Bus McAllen, TX to Winston-Salem, NC

Compare all timetables for the bus from McAllen, TX to Winston-Salem, NC

Here is a selection of the cheapest bus trips from the schedule from McAllen, TX to Winston-Salem, NC from various bus operators like Valley Transit, Greyhound US or Greyhound Lines Mexico for the next days.

today

$118

tomorrow

$120

Tuesday

$126

Wednesday

Thursday

$130

Friday

Saturday

$135

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 25m	11:20 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$118	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/26/2026 11:20:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/28/2026 6:45:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 42h 25m
Valley Transit	38h 45m	11:00 PM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$118	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 7/26/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/28/2026 2:45:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 38h 45m
Valley Transit	38h 10m	3:50 PM	McAllen, TX	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$122	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 7/26/2026 3:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/28/2026 7:00:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 38h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 25m	11:20 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$120	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/27/2026 11:20:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/29/2026 6:45:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 42h 25m
Valley Transit	38h 45m	11:00 PM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$120	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 7/27/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/29/2026 2:45:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 38h 45m
Valley Transit	31h 10m	6:35 AM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$122	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 7/27/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/28/2026 2:45:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 31h 10m
Greyhound US	39h 40m	2:20 PM	McAllen, TX	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$132	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/27/2026 2:20:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/29/2026 7:00:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 39h 40m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	31h 10m	6:35 AM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$126	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 7/28/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/29/2026 2:45:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 31h 10m
Greyhound Lines Mexico	42h 25m	11:20 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$129	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 7/28/2026 11:20:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/30/2026 6:45:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 42h 25m
FlixBus	38h 45m	11:00 PM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$131	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 7/28/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/30/2026 2:45:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 38h 45m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound Lines Mexico	42h 25m	11:20 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station		Economy	$130	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 7/30/2026 11:20:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 8/1/2026 6:45:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 42h 25m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 25m	11:20 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$135	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 8/1/2026 11:20:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 8/3/2026 6:45:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 42h 25m
Valley Transit	31h 10m	6:35 AM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$141	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 8/1/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 8/2/2026 2:45:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 31h 10m
Valley Transit	38h 10m	3:50 PM	McAllen, TX	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$146	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 8/1/2026 3:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 8/3/2026 7:00:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 38h 10m
Valley Transit	38h 45m	11:00 PM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$148	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 8/1/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 8/3/2026 2:45:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 38h 45m

Best Price Offer: The price for the cheapest bus from McAllen, TX to Winston-Salem, NC is $111 on 8/16/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between McAllen, TX and Winston-Salem, NC

See here how frequent the connections between McAllen, TX and Winston-Salem, NC are, during different times and days of the week.

Monday is the busiest day, with more than 7 daily buses from McAllen, TX to Winston-Salem, NC. Thursday has instead the fewest connections, with only 1 daily coaches between McAllen, TX and Winston-Salem, NC.

The busiest time of the day is the Morning, with 10 buses from McAllen, TX to Winston-Salem, NC, while Afternoon sees the fewest connections between McAllen, TX and Winston-Salem, NC, with 4 offers.

Facts about the bus from McAllen, TX to Winston-Salem, NC

Compare all providers like Valley Transit, Greyhound US and Greyhound Lines Mexico that travel 3 times every day by bus from McAllen, TX to Winston-Salem, NC in one click! Book your bus ticket from McAllen, TX to Winston-Salem, NC starting from $111!

Cheapest Bus	$111
Fastest Bus	32h 10m
Earliest Bus	11:20 AM
Latest Bus	11:00 PM
Daily Bus Routes	3 Ø
Distance	1,261.4 miles
Bus Companies	Valley Transit, Greyhound US, Greyhound Lines Mexico and FlixBus

Cheapest bus connections from McAllen, TX to Winston-Salem, NC

Every day, 3 buses from 4 bus companies leave McAllen, TX for Winston-Salem, NC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

