Compare all timetables for the bus from Greenville, SC to Chicago
Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Chicago from various bus operators like FlixBus or Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 21h 30m | 1:20 PM | Greenville, SC | Woodruff Rd | 9:50 AM | Chicago | 95th Red Line Station | Economy | $84 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 9/14/2026 1:20:00 PM to 95th Red Line Station, Chicago (USA) arriving at 9/15/2026 9:50:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 21h 30m
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| Greyhound US | 21h 20m | 2:45 PM | Greenville, SC | Woodruff Rd | 11:05 AM | Chicago | 95th Red Line Station | Economy | $84 |
A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 9/14/2026 2:45:00 PM to 95th Red Line Station, Chicago (USA) arriving at 9/15/2026 11:05:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 21h 20m
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| Greyhound US | 23h 5m | 8:20 PM | Greenville, SC | Woodruff Rd | 6:25 PM | Chicago | 95th Red Line Station | Economy | $85 |
A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 9/14/2026 8:20:00 PM to 95th Red Line Station, Chicago (USA) arriving at 9/15/2026 6:25:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 23h 5m
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| FlixBus | 19h 40m | 1:20 PM | Greenville, SC | Woodruff Rd | 8:00 AM | Chicago | Canal & Van Buren | Economy | $89 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 9/14/2026 1:20:00 PM to Canal & Van Buren, Chicago (USA) arriving at 9/15/2026 8:00:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 19h 40m
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| FlixBus | 20h 5m | 1:20 PM | Greenville, SC | Woodruff Rd | 8:25 AM | Chicago | Downtown Bus Station | Economy | $89 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 9/14/2026 1:20:00 PM to Downtown Bus Station, Chicago (USA) arriving at 9/15/2026 8:25:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 20h 5m
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Test cheapest views
The cheapest bus for the 9/14/2026 costs just $84, from FlixBus
Facts about the bus from Greenville, SC to Chicago
Compare all providers like FlixBus and Greyhound US that travel 22 times every day by bus from Greenville, SC to Chicago in one click! Book your bus ticket from Greenville, SC to Chicago starting from $84!
| Cheapest Bus | $84 |
| Fastest Bus | 18h 40m |
| Earliest Bus | 1:20 PM |
| Latest Bus | 9:35 PM |
| Daily Bus Routes | 22 Ø |
| Distance | 562.3 miles |
| Bus Companies | FlixBus and Greyhound US |
Cheapest bus connections from Greenville, SC to Chicago
Every day, 22 buses from 2 bus companies leave Greenville, SC for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/10/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
09/06
Monday
09/07
Tuesday
09/08
Wednesday
09/09
Thursday
09/10
Friday
09/11
Saturday
09/12
Sunday
09/13
Monday
09/14
$84
Tuesday
09/15
Wednesday
09/16
Thursday
09/17
Friday
09/18
Saturday
09/19
Sunday
09/20
Monday
09/21
$98
Tuesday
09/22
Wednesday
09/23
Thursday
09/24
Friday
09/25
Saturday
09/26
Sunday
09/27
Monday
09/28
Tuesday
09/29
Wednesday
09/30
Thursday
10/01
Friday
10/02
Saturday
10/03
How to save money travelling from Greenville, SC to Chicago
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Greenville, SC to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Chicago, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Chicago are also emptier.All bus stations and stops in Greenville, SC and Chicago
In the map below, you can see where to find all bus stations in Greenville, SC and Chicago.
Service and Comfort on the bus from Greenville, SC to Chicago
Want to know which seat classes are available on the buses from Greenville, SC to Chicago? Or which bus companies serve the route Greenville, SC to Chicago? Below you will find answers to your questions.
FAQs about the Greenville, SC to Chicago bus
How much does a Greenville, SC Chicago bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $84 and takes 20h 30m to reach Chicago. Compare offers to save money!
How much could I save by comparing buses from Greenville, SC to Chicago?
This route is offered by 2 companies with a range of ticket prices between $84 and $106. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.
On average, how many connections are available from Greenville, SC to Chicago each day?
Every day, the Greenville, SC to Chicago bus route is served by approximately 22 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Greenville, SC to Chicago take?
The fastest bus from Greenville, SC to Chicago is offered by FlixBus and takes 18h 40m. Bus tickets for this connection cost $94. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Greenville, SC to Chicago?
The earliest bus arriving in Chicago from Greenville, SC starts at 1:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Greenville, SC to Chicago?
The latest bus trip departing from Greenville, SC for Chicago starts at 9:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Greenville, SC Chicago route?
When traveling by bus from Greenville, SC to Chicago, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Greenville, SC and Chicago?
You can check all the direct connections between Greenville, SC and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.
What can I take with me on the Greenville, SC to Chicago bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Greenville, SC Chicago bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Chicago on your planned travel date.
Available seat classes which are offered on the bus route Greenville, SC to Chicago
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Greenville, SC and to Chicago
Here’s an overview of the most popular bus routes to Greenville, SC and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Greenville, SC
- Bus from Baltimore, MD to Greenville, SC
- Bus Birmingham, AL - Greenville, SC
- Bus from Clarksville, TN to Greenville, SC
- Buses Durham, NC - Greenville, SC
- Buses from Fort Lauderdale, FL to Greenville, SC
- Bus Guadalajara, JC - Greenville, SC
- Buses from Houston to Greenville, SC
- Knoxville, TN to Greenville, SC bus
- Buses from Las Vegas to Greenville, SC
- Buses Milwaukee to Greenville, SC
- Bus from New York to Greenville, SC
- Buses Norfolk, VA - Greenville, SC
- Bus from Phoenix, AZ to Greenville, SC
- Bus from Sacramento to Greenville, SC
- From Santiago de Queretaro to Greenville, SC bus
- Buses from Terre Haute, IN to Greenville, SC
- Buses Tucson, AZ - Greenville, SC
- Bus Warner Robins, GA to Greenville, SC
- Buses Wilmington, DE to Greenville, SC
- Buses to Greenville, SC from Winston-Salem, NC
- Bus Routes to Chicago
- Buses Denver - Chicago
- Bus from Detroit to Chicago
- Buses Eau Claire, WI - Chicago
- Buses El Paso, TX - Chicago
- From Frederick, MD to Chicago bus
- Bus from Houston to Chicago
- Bus from Kansas City to Chicago
- Bus from Lafayette, IN to Chicago
- Bus León de los Aldama - Chicago
- Bus Los Angeles to Chicago
- Buses to Chicago from Montreal
- From Nashville to Chicago bus
- Buses Oklahoma City, OK - Chicago
- Buses from Philadelphia to Chicago
- Buses Phoenix, AZ to Chicago
- Bus Queens Village, NY to Chicago
- From San Antonio, TX to Chicago bus
- Buses to Chicago from Santiago de Queretaro
- Bus from Toronto, ON to Chicago
- Buses from Washington, DC to Chicago
Popular Airport Shuttles to Greenville, SC and to Chicago
