Bus Florence, SC to Madison, WI - Compare all Companies

Compare all timetables for the bus from Florence, SC to Madison, WI

Here is a selection of the cheapest bus trips from the schedule from Florence, SC to Madison, WI from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

Monday

$138

Tuesday

$143

Wednesday

Thursday

$137

Friday

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 25m	12:10 PM	Florence, SC	Bus Station	3:35 PM	Madison, WI	Dutch Mill Park & Ride	Economy	$138	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 7/27/2026 12:10:00 PM to Dutch Mill Park & Ride, Madison, WI (USA) arriving at 7/28/2026 3:35:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 28h 25m
Greyhound US	28h 40m	12:10 PM	Florence, SC	Bus Station	3:50 PM	Madison, WI	Chazen Museum	Economy	$139	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 7/27/2026 12:10:00 PM to Chazen Museum, Madison, WI (USA) arriving at 7/28/2026 3:50:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 28h 40m
FlixBus	45h 10m	4:15 PM	Florence, SC	Bus Station	12:25 PM	Madison, WI	Dutch Mill Park & Ride	Economy	$265	A Bus from FlixBus goes from Bus Station, Florence, SC (USA) at 7/27/2026 4:15:00 PM to Dutch Mill Park & Ride, Madison, WI (USA) arriving at 7/29/2026 12:25:00 PM. 50 Economy ticket for $265 per person are available. Travel duration is 45h 10m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	31h 10m	12:10 PM	Florence, SC	Bus Station	6:20 PM	Madison, WI	Chazen Museum	Economy	$143	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 7/28/2026 12:10:00 PM to Chazen Museum, Madison, WI (USA) arriving at 7/29/2026 6:20:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 31h 10m
Greyhound US	42h 25m	7:00 PM	Florence, SC	Bus Station	12:25 PM	Madison, WI	Dutch Mill Park & Ride	Economy	$218	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 7/28/2026 7:00:00 PM to Dutch Mill Park & Ride, Madison, WI (USA) arriving at 7/30/2026 12:25:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 42h 25m
FlixBus	37h 20m	12:05 AM	Florence, SC	TA Travel Center	12:25 PM	Madison, WI	W Transfer Point	Economy	$247	A Bus from FlixBus goes from TA Travel Center, Florence, SC (USA) at 7/28/2026 12:05:00 AM to W Transfer Point, Madison, WI (USA) arriving at 7/29/2026 12:25:00 PM. 50 Economy ticket for $247 per person are available. Travel duration is 37h 20m
FlixBus	37h 40m	12:05 AM	Florence, SC	TA Travel Center	12:45 PM	Madison, WI	University Wisconsin-Madison	Economy	$247	A Bus from FlixBus goes from TA Travel Center, Florence, SC (USA) at 7/28/2026 12:05:00 AM to University Wisconsin-Madison, Madison, WI (USA) arriving at 7/29/2026 12:45:00 PM. 50 Economy ticket for $247 per person are available. Travel duration is 37h 40m

Did you know that if you travel from Florence, SC to Madison, WI via Chicago, you can save more than $17? You can find the corresponding connections below.
- Greyhound US
  
  28h 40m
  
  0
  
  11:55 AM
  
  Florence, SC
  Bus Station
  
  11:30 AM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $104
  
  A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 7/29/2026 11:55:00 AM to Downtown Bus Station, Chicago (USA) arriving at 7/30/2026 11:30:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 24h 35m
- FlixBus
  
  3h 5m
  
  0
  
  12:30 PM
  
  Chicago
  Downtown Bus Station
  
  3:35 PM
  
  Madison, WI
  Dutch Mill Park & Ride
  
  0
  
  Economy
  
  $22
  
  A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 7/30/2026 12:30:00 PM to Dutch Mill Park & Ride, Madison, WI (USA) arriving at 7/30/2026 3:35:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 3h 5m
Travel Time is 1h 30m shorter, and you will save $17

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 25m	12:10 PM	Florence, SC	Bus Station	3:35 PM	Madison, WI	W Transfer Point	Economy	$137	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 7/30/2026 12:10:00 PM to W Transfer Point, Madison, WI (USA) arriving at 7/31/2026 3:35:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 28h 25m
Greyhound US	28h 40m	12:10 PM	Florence, SC	Bus Station	3:50 PM	Madison, WI	University Wisconsin-Madison	Economy	$138	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 7/30/2026 12:10:00 PM to University Wisconsin-Madison, Madison, WI (USA) arriving at 7/31/2026 3:50:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 28h 40m
FlixBus	31h 40m	5:45 AM	Florence, SC	TA Travel Center	12:25 PM	Madison, WI	W Transfer Point	Economy	$145	A Bus from FlixBus goes from TA Travel Center, Florence, SC (USA) at 7/30/2026 5:45:00 AM to W Transfer Point, Madison, WI (USA) arriving at 7/31/2026 12:25:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 31h 40m
FlixBus	32h 0m	5:45 AM	Florence, SC	TA Travel Center	12:45 PM	Madison, WI	University Wisconsin-Madison	Economy	$145	A Bus from FlixBus goes from TA Travel Center, Florence, SC (USA) at 7/30/2026 5:45:00 AM to University Wisconsin-Madison, Madison, WI (USA) arriving at 7/31/2026 12:45:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 32h 0m
Greyhound US	42h 25m	7:00 PM	Florence, SC	Bus Station	12:25 PM	Madison, WI	W Transfer Point	Economy	$225	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 7/30/2026 7:00:00 PM to W Transfer Point, Madison, WI (USA) arriving at 8/1/2026 12:25:00 PM. 50 Economy ticket for $225 per person are available. Travel duration is 42h 25m

