Bus from Frederick, MD to Chicago from $71

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Compare all timetables for the bus from Frederick, MD to Chicago

Here is a selection of the cheapest bus trips from the schedule from Frederick, MD to Chicago from various bus operators like Greyhound US for the next days.
today
$73
tomorrow
$73
Monday
$71
Tuesday
$71
Wednesday
Thursday
Friday
$81

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 25m 7:35 PM Frederick, MD Bus Stop 10:00 AM Chicago Downtown Bus Station  Economy $73
Greyhound US 20h 15m 10:25 AM Frederick, MD Bus Stop 5:40 AM Chicago 95th Red Line Station  Economy $96
Greyhound US 25h 0m 11:35 PM Frederick, MD Bus Stop 11:35 PM Chicago 95th Red Line Station  Economy $96
Greyhound US 20h 45m 10:25 AM Frederick, MD Bus Stop 6:10 AM Chicago Downtown Bus Station  Economy $97
Greyhound US 21h 30m 11:35 PM Frederick, MD Bus Stop 8:05 PM Chicago Downtown Bus Station  Economy $97

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 25m 7:35 PM Frederick, MD Bus Stop 10:00 AM Chicago Downtown Bus Station  Economy $73
Greyhound US 18h 40m 7:35 PM Frederick, MD Bus Stop 1:15 PM Chicago 95th Red Line Station  Economy $89
Greyhound US 20h 15m 10:25 AM Frederick, MD Bus Stop 5:40 AM Chicago 95th Red Line Station  Economy $95
Greyhound US 25h 0m 11:35 PM Frederick, MD Bus Stop 11:35 PM Chicago 95th Red Line Station  Economy $96
Greyhound US 20h 45m 10:25 AM Frederick, MD Bus Stop 6:10 AM Chicago Downtown Bus Station  Economy $97

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 25m 7:35 PM Frederick, MD Bus Stop 10:00 AM Chicago Downtown Bus Station  Economy $71
Greyhound US 22h 35m 10:25 AM Frederick, MD Bus Stop 8:00 AM Chicago Union Station  Economy $101
Greyhound US 20h 45m 10:25 AM Frederick, MD Bus Stop 6:10 AM Chicago Downtown Bus Station  Economy $101
Greyhound US 21h 30m 11:35 PM Frederick, MD Bus Stop 8:05 PM Chicago Downtown Bus Station  Economy $101

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 25m 7:35 PM Frederick, MD Bus Stop 10:00 AM Chicago Downtown Bus Station  Economy $71
Greyhound US 21h 30m 11:35 PM Frederick, MD Bus Stop 8:05 PM Chicago Downtown Bus Station  Economy $101
Greyhound US 27h 55m 5:05 AM Frederick, MD Bus Stop 8:00 AM Chicago Union Station  Economy $109
Greyhound US 28h 20m 5:05 AM Frederick, MD Bus Stop 8:25 AM Chicago Downtown Bus Station  Economy $111
Greyhound US 28h 20m 10:25 AM Frederick, MD Bus Stop 1:45 PM Chicago Union Station  Economy $135

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 25m 7:35 PM Frederick, MD Bus Stop 10:00 AM Chicago Downtown Bus Station  Economy $81
Greyhound US 25h 0m 11:35 PM Frederick, MD Bus Stop 11:35 PM Chicago 95th Red Line Station  Economy $100
Greyhound US 20h 45m 10:25 AM Frederick, MD Bus Stop 6:10 AM Chicago Downtown Bus Station  Economy $101
Greyhound US 21h 30m 11:35 PM Frederick, MD Bus Stop 8:05 PM Chicago Downtown Bus Station  Economy $101
Greyhound US 20h 15m 10:25 AM Frederick, MD Bus Stop 5:40 AM Chicago 95th Red Line Station  Economy $102

Frequency of bus connections between Frederick, MD and Chicago

See here how frequent the connections between Frederick, MD and Chicago are, during different times and days of the week.
Sunday is the busiest day, with more than 11 daily buses from Frederick, MD to Chicago. Monday has instead the fewest connections, with only 4 daily coaches between Frederick, MD and Chicago.
The busiest time of the day is the Evening, with 18 buses from Frederick, MD to Chicago, while Night sees the fewest connections between Frederick, MD and Chicago, with 2 offers.