$122

Monday 07/27

$124

Tuesday 07/28

$126

Wednesday 07/29

Thursday 07/30

$130

Friday 07/31

Saturday 08/01

$135

Sunday 08/02

Monday 08/03

$120

Tuesday 08/04

$120

Wednesday 08/05

$119

Thursday 08/06

$118

Friday 08/07

$114

Saturday 08/08

$125

Sunday 08/09

Monday 08/10

$120

Tuesday 08/11

$114

Wednesday 08/12

$120

Thursday 08/13

Friday 08/14

Saturday 08/15

Sunday 08/16

$111

Monday 08/17

Tuesday 08/18

Wednesday 08/19

Thursday 08/20

Friday 08/21

Saturday 08/22

The cheapest time to travel from McAllen, TX to Winston-Salem, NC

See here on which day and which time of the day you can find the cheapest bus ticket from McAllen, TX to Winston-Salem, NC, for the next 30 days.

With a price starting from $111, Sunday is the cheapest day for a bus from McAllen, TX to Winston-Salem, NC. Saturday instead is the most expensive day with prices starting from $125.

Morning is the cheapest day time for bus tickets from McAllen, TX to Winston-Salem, NC, with $118. Afternoon is the most expensive time of the day with prices starting from $122.

How to save money travelling from McAllen, TX to Winston-Salem, NC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from McAllen, TX to Winston-Salem, NC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from McAllen, TX to Winston-Salem, NC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from McAllen, TX to Winston-Salem, NC are also emptier.

All bus stations and stops in McAllen, TX and Winston-Salem, NC

In the map below, you can see where to find all bus stations in McAllen, TX and Winston-Salem, NC.

Central Bus Station

U.S. 83 Business 1501

Frontera México-USA

Greyhound Bus Station

W 5th St 100

Forsyth Hospital

Silas Creek Pkwy 3333

Hong Kong King Buffet

Silas Creek Pkwy 1237

E Sprague St

E Sprague St 841

North Carolina Baptist Hospital

Queen St 2034-2020

Service and Comfort on the bus from McAllen, TX to Winston-Salem, NC

Want to know which seat classes are available on the buses from McAllen, TX to Winston-Salem, NC? Or which bus companies serve the route McAllen, TX to Winston-Salem, NC? Below you will find answers to your questions.

FAQs about the McAllen, TX to Winston-Salem, NC bus

How much does a McAllen, TX Winston-Salem, NC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $111 and takes 43h 25m to reach Winston-Salem, NC. Compare offers to save money!

How much could I save by comparing buses from McAllen, TX to Winston-Salem, NC?

This route is offered by 4 companies with a range of ticket prices between $111 and $148. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Winston-Salem, NC.

On average, how many connections are available from McAllen, TX to Winston-Salem, NC each day?

Every day, the McAllen, TX to Winston-Salem, NC bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from McAllen, TX to Winston-Salem, NC take?

The fastest bus from McAllen, TX to Winston-Salem, NC is offered by Valley Transit and takes 32h 10m. Bus tickets for this connection cost $122. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from McAllen, TX to Winston-Salem, NC?

The earliest bus arriving in Winston-Salem, NC from McAllen, TX starts at 11:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from McAllen, TX to Winston-Salem, NC?

The latest bus trip departing from McAllen, TX for Winston-Salem, NC starts at 11:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the McAllen, TX Winston-Salem, NC route?

When traveling by bus from McAllen, TX to Winston-Salem, NC, passengers can travel with Valley Transit, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between McAllen, TX and Winston-Salem, NC?

You can check all the direct connections between McAllen, TX and Winston-Salem, NC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Valley Transit, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the McAllen, TX to Winston-Salem, NC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the McAllen, TX Winston-Salem, NC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the McAllen, TX Winston-Salem, NC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from McAllen, TX to Winston-Salem, NC on your planned travel date.

Available seat classes which are offered on the bus route McAllen, TX to Winston-Salem, NC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to McAllen, TX and to Winston-Salem, NC

Here’s an overview of the most popular bus routes to McAllen, TX and to Winston-Salem, NC. Simply click on the connection of your choice, and you will find all the details about your bus route!