Bus Luxembourg City to Prague - Compare all Companies

Compare all timetables for the bus from Luxembourg City to Prague

Here is a selection of the cheapest bus trips from the schedule from Luxembourg City to Prague from various bus operators like FlixBus for the next days.

today

$33

tomorrow

Friday

$49

Saturday

Sunday

$42

Monday

Tuesday

$28

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 50m	10:55 AM	Luxembourg City	P+R Bouillon	12:45 AM	Prague	Wilsonova Bus Station	Economy	$33	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/9/2026 10:55:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/10/2026 12:45:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 13h 50m
FlixBus	17h 20m	1:40 PM	Luxembourg City	P+R Bouillon	7:00 AM	Prague	Wilsonova Bus Station	Economy	$33	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/9/2026 1:40:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/10/2026 7:00:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 17h 20m
FlixBus	16h 15m	7:15 PM	Luxembourg City	P+R Bouillon	11:30 AM	Prague	Wilsonova Bus Station	Economy	$33	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/9/2026 7:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/10/2026 11:30:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 16h 15m
FlixBus	12h 0m	10:55 AM	Luxembourg City	P+R Bouillon	10:55 PM	Prague	Na Knížecí Station	Economy	$33	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/9/2026 10:55:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/9/2026 10:55:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 12h 0m
FlixBus	12h 15m	10:55 AM	Luxembourg City	P+R Bouillon	11:10 PM	Prague	ÚAN Florenc	Economy	$33	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/9/2026 10:55:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/9/2026 11:10:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 12h 15m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 0m	10:55 AM	Luxembourg City	P+R Bouillon	10:55 PM	Prague	Na Knížecí Station	Economy	$49	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/11/2026 10:55:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/11/2026 10:55:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 12h 0m
FlixBus	12h 15m	10:55 AM	Luxembourg City	P+R Bouillon	11:10 PM	Prague	ÚAN Florenc	Economy	$49	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/11/2026 10:55:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/11/2026 11:10:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 12h 15m
FlixBus	16h 5m	7:15 PM	Luxembourg City	P+R Bouillon	11:20 AM	Prague	Wilsonova Bus Station	Economy	$50	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/11/2026 7:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/12/2026 11:20:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 16h 5m
FlixBus	16h 15m	7:15 PM	Luxembourg City	P+R Bouillon	11:30 AM	Prague	Wilsonova Bus Station	Economy	$50	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/11/2026 7:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/12/2026 11:30:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 16h 15m
FlixBus	15h 5m	6:05 AM	Luxembourg City	P+R Bouillon	9:10 PM	Prague	Na Knížecí Station	Economy	$50	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/11/2026 6:05:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/11/2026 9:10:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 15h 5m

Did you know that if you travel from Luxembourg City to Prague via Frankfurt am Main, you can save more than $5? You can find the corresponding connections below.
- FlixBus
  
  11h 55m
  
  0
  
  1:35 AM
  
  Luxembourg City
  P+R Bouillon
  
  5:25 AM
  
  Frankfurt am Main
  Central Station
  
  0
  
  Economy
  
  $17
  
  A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/10/2026 1:35:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 9/10/2026 5:25:00 AM. 50 Economy ticket for $17 per person are available. Travel duration is 3h 50m
- FlixBus
  
  7h 25m
  
  0
  
  6:05 AM
  
  Frankfurt am Main
  Central Station
  
  1:30 PM
  
  Prague
  ÚAN Florenc
  
  0
  
  Economy
  
  $27
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 9/10/2026 6:05:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/10/2026 1:30:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 7h 25m
Travel Time is 0h 5m shorter, and you will save $5

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	15h 25m	2:05 AM	Luxembourg City	P+R Bouillon	5:30 PM	Prague	Wilsonova Bus Station	Economy	$42	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/13/2026 2:05:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/13/2026 5:30:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 15h 25m
FlixBus	13h 20m	2:40 AM	Luxembourg City	P+R Bouillon	4:00 PM	Prague	Wilsonova Bus Station	Economy	$42	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/13/2026 2:40:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/13/2026 4:00:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 13h 20m
FlixBus	16h 5m	7:15 PM	Luxembourg City	P+R Bouillon	11:20 AM	Prague	Wilsonova Bus Station	Economy	$42	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/13/2026 7:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/14/2026 11:20:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 16h 5m
FlixBus	16h 15m	7:15 PM	Luxembourg City	P+R Bouillon	11:30 AM	Prague	Wilsonova Bus Station	Economy	$42	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/13/2026 7:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/14/2026 11:30:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 16h 15m
FlixBus	13h 0m	2:40 AM	Luxembourg City	P+R Bouillon	3:40 PM	Prague	ÚAN Florenc	Economy	$42	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/13/2026 2:40:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/13/2026 3:40:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 13h 0m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	16h 5m	7:15 PM	Luxembourg City	P+R Bouillon	11:20 AM	Prague	Wilsonova Bus Station	Economy	$28	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/15/2026 7:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 9/16/2026 11:20:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 16h 5m
FlixBus	16h 30m	2:40 AM	Luxembourg City	P+R Bouillon	7:10 PM	Prague	Na Knížecí Station	Economy	$28	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/15/2026 2:40:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/15/2026 7:10:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 16h 30m
FlixBus	15h 35m	5:20 PM	Luxembourg City	P+R Bouillon	8:55 AM	Prague	Na Knížecí Station	Economy	$28	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/15/2026 5:20:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/16/2026 8:55:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 15h 35m
FlixBus	14h 50m	7:15 PM	Luxembourg City	P+R Bouillon	10:05 AM	Prague	Na Knížecí Station	Economy	$28	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/15/2026 7:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 9/16/2026 10:05:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 14h 50m
FlixBus	16h 10m	5:00 AM	Luxembourg City	P+R Bouillon	9:10 PM	Prague	ÚAN Florenc	Economy	$28	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 9/15/2026 5:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 9/15/2026 9:10:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 16h 10m

