Bus Lyon to Milan - Compare all Companies

Compare all timetables for the bus from Lyon to Milan

Here is a selection of the cheapest bus trips from the schedule from Lyon to Milan from various bus operators like Itabus, FlixBus or BlaBlaCar Bus for the next days.

today

$38

tomorrow

$17

Sunday

$23

Monday

$29

Tuesday

$17

Wednesday

$18

Thursday

$23

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 25m	11:50 PM	Lyon	Perrache Bus Stop	6:15 AM	Milan	Lampugnano Bus Station	Premium Economy	$38	A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 7/24/2026 11:50:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 6:15:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 6h 25m
FlixBus	6h 5m	6:00 PM	Lyon		12:05 AM	Milan	Lampugnano Bus Station	Economy	$42	A Bus from FlixBus goes from , Lyon (France) at 7/24/2026 6:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 12:05:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 6h 5m
FlixBus	6h 25m	11:00 PM	Lyon		5:25 AM	Milan	Lampugnano Bus Station	Economy	$50	A Bus from FlixBus goes from , Lyon (France) at 7/24/2026 11:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 5:25:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 6h 25m
BlaBlaCar Bus	6h 11m	11:59 PM	Lyon	Perrache Train Station	6:10 AM	Milan	Lampugnano Bus Station	Economy	$51	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/24/2026 11:59:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 6:10:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 6h 11m
BlaBlaCar Bus	6h 25m	11:35 PM	Lyon	Perrache Train Station	6:00 AM	Milan	Lampugnano Bus Station	Economy	$80	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/24/2026 11:35:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 6:00:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 6h 25m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 50m	3:30 PM	Lyon	Perrache Bus Stop	10:20 PM	Milan	Lampugnano Bus Station	Premium Economy	$17	A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 7/25/2026 3:30:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 10:20:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 6h 50m
Itabus	6h 25m	11:50 PM	Lyon	Perrache Bus Stop	6:15 AM	Milan	Lampugnano Bus Station	Premium Economy	$25	A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 7/25/2026 11:50:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 6:15:00 AM. 50 Premium Economy ticket for $25 per person are available. Travel duration is 6h 25m
BlaBlaCar Bus	6h 25m	11:35 PM	Lyon	Perrache Train Station	6:00 AM	Milan	Lampugnano Bus Station	Economy	$28	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/25/2026 11:35:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 6:00:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 25m
BlaBlaCar Bus	6h 11m	11:59 PM	Lyon	Perrache Train Station	6:10 AM	Milan	Lampugnano Bus Station	Economy	$28	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/25/2026 11:59:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 6:10:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 11m
FlixBus	6h 30m	4:00 PM	Lyon		10:30 PM	Milan	Lampugnano Bus Station	Economy	$36	A Bus from FlixBus goes from , Lyon (France) at 7/25/2026 4:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 10:30:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 6h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 50m	3:30 PM	Lyon	Perrache Bus Stop	10:20 PM	Milan	Lampugnano Bus Station	Premium Economy	$23	A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 7/26/2026 3:30:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 10:20:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 6h 50m
Itabus	6h 40m	5:40 AM	Lyon	Perrache Bus Stop	12:20 PM	Milan	Lampugnano Bus Station	Economy	$26	A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 7/26/2026 5:40:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 12:20:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 6h 40m
BlaBlaCar Bus	7h 45m	11:00 AM	Lyon	Perrache Train Station	6:45 PM	Milan	Lampugnano Bus Station	Economy	$34	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/26/2026 11:00:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 6:45:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 45m
FlixBus	7h 0m	2:55 PM	Lyon		9:55 PM	Milan	Lampugnano Bus Station	Economy	$39	A Bus from FlixBus goes from , Lyon (France) at 7/26/2026 2:55:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 9:55:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 7h 0m
FlixBus	6h 30m	4:00 PM	Lyon		10:30 PM	Milan	Lampugnano Bus Station	Economy	$40	A Bus from FlixBus goes from , Lyon (France) at 7/26/2026 4:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 10:30:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 6h 30m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 35m	9:15 AM	Lyon		3:50 PM	Milan	Lampugnano Bus Station	Premium Economy	$29	A Bus from Itabus goes from , Lyon (France) at 7/27/2026 9:15:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 3:50:00 PM. 50 Premium Economy ticket for $29 per person are available. Travel duration is 6h 35m
BlaBlaCar Bus	7h 35m	9:45 AM	Lyon	Perrache Train Station	5:20 PM	Milan	Lampugnano Bus Station	Economy	$34	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/27/2026 9:45:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 5:20:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 35m