Best Price Offer: The price for the cheapest bus from Florence, SC to Madison, WI is $126 on 8/6/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Florence, SC and Madison, WI

See here how frequent the connections between Florence, SC and Madison, WI are, during different times and days of the week.

Tuesday is the busiest day, with more than 6 daily buses from Florence, SC to Madison, WI. Monday has instead the fewest connections, with only 3 daily coaches between Florence, SC and Madison, WI.

The busiest time of the day is the Afternoon, with 7 buses from Florence, SC to Madison, WI, while Evening sees the fewest connections between Florence, SC and Madison, WI, with 3 offers.

Facts about the bus from Florence, SC to Madison, WI

Compare all providers like Greyhound US and FlixBus that travel 4 times every day by bus from Florence, SC to Madison, WI in one click! Book your bus ticket from Florence, SC to Madison, WI starting from $126!

Cheapest Bus	$126
Fastest Bus	27h 25m
Earliest Bus	12:10 PM
Latest Bus	7:00 PM
Daily Bus Routes	4 Ø
Distance	803.5 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Florence, SC to Madison, WI

Every day, 4 buses from 2 bus companies leave Florence, SC for Madison, WI: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

Friday 07/24

Saturday 07/25

Sunday 07/26

Monday 07/27

$127

Tuesday 07/28

$147

Wednesday 07/29

Thursday 07/30

$137

Friday 07/31

Saturday 08/01

Sunday 08/02

$147

Monday 08/03

$173

Tuesday 08/04

Wednesday 08/05

Thursday 08/06

$126

Friday 08/07

Saturday 08/08

$126

Sunday 08/09

$150

Monday 08/10

Tuesday 08/11

$143

Wednesday 08/12

$142

Thursday 08/13

Friday 08/14

Saturday 08/15

The cheapest time to travel from Florence, SC to Madison, WI

See here on which day and which time of the day you can find the cheapest bus ticket from Florence, SC to Madison, WI, for the next 30 days.

With a price starting from $126, Thursday is the cheapest day for a bus from Florence, SC to Madison, WI. Tuesday instead is the most expensive day with prices starting from $143.

Night is the cheapest day time for bus tickets from Florence, SC to Madison, WI, with $126. Evening is the most expensive time of the day with prices starting from $218.

How to save money travelling from Florence, SC to Madison, WI

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Florence, SC to Madison, WI in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Florence, SC to Madison, WI, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Florence, SC to Madison, WI are also emptier.

All bus stations and stops in Florence, SC and Madison, WI

In the map below, you can see where to find all bus stations in Florence, SC and Madison, WI.

Bus Station

S Irby St 611

TA Travel Center

W Lucas St 2301

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

Dutch Mill Park & Ride

E Broadway

University Wisconsin-Madison

North Lake Street 200

Bus Stop

Memorial Union Building

Langdon Street 800

Chazen Museum

University Avenue 750-800

Service and Comfort on the bus from Florence, SC to Madison, WI

Want to know which seat classes are available on the buses from Florence, SC to Madison, WI? Or which bus companies serve the route Florence, SC to Madison, WI? Below you will find answers to your questions.

FAQs about the Florence, SC to Madison, WI bus

How much does a Florence, SC Madison, WI bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $126 and takes 27h 25m to reach Madison, WI. Compare offers to save money!

How much could I save by comparing buses from Florence, SC to Madison, WI?

This route is offered by 2 companies with a range of ticket prices between $126 and $265. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Madison, WI.

On average, how many connections are available from Florence, SC to Madison, WI each day?

Every day, the Florence, SC to Madison, WI bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Florence, SC to Madison, WI take?

The fastest bus from Florence, SC to Madison, WI is offered by Greyhound US and takes 27h 25m. Bus tickets for this connection cost $138. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Florence, SC to Madison, WI?

The earliest bus arriving in Madison, WI from Florence, SC starts at 12:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Florence, SC to Madison, WI?

The latest bus trip departing from Florence, SC for Madison, WI starts at 7:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Florence, SC Madison, WI route?

When traveling by bus from Florence, SC to Madison, WI, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Florence, SC and Madison, WI?

You can check all the direct connections between Florence, SC and Madison, WI by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Florence, SC to Madison, WI bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Florence, SC Madison, WI bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Florence, SC Madison, WI bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Florence, SC to Madison, WI on your planned travel date.

Available seat classes which are offered on the bus route Florence, SC to Madison, WI

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Florence, SC and to Madison, WI

Here’s an overview of the most popular bus routes to Florence, SC and to Madison, WI. Simply click on the connection of your choice, and you will find all the details about your bus route!