Test cheapest views

The cheapest bus for the 7/27/2026 costs just $71, from Greyhound US

Facts about the bus from Frederick, MD to Chicago

Compare all providers like Greyhound US that travel 6 times every day by bus from Frederick, MD to Chicago in one click! Book your bus ticket from Frederick, MD to Chicago starting from $71!

Cheapest Bus $71
Fastest Bus 14h 25m
Earliest Bus 10:25 AM
Latest Bus 11:35 PM
Daily Bus Routes 6 Ø
Distance 563.7 miles
Bus Companies Greyhound US

Cheapest bus connections from Frederick, MD to Chicago

Every day, 6 buses from 1 bus companies leave Frederick, MD for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/19
Monday 07/20
Tuesday 07/21
Wednesday 07/22
Thursday 07/23
Friday 07/24
Saturday 07/25
$73
Sunday 07/26
$73
Monday 07/27
$71
Tuesday 07/28
$71
Wednesday 07/29
Thursday 07/30
$100
Friday 07/31
$81
Saturday 08/01
$82
Sunday 08/02
$86
Monday 08/03
Tuesday 08/04
Wednesday 08/05
$100
Thursday 08/06
$100
Friday 08/07
$86
Saturday 08/08
Sunday 08/09
$100
Monday 08/10
$100
Tuesday 08/11
$81
Wednesday 08/12
Thursday 08/13
Friday 08/14
Saturday 08/15

The cheapest time to travel from Frederick, MD to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Frederick, MD to Chicago, for the next 30 days.
With a price starting from $71, Monday is the cheapest day for a bus from Frederick, MD to Chicago. Friday instead is the most expensive day with prices starting from $81.
Evening is the cheapest day time for bus tickets from Frederick, MD to Chicago, with $71. Morning is the most expensive time of the day with prices starting from $95.

How to save money travelling from Frederick, MD to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Frederick, MD to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Frederick, MD to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Frederick, MD to Chicago are also emptier.

All bus stations and stops in Frederick, MD and Chicago

In the map below, you can see where to find all bus stations in Frederick, MD and Chicago.

Service and Comfort on the bus from Frederick, MD to Chicago

Want to know which seat classes are available on the buses from Frederick, MD to Chicago? Or which bus companies serve the route Frederick, MD to Chicago? Below you will find answers to your questions.

FAQs about the Frederick, MD to Chicago bus

How much does a Frederick, MD Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $71 and takes 14h 25m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Frederick, MD to Chicago?

This route is offered by 1 companies with a range of ticket prices between $71 and $136. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Frederick, MD to Chicago each day?

Every day, the Frederick, MD to Chicago bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Frederick, MD to Chicago take?

The fastest bus from Frederick, MD to Chicago is offered by Greyhound US and takes 14h 25m. Bus tickets for this connection cost $73. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Frederick, MD to Chicago?

The earliest bus arriving in Chicago from Frederick, MD starts at 10:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Frederick, MD to Chicago?

The latest bus trip departing from Frederick, MD for Chicago starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Frederick, MD Chicago route?

When traveling by bus from Frederick, MD to Chicago, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Frederick, MD and Chicago?

You can check all the direct connections between Frederick, MD and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Frederick, MD to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Frederick, MD Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Frederick, MD Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Frederick, MD to Chicago on your planned travel date.

Available seat classes which are offered on the bus route Frederick, MD to Chicago

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Frederick, MD and to Chicago

Here’s an overview of the most popular bus routes to Frederick, MD and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!
Albany, NY to Frederick, MD bus Albany, NY to Frederick, MD bus
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Bus to Frederick, MD from Statesville, NC Bus to Frederick, MD from Statesville, NC
Bus Fort Collins, CO - Frederick, MD Bus Fort Collins, CO - Frederick, MD
Southfield, MI to Chicago bus Southfield, MI to Chicago bus
Bus to Chicago from Gary, IN Bus to Chicago from Gary, IN
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Buses Baltimore, MD - Chicago Buses Baltimore, MD - Chicago
Popular Airport Shuttles to Frederick, MD and to Chicago
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