Bus Houston to Winston-Salem, NC - Compare all Companies

Compare all timetables for the bus from Houston to Winston-Salem, NC

Here is a selection of the cheapest bus trips from the schedule from Houston to Winston-Salem, NC from various bus operators like Greyhound US, FlixBus or Valley Transit for the next days.

today

$124

tomorrow

$119

Monday

$124

Tuesday

$123

Wednesday

$120

Thursday

$122

Friday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	31h 45m	10:00 PM	Houston	Harrisburg Blvd Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station		Economy	$124	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/25/2026 10:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/27/2026 6:45:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 31h 45m
	FlixBus	31h 10m	10:50 PM	Houston	Downtown Houston	7:00 AM	Winston-Salem, NC	Greyhound Bus Station		Economy	$130	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 7/25/2026 10:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/27/2026 7:00:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 31h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	31h 45m	10:00 PM	Houston	Harrisburg Blvd Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$119	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/26/2026 10:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/28/2026 6:45:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 31h 45m
Greyhound US	25h 0m	5:00 AM	Houston	Harrisburg Blvd Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$120	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/26/2026 5:00:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/27/2026 7:00:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 25h 0m
FlixBus	24h 15m	1:30 PM	Houston	Downtown Houston	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$125	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 7/26/2026 1:30:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/27/2026 2:45:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 24h 15m
FlixBus	31h 10m	10:50 PM	Houston	Downtown Houston	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$125	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 7/26/2026 10:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/28/2026 7:00:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 31h 10m
Greyhound US	24h 40m	1:05 PM	Houston	Harrisburg Blvd Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$126	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/26/2026 1:05:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/27/2026 2:45:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 24h 40m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	31h 45m	10:00 PM	Houston	Harrisburg Blvd Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$124	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/27/2026 10:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/29/2026 6:45:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 31h 45m
Valley Transit	47h 10m	6:35 AM	Houston	SW Agencia Autobuses	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$124	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 7/27/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/29/2026 6:45:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 47h 10m
FlixBus	24h 15m	1:30 PM	Houston	Downtown Houston	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$127	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 7/27/2026 1:30:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/28/2026 2:45:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 24h 15m
Greyhound US	24h 40m	1:05 PM	Houston	Harrisburg Blvd Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$128	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/27/2026 1:05:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/28/2026 2:45:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 24h 40m
FlixBus	31h 10m	10:50 PM	Houston	Downtown Houston	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$138	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 7/27/2026 10:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/29/2026 7:00:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 31h 10m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 40m	1:05 PM	Houston	Harrisburg Blvd Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$123	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/28/2026 1:05:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/29/2026 2:45:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 24h 40m
Greyhound US	31h 45m	10:00 PM	Houston	Harrisburg Blvd Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$123	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/28/2026 10:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/30/2026 6:45:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 31h 45m
FlixBus	28h 45m	9:00 AM	Houston	Downtown Houston	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$124	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 7/28/2026 9:00:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/29/2026 2:45:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 28h 45m
FlixBus	47h 10m	6:35 AM	Houston	SW Agencia Autobuses	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$134	A Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 7/28/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/30/2026 6:45:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 47h 10m
Greyhound US	25h 0m	5:00 AM	Houston	Harrisburg Blvd Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$137	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/28/2026 5:00:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/29/2026 7:00:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 25h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	47h 10m	6:35 AM	Houston	SW Agencia Autobuses	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$120	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 7/29/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/31/2026 6:45:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 47h 10m
FlixBus	28h 45m	9:00 AM	Houston	Downtown Houston	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$122	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 7/29/2026 9:00:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/30/2026 2:45:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 28h 45m
Greyhound US	24h 40m	1:05 PM	Houston	Harrisburg Blvd Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$124	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/29/2026 1:05:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/30/2026 2:45:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 24h 40m
Greyhound US	31h 45m	10:00 PM	Houston	Harrisburg Blvd Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$124	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/29/2026 10:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/31/2026 6:45:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 31h 45m
FlixBus	31h 10m	10:50 PM	Houston	Downtown Houston	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$135	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 7/29/2026 10:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/31/2026 7:00:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 31h 10m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	31h 45m	10:00 PM	Houston	Harrisburg Blvd Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$122	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/30/2026 10:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 8/1/2026 6:45:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 31h 45m
Valley Transit	47h 10m	6:35 AM	Houston	SW Agencia Autobuses	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$126	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 7/30/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 8/1/2026 6:45:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 47h 10m
Greyhound US	25h 0m	5:00 AM	Houston	Harrisburg Blvd Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$137	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 7/30/2026 5:00:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/31/2026 7:00:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 25h 0m
FlixBus	24h 15m	1:30 PM	Houston	Downtown Houston	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$137	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 7/30/2026 1:30:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/31/2026 2:45:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 24h 15m
FlixBus	31h 10m	10:50 PM	Houston	Downtown Houston	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$143	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 7/30/2026 10:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 8/1/2026 7:00:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 31h 10m

Best Price Offer: The price for the cheapest bus from Houston to Winston-Salem, NC is $112 on 7/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Houston and Winston-Salem, NC

See here how frequent the connections between Houston and Winston-Salem, NC are, during different times and days of the week.

