Bus from Santiago, RM to Antofagasta from $31

Compare 8 companies and find the best price with CheckMyBus
Search for your destination Millions of deals worldwide
Compare results Save up to 70%
Find the right bus for you Easy and transparent

Compare all timetables for the bus from Santiago, RM to Antofagasta

Here is a selection of the cheapest bus trips from the schedule from Santiago, RM to Antofagasta from various bus operators like Pullman San Andres, Pluss Chile or Cikbus Elité for the next days.
today
$32
tomorrow
$32
Wednesday
$34
Thursday
$34
Friday
$33
Saturday
$32
Sunday
$36

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 35m 12:15 PM Santiago, RM Terminal San Borja 6:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $32
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $34
Cormar Bus 18h 20m 10:55 PM Santiago, RM Terminal San Borja 5:15 PM Antofagasta Camus Bus Station  Premium Economy $35
Pullman Bus 18h 50m 11:00 AM Santiago, RM Terminal San Borja 5:50 AM Antofagasta Camus Bus Station  First Class $42
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $45

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 17h 45m 11:00 AM Santiago, RM Terminal San Borja 4:45 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $32
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $33
Cormar Bus 18h 20m 10:55 PM Santiago, RM Terminal San Borja 5:15 PM Antofagasta Camus Bus Station  Premium Economy $35
Pluss Chile 18h 10m 7:45 AM Santiago, RM Sur Bus Station 1:55 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $38
Cikbus Elité 19h 0m 7:30 AM Santiago, RM Sur Bus Station 2:30 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $42

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $34
Pluss Chile 18h 10m 7:45 AM Santiago, RM Sur Bus Station 1:55 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $38
Cormar Bus 18h 20m 10:55 PM Santiago, RM Terminal San Borja 5:15 PM Antofagasta Camus Bus Station  Premium Economy $39
Cikbus Elité 19h 0m 7:30 AM Santiago, RM Sur Bus Station 2:30 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $42
Pullman Bus 18h 50m 8:00 AM Santiago, RM Terminal San Borja 2:50 AM Antofagasta Camus Bus Station  First Class $42

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 10m 10:35 AM Santiago, RM Los Libertadores Bus Stop 4:45 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $34
Pluss Chile 18h 10m 7:45 AM Santiago, RM Sur Bus Station 1:55 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $38
Cikbus Elité 19h 0m 7:30 AM Santiago, RM Sur Bus Station 2:30 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $42
Pullman Bus 18h 50m 11:00 AM Santiago, RM Terminal San Borja 5:50 AM Antofagasta Camus Bus Station  First Class $42
Cormar Bus 18h 40m 12:00 PM Santiago, RM Terminal San Borja 6:40 AM Antofagasta Camus Bus Station  Premium Economy $42

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 35m 12:15 PM Santiago, RM Terminal San Borja 6:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $33
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $34
Cormar Bus 18h 20m 10:55 PM Santiago, RM Terminal San Borja 5:15 PM Antofagasta Camus Bus Station  Premium Economy $39
Pullman Bus 18h 50m 11:00 AM Santiago, RM Terminal San Borja 5:50 AM Antofagasta Camus Bus Station  First Class $42
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $45

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $32
FlixBus 18h 45m 6:50 AM Santiago, RM Los Libertadores Bus Stop 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $39
Cormar Bus 18h 40m 12:00 PM Santiago, RM Terminal San Borja 6:40 AM Antofagasta Camus Bus Station  Premium Economy $39
Pullman Bus 18h 50m 11:00 AM Santiago, RM Terminal San Borja 5:50 AM Antofagasta Camus Bus Station  First Class $42
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $45

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 45m 11:00 AM Santiago, RM Terminal San Borja 4:45 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $36
Cormar Bus 18h 20m 10:55 PM Santiago, RM Terminal San Borja 5:15 PM Antofagasta Camus Bus Station  Premium Economy $39
Pullman Bus 18h 50m 11:00 AM Santiago, RM Terminal San Borja 5:50 AM Antofagasta Camus Bus Station  First Class $42
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $45
Gentour 16h 30m 1:45 PM Santiago, RM Terminal San Borja 6:15 AM Antofagasta Maipú  Premium Economy $47

Frequency of bus connections between Santiago, RM and Antofagasta

See here how frequent the connections between Santiago, RM and Antofagasta are, during different times and days of the week.
Monday is the busiest day, with more than 122 daily buses from Santiago, RM to Antofagasta. Saturday has instead the fewest connections, with only 43 daily coaches between Santiago, RM and Antofagasta.
The busiest time of the day is the Morning, with 184 buses from Santiago, RM to Antofagasta, while Evening sees the fewest connections between Santiago, RM and Antofagasta, with 169 offers.

Test cheapest views

The cheapest bus for the 7/28/2026 costs just $31, from Nueva Andimar Vip

Facts about the bus from Santiago, RM to Antofagasta

Compare all providers like Pullman San Andres, Pluss Chile and Cikbus Elité that travel 74 times every day by bus from Santiago, RM to Antofagasta in one click! Book your bus ticket from Santiago, RM to Antofagasta starting from $31!