BlaBlaCar Bus	7h 45m	11:00 AM	Lyon	Perrache Train Station	6:45 PM	Milan	Lampugnano Bus Station	Economy	$34	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/27/2026 11:00:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 6:45:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 45m
Itabus	6h 50m	3:30 PM	Lyon	Perrache Bus Stop	10:20 PM	Milan	Lampugnano Bus Station	Premium Economy	$34	A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 7/27/2026 3:30:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 10:20:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 6h 50m
FlixBus	7h 0m	2:55 PM	Lyon		9:55 PM	Milan	Lampugnano Bus Station	Economy	$36	A Bus from FlixBus goes from , Lyon (France) at 7/27/2026 2:55:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 9:55:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 7h 0m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 50m	3:30 PM	Lyon	Perrache Bus Stop	10:20 PM	Milan	Lampugnano Bus Station	Premium Economy	$17	A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 7/28/2026 3:30:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 10:20:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 6h 50m
Itabus	6h 25m	11:50 PM	Lyon		6:15 AM	Milan	Lampugnano Bus Station	Economy	$32	A Bus from Itabus goes from , Lyon (France) at 7/28/2026 11:50:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 6:15:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 25m
FlixBus	7h 0m	2:55 PM	Lyon		9:55 PM	Milan	Lampugnano Bus Station	Economy	$34	A Bus from FlixBus goes from , Lyon (France) at 7/28/2026 2:55:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 9:55:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 0m
FlixBus	7h 5m	6:15 AM	Lyon		1:20 PM	Milan	Lampugnano Bus Station	Economy	$36	A Bus from FlixBus goes from , Lyon (France) at 7/28/2026 6:15:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 1:20:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 7h 5m
BlaBlaCar Bus	7h 45m	11:00 AM	Lyon	Perrache Train Station	6:45 PM	Milan	Lampugnano Bus Station	Economy	$40	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/28/2026 11:00:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 6:45:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 45m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Union Ivkoni	6h 45m	6:45 AM	Lyon		1:30 PM	Milan	Lampugnano Bus Station	Economy	$18	A Bus from Union Ivkoni goes from , Lyon (France) at 7/29/2026 6:45:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 1:30:00 PM. 50 Economy ticket for $18 per person are available. Travel duration is 6h 45m
Itabus	6h 50m	3:30 PM	Lyon	Perrache Bus Stop	10:20 PM	Milan	Lampugnano Bus Station	Economy	$19	A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 7/29/2026 3:30:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 10:20:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 6h 50m
Itabus	6h 40m	5:40 AM	Lyon		12:20 PM	Milan	Lampugnano Bus Station	Premium Economy	$23	A Bus from Itabus goes from , Lyon (France) at 7/29/2026 5:40:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 12:20:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 6h 40m
BlaBlaCar Bus	6h 15m	1:45 AM	Lyon	Perrache Train Station	8:00 AM	Milan	Lampugnano Bus Station	Economy	$34	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/29/2026 1:45:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 8:00:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 6h 15m
BlaBlaCar Bus	7h 5m	7:00 AM	Lyon	Perrache Train Station	2:05 PM	Milan	Lampugnano Bus Station	Economy	$34	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/29/2026 7:00:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 2:05:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 5m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 50m	3:30 PM	Lyon	Perrache Bus Stop	10:20 PM	Milan	Lampugnano Bus Station	Premium Economy	$23	A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 7/30/2026 3:30:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 10:20:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 6h 50m
Itabus	6h 35m	9:15 AM	Lyon	Perrache Bus Stop	3:50 PM	Milan	Lampugnano Bus Station	Premium Economy	$27	A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 7/30/2026 9:15:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 3:50:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 6h 35m
FlixBus	7h 0m	2:55 PM	Lyon		9:55 PM	Milan	Lampugnano Bus Station	Economy	$34	A Bus from FlixBus goes from , Lyon (France) at 7/30/2026 2:55:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 9:55:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 0m
BlaBlaCar Bus	7h 5m	7:00 AM	Lyon	Perrache Train Station	2:05 PM	Milan	Lampugnano Bus Station	Economy	$34	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/30/2026 7:00:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 2:05:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 5m
BlaBlaCar Bus	7h 35m	9:45 AM	Lyon	Perrache Train Station	5:20 PM	Milan	Lampugnano Bus Station	Economy	$34	A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/30/2026 9:45:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 5:20:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 35m

Best Price Offer: The price for the cheapest bus from Lyon to Milan is $17 on 7/25/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Lyon and Milan

See here how frequent the connections between Lyon and Milan are, during different times and days of the week.

