Bus from Tampa to Knoxville, TN from $109

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Compare all timetables for the bus from Tampa to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Tampa to Knoxville, TN from various bus operators like FlixBus for the next days.
today
$145
tomorrow
$161
Tuesday
Wednesday
Thursday
Friday
$134
Saturday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 25m 10:25 PM Tampa USF 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $145
FlixBus 23h 15m 10:35 PM Tampa Marion Street 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $145
  • Did you know that if you travel from Tampa to Knoxville, TN via Atlanta, GA, you can save more than $46? You can find the corresponding connections below.
    • FlixBus
      28h 25m
      0
      5:25 PM
      Tampa
      USF
      7:40 AM
      Atlanta, GA
      Civic Center MARTA Station
      0
      FlixBus
      Economy
      $60
      • Waiting Time 10h 25m
    • Greyhound US
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $39
    Travel time is 5h 10m longer, but you will save $46

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 25m 10:25 PM Tampa USF 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $161
FlixBus 23h 15m 10:35 PM Tampa Marion Street 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $161
  • Did you know that if you travel from Tampa to Knoxville, TN via Atlanta, GA, you can save more than $62? You can find the corresponding connections below.
    • FlixBus
      28h 25m
      0
      5:25 PM
      Tampa
      USF
      7:40 AM
      Atlanta, GA
      Civic Center MARTA Station
      0
      FlixBus
      Economy
      $60
      • Waiting Time 10h 25m
    • Greyhound US
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $39
    Travel time is 5h 10m longer, but you will save $62

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 25m 10:25 PM Tampa USF 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $134
FlixBus 23h 15m 10:35 PM Tampa Marion Street 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $134
  • Did you know that if you travel from Tampa to Knoxville, TN via Atlanta, GA, you can save more than $35? You can find the corresponding connections below.
    • FlixBus
      28h 25m
      0
      5:25 PM
      Tampa
      USF
      7:40 AM
      Atlanta, GA
      Civic Center MARTA Station
      0
      FlixBus
      Economy
      $60
      • Waiting Time 10h 25m
    • Greyhound US
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $39
    Travel time is 5h 10m longer, but you will save $35

Test cheapest views

The cheapest bus for the 8/3/2026 costs just $109, from FlixBus

Facts about the bus from Tampa to Knoxville, TN

Compare all providers like FlixBus that travel 2 times every day by bus from Tampa to Knoxville, TN in one click! Book your bus ticket from Tampa to Knoxville, TN starting from $109!

Cheapest Bus $109
Fastest Bus 23h 15m
Earliest Bus 10:25 PM
Latest Bus 10:35 PM
Daily Bus Routes 2 Ø
Distance 560.1 miles
Bus Companies FlixBus

Cheapest bus connections from Tampa to Knoxville, TN

Every day, 2 buses from 1 bus companies leave Tampa for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/26
$145
Monday 07/27
$161
Tuesday 07/28
Wednesday 07/29
Thursday 07/30
$128
Friday 07/31
$134
Saturday 08/01
Sunday 08/02
Monday 08/03
$109
Tuesday 08/04
Wednesday 08/05
Thursday 08/06
$110
Friday 08/07
Saturday 08/08
Sunday 08/09
Monday 08/10
Tuesday 08/11
Wednesday 08/12
$125
Thursday 08/13
$127
Friday 08/14
Saturday 08/15
Sunday 08/16
Monday 08/17
Tuesday 08/18
Wednesday 08/19
Thursday 08/20
Friday 08/21
Saturday 08/22

How to save money travelling from Tampa to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tampa to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tampa to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tampa to Knoxville, TN are also emptier.

All bus stations and stops in Tampa and Knoxville, TN

In the map below, you can see where to find all bus stations in Tampa and Knoxville, TN.

Service and Comfort on the bus from Tampa to Knoxville, TN

Want to know which seat classes are available on the buses from Tampa to Knoxville, TN? Or which bus companies serve the route Tampa to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Tampa to Knoxville, TN bus

How much does a Tampa Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $109 and takes 23h 25m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Tampa to Knoxville, TN?

This route is offered by 1 companies with a range of ticket prices between $109 and $161. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Tampa to Knoxville, TN each day?

Every day, the Tampa to Knoxville, TN bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tampa to Knoxville, TN take?

The fastest bus from Tampa to Knoxville, TN is offered by FlixBus and takes 23h 15m. Bus tickets for this connection cost $145. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tampa to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Tampa starts at 10:25 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tampa to Knoxville, TN?

The latest bus trip departing from Tampa for Knoxville, TN starts at 10:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tampa Knoxville, TN route?

When traveling by bus from Tampa to Knoxville, TN, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tampa and Knoxville, TN?

You can check all the direct connections between Tampa and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Tampa to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tampa Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tampa Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tampa to Knoxville, TN on your planned travel date.

Available seat classes which are offered on the bus route Tampa to Knoxville, TN

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tampa and to Knoxville, TN

Here’s an overview of the most popular bus routes to Tampa and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
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