Bus Prague to Karlsruhe: Compare prices and save money

Compare all timetables for the bus from Prague to Karlsruhe

Here is a selection of the cheapest bus trips from the schedule from Prague to Karlsruhe from various bus operators like FlixBus for the next days.

today

$35

tomorrow

Wednesday

$30

Thursday

Friday

Saturday

Sunday

$40

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 35m	6:40 AM	Prague	ÚAN Florenc	3:15 PM	Karlsruhe	Central Station	Economy	$35	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/7/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 9/7/2026 3:15:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 8h 35m
FlixBus	8h 35m	10:00 PM	Prague	ÚAN Florenc	6:35 AM	Karlsruhe	Central Station	Economy	$36	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/7/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 9/8/2026 6:35:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 8h 35m
FlixBus	8h 10m	10:25 PM	Prague	Hradčanská	6:35 AM	Karlsruhe	Central Station	Economy	$36	A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 9/7/2026 10:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 9/8/2026 6:35:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 8h 10m
FlixBus	8h 40m	3:10 PM	Prague	ÚAN Florenc	11:50 PM	Karlsruhe	Central Station	Economy	$39	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/7/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 9/7/2026 11:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 40m
FlixBus	9h 20m	2:30 PM	Prague	Černý Most	11:50 PM	Karlsruhe	Central Station	Economy	$39	A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 9/7/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 9/7/2026 11:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 9h 20m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	10h 25m	10:55 AM	Prague	Na Knížecí Station	9:20 PM	Karlsruhe	Central Station	Economy	$30	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 9/9/2026 10:55:00 AM to Central Station, Karlsruhe (Germany) arriving at 9/9/2026 9:20:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 10h 25m
FlixBus	8h 45m	3:05 PM	Prague	Zličín	11:50 PM	Karlsruhe	Central Station	Economy	$30	A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 9/9/2026 3:05:00 PM to Central Station, Karlsruhe (Germany) arriving at 9/9/2026 11:50:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 45m
FlixBus	11h 10m	7:25 PM	Prague	Zličín	6:35 AM	Karlsruhe	Central Station	Economy	$30	A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 9/9/2026 7:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 9/10/2026 6:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 11h 10m
FlixBus	11h 25m	2:30 AM	Prague	Wilsonova Bus Station	1:55 PM	Karlsruhe	Central Station	Economy	$31	A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/9/2026 2:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 9/9/2026 1:55:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 11h 25m
FlixBus	9h 55m	5:30 PM	Prague	Wilsonova Bus Station	3:25 AM	Karlsruhe	Central Station	Economy	$31	A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/9/2026 5:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 9/10/2026 3:25:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 9h 55m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 35m	6:40 AM	Prague	ÚAN Florenc	3:15 PM	Karlsruhe	Central Station	Economy	$40	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/13/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 9/13/2026 3:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 8h 35m
FlixBus	8h 35m	10:00 PM	Prague	ÚAN Florenc	6:35 AM	Karlsruhe	Central Station	Economy	$40	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/13/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 9/14/2026 6:35:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 8h 35m
FlixBus	8h 10m	10:25 PM	Prague	Hradčanská	6:35 AM	Karlsruhe	Central Station	Economy	$40	A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 9/13/2026 10:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 9/14/2026 6:35:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 8h 10m
FlixBus	11h 25m	2:30 AM	Prague	Wilsonova Bus Station	1:55 PM	Karlsruhe	Central Station	Economy	$44	A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/13/2026 2:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 9/13/2026 1:55:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 11h 25m
FlixBus	11h 50m	3:25 AM	Prague	Wilsonova Bus Station	3:15 PM	Karlsruhe	Central Station	Economy	$44	A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/13/2026 3:25:00 AM to Central Station, Karlsruhe (Germany) arriving at 9/13/2026 3:15:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 11h 50m

Frequency of bus connections between Prague and Karlsruhe

See here how frequent the connections between Prague and Karlsruhe are, during different times and days of the week.

Sunday is the busiest day, with more than 20 daily buses from Prague to Karlsruhe. Wednesday has instead the fewest connections, with only 16 daily coaches between Prague and Karlsruhe.

