10h 30m
BlaBlaCar Bus	10h 55m	4:35 PM	Brussels	Midi Bus Station	3:30 AM	Lyon	Perrache Train Station	Economy	$26	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/10/2026 4:35:00 PM to Perrache Train Station, Lyon (France) arriving at 9/11/2026 3:30:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 10h 55m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	10h 30m	2:20 PM	Brussels	Midi Bus Station	12:50 AM	Lyon	Perrache Train Station	Economy	$26	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/11/2026 2:20:00 PM to Perrache Train Station, Lyon (France) arriving at 9/12/2026 12:50:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 10h 30m
BlaBlaCar Bus	10h 15m	7:05 PM	Brussels	Midi Bus Station	5:20 AM	Lyon	Perrache Train Station	Economy	$26	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/11/2026 7:05:00 PM to Perrache Train Station, Lyon (France) arriving at 9/12/2026 5:20:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 10h 15m
FlixBus	11h 40m	3:30 PM	Brussels	North Station	3:10 AM	Lyon		Economy	$28	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/11/2026 3:30:00 PM to , Lyon (France) arriving at 9/12/2026 3:10:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 11h 40m
BlaBlaCar Bus	11h 30m	7:20 AM	Brussels	Midi Bus Station	6:50 PM	Lyon	Perrache Train Station	Economy	$28	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/11/2026 7:20:00 AM to Perrache Train Station, Lyon (France) arriving at 9/11/2026 6:50:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 11h 30m
FlixBus	12h 50m	8:00 AM	Brussels	North Station	8:50 PM	Lyon		Economy	$30	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/11/2026 8:00:00 AM to , Lyon (France) arriving at 9/11/2026 8:50:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 12h 50m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	11h 30m	7:20 AM	Brussels	Midi Bus Station	6:50 PM	Lyon	Perrache Train Station	Economy	$26	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/12/2026 7:20:00 AM to Perrache Train Station, Lyon (France) arriving at 9/12/2026 6:50:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 11h 30m
BlaBlaCar Bus	10h 50m	1:30 PM	Brussels	Midi Bus Station	12:20 AM	Lyon	Perrache Train Station	Economy	$26	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/12/2026 1:30:00 PM to Perrache Train Station, Lyon (France) arriving at 9/13/2026 12:20:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 10h 50m
BlaBlaCar Bus	10h 35m	4:55 PM	Brussels	Midi Bus Station	3:30 AM	Lyon	Perrache Train Station	Economy	$26	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/12/2026 4:55:00 PM to Perrache Train Station, Lyon (France) arriving at 9/13/2026 3:30:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 10h 35m
FlixBus	10h 50m	1:00 PM	Brussels	North Station	11:50 PM	Lyon		Economy	$27	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/12/2026 1:00:00 PM to , Lyon (France) arriving at 9/12/2026 11:50:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 10h 50m
FlixBus	11h 40m	3:30 PM	Brussels	North Station	3:10 AM	Lyon		Economy	$27	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/12/2026 3:30:00 PM to , Lyon (France) arriving at 9/13/2026 3:10:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 40m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	10h 30m	2:20 PM	Brussels	Midi Bus Station	12:50 AM	Lyon	Perrache Train Station	Economy	$28	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/13/2026 2:20:00 PM to Perrache Train Station, Lyon (France) arriving at 9/14/2026 12:50:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 10h 30m
FlixBus	12h 25m	10:55 PM	Brussels	North Station	11:20 AM	Lyon		Economy	$31	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/13/2026 10:55:00 PM to , Lyon (France) arriving at 9/14/2026 11:20:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 12h 25m
FlixBus	11h 10m	4:15 AM	Brussels	Midi Bus Station	3:25 PM	Lyon		Economy	$31	A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 9/13/2026 4:15:00 AM to , Lyon (France) arriving at 9/13/2026 3:25:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 11h 10m
BlaBlaCar Bus	10h 15m	7:05 PM	Brussels	Midi Bus Station	5:20 AM	Lyon	Perrache Train Station	Economy	$31	A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 9/13/2026 7:05:00 PM to Perrache Train Station, Lyon (France) arriving at 9/14/2026 5:20:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 10h 15m
FlixBus	12h 10m	12:45 AM	Brussels	North Station	12:55 PM	Lyon		Economy	$32	A Bus from FlixBus goes from North Station, Brussels (Belgium) at 9/13/2026 12:45:00 AM to , Lyon (France) arriving at 9/13/2026 12:55:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 12h 10m

Best Price Offer: The price for the cheapest bus from Brussels to Lyon is $19 on 9/21/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Brussels and Lyon

See here how frequent the connections between Brussels and Lyon are, during different times and days of the week.

