Bus Lake City, FL to Houston: Compare prices and save money

Compare all timetables for the bus from Lake City, FL to Houston

Here is a selection of the cheapest bus trips from the schedule from Lake City, FL to Houston from various bus operators like Greyhound US for the next days.

today

tomorrow

$100

Wednesday

$105

Thursday

$102

Friday

$115

Saturday

Sunday

$115

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 35m	9:35 AM	Lake City, FL	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$100	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/28/2026 9:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 7/29/2026 7:10:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 22h 35m
Greyhound US	20h 30m	9:35 AM	Lake City, FL	Bus Stop	5:05 AM	Houston	Downtown Houston	Economy	$101	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/28/2026 9:35:00 AM to Downtown Houston, Houston (USA) arriving at 7/29/2026 5:05:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 20h 30m
Greyhound US	31h 0m	7:30 PM	Lake City, FL	Bus Stop	1:30 AM	Houston	Harrisburg Blvd Station	Economy	$102	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/28/2026 7:30:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 7/30/2026 1:30:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 31h 0m
Greyhound US	28h 40m	5:20 PM	Lake City, FL	Bus Stop	9:00 PM	Houston	Downtown Houston	Economy	$102	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/28/2026 5:20:00 PM to Downtown Houston, Houston (USA) arriving at 7/29/2026 9:00:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 28h 40m
Greyhound US	19h 0m	5:20 PM	Lake City, FL	Bus Stop	11:20 AM	Houston	Harrisburg Blvd Station	Economy	$103	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/28/2026 5:20:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 7/29/2026 11:20:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 19h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 35m	9:35 AM	Lake City, FL	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$105	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/29/2026 9:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 7/30/2026 7:10:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 22h 35m
Greyhound US	19h 0m	5:20 PM	Lake City, FL	Bus Stop	11:20 AM	Houston	Harrisburg Blvd Station	Economy	$105	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/29/2026 5:20:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 7/30/2026 11:20:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 19h 0m
Greyhound US	21h 55m	5:20 PM	Lake City, FL	Bus Stop	2:15 PM	Houston	Downtown Houston	Economy	$105	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/29/2026 5:20:00 PM to Downtown Houston, Houston (USA) arriving at 7/30/2026 2:15:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 21h 55m
Greyhound US	34h 35m	7:30 PM	Lake City, FL	Bus Stop	5:05 AM	Houston	Downtown Houston	Economy	$105	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/29/2026 7:30:00 PM to Downtown Houston, Houston (USA) arriving at 7/31/2026 5:05:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 34h 35m
Greyhound US	31h 0m	7:30 PM	Lake City, FL	Bus Stop	1:30 AM	Houston	Harrisburg Blvd Station	Economy	$107	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/29/2026 7:30:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 7/31/2026 1:30:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 31h 0m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	20h 30m	9:35 AM	Lake City, FL	Bus Stop	5:05 AM	Houston	Downtown Houston	Economy	$102	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/30/2026 9:35:00 AM to Downtown Houston, Houston (USA) arriving at 7/31/2026 5:05:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 20h 30m
Greyhound US	22h 35m	9:35 AM	Lake City, FL	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$103	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/30/2026 9:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 7/31/2026 7:10:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 22h 35m
Greyhound US	21h 55m	5:20 PM	Lake City, FL	Bus Stop	2:15 PM	Houston	Downtown Houston	Economy	$105	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/30/2026 5:20:00 PM to Downtown Houston, Houston (USA) arriving at 7/31/2026 2:15:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 21h 55m
Greyhound US	19h 0m	5:20 PM	Lake City, FL	Bus Stop	11:20 AM	Houston	Harrisburg Blvd Station	Economy	$114	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/30/2026 5:20:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 7/31/2026 11:20:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 19h 0m
Greyhound US	31h 0m	7:30 PM	Lake City, FL	Bus Stop	1:30 AM	Houston	Harrisburg Blvd Station	Economy	$120	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/30/2026 7:30:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 8/1/2026 1:30:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 31h 0m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 55m	5:20 PM	Lake City, FL	Bus Stop	2:15 PM	Houston	Downtown Houston	Economy	$115	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/31/2026 5:20:00 PM to Downtown Houston, Houston (USA) arriving at 8/1/2026 2:15:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 21h 55m
Greyhound US	22h 35m	9:35 AM	Lake City, FL	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$116	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/31/2026 9:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 8/1/2026 7:10:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 22h 35m
Greyhound US	20h 30m	9:35 AM	Lake City, FL	Bus Stop	5:05 AM	Houston	Downtown Houston	Economy	$116	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/31/2026 9:35:00 AM to Downtown Houston, Houston (USA) arriving at 8/1/2026 5:05:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 20h 30m
Greyhound US	19h 0m	5:20 PM	Lake City, FL	Bus Stop	11:20 AM	Houston	Harrisburg Blvd Station	Economy	$117	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/31/2026 5:20:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 8/1/2026 11:20:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 19h 0m
Greyhound US	31h 0m	7:30 PM	Lake City, FL	Bus Stop	1:30 AM	Houston	Harrisburg Blvd Station	Economy	$118	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/31/2026 7:30:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 8/2/2026 1:30:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 31h 0m

