Bus Messina to Palermo - Compare all Companies

Compare all timetables for the bus from Messina to Palermo

Here is a selection of the cheapest bus trips from the schedule from Messina to Palermo from various bus operators like Sais Autolinee, FlixBus or Itabus for the next days.

today

$13

tomorrow

$16

Sunday

$16

Monday

$16

Tuesday

$16

Wednesday

$16

Thursday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	3h 39m	4:11 AM	Messina	Piazza della Repubblica	7:50 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$13	A Bus from Itabus goes from Piazza della Repubblica, Messina (Italy) at 7/24/2026 4:11:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/24/2026 7:50:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 3h 39m
Sais Autolinee	2h 50m	4:30 AM	Messina	Piazza della Repubblica	7:20 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/24/2026 4:30:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/24/2026 7:20:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 50m
Sais Autolinee	2h 45m	6:30 AM	Messina	Piazza della Repubblica	9:15 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/24/2026 6:30:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/24/2026 9:15:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 45m
FlixBus	4h 35m	6:25 AM	Messina	Piazza della Repubblica	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$23	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/24/2026 6:25:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/24/2026 11:00:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 4h 35m
FlixBus	4h 40m	6:35 AM	Messina	Piazza della Repubblica	11:15 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$23	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/24/2026 6:35:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/24/2026 11:15:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 4h 40m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Sais Autolinee	2h 45m	9:00 AM	Messina	Piazza della Repubblica	11:45 AM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/25/2026 9:00:00 AM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/25/2026 11:45:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 45m
Sais Autolinee	2h 40m	2:15 PM	Messina	Piazza della Repubblica	4:55 PM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/25/2026 2:15:00 PM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/25/2026 4:55:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 40m
Sais Autolinee	2h 40m	6:00 PM	Messina	Piazza della Repubblica	8:40 PM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/25/2026 6:00:00 PM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/25/2026 8:40:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 40m
FlixBus	4h 35m	6:25 AM	Messina	Piazza della Repubblica	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$23	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/25/2026 6:25:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/25/2026 11:00:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 4h 35m
FlixBus	4h 40m	6:35 AM	Messina	Piazza della Repubblica	11:15 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$23	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/25/2026 6:35:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/25/2026 11:15:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 4h 40m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Sais Autolinee	2h 45m	9:00 AM	Messina	Piazza della Repubblica	11:45 AM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/26/2026 9:00:00 AM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/26/2026 11:45:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 45m
Sais Autolinee	2h 40m	12:00 PM	Messina	Piazza della Repubblica	2:40 PM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/26/2026 12:00:00 PM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/26/2026 2:40:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 40m
Sais Autolinee	2h 40m	2:15 PM	Messina	Piazza della Repubblica	4:55 PM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/26/2026 2:15:00 PM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/26/2026 4:55:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 40m
FlixBus	4h 35m	6:25 AM	Messina	Piazza della Repubblica	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$24	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/26/2026 6:25:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/26/2026 11:00:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 4h 35m
FlixBus	4h 40m	6:35 AM	Messina	Piazza della Repubblica	11:15 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$24	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/26/2026 6:35:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/26/2026 11:15:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 4h 40m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Sais Autolinee	2h 50m	4:30 AM	Messina	Piazza della Repubblica	7:20 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/27/2026 4:30:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/27/2026 7:20:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 50m
Sais Autolinee	2h 45m	6:30 AM	Messina	Piazza della Repubblica	9:15 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/27/2026 6:30:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/27/2026 9:15:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 45m
FlixBus	4h 0m	11:15 AM	Messina	Piazza della Repubblica	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$21	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/27/2026 11:15:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/27/2026 3:15:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 4h 0m
FlixBus	5h 20m	2:00 PM	Messina	Piazza della Repubblica	7:20 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$21	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/27/2026 2:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/27/2026 7:20:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 20m
Itabus	3h 39m	4:11 AM	Messina	Piazza della Repubblica	7:50 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$48	A Bus from Itabus goes from Piazza della Repubblica, Messina (Italy) at 7/27/2026 4:11:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/27/2026 7:50:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 3h 39m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Sais Autolinee	2h 45m	4:30 AM	Messina	Piazza della Repubblica	7:15 AM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/28/2026 4:30:00 AM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/28/2026 7:15:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 45m
Sais Autolinee	2h 40m	6:30 AM	Messina	Piazza della Repubblica	9:10 AM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/28/2026 6:30:00 AM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/28/2026 9:10:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 40m
Sais Autolinee	2h 45m	9:00 AM	Messina	Piazza della Repubblica	11:45 AM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/28/2026 9:00:00 AM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/28/2026 11:45:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 45m
FlixBus	4h 35m	6:25 AM	Messina	Piazza della Repubblica	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$22	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/28/2026 6:25:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/28/2026 11:00:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 4h 35m
FlixBus	4h 0m	11:15 AM	Messina	Piazza della Repubblica	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$22	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/28/2026 11:15:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/28/2026 3:15:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 4h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Sais Autolinee	2h 45m	4:30 AM	Messina	Piazza della Repubblica	7:15 AM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/29/2026 4:30:00 AM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/29/2026 7:15:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 45m
Sais Autolinee	2h 40m	6:30 AM	Messina	Piazza della Repubblica	9:10 AM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/29/2026 6:30:00 AM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/29/2026 9:10:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 40m
Sais Autolinee	2h 45m	9:00 AM	Messina	Piazza della Repubblica	11:45 AM	Palermo	Oreto Orsi Bus Stop	Economy	$16	A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 7/29/2026 9:00:00 AM to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 7/29/2026 11:45:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 2h 45m
FlixBus	4h 0m	11:15 AM	Messina	Piazza della Repubblica	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$22	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/29/2026 11:15:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/29/2026 3:15:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 4h 0m
FlixBus	4h 40m	6:35 AM	Messina	Piazza della Repubblica	11:15 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$24	A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/29/2026 6:35:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/29/2026 11:15:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 4h 40m