The busiest time of the day is the Afternoon, with 18 buses from Prague to Karlsruhe, while Night sees the fewest connections between Prague and Karlsruhe, with 5 offers.

Test cheapest views

The cheapest bus for the 9/9/2026 costs just $30, from FlixBus

Facts about the bus from Prague to Karlsruhe

Compare all providers like FlixBus that travel 17 times every day by bus from Prague to Karlsruhe in one click! Book your bus ticket from Prague to Karlsruhe starting from $30!

Cheapest Bus	$30
Fastest Bus	8h 10m
Earliest Bus	3:40 AM
Latest Bus	11:50 PM
Daily Bus Routes	17 Ø
Distance	280.4 miles
Bus Companies	FlixBus

Cheapest bus connections from Prague to Karlsruhe

Every day, 17 buses from 1 bus companies leave Prague for Karlsruhe: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

$35

Tuesday 09/08

Wednesday 09/09

$30

Thursday 09/10

Friday 09/11

Saturday 09/12

Sunday 09/13

$40

Monday 09/14

Tuesday 09/15

Wednesday 09/16

Thursday 09/17

Friday 09/18

Saturday 09/19

Sunday 09/20

Monday 09/21

Tuesday 09/22

Wednesday 09/23

Thursday 09/24

Friday 09/25

Saturday 09/26

Sunday 09/27

Monday 09/28

Tuesday 09/29

Wednesday 09/30

Thursday 10/01

Friday 10/02

Saturday 10/03

The cheapest time to travel from Prague to Karlsruhe

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Karlsruhe, for the next 30 days.

With a price starting from $30, Wednesday is the cheapest day for a bus from Prague to Karlsruhe. Sunday instead is the most expensive day with prices starting from $40.

Morning is the cheapest day time for bus tickets from Prague to Karlsruhe, with $30. Night is the most expensive time of the day with prices starting from $30.

How to save money travelling from Prague to Karlsruhe

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Karlsruhe in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Karlsruhe, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Karlsruhe are also emptier.

All bus stations and stops in Prague and Karlsruhe

In the map below, you can see where to find all bus stations in Prague and Karlsruhe.

Na Knížecí Station

Za Ženskými domovy / Ostrovského

ÚAN Florenc

Křižíkova 279

Wilsonova Bus Station

Wilsonova 300/8

Roztyly

Tomíčkova 2234

Hradčanská

Milady Horákové 115/107

Central Bus Station

Durlach Auer Str./Dr.Willmar Schwabe Bus Stop

Bannwaldallee Station

Kühler Krug Train Station

Daxlanden Mauerweg Bus Stop

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Karlsruhe? Compare all modes of transports from Prague to Karlsruhe.

Service and Comfort on the bus from Prague to Karlsruhe

Want to know which seat classes are available on the buses from Prague to Karlsruhe? Or which bus companies serve the route Prague to Karlsruhe? Below you will find answers to your questions.

FAQs about the Prague to Karlsruhe bus

How much does a Prague Karlsruhe bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $30 and takes 10h 25m to reach Karlsruhe. Compare offers to save money!

How much could I save by comparing buses from Prague to Karlsruhe?

This route is offered by 1 companies with a range of ticket prices between $30 and $71. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Karlsruhe.

On average, how many connections are available from Prague to Karlsruhe each day?

Every day, the Prague to Karlsruhe bus route is served by approximately 17 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Prague to Karlsruhe take?

The fastest bus from Prague to Karlsruhe is offered by FlixBus and takes 8h 10m. Bus tickets for this connection cost $36. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Prague to Karlsruhe?

The earliest bus arriving in Karlsruhe from Prague starts at 3:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Prague to Karlsruhe?

The latest bus trip departing from Prague for Karlsruhe starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Prague Karlsruhe route?

When traveling by bus from Prague to Karlsruhe, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Prague and Karlsruhe?

You can check all the direct connections between Prague and Karlsruhe by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Prague to Karlsruhe bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Prague Karlsruhe bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Karlsruhe bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Karlsruhe on your planned travel date.

Available seat classes which are offered on the bus route Prague to Karlsruhe

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Karlsruhe

Here’s an overview of the most popular bus routes to Prague and to Karlsruhe. Simply click on the connection of your choice, and you will find all the details about your bus route!