Sunday is the busiest day, with more than 26 daily buses from Brussels to Lyon. Tuesday has instead the fewest connections, with only 15 daily coaches between Brussels and Lyon.

The busiest time of the day is the Afternoon, with 60 buses from Brussels to Lyon, while Morning sees the fewest connections between Brussels and Lyon, with 23 offers.

Facts about the bus from Brussels to Lyon

Compare all providers like FlixBus and BlaBlaCar Bus that travel 21 times every day by bus from Brussels to Lyon in one click! Book your bus ticket from Brussels to Lyon starting from $19!

Cheapest Bus	$19
Fastest Bus	10h 10m
Earliest Bus	12:45 AM
Latest Bus	10:55 PM
Daily Bus Routes	21 Ø
Distance	352.7 miles
Bus Companies	FlixBus and BlaBlaCar Bus

Cheapest bus connections from Brussels to Lyon

Every day, 21 buses from 2 bus companies leave Brussels for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

$26

Tuesday 09/08

$55

Wednesday 09/09

$47

Thursday 09/10

$24

Friday 09/11

$26

Saturday 09/12

$26

Sunday 09/13

$33

Monday 09/14

$24

Tuesday 09/15

$21

Wednesday 09/16

$22

Thursday 09/17

$24

Friday 09/18

$27

Saturday 09/19

Sunday 09/20

$29

Monday 09/21

$19

Tuesday 09/22

Wednesday 09/23

Thursday 09/24

Friday 09/25

Saturday 09/26

$22

Sunday 09/27

Monday 09/28

Tuesday 09/29

Wednesday 09/30

$22

Thursday 10/01

Friday 10/02

Saturday 10/03

The cheapest time to travel from Brussels to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Brussels to Lyon, for the next 30 days.

With a price starting from $19, Monday is the cheapest day for a bus from Brussels to Lyon. Sunday instead is the most expensive day with prices starting from $28.

Night is the cheapest day time for bus tickets from Brussels to Lyon, with $19. Evening is the most expensive time of the day with prices starting from $26.

How to save money travelling from Brussels to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Brussels to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Brussels to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Brussels to Lyon are also emptier.

All bus stations and stops in Brussels and Lyon

In the map below, you can see where to find all bus stations in Brussels and Lyon.

Midi Bus Station

Avenue Fonsny 1

North Station

Rue du Progrès 80

Congrès

Boulevard Pachéco 7

City Tours

Rue du Marché Aux Herbes 82

Delta

PONT DU, Boulevard des Invalides, 1160 BRUXELLES, Belgium

Perrache Bus Stop

Cours de Verdun 14

Saint Paul Train Station

Pont Kitchener R.G. Bus Stop

Cours de Verdun

Maison Carrée Bus Stop

Les Charrières 69570

Girondins - Yves Farge Bus Stop

Service and Comfort on the bus from Brussels to Lyon

Want to know which seat classes are available on the buses from Brussels to Lyon? Or which bus companies serve the route Brussels to Lyon? Below you will find answers to your questions.

FAQs about the Brussels to Lyon bus

How much does a Brussels Lyon bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $19 and takes 11h 50m to reach Lyon. Compare offers to save money!

How much could I save by comparing buses from Brussels to Lyon?

This route is offered by 2 companies with a range of ticket prices between $19 and $88. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lyon.

On average, how many connections are available from Brussels to Lyon each day?

Every day, the Brussels to Lyon bus route is served by approximately 21 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Brussels to Lyon take?

The fastest bus from Brussels to Lyon is offered by BlaBlaCar Bus and takes 10h 10m. Bus tickets for this connection cost $28. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Brussels to Lyon?

The earliest bus arriving in Lyon from Brussels starts at 12:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Brussels to Lyon?

The latest bus trip departing from Brussels for Lyon starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Brussels Lyon route?

When traveling by bus from Brussels to Lyon, passengers can travel with FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Brussels and Lyon?

You can check all the direct connections between Brussels and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the Brussels to Lyon bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Brussels Lyon bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Brussels Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Brussels to Lyon on your planned travel date.

Available seat classes which are offered on the bus route Brussels to Lyon

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Brussels and to Lyon

Here’s an overview of the most popular bus routes to Brussels and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!