Cheapest Bus $31
Fastest Bus 15h 40m
Earliest Bus 6:50 AM
Latest Bus 11:30 PM
Daily Bus Routes 74 Ø
Distance 677.0 miles
Bus Companies Pullman San Andres, Pluss Chile, Cikbus Elité, FlixBus, Pullman Bus, Cormar Bus, Nueva Andimar Vip and Gentour

Cheapest bus connections from Santiago, RM to Antofagasta

Every day, 74 buses from 8 bus companies leave Santiago, RM for Antofagasta: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/26
Monday 07/27
$31
Tuesday 07/28
$31
Wednesday 07/29
$31
Thursday 07/30
$43
Friday 07/31
$31
Saturday 08/01
$36
Sunday 08/02
$37
Monday 08/03
$35
Tuesday 08/04
$34
Wednesday 08/05
$35
Thursday 08/06
$35
Friday 08/07
$38
Saturday 08/08
$35
Sunday 08/09
$37
Monday 08/10
$35
Tuesday 08/11
$34
Wednesday 08/12
$35
Thursday 08/13
$36
Friday 08/14
$39
Saturday 08/15
$38
Sunday 08/16
$38
Monday 08/17
$37
Tuesday 08/18
$34
Wednesday 08/19
$33
Thursday 08/20
$34
Friday 08/21
$35
Saturday 08/22

The cheapest time to travel from Santiago, RM to Antofagasta

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago, RM to Antofagasta, for the next 30 days.
With a price starting from $31, Tuesday is the cheapest day for a bus from Santiago, RM to Antofagasta. Sunday instead is the most expensive day with prices starting from $36.
Morning is the cheapest day time for bus tickets from Santiago, RM to Antofagasta, with $32. Evening is the most expensive time of the day with prices starting from $35.

How to save money travelling from Santiago, RM to Antofagasta

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago, RM to Antofagasta in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to Antofagasta, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago, RM to Antofagasta are also emptier.

Latest reviews for bus companies on the route Santiago, RM - Antofagasta

Gentour
German Burgos, 9/1/2025
Bus con muy mal olor, sube gente tomando y fuman en los baños asientos incómodos. Super malo el servicio dejan a las personas fuera de los terminales en la calle. El bus no entra a los terminales. Pa ... Bus con muy mal olor, sube gente tomando y fuman en los baños asientos incómodos. Super malo el servicio dejan a las personas fuera de los terminales en la calle. El bus no entra a los terminales. Para nunca más con Gentour.

All bus stations and stops in Santiago, RM and Antofagasta

In the map below, you can see where to find all bus stations in Santiago, RM and Antofagasta.

Service and Comfort on the bus from Santiago, RM to Antofagasta

Want to know which seat classes are available on the buses from Santiago, RM to Antofagasta? Or which bus companies serve the route Santiago, RM to Antofagasta? Below you will find answers to your questions.

FAQs about the Santiago, RM to Antofagasta bus

How much does a Santiago, RM Antofagasta bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $31 and takes 17h 45m to reach Antofagasta. Compare offers to save money!

How much could I save by comparing buses from Santiago, RM to Antofagasta?

This route is offered by 8 companies with a range of ticket prices between $31 and $74. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Antofagasta.

On average, how many connections are available from Santiago, RM to Antofagasta each day?

Every day, the Santiago, RM to Antofagasta bus route is served by approximately 74 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago, RM to Antofagasta take?

The fastest bus from Santiago, RM to Antofagasta is offered by Pullman San Andres and takes 15h 40m. Bus tickets for this connection cost $52. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago, RM to Antofagasta?

The earliest bus arriving in Antofagasta from Santiago, RM starts at 6:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago, RM to Antofagasta?

The latest bus trip departing from Santiago, RM for Antofagasta starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago, RM Antofagasta route?

When traveling by bus from Santiago, RM to Antofagasta, passengers can travel with Pullman San Andres, Pluss Chile and Cikbus Elité. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago, RM and Antofagasta?

You can check all the direct connections between Santiago, RM and Antofagasta by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pullman San Andres, Pluss Chile and Cikbus Elité.

What can I take with me on the Santiago, RM to Antofagasta bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago, RM Antofagasta bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago, RM Antofagasta bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago, RM to Antofagasta on your planned travel date.

Available seat classes which are offered on the bus route Santiago, RM to Antofagasta

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santiago, RM and to Antofagasta

Here’s an overview of the most popular bus routes to Santiago, RM and to Antofagasta. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses from Cartagena (CL) to Santiago, RM Buses from Cartagena (CL) to Santiago, RM
Buses to Santiago, RM from Graneros Buses to Santiago, RM from Graneros
Bus Collipulli to Santiago, RM Bus Collipulli to Santiago, RM
Bus Concepción to Santiago, RM Bus Concepción to Santiago, RM
Bus San Pedro de Atacama - Antofagasta Bus San Pedro de Atacama - Antofagasta
From Pozo Almonte to Antofagasta bus From Pozo Almonte to Antofagasta bus
Buses to Antofagasta from Los Vilos Buses to Antofagasta from Los Vilos
Buses La Calera to Antofagasta Buses La Calera to Antofagasta
Popular Airport Shuttles to Santiago, RM and to Antofagasta
CheckMyBus › Buses in Chile › Bus to Santiago, RM › Bus to Antofagasta

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.