Saturday is the busiest day, with more than 36 daily buses from Lyon to Milan. Friday has instead the fewest connections, with only 8 daily coaches between Lyon and Milan.

The busiest time of the day is the Evening, with 56 buses from Lyon to Milan, while Night sees the fewest connections between Lyon and Milan, with 40 offers.

Facts about the bus from Lyon to Milan

Compare all providers like Itabus, FlixBus and BlaBlaCar Bus that travel 28 times every day by bus from Lyon to Milan in one click! Book your bus ticket from Lyon to Milan starting from $17!

Cheapest Bus	$17
Fastest Bus	6h 5m
Earliest Bus	6:00 PM
Latest Bus	11:59 PM
Daily Bus Routes	28 Ø
Distance	211.3 miles
Bus Companies	Itabus, FlixBus, BlaBlaCar Bus and Union Ivkoni

Cheapest bus connections from Lyon to Milan

Every day, 28 buses from 4 bus companies leave Lyon for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

Friday 07/24

$38

Saturday 07/25

$39

Sunday 07/26

$20

Monday 07/27

$28

Tuesday 07/28

$17

Wednesday 07/29

$35

Thursday 07/30

$23

Friday 07/31

$39

Saturday 08/01

$28

Sunday 08/02

$25

Monday 08/03

$20

Tuesday 08/04

$20

Wednesday 08/05

$17

Thursday 08/06

$30

Friday 08/07

$28

Saturday 08/08

$34

Sunday 08/09

$28

Monday 08/10

$19

Tuesday 08/11

$17

Wednesday 08/12

$34

Thursday 08/13

$23

Friday 08/14

$23

Saturday 08/15

The cheapest time to travel from Lyon to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Lyon to Milan, for the next 30 days.

With a price starting from $17, Tuesday is the cheapest day for a bus from Lyon to Milan. Friday instead is the most expensive day with prices starting from $23.

Afternoon is the cheapest day time for bus tickets from Lyon to Milan, with $17. Evening is the most expensive time of the day with prices starting from $25.

How to save money travelling from Lyon to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lyon to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lyon to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lyon to Milan are also emptier.

Latest reviews for bus companies on the route Lyon - Milan

crepieux ruben, 3/18/2025

chauffeur parfaitement capable de conduire, trajets trés agréable malgré ma séparation avec mon camarade en début de trajets. trés bonne conduite.

All bus stations and stops in Lyon and Milan

In the map below, you can see where to find all bus stations in Lyon and Milan.

Perrache Bus Stop

Cours de Verdun 14

Saint Paul Train Station

Pont Kitchener R.G. Bus Stop

Cours de Verdun

Maison Carrée Bus Stop

Les Charrières 69570

Girondins - Yves Farge Bus Stop

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Central Bus Station

Duomo Bus Stop

Piazza del Duomo

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Lyon to Milan? Compare all modes of transports from Lyon to Milan.

Service and Comfort on the bus from Lyon to Milan

Want to know which seat classes are available on the buses from Lyon to Milan? Or which bus companies serve the route Lyon to Milan? Below you will find answers to your questions.

FAQs about the Lyon to Milan bus

How much does a Lyon Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $17 and takes 6h 50m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Lyon to Milan?

This route is offered by 4 companies with a range of ticket prices between $17 and $110. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Lyon to Milan each day?

Every day, the Lyon to Milan bus route is served by approximately 28 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lyon to Milan take?

The fastest bus from Lyon to Milan is offered by FlixBus and takes 6h 5m. Bus tickets for this connection cost $42. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lyon to Milan?

The earliest bus arriving in Milan from Lyon starts at 6:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lyon to Milan?

The latest bus trip departing from Lyon for Milan starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lyon Milan route?

When traveling by bus from Lyon to Milan, passengers can travel with Itabus, FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lyon and Milan?

You can check all the direct connections between Lyon and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus, FlixBus and BlaBlaCar Bus.

What can I take with me on the Lyon to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lyon Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lyon Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lyon to Milan on your planned travel date.

Available seat classes which are offered on the bus route Lyon to Milan

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Lyon and to Milan

Here’s an overview of the most popular bus routes to Lyon and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!