Monday is the busiest day, with more than 12 daily buses from Houston to Winston-Salem, NC. Saturday has instead the fewest connections, with only 2 daily coaches between Houston and Winston-Salem, NC.

The busiest time of the day is the Evening, with 14 buses from Houston to Winston-Salem, NC, while Night sees the fewest connections between Houston and Winston-Salem, NC, with 6 offers.

Facts about the bus from Houston to Winston-Salem, NC

Compare all providers like Greyhound US, FlixBus and Valley Transit that travel 6 times every day by bus from Houston to Winston-Salem, NC in one click! Book your bus ticket from Houston to Winston-Salem, NC starting from $112!

Cheapest Bus	$112
Fastest Bus	25h 15m
Earliest Bus	10:00 PM
Latest Bus	10:50 PM
Daily Bus Routes	6 Ø
Distance	979.6 miles
Bus Companies	Greyhound US, FlixBus and Valley Transit

Cheapest bus connections from Houston to Winston-Salem, NC

Every day, 6 buses from 3 bus companies leave Houston for Winston-Salem, NC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

Friday 07/24

Saturday 07/25

$124

Sunday 07/26

$115

Monday 07/27

$126

Tuesday 07/28

$123

Wednesday 07/29

$120

Thursday 07/30

$122

Friday 07/31

$116

Saturday 08/01

$130

Sunday 08/02

$120

Monday 08/03

$138

Tuesday 08/04

Wednesday 08/05

$135

Thursday 08/06

Friday 08/07

Saturday 08/08

$118

Sunday 08/09

$117

Monday 08/10

Tuesday 08/11

$124

Wednesday 08/12

$124

Thursday 08/13

Friday 08/14

Saturday 08/15

The cheapest time to travel from Houston to Winston-Salem, NC

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to Winston-Salem, NC, for the next 30 days.

With a price starting from $110, Sunday is the cheapest day for a bus from Houston to Winston-Salem, NC. Monday instead is the most expensive day with prices starting from $124.

Night is the cheapest day time for bus tickets from Houston to Winston-Salem, NC, with $110. Afternoon is the most expensive time of the day with prices starting from $123.

How to save money travelling from Houston to Winston-Salem, NC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to Winston-Salem, NC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to Winston-Salem, NC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to Winston-Salem, NC are also emptier.

All bus stations and stops in Houston and Winston-Salem, NC

In the map below, you can see where to find all bus stations in Houston and Winston-Salem, NC.

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Chase Bank

Milam Street 212

Uptown/Upper Kirby

Southwest Fwy 2525

Greyhound Bus Station

W 5th St 100

Forsyth Hospital

Silas Creek Pkwy 3333

Hong Kong King Buffet

Silas Creek Pkwy 1237

E Sprague St

E Sprague St 841

North Carolina Baptist Hospital

Queen St 2034-2020

Service and Comfort on the bus from Houston to Winston-Salem, NC

Want to know which seat classes are available on the buses from Houston to Winston-Salem, NC? Or which bus companies serve the route Houston to Winston-Salem, NC? Below you will find answers to your questions.

FAQs about the Houston to Winston-Salem, NC bus

How much does a Houston Winston-Salem, NC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $112 and takes 32h 45m to reach Winston-Salem, NC. Compare offers to save money!

How much could I save by comparing buses from Houston to Winston-Salem, NC?

This route is offered by 3 companies with a range of ticket prices between $112 and $158. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Winston-Salem, NC.

On average, how many connections are available from Houston to Winston-Salem, NC each day?

Every day, the Houston to Winston-Salem, NC bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to Winston-Salem, NC take?

The fastest bus from Houston to Winston-Salem, NC is offered by FlixBus and takes 25h 15m. Bus tickets for this connection cost $125. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to Winston-Salem, NC?

The earliest bus arriving in Winston-Salem, NC from Houston starts at 10:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to Winston-Salem, NC?

The latest bus trip departing from Houston for Winston-Salem, NC starts at 10:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston Winston-Salem, NC route?

When traveling by bus from Houston to Winston-Salem, NC, passengers can travel with Greyhound US, FlixBus and Valley Transit. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and Winston-Salem, NC?

You can check all the direct connections between Houston and Winston-Salem, NC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US, FlixBus and Valley Transit.

What can I take with me on the Houston to Winston-Salem, NC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston Winston-Salem, NC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston Winston-Salem, NC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to Winston-Salem, NC on your planned travel date.

Available seat classes which are offered on the bus route Houston to Winston-Salem, NC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to Winston-Salem, NC

Here’s an overview of the most popular bus routes to Houston and to Winston-Salem, NC. Simply click on the connection of your choice, and you will find all the details about your bus route!