Did you know that if you travel from Lake City, FL to Houston via Tallahassee, FL, you can save more than $16? You can find the corresponding connections below.
- Greyhound US
  
  19h 0m
  
  0
  
  5:20 PM
  
  Lake City, FL
  Bus Stop
  
  7:25 PM
  
  Tallahassee, FL
  Greyhound Bus Station
  
  0
  
  Economy
  
  $25
  
  A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 7/31/2026 5:20:00 PM to Greyhound Bus Station, Tallahassee, FL (USA) arriving at 7/31/2026 7:25:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 2h 5m
- Greyhound US
  
  15h 55m
  
  0
  
  8:25 PM
  
  Tallahassee, FL
  Greyhound Bus Station
  
  11:20 AM
  
  Houston
  Harrisburg Blvd Station
  
  0
  
  Economy
  
  $74
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 7/31/2026 8:25:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 8/1/2026 11:20:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 15h 55m
Travel time is 1h 0m longer, but you will save $16

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 55m	5:20 PM	Lake City, FL	Bus Stop	2:15 PM	Houston	Downtown Houston	Economy	$115	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 8/2/2026 5:20:00 PM to Downtown Houston, Houston (USA) arriving at 8/3/2026 2:15:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 21h 55m
Greyhound US	22h 35m	9:35 AM	Lake City, FL	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$116	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 8/2/2026 9:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 8/3/2026 7:10:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 22h 35m
Greyhound US	20h 30m	9:35 AM	Lake City, FL	Bus Stop	5:05 AM	Houston	Downtown Houston	Economy	$116	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 8/2/2026 9:35:00 AM to Downtown Houston, Houston (USA) arriving at 8/3/2026 5:05:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 20h 30m
Greyhound US	19h 0m	5:20 PM	Lake City, FL	Bus Stop	11:20 AM	Houston	Harrisburg Blvd Station	Economy	$117	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 8/2/2026 5:20:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 8/3/2026 11:20:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 19h 0m
Greyhound US	34h 35m	7:30 PM	Lake City, FL	Bus Stop	5:05 AM	Houston	Downtown Houston	Economy	$117	A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 8/2/2026 7:30:00 PM to Downtown Houston, Houston (USA) arriving at 8/4/2026 5:05:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 34h 35m

Did you know that if you travel from Lake City, FL to Houston via Tallahassee, FL, you can save more than $19? You can find the corresponding connections below.
- Greyhound US
  
  19h 0m
  
  0
  
  5:20 PM
  
  Lake City, FL
  Bus Stop
  
  7:25 PM
  
  Tallahassee, FL
  Greyhound Bus Station
  
  0
  
  Economy
  
  $25
  
  A Bus from Greyhound US goes from Bus Stop, Lake City, FL (USA) at 8/2/2026 5:20:00 PM to Greyhound Bus Station, Tallahassee, FL (USA) arriving at 8/2/2026 7:25:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 2h 5m
- Greyhound US
  
  15h 55m
  
  0
  
  8:25 PM
  
  Tallahassee, FL
  Greyhound Bus Station
  
  11:20 AM
  
  Houston
  Harrisburg Blvd Station
  
  0
  
  Economy
  
  $71
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 8/2/2026 8:25:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 8/3/2026 11:20:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 15h 55m
Travel time is 1h 0m longer, but you will save $19

Frequency of bus connections between Lake City, FL and Houston

See here how frequent the connections between Lake City, FL and Houston are, during different times and days of the week.

