Which bus from Cambridge, MA to Florence, SC is the cheapest?

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Compare all timetables for the bus from Cambridge, MA to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Cambridge, MA to Florence, SC from various bus operators like FlixBus for the next days.

today
tomorrow
Saturday
$118
Sunday
$120
Monday
$100
Tuesday
$108
Wednesday
$112

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 10m 11:00 AM Cambridge, MA Alewife Station 9:10 AM Florence, SC Bus Station  Economy $118
  • Did you know that if you travel from Cambridge, MA to Florence, SC via Washington, DC, you can save more than $14? You can find the corresponding connections below.
    • FlixBus
      22h 10m
      0
      11:00 AM
      Cambridge, MA
      Alewife Station
      11:30 PM
      Washington, DC
      Union Station
      0
      FlixBus
      Economy
      $51
      • Waiting Time 0h 15m
    • Greyhound US
      9h 25m
      0
      11:45 PM
      Washington, DC
      Union Station
      9:10 AM
      Florence, SC
      Bus Station
      0
      Greyhound US
      Economy
      $53
    Travel time is the same as the direct connection, but you will save $14

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 10m 11:00 AM Cambridge, MA Alewife Station 9:10 AM Florence, SC Bus Station  Economy $120
  • Did you know that if you travel from Cambridge, MA to Florence, SC via Washington, DC, you can save more than $16? You can find the corresponding connections below.
    • FlixBus
      22h 10m
      0
      11:00 AM
      Cambridge, MA
      Alewife Station
      11:30 PM
      Washington, DC
      Union Station
      0
      FlixBus
      Economy
      $51
      • Waiting Time 0h 15m
    • Greyhound US
      9h 25m
      0
      11:45 PM
      Washington, DC
      Union Station
      9:10 AM
      Florence, SC
      Bus Station
      0
      Greyhound US
      Economy
      $53
    Travel time is the same as the direct connection, but you will save $16

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 10m 11:00 AM Cambridge, MA Alewife Station 9:10 AM Florence, SC Bus Station  Economy $100

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 37h 5m 11:00 AM Cambridge, MA Alewife Station 12:05 AM Florence, SC TA Travel Center  Economy $108
FlixBus 22h 10m 11:00 AM Cambridge, MA Alewife Station 9:10 AM Florence, SC Bus Station  Economy $108

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 37h 5m 11:00 AM Cambridge, MA Alewife Station 12:05 AM Florence, SC TA Travel Center  Economy $112
FlixBus 22h 10m 11:00 AM Cambridge, MA Alewife Station 9:10 AM Florence, SC Bus Station  Economy $112
  • Did you know that if you travel from Cambridge, MA to Florence, SC via Washington, DC, you can save more than $14? You can find the corresponding connections below.
    • FlixBus
      22h 10m
      0
      11:00 AM
      Cambridge, MA
      Alewife Station
      11:30 PM
      Washington, DC
      Union Station
      0
      FlixBus
      Economy
      $45
      • Waiting Time 1h 50m
    • Greyhound US
      7h 50m
      0
      1:20 AM
      Washington, DC
      Union Station
      9:10 AM
      Florence, SC
      Bus Station
      0
      Greyhound US
      Economy
      $53
    Travel time is the same as the direct connection, but you will save $14

Best Price Offer: The price for the cheapest bus from Cambridge, MA to Florence, SC is $86 on 8/12/2026. Flexible travelers save on ticket prices.


Facts about the bus from Cambridge, MA to Florence, SC

Compare all providers like FlixBus that travel 1 times every day by bus from Cambridge, MA to Florence, SC in one click! Book your bus ticket from Cambridge, MA to Florence, SC starting from $86!

Cheapest Bus $86
Fastest Bus 22h 10m
Earliest Bus 11:00 AM
Latest Bus 11:00 AM
Daily Bus Routes 1 Ø
Distance 733.9 miles
Bus Companies FlixBus

Cheapest bus connections from Cambridge, MA to Florence, SC

Every day, 1 buses from 1 bus companies leave Cambridge, MA for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/23/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/19
Monday 07/20
Tuesday 07/21
Wednesday 07/22
Thursday 07/23
Friday 07/24
Saturday 07/25
$118
Sunday 07/26
$116
Monday 07/27
$100
Tuesday 07/28
$108
Wednesday 07/29
$112
Thursday 07/30
Friday 07/31
$114
Saturday 08/01
Sunday 08/02
Monday 08/03
Tuesday 08/04
Wednesday 08/05
$102
Thursday 08/06
Friday 08/07
$108
Saturday 08/08
$110
Sunday 08/09
$102
Monday 08/10
$98
Tuesday 08/11
$102
Wednesday 08/12
$86
Thursday 08/13
Friday 08/14
Saturday 08/15

How to save money travelling from Cambridge, MA to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Cambridge, MA to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Cambridge, MA to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Cambridge, MA to Florence, SC are also emptier.

All bus stations and stops in Cambridge, MA and Florence, SC

In the map below, you can see where to find all bus stations in Cambridge, MA and Florence, SC.

Service and Comfort on the bus from Cambridge, MA to Florence, SC

Want to know which seat classes are available on the buses from Cambridge, MA to Florence, SC? Or which bus companies serve the route Cambridge, MA to Florence, SC? Below you will find answers to your questions.

FAQs about the Cambridge, MA to Florence, SC bus

How much does a Cambridge, MA Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $86 and takes 22h 10m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Cambridge, MA to Florence, SC?

This route is offered by 1 companies with a range of ticket prices between $86 and $120. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Cambridge, MA to Florence, SC each day?

Every day, the Cambridge, MA to Florence, SC bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Cambridge, MA to Florence, SC take?

The fastest bus from Cambridge, MA to Florence, SC is offered by FlixBus and takes 22h 10m. Bus tickets for this connection cost $118. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Cambridge, MA to Florence, SC?

The earliest bus arriving in Florence, SC from Cambridge, MA starts at 11:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Cambridge, MA to Florence, SC?

The latest bus trip departing from Cambridge, MA for Florence, SC starts at 11:00 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Cambridge, MA Florence, SC route?

When traveling by bus from Cambridge, MA to Florence, SC, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Cambridge, MA and Florence, SC?

You can check all the direct connections between Cambridge, MA and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Cambridge, MA to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Cambridge, MA Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Cambridge, MA Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Cambridge, MA to Florence, SC on your planned travel date.

Available seat classes which are offered on the bus route Cambridge, MA to Florence, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Cambridge, MA and to Florence, SC

Here’s an overview of the most popular bus routes to Cambridge, MA and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Cambridge, MA and to Florence, SC
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