Which bus from Madrid to Santander is the cheapest?

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Compare all timetables for the bus from Madrid to Santander

Here is a selection of the cheapest bus trips from the schedule from Madrid to Santander from various bus operators like ALSA or FlixBus for the next days.

today
$45
tomorrow
$41
Monday
$41
Tuesday
$45
Wednesday
$41
Thursday
$41
Friday
$45

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 50m 8:00 AM Madrid Avenida de América Bus Station 1:50 PM Santander Bus Station  Economy $45
ALSA 5h 45m 10:30 AM Madrid Avenida de América Bus Station 4:15 PM Santander Bus Station  Economy $47
ALSA 5h 30m 1:00 PM Madrid Avenida de América Bus Station 6:30 PM Santander Bus Station  Economy $47
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $75
FlixBus 19h 20m 11:30 PM Madrid Sur Bus Station 6:50 PM Santander Bus Station  Economy $101
  • Did you know that if you travel from Madrid to Santander via Palencia, you can save more than $12? You can find the corresponding connections below.
    • ALSA
      8h 0m
      0
      1:15 PM
      Madrid
      Intercambiador de Moncloa
      4:30 PM
      Palencia
      Central bus station
      0
      ALSA
      Economy
      $18
      • Waiting Time 1h 45m
    • ALSA
      3h 0m
      0
      6:15 PM
      Palencia
      Central bus station
      9:15 PM
      Santander
      Bus Station
      0
      ALSA
      Economy
      $15
    Travel time is 2h 30m longer, but you will save $12

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 50m 8:00 AM Madrid Avenida de América Bus Station 1:50 PM Santander Bus Station  Economy $41
ALSA 5h 45m 4:30 PM Madrid Avenida de América Bus Station 10:15 PM Santander Bus Station  Economy $41
ALSA 5h 30m 3:00 PM Madrid Avenida de América Bus Station 8:30 PM Santander Bus Station  Economy $46
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $83
FlixBus 19h 20m 11:30 PM Madrid Sur Bus Station 6:50 PM Santander Bus Station  Economy $94
  • Did you know that if you travel from Madrid to Santander via Palencia, you can save more than $8? You can find the corresponding connections below.
    • ALSA
      8h 0m
      0
      1:15 PM
      Madrid
      Intercambiador de Moncloa
      4:30 PM
      Palencia
      Central bus station
      0
      ALSA
      Economy
      $18
      • Waiting Time 1h 45m
    • ALSA
      3h 0m
      0
      6:15 PM
      Palencia
      Central bus station
      9:15 PM
      Santander
      Bus Station
      0
      ALSA
      Economy
      $15
    Travel time is 2h 30m longer, but you will save $8

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 45m 10:30 AM Madrid Avenida de América Bus Station 4:15 PM Santander Bus Station  Economy $41
ALSA 5h 45m 4:30 PM Madrid Avenida de América Bus Station 10:15 PM Santander Bus Station  Economy $41
ALSA 5h 50m 8:00 AM Madrid Avenida de América Bus Station 1:50 PM Santander Bus Station  Economy $45
FlixBus 19h 20m 11:30 PM Madrid Sur Bus Station 6:50 PM Santander Bus Station  Economy $70
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $73
  • Did you know that if you travel from Madrid to Santander via Palencia, you can save more than $8? You can find the corresponding connections below.
    • ALSA
      8h 0m
      0
      1:15 PM
      Madrid
      Intercambiador de Moncloa
      4:30 PM
      Palencia
      Central bus station
      0
      ALSA
      Economy
      $18
      • Waiting Time 1h 45m
    • ALSA
      3h 0m
      0
      6:15 PM
      Palencia
      Central bus station
      9:15 PM
      Santander
      Bus Station
      0
      ALSA
      Economy
      $15
    Travel time is 2h 15m longer, but you will save $8

