Bus Karlsruhe to Milan - Compare all Companies

Compare all timetables for the bus from Karlsruhe to Milan

Here is a selection of the cheapest bus trips from the schedule from Karlsruhe to Milan from various bus operators like FlixBus or BlaBlaCar Bus for the next days.

today

$58

tomorrow

$46

Saturday

$46

Sunday

Monday

$41

Tuesday

$38

Wednesday

$43

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 10m	11:00 PM	Karlsruhe	Central Station	7:10 AM	Milan	Lampugnano Bus Station	Economy	$58	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/23/2026 11:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 7:10:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 8h 10m
FlixBus	8h 55m	8:10 PM	Karlsruhe	Central Station	5:05 AM	Milan	Lampugnano Bus Station	Economy	$63	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/23/2026 8:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 5:05:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 8h 55m
FlixBus	8h 25m	11:40 PM	Karlsruhe	Central Station	8:05 AM	Milan	Lampugnano Bus Station	Economy	$68	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/23/2026 11:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 8:05:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 25m
BlaBlaCar Bus	17h 0m	9:05 PM	Karlsruhe	Central Station	2:05 PM	Milan	Lampugnano Bus Station	Economy	$108	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/23/2026 9:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 2:05:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 17h 0m

Did you know that if you travel from Karlsruhe to Milan via Zurich, you can save more than $14? You can find the corresponding connections below.
- FlixBus
  
  11h 25m
  
  0
  
  11:05 AM
  
  Karlsruhe
  Central Station
  
  3:10 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $25
  
  A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/25/2026 11:05:00 AM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 7/25/2026 3:10:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 4h 5m
- Itabus
  
  5h 10m
  
  0
  
  5:20 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  10:30 PM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Economy
  
  $19
  
  A Bus from Itabus goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 7/25/2026 5:20:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 10:30:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 5h 10m
Travel time is 3h 15m longer, but you will save $14

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 20m	9:30 AM	Karlsruhe	Central Station	4:50 PM	Milan	Lampugnano Bus Station	Economy	$46	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/24/2026 9:30:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 4:50:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 7h 20m
FlixBus	8h 10m	11:05 AM	Karlsruhe	Central Station	7:15 PM	Milan	Lampugnano Bus Station	Economy	$47	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/24/2026 11:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 7:15:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 10m
BlaBlaCar Bus	12h 45m	12:25 AM	Karlsruhe	Central Station	1:10 PM	Milan	Lampugnano Bus Station	Economy	$52	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/24/2026 12:25:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 1:10:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 12h 45m
FlixBus	8h 25m	11:40 PM	Karlsruhe	Central Station	8:05 AM	Milan	Lampugnano Bus Station	Economy	$55	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/24/2026 11:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 8:05:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 8h 25m
BlaBlaCar Bus	17h 0m	9:05 PM	Karlsruhe	Central Station	2:05 PM	Milan	Lampugnano Bus Station	Economy	$76	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/24/2026 9:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 2:05:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 17h 0m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 20m	9:30 AM	Karlsruhe	Central Station	4:50 PM	Milan	Lampugnano Bus Station	Economy	$46	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/25/2026 9:30:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 4:50:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 7h 20m
FlixBus	10h 10m	7:40 AM	Karlsruhe	Central Station	5:50 PM	Milan	Lampugnano Bus Station	Economy	$50	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/25/2026 7:40:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 5:50:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 10h 10m
FlixBus	8h 10m	11:05 AM	Karlsruhe	Central Station	7:15 PM	Milan	Lampugnano Bus Station	Economy	$50	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/25/2026 11:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 7:15:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 8h 10m
FlixBus	8h 55m	8:10 PM	Karlsruhe	Central Station	5:05 AM	Milan	Lampugnano Bus Station	Economy	$75	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/25/2026 8:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 5:05:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 8h 55m
FlixBus	7h 55m	3:20 AM	Karlsruhe	Central Station	11:15 AM	Milan	Lampugnano Bus Station	Economy	$86	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/25/2026 3:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 11:15:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 7h 55m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 20m	9:30 AM	Karlsruhe	Central Station	4:50 PM	Milan	Lampugnano Bus Station	Economy	$41	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/27/2026 9:30:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 4:50:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 7h 20m
FlixBus	8h 10m	11:05 AM	Karlsruhe	Central Station	7:15 PM	Milan	Lampugnano Bus Station	Economy	$43	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/27/2026 11:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 7:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 8h 10m
FlixBus	8h 25m	11:40 PM	Karlsruhe	Central Station	8:05 AM	Milan	Lampugnano Bus Station	Economy	$43	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/27/2026 11:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 8:05:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 8h 25m
BlaBlaCar Bus	17h 0m	9:05 PM	Karlsruhe	Central Station	2:05 PM	Milan	Lampugnano Bus Station	Economy	$72	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/27/2026 9:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 2:05:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 17h 0m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	BlaBlaCar Bus	12h 45m	12:25 AM	Karlsruhe	Central Station	1:10 PM	Milan	Lampugnano Bus Station		Economy	$38	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/28/2026 12:25:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 1:10:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 12h 45m
	BlaBlaCar Bus	17h 0m	9:05 PM	Karlsruhe	Central Station	2:05 PM	Milan	Lampugnano Bus Station		Economy	$72	A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/28/2026 9:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 2:05:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 17h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 20m	9:30 AM	Karlsruhe	Central Station	4:50 PM	Milan	Lampugnano Bus Station	Economy	$43	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 9:30:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 4:50:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 7h 20m
FlixBus	8h 10m	11:05 AM	Karlsruhe	Central Station	7:15 PM	Milan	Lampugnano Bus Station	Economy	$46	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 11:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 7:15:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 8h 10m
FlixBus	7h 55m	3:20 AM	Karlsruhe	Central Station	11:15 AM	Milan	Lampugnano Bus Station	Economy	$48	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 3:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 11:15:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 7h 55m
FlixBus	8h 55m	8:10 PM	Karlsruhe	Central Station	5:05 AM	Milan	Lampugnano Bus Station	Economy	$71	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 8:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 5:05:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 8h 55m
FlixBus	8h 10m	11:00 PM	Karlsruhe	Central Station	7:10 AM	Milan	Lampugnano Bus Station	Economy	$112	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 11:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 7:10:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 8h 10m