Best Price Offer: The price for the cheapest bus from Luxembourg City to Prague is $27 on 9/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Luxembourg City and Prague

See here how frequent the connections between Luxembourg City and Prague are, during different times and days of the week.

Friday is the busiest day, with more than 24 daily buses from Luxembourg City to Prague. Wednesday has instead the fewest connections, with only 9 daily coaches between Luxembourg City and Prague.

The busiest time of the day is the Night, with 27 buses from Luxembourg City to Prague, while Afternoon sees the fewest connections between Luxembourg City and Prague, with 12 offers.

Facts about the bus from Luxembourg City to Prague

Compare all providers like FlixBus that travel 19 times every day by bus from Luxembourg City to Prague in one click! Book your bus ticket from Luxembourg City to Prague starting from $27!

Cheapest Bus	$27
Fastest Bus	11h 40m
Earliest Bus	10:55 AM
Latest Bus	7:15 PM
Daily Bus Routes	19 Ø
Distance	371.4 miles
Bus Companies	FlixBus

Cheapest bus connections from Luxembourg City to Prague

Every day, 19 buses from 1 bus companies leave Luxembourg City for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/09/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

Wednesday 09/09

$33

Thursday 09/10

Friday 09/11

$49

Saturday 09/12

$43

Sunday 09/13

$42

Monday 09/14

Tuesday 09/15

$28

Wednesday 09/16

Thursday 09/17

$38

Friday 09/18

Saturday 09/19

$43

Sunday 09/20

Monday 09/21

$31

Tuesday 09/22

$27

Wednesday 09/23

Thursday 09/24

Friday 09/25

Saturday 09/26

$39

Sunday 09/27

$67

Monday 09/28

$40

Tuesday 09/29

Wednesday 09/30

Thursday 10/01

Friday 10/02

Saturday 10/03

The cheapest time to travel from Luxembourg City to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Luxembourg City to Prague, for the next 30 days.

With a price starting from $27, Tuesday is the cheapest day for a bus from Luxembourg City to Prague. Friday instead is the most expensive day with prices starting from $49.

Night is the cheapest day time for bus tickets from Luxembourg City to Prague, with $27. Morning is the most expensive time of the day with prices starting from $28.

How to save money travelling from Luxembourg City to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Luxembourg City to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Luxembourg City to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Luxembourg City to Prague are also emptier.

All bus stations and stops in Luxembourg City and Prague

In the map below, you can see where to find all bus stations in Luxembourg City and Prague.

Central Bus Station

Place de la Gare

P+R Bouillon

Rue de Bouillon

Bus Stop

Rue Mercier 2

Limpertsberg

Avenue de la Faïencerie

Gasperich

Rue In Bouler 1

Na Knížecí Station

Za Ženskými domovy / Ostrovského

ÚAN Florenc

Křižíkova 279

Wilsonova Bus Station

Wilsonova 300/8

Roztyly

Tomíčkova 2234

Hradčanská

Milady Horákové 115/107

Service and Comfort on the bus from Luxembourg City to Prague

Want to know which seat classes are available on the buses from Luxembourg City to Prague? Or which bus companies serve the route Luxembourg City to Prague? Below you will find answers to your questions.

FAQs about the Luxembourg City to Prague bus

How much does a Luxembourg City Prague bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $27 and takes 16h 5m to reach Prague. Compare offers to save money!

How much could I save by comparing buses from Luxembourg City to Prague?

This route is offered by 1 companies with a range of ticket prices between $27 and $64. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Prague.

On average, how many connections are available from Luxembourg City to Prague each day?

Every day, the Luxembourg City to Prague bus route is served by approximately 19 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Luxembourg City to Prague take?

The fastest bus from Luxembourg City to Prague is offered by FlixBus and takes 11h 40m. Bus tickets for this connection cost $47. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Luxembourg City to Prague?

The earliest bus arriving in Prague from Luxembourg City starts at 10:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Luxembourg City to Prague?

The latest bus trip departing from Luxembourg City for Prague starts at 7:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Luxembourg City Prague route?

When traveling by bus from Luxembourg City to Prague, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Luxembourg City and Prague?

You can check all the direct connections between Luxembourg City and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Luxembourg City to Prague bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Luxembourg City Prague bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Luxembourg City Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Luxembourg City to Prague on your planned travel date.

Available seat classes which are offered on the bus route Luxembourg City to Prague

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Luxembourg City and to Prague

Here’s an overview of the most popular bus routes to Luxembourg City and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!