Sunday is the busiest day, with more than 6 daily buses from Lake City, FL to Houston. Tuesday has instead the fewest connections, with only 5 daily coaches between Lake City, FL and Houston.

The busiest time of the day is the Afternoon, with 10 buses from Lake City, FL to Houston, while Morning sees the fewest connections between Lake City, FL and Houston, with 9 offers.

Test cheapest views

The cheapest bus for the 7/28/2026 costs just $100, from Greyhound US

Facts about the bus from Lake City, FL to Houston

Compare all providers like Greyhound US that travel 5 times every day by bus from Lake City, FL to Houston in one click! Book your bus ticket from Lake City, FL to Houston starting from $100!

Cheapest Bus	$100
Fastest Bus	18h 0m
Earliest Bus	9:35 AM
Latest Bus	7:30 PM
Daily Bus Routes	5 Ø
Distance	762.5 miles
Bus Companies	Greyhound US

Cheapest bus connections from Lake City, FL to Houston

Every day, 5 buses from 1 bus companies leave Lake City, FL for Houston: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

Monday 07/27

Tuesday 07/28

$100

Wednesday 07/29

$105

Thursday 07/30

$102

Friday 07/31

$115

Saturday 08/01

Sunday 08/02

$115

Monday 08/03

Tuesday 08/04

Wednesday 08/05

Thursday 08/06

$108

Friday 08/07

Saturday 08/08

Sunday 08/09

$109

Monday 08/10

Tuesday 08/11

$111

Wednesday 08/12

Thursday 08/13

Friday 08/14

Saturday 08/15

Sunday 08/16

Monday 08/17

Tuesday 08/18

Wednesday 08/19

Thursday 08/20

Friday 08/21

Saturday 08/22

The cheapest time to travel from Lake City, FL to Houston

See here on which day and which time of the day you can find the cheapest bus ticket from Lake City, FL to Houston, for the next 30 days.

With a price starting from $100, Tuesday is the cheapest day for a bus from Lake City, FL to Houston. Friday instead is the most expensive day with prices starting from $115.

Morning is the cheapest day time for bus tickets from Lake City, FL to Houston, with $100. Evening is the most expensive time of the day with prices starting from $102.

How to save money travelling from Lake City, FL to Houston

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lake City, FL to Houston in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lake City, FL to Houston, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lake City, FL to Houston are also emptier.

All bus stations and stops in Lake City, FL and Houston

In the map below, you can see where to find all bus stations in Lake City, FL and Houston.

Bus Stop

S Marion Ave 251

Lake City Bus Stop

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Chase Bank

Milam Street 212

Uptown/Upper Kirby

Southwest Fwy 2525

Service and Comfort on the bus from Lake City, FL to Houston

Want to know which seat classes are available on the buses from Lake City, FL to Houston? Or which bus companies serve the route Lake City, FL to Houston? Below you will find answers to your questions.

FAQs about the Lake City, FL to Houston bus

How much does a Lake City, FL Houston bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $100 and takes 21h 35m to reach Houston. Compare offers to save money!

How much could I save by comparing buses from Lake City, FL to Houston?

This route is offered by 1 companies with a range of ticket prices between $100 and $120. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Houston.

On average, how many connections are available from Lake City, FL to Houston each day?

Every day, the Lake City, FL to Houston bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lake City, FL to Houston take?

The fastest bus from Lake City, FL to Houston is offered by Greyhound US and takes 18h 0m. Bus tickets for this connection cost $103. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lake City, FL to Houston?

The earliest bus arriving in Houston from Lake City, FL starts at 9:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lake City, FL to Houston?

The latest bus trip departing from Lake City, FL for Houston starts at 7:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lake City, FL Houston route?

When traveling by bus from Lake City, FL to Houston, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lake City, FL and Houston?

You can check all the direct connections between Lake City, FL and Houston by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Lake City, FL to Houston bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lake City, FL Houston bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lake City, FL Houston bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lake City, FL to Houston on your planned travel date.

Available seat classes which are offered on the bus route Lake City, FL to Houston

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lake City, FL and to Houston

Here’s an overview of the most popular bus routes to Lake City, FL and to Houston. Simply click on the connection of your choice, and you will find all the details about your bus route!