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 50m 8:00 AM Madrid Avenida de América Bus Station 1:50 PM Santander Bus Station  Economy $45
ALSA 5h 45m 10:30 AM Madrid Avenida de América Bus Station 4:15 PM Santander Bus Station  Economy $47
ALSA 5h 30m 1:00 PM Madrid Avenida de América Bus Station 6:30 PM Santander Bus Station  Economy $47
FlixBus 19h 20m 11:30 PM Madrid Sur Bus Station 6:50 PM Santander Bus Station  Economy $57
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $70
  • Did you know that if you travel from Madrid to Santander via Palencia, you can save more than $12? You can find the corresponding connections below.
    • ALSA
      8h 0m
      0
      1:15 PM
      Madrid
      Intercambiador de Moncloa
      4:30 PM
      Palencia
      Central bus station
      0
      ALSA
      Economy
      $18
      • Waiting Time 1h 45m
    • ALSA
      3h 0m
      0
      6:15 PM
      Palencia
      Central bus station
      9:15 PM
      Santander
      Bus Station
      0
      ALSA
      Economy
      $15
    Travel time is 2h 30m longer, but you will save $12

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 50m 8:00 AM Madrid Avenida de América Bus Station 1:50 PM Santander Bus Station  Economy $41
ALSA 5h 45m 10:30 AM Madrid Avenida de América Bus Station 4:15 PM Santander Bus Station  Economy $41
ALSA 5h 45m 4:30 PM Madrid Avenida de América Bus Station 10:15 PM Santander Bus Station  Economy $41
FlixBus 19h 20m 11:30 PM Madrid Sur Bus Station 6:50 PM Santander Bus Station  Economy $53
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $63
  • Did you know that if you travel from Madrid to Santander via Palencia, you can save more than $8? You can find the corresponding connections below.
    • ALSA
      8h 0m
      0
      1:15 PM
      Madrid
      Intercambiador de Moncloa
      4:30 PM
      Palencia
      Central bus station
      0
      ALSA
      Economy
      $18
      • Waiting Time 1h 45m
    • ALSA
      3h 0m
      0
      6:15 PM
      Palencia
      Central bus station
      9:15 PM
      Santander
      Bus Station
      0
      ALSA
      Economy
      $15
    Travel time is 2h 15m longer, but you will save $8

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 45m 10:30 AM Madrid Avenida de América Bus Station 4:15 PM Santander Bus Station  Economy $41
ALSA 5h 50m 8:00 AM Madrid Avenida de Aragon 1:50 PM Santander Bus Station  Economy $45
ALSA 5h 45m 4:30 PM Madrid Avenida de Aragon 10:15 PM Santander Bus Station  Economy $45
FlixBus 19h 20m 11:30 PM Madrid Sur Bus Station 6:50 PM Santander Bus Station  Economy $80
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $84
  • Did you know that if you travel from Madrid to Santander via Palencia, you can save more than $8? You can find the corresponding connections below.
    • ALSA
      8h 0m
      0
      1:15 PM
      Madrid
      Intercambiador de Moncloa
      4:30 PM
      Palencia
      Central bus station
      0
      ALSA
      Economy
      $18
      • Waiting Time 1h 45m
    • ALSA
      3h 0m
      0
      6:15 PM
      Palencia
      Central bus station
      9:15 PM
      Santander
      Bus Station
      0
      ALSA
      Economy
      $15
    Travel time is 2h 15m longer, but you will save $8

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 5h 50m 8:00 AM Madrid Avenida de América Bus Station 1:50 PM Santander Bus Station  Economy $45
ALSA 5h 45m 10:30 AM Madrid Avenida de América Bus Station 4:15 PM Santander Bus Station  Economy $47
ALSA 5h 30m 1:00 PM Madrid Avenida de América Bus Station 6:30 PM Santander Bus Station  Economy $47
FlixBus 16h 40m 4:40 PM Madrid Sur Bus Station 9:20 AM Santander Bus Station  Economy $99
FlixBus 19h 20m 11:30 PM Madrid Sur Bus Station 6:50 PM Santander Bus Station  Economy $119
  • Did you know that if you travel from Madrid to Santander via Palencia, you can save more than $12? You can find the corresponding connections below.
    • ALSA
      8h 0m
      0
      1:15 PM
      Madrid
      Intercambiador de Moncloa
      4:30 PM
      Palencia
      Central bus station
      0
      ALSA
      Economy
      $18
      • Waiting Time 1h 45m
    • ALSA
      3h 0m
      0
      6:15 PM
      Palencia
      Central bus station
      9:15 PM
      Santander
      Bus Station
      0
      ALSA
      Economy
      $15
    Travel time is 2h 30m longer, but you will save $12

Best Price Offer: The price for the cheapest bus from Madrid to Santander is $41 on 7/26/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Madrid and Santander

See here how frequent the connections between Madrid and Santander are, during different times and days of the week.
Monday is the busiest day, with more than 26 daily buses from Madrid to Santander. Friday has instead the fewest connections, with only 8 daily coaches between Madrid and Santander.
The busiest time of the day is the Afternoon, with 50 buses from Madrid to Santander, while Night sees the fewest connections between Madrid and Santander, with 16 offers.

