Compare all timetables for the bus from Knoxville, TN to Chicago
Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to Chicago from various bus operators like Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 20h 0m | 10:00 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | 5:00 PM | Chicago | 95th Red Line Station | Economy | $91 |
A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 9/8/2026 10:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 9/9/2026 5:00:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 20h 0m
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| Greyhound US | 16h 55m | 5:55 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | 9:50 AM | Chicago | 95th Red Line Station | Economy | $112 |
A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 9/8/2026 5:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 9/9/2026 9:50:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 16h 55m
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| Greyhound US | 20h 35m | 10:00 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | 5:35 PM | Chicago | Downtown Bus Station | Economy | $142 |
A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 9/8/2026 10:00:00 PM to Downtown Bus Station, Chicago (USA) arriving at 9/9/2026 5:35:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 20h 35m
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| Greyhound US | 20h 15m | 8:00 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | 3:15 PM | Chicago | Downtown Bus Station | Economy | $143 |
A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 9/8/2026 8:00:00 PM to Downtown Bus Station, Chicago (USA) arriving at 9/9/2026 3:15:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 20h 15m
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| Greyhound US | 15h 5m | 5:55 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | 8:00 AM | Chicago | Canal & Van Buren | Economy | $164 |
A Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 9/8/2026 5:55:00 PM to Canal & Van Buren, Chicago (USA) arriving at 9/9/2026 8:00:00 AM. 50 Economy ticket for $164 per person are available. Travel duration is 15h 5m
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Test cheapest views
The cheapest bus for the 9/8/2026 costs just $91, from Greyhound US
Facts about the bus from Knoxville, TN to Chicago
Compare all providers like Greyhound US that travel 6 times every day by bus from Knoxville, TN to Chicago in one click! Book your bus ticket from Knoxville, TN to Chicago starting from $91!
| Cheapest Bus | $91 |
| Fastest Bus | 14h 5m |
| Earliest Bus | 5:55 PM |
| Latest Bus | 10:00 PM |
| Daily Bus Routes | 6 Ø |
| Distance | 455.0 miles |
| Bus Companies | Greyhound US |
Cheapest bus connections from Knoxville, TN to Chicago
Every day, 6 buses from 1 bus companies leave Knoxville, TN for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/08/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
09/06
Monday
09/07
Tuesday
09/08
$91
Wednesday
09/09
Thursday
09/10
Friday
09/11
Saturday
09/12
Sunday
09/13
Monday
09/14
Tuesday
09/15
Wednesday
09/16
Thursday
09/17
Friday
09/18
Saturday
09/19
Sunday
09/20
Monday
09/21
$104
Tuesday
09/22
Wednesday
09/23
Thursday
09/24
Friday
09/25
Saturday
09/26
Sunday
09/27
Monday
09/28
Tuesday
09/29
Wednesday
09/30
Thursday
10/01
Friday
10/02
Saturday
10/03
How to save money travelling from Knoxville, TN to Chicago
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Knoxville, TN to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Chicago, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Chicago are also emptier.All bus stations and stops in Knoxville, TN and Chicago
In the map below, you can see where to find all bus stations in Knoxville, TN and Chicago.
Service and Comfort on the bus from Knoxville, TN to Chicago
Want to know which seat classes are available on the buses from Knoxville, TN to Chicago? Or which bus companies serve the route Knoxville, TN to Chicago? Below you will find answers to your questions.
FAQs about the Knoxville, TN to Chicago bus
How much does a Knoxville, TN Chicago bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $91 and takes 19h 0m to reach Chicago. Compare offers to save money!
How much could I save by comparing buses from Knoxville, TN to Chicago?
This route is offered by 1 companies with a range of ticket prices between $91 and $164. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.
On average, how many connections are available from Knoxville, TN to Chicago each day?
Every day, the Knoxville, TN to Chicago bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Knoxville, TN to Chicago take?
The fastest bus from Knoxville, TN to Chicago is offered by Greyhound US and takes 14h 5m. Bus tickets for this connection cost $164. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Knoxville, TN to Chicago?
The earliest bus arriving in Chicago from Knoxville, TN starts at 5:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Knoxville, TN to Chicago?
The latest bus trip departing from Knoxville, TN for Chicago starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Knoxville, TN Chicago route?
When traveling by bus from Knoxville, TN to Chicago, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Knoxville, TN and Chicago?
You can check all the direct connections between Knoxville, TN and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.
What can I take with me on the Knoxville, TN to Chicago bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Knoxville, TN Chicago bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to Chicago on your planned travel date.
Available seat classes which are offered on the bus route Knoxville, TN to Chicago
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Knoxville, TN and to Chicago
Here’s an overview of the most popular bus routes to Knoxville, TN and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Knoxville, TN
- Bus from Atlanta, GA to Knoxville, TN
- Buses Chattanooga, TN - Knoxville, TN
- Buses El Cajon, CA to Knoxville, TN
- From Houston to Knoxville, TN bus
- Los Angeles to Knoxville, TN bus
- Memphis to Knoxville, TN bus
- Buses to Knoxville, TN from Miami
- Bus from Mobile, AL to Knoxville, TN
- Bus New York to Knoxville, TN
- Oakland to Knoxville, TN bus
- Phoenix, AZ to Knoxville, TN bus
- Buses to Knoxville, TN from Poza Rica
- Bus Queens Village, NY to Knoxville, TN
- Buses to Knoxville, TN from Raleigh, NC
- Bus Reynosa - Knoxville, TN
- Bus Roanoke, VA to Knoxville, TN
- Bus Shreveport, LA to Knoxville, TN
- Buses to Knoxville, TN from Spring Hill, FL
- Bus from Tampa to Knoxville, TN
- Buses Toronto, ON to Knoxville, TN
- Bus Routes to Chicago
- Bus to Chicago from College Station, TX
- Buses from Denver to Chicago
- Bus Detroit to Chicago
- Buses El Paso, TX - Chicago
- Houston to Chicago bus
- Bus from León de los Aldama to Chicago
- Bus from Manchester, NH to Chicago
- Montreal to Chicago bus
- Buses Nashville - Chicago
- Bus Oklahoma City, OK - Chicago
- Buses from Philadelphia to Chicago
- Bus to Chicago from Phoenix, AZ
- Bus Pueblo, CO to Chicago
- Bus Queens Village, NY - Chicago
- Bus to Chicago from San Antonio, TX
- Bus San Diego - Chicago
- Buses to Chicago from Santiago de Queretaro
- Bus Tijuana, BC - Chicago
- Buses Washington, DC - Chicago
- Bus Windsor, ON to Chicago
Popular Airport Shuttles to Knoxville, TN and to Chicago