Best Price Offer: The price for the cheapest bus from Messina to Palermo is $11 on 7/20/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Messina and Palermo

See here how frequent the connections between Messina and Palermo are, during different times and days of the week.

Friday is the busiest day, with more than 79 daily buses from Messina to Palermo. Saturday has instead the fewest connections, with only 18 daily coaches between Messina and Palermo.

The busiest time of the day is the Afternoon, with 134 buses from Messina to Palermo, while Night sees the fewest connections between Messina and Palermo, with 41 offers.

Facts about the bus from Messina to Palermo

Compare all providers like Sais Autolinee, FlixBus and Itabus that travel 53 times every day by bus from Messina to Palermo in one click! Book your bus ticket from Messina to Palermo starting from $11!

Cheapest Bus	$11
Fastest Bus	2h 35m
Earliest Bus	4:11 AM
Latest Bus	6:05 PM
Daily Bus Routes	53 Ø
Distance	119.3 miles
Bus Companies	Sais Autolinee, FlixBus and Itabus

Cheapest bus connections from Messina to Palermo

Every day, 53 buses from 3 bus companies leave Messina for Palermo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

Friday 07/24

$22

Saturday 07/25

$16

Sunday 07/26

$16

Monday 07/27

$16

Tuesday 07/28

$16

Wednesday 07/29

$16

Thursday 07/30

Friday 07/31

$11

Saturday 08/01

$16

Sunday 08/02

$16

Monday 08/03

$13

Tuesday 08/04

$16

Wednesday 08/05

$18

Thursday 08/06

$16

Friday 08/07

$16

Saturday 08/08

$16

Sunday 08/09

$21

Monday 08/10

Tuesday 08/11

$24

Wednesday 08/12

$26

Thursday 08/13

$16

Friday 08/14

Saturday 08/15

The cheapest time to travel from Messina to Palermo

See here on which day and which time of the day you can find the cheapest bus ticket from Messina to Palermo, for the next 30 days.

With a price starting from $11, Friday is the cheapest day for a bus from Messina to Palermo. Sunday instead is the most expensive day with prices starting from $16.

Night is the cheapest day time for bus tickets from Messina to Palermo, with $11. Morning is the most expensive time of the day with prices starting from $16.

How to save money travelling from Messina to Palermo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Messina to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Messina to Palermo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Messina to Palermo are also emptier.

All bus stations and stops in Messina and Palermo

In the map below, you can see where to find all bus stations in Messina and Palermo.

Piazza della Repubblica

Piazza della Repubblica 25

Via Taormina - Policlinico Bus Stop

SS114 Orientale Sicula Bus Stop

Viale Gazzi Bus Stop

SS114 Bus Stop

Oreto Orsi Bus Stop

Via Oreto 389

Piazza Cairoli Bus Station

Piazza Cairoli Piazza Cairoli

Piazza Indipendenza Station

Piazza Indipendenza Palazzo Reale

Via Tommaso Fazello Bus Stop

Via Tommaso Fazello

Via della Libertà

Via della Libertà 163

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Messina to Palermo? Compare all modes of transports from Messina to Palermo.

Service and Comfort on the bus from Messina to Palermo

Want to know which seat classes are available on the buses from Messina to Palermo? Or which bus companies serve the route Messina to Palermo? Below you will find answers to your questions.

FAQs about the Messina to Palermo bus

How much does a Messina Palermo bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $11 and takes 3h 39m to reach Palermo. Compare offers to save money!

How much could I save by comparing buses from Messina to Palermo?

This route is offered by 3 companies with a range of ticket prices between $11 and $53. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Palermo.

On average, how many connections are available from Messina to Palermo each day?

Every day, the Messina to Palermo bus route is served by approximately 53 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Messina to Palermo take?

The fastest bus from Messina to Palermo is offered by Sais Autolinee and takes 2h 35m. Bus tickets for this connection cost $16. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Messina to Palermo?

The earliest bus arriving in Palermo from Messina starts at 4:11 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Messina to Palermo?

The latest bus trip departing from Messina for Palermo starts at 6:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Messina Palermo route?

When traveling by bus from Messina to Palermo, passengers can travel with Sais Autolinee, FlixBus and Itabus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Messina and Palermo?

You can check all the direct connections between Messina and Palermo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Sais Autolinee, FlixBus and Itabus.

What can I take with me on the Messina to Palermo bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Messina Palermo bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Messina Palermo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Messina to Palermo on your planned travel date.

Available seat classes which are offered on the bus route Messina to Palermo

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Messina and to Palermo

Here’s an overview of the most popular bus routes to Messina and to Palermo. Simply click on the connection of your choice, and you will find all the details about your bus route!