Facts about the bus from Madrid to Santander

Compare all providers like ALSA and FlixBus that travel 16 times every day by bus from Madrid to Santander in one click! Book your bus ticket from Madrid to Santander starting from $41!

Cheapest Bus $41
Fastest Bus 5h 30m
Earliest Bus 12:30 AM
Latest Bus 11:30 PM
Daily Bus Routes 16 Ø
Distance 210.6 miles
Bus Companies ALSA and FlixBus

Cheapest bus connections from Madrid to Santander

Every day, 16 buses from 2 bus companies leave Madrid for Santander: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/19
Monday 07/20
Tuesday 07/21
Wednesday 07/22
Thursday 07/23
Friday 07/24
Saturday 07/25
$75
Sunday 07/26
$41
Monday 07/27
$41
Tuesday 07/28
$45
Wednesday 07/29
$45
Thursday 07/30
$41
Friday 07/31
$45
Saturday 08/01
$45
Sunday 08/02
$45
Monday 08/03
$41
Tuesday 08/04
$44
Wednesday 08/05
$81
Thursday 08/06
$41
Friday 08/07
$41
Saturday 08/08
$78
Sunday 08/09
$41
Monday 08/10
$41
Tuesday 08/11
$41
Wednesday 08/12
$83
Thursday 08/13
$45
Friday 08/14
$45
Saturday 08/15

The cheapest time to travel from Madrid to Santander

See here on which day and which time of the day you can find the cheapest bus ticket from Madrid to Santander, for the next 30 days.
With a price starting from $41, Sunday is the cheapest day for a bus from Madrid to Santander. Saturday instead is the most expensive day with prices starting from $45.
Morning is the cheapest day time for bus tickets from Madrid to Santander, with $41. Evening is the most expensive time of the day with prices starting from $45.

How to save money travelling from Madrid to Santander

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madrid to Santander in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Santander, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madrid to Santander are also emptier.

All bus stations and stops in Madrid and Santander

In the map below, you can see where to find all bus stations in Madrid and Santander.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Madrid to Santander? Compare all modes of transports from Madrid to Santander.

Service and Comfort on the bus from Madrid to Santander

Want to know which seat classes are available on the buses from Madrid to Santander? Or which bus companies serve the route Madrid to Santander? Below you will find answers to your questions.

FAQs about the Madrid to Santander bus

How much does a Madrid Santander bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $41 and takes 5h 50m to reach Santander. Compare offers to save money!

How much could I save by comparing buses from Madrid to Santander?

This route is offered by 2 companies with a range of ticket prices between $41 and $129. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santander.

On average, how many connections are available from Madrid to Santander each day?

Every day, the Madrid to Santander bus route is served by approximately 16 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Madrid to Santander take?

The fastest bus from Madrid to Santander is offered by ALSA and takes 5h 30m. Bus tickets for this connection cost $47. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Madrid to Santander?

The earliest bus arriving in Santander from Madrid starts at 12:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Madrid to Santander?

The latest bus trip departing from Madrid for Santander starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Madrid Santander route?

When traveling by bus from Madrid to Santander, passengers can travel with ALSA and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Madrid and Santander?

You can check all the direct connections between Madrid and Santander by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ALSA and FlixBus.

What can I take with me on the Madrid to Santander bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Madrid Santander bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Madrid Santander bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madrid to Santander on your planned travel date.

Available seat classes which are offered on the bus route Madrid to Santander

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madrid and to Santander

Here’s an overview of the most popular bus routes to Madrid and to Santander. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Madrid from Miramar Bus to Madrid from Miramar
Bus to Madrid from San Pablo de los Montes Bus to Madrid from San Pablo de los Montes
Bus San Rafael - Madrid Bus San Rafael - Madrid
Buses to Madrid from Mönchengladbach Buses to Madrid from Mönchengladbach
Bus Laredo - Santander Bus Laredo - Santander
From Llanes to Santander bus From Llanes to Santander bus
Bus Castro Urdiales to Santander Bus Castro Urdiales to Santander
Buses from Segovia to Santander Buses from Segovia to Santander
Popular Airport Shuttles to Madrid and to Santander
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