Best Price Offer: The price for the cheapest bus from Karlsruhe to Milan is $38 on 7/28/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Karlsruhe and Milan

See here how frequent the connections between Karlsruhe and Milan are, during different times and days of the week.

Friday is the busiest day, with more than 9 daily buses from Karlsruhe to Milan. Tuesday has instead the fewest connections, with only 2 daily coaches between Karlsruhe and Milan.

The busiest time of the day is the Evening, with 18 buses from Karlsruhe to Milan, while Night sees the fewest connections between Karlsruhe and Milan, with 6 offers.

Facts about the bus from Karlsruhe to Milan

Compare all providers like FlixBus and BlaBlaCar Bus that travel 5 times every day by bus from Karlsruhe to Milan in one click! Book your bus ticket from Karlsruhe to Milan starting from $38!

Cheapest Bus	$38
Fastest Bus	7h 20m
Earliest Bus	8:10 PM
Latest Bus	11:00 PM
Daily Bus Routes	5 Ø
Distance	247.5 miles
Bus Companies	FlixBus and BlaBlaCar Bus

Cheapest bus connections from Karlsruhe to Milan

Every day, 5 buses from 2 bus companies leave Karlsruhe for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/23/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

$40

Friday 07/24

$46

Saturday 07/25

$46

Sunday 07/26

$47

Monday 07/27

$45

Tuesday 07/28

$38

Wednesday 07/29

$43

Thursday 07/30

$43

Friday 07/31

$47

Saturday 08/01

$58

Sunday 08/02

$51

Monday 08/03

$45

Tuesday 08/04

$43

Wednesday 08/05

$43

Thursday 08/06

$43

Friday 08/07

$108

Saturday 08/08

$48

Sunday 08/09

$48

Monday 08/10

$103

Tuesday 08/11

$48

Wednesday 08/12

$86

Thursday 08/13

Friday 08/14

$46

Saturday 08/15

The cheapest time to travel from Karlsruhe to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Karlsruhe to Milan, for the next 30 days.

With a price starting from $38, Tuesday is the cheapest day for a bus from Karlsruhe to Milan. Friday instead is the most expensive day with prices starting from $46.

Night is the cheapest day time for bus tickets from Karlsruhe to Milan, with $38. Evening is the most expensive time of the day with prices starting from $43.

How to save money travelling from Karlsruhe to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Karlsruhe to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Karlsruhe to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Karlsruhe to Milan are also emptier.

All bus stations and stops in Karlsruhe and Milan

In the map below, you can see where to find all bus stations in Karlsruhe and Milan.

Central Bus Station

Durlach Auer Str./Dr.Willmar Schwabe Bus Stop

Bannwaldallee Station

Kühler Krug Train Station

Sudetenstraße Bus Stop

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Central Bus Station

Duomo Bus Stop

Piazza del Duomo

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Karlsruhe to Milan? Compare all modes of transports from Karlsruhe to Milan.

Service and Comfort on the bus from Karlsruhe to Milan

Want to know which seat classes are available on the buses from Karlsruhe to Milan? Or which bus companies serve the route Karlsruhe to Milan? Below you will find answers to your questions.

FAQs about the Karlsruhe to Milan bus

How much does a Karlsruhe Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $38 and takes 12h 45m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Karlsruhe to Milan?

This route is offered by 2 companies with a range of ticket prices between $38 and $112. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Karlsruhe to Milan each day?

Every day, the Karlsruhe to Milan bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Karlsruhe to Milan take?

The fastest bus from Karlsruhe to Milan is offered by FlixBus and takes 7h 20m. Bus tickets for this connection cost $46. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Karlsruhe to Milan?

The earliest bus arriving in Milan from Karlsruhe starts at 8:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Karlsruhe to Milan?

The latest bus trip departing from Karlsruhe for Milan starts at 11:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Karlsruhe Milan route?

When traveling by bus from Karlsruhe to Milan, passengers can travel with FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Karlsruhe and Milan?

You can check all the direct connections between Karlsruhe and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the Karlsruhe to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Karlsruhe Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Karlsruhe Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Karlsruhe to Milan on your planned travel date.

Available seat classes which are offered on the bus route Karlsruhe to Milan

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Karlsruhe and to Milan

Here’s an overview of the most popular bus routes to Karlsruhe and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!