Bus from Florence, SC to Durham, NC from $39

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Compare all timetables for the bus from Florence, SC to Durham, NC

Here is a selection of the cheapest bus trips from the schedule from Florence, SC to Durham, NC from various bus operators like Wanda Coach, Greyhound US or FlixBus for the next days.
today
tomorrow
$60
Monday
$60
Tuesday
$60
Wednesday
$44
Thursday
$39
Friday
$60

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 3h 30m 7:00 PM Florence, SC Shell Gas Station 10:30 PM Durham, NC BP Hillandale Rd  Economy $60
Wanda Coach 3h 30m 9:00 PM Florence, SC Shell Gas Station 12:30 AM Durham, NC BP Hillandale Rd  Economy $60
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $25? You can find the corresponding connections below.
    • Greyhound US
      4h 25m
      0
      5:35 PM
      Florence, SC
      Bus Station
      8:15 PM
      Raleigh, NC
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $29
      • Waiting Time 1h 10m
    • FlixBus
      0h 35m
      0
      9:25 PM
      Raleigh, NC
      Greyhound Bus Station
      10:00 PM
      Durham, NC
      Chapel Hill and Willard St
      0
      FlixBus
      Economy
      $6
    Travel time is 0h 55m longer, but you will save $25

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 3h 30m 7:00 PM Florence, SC Shell Gas Station 10:30 PM Durham, NC BP Hillandale Rd  Economy $60
Wanda Coach 3h 30m 9:00 PM Florence, SC Shell Gas Station 12:30 AM Durham, NC BP Hillandale Rd  Economy $60
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $25? You can find the corresponding connections below.
    • Greyhound US
      4h 25m
      0
      5:35 PM
      Florence, SC
      Bus Station
      8:15 PM
      Raleigh, NC
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $29
      • Waiting Time 1h 10m
    • FlixBus
      0h 35m
      0
      9:25 PM
      Raleigh, NC
      Greyhound Bus Station
      10:00 PM
      Durham, NC
      Chapel Hill and Willard St
      0
      FlixBus
      Economy
      $6
    Travel time is 0h 55m longer, but you will save $25

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 3h 30m 7:00 PM Florence, SC Shell Gas Station 10:30 PM Durham, NC BP Hillandale Rd  Economy $60
Wanda Coach 3h 30m 9:00 PM Florence, SC Shell Gas Station 12:30 AM Durham, NC BP Hillandale Rd  Economy $60
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $25? You can find the corresponding connections below.
    • Greyhound US
      4h 25m
      0
      5:35 PM
      Florence, SC
      Bus Station
      8:15 PM
      Raleigh, NC
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $29
      • Waiting Time 1h 10m
    • FlixBus
      0h 35m
      0
      9:25 PM
      Raleigh, NC
      Greyhound Bus Station
      10:00 PM
      Durham, NC
      Chapel Hill and Willard St
      0
      FlixBus
      Economy
      $6
    Travel time is 0h 55m longer, but you will save $25

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 7h 10m 2:00 PM Florence, SC Bus Station 9:10 PM Durham, NC Exxon  Economy $44
Greyhound US 4h 25m 5:35 PM Florence, SC Bus Station 10:00 PM Durham, NC Exxon  Economy $44
Greyhound US 6h 5m 7:00 PM Florence, SC Bus Station 1:05 AM Durham, NC Exxon  Economy $44
Wanda Coach 3h 30m 7:00 PM Florence, SC Exxon Gas Station 10:30 PM Durham, NC BP Guess Road  Economy $60
Wanda Coach 3h 30m 9:00 PM Florence, SC Exxon Gas Station 12:30 AM Durham, NC BP Guess Road  Economy $60
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $9? You can find the corresponding connections below.
    • Greyhound US
      4h 25m
      0
      5:35 PM
      Florence, SC
      Bus Station
      8:15 PM
      Raleigh, NC
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $29
      • Waiting Time 1h 10m
    • FlixBus
      0h 35m
      0
      9:25 PM
      Raleigh, NC
      Greyhound Bus Station
      10:00 PM
      Durham, NC
      Chapel Hill and Willard St
      0
      FlixBus
      Economy
      $6
    Travel time is 0h 55m longer, but you will save $9

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 4h 25m 5:35 PM Florence, SC Bus Station 10:00 PM Durham, NC Exxon  Economy $39
FlixBus 7h 10m 2:00 PM Florence, SC Bus Station 9:10 PM Durham, NC Exxon  Economy $40
Greyhound US 6h 5m 7:00 PM Florence, SC Bus Station 1:05 AM Durham, NC Exxon  Economy $40
FlixBus 4h 45m 12:05 AM Florence, SC TA Travel Center 4:50 AM Durham, NC Exxon  Economy $45
Wanda Coach 3h 30m 7:00 PM Florence, SC Exxon Gas Station 10:30 PM Durham, NC BP Guess Road  Economy $60
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $4? You can find the corresponding connections below.
    • Greyhound US
      4h 25m
      0
      5:35 PM
      Florence, SC
      Bus Station
      8:15 PM
      Raleigh, NC
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $29
      • Waiting Time 1h 10m
    • FlixBus
      0h 35m
      0
      9:25 PM
      Raleigh, NC
      Greyhound Bus Station
      10:00 PM
      Durham, NC
      Chapel Hill and Willard St
      0
      FlixBus
      Economy
      $6
    Travel time is 0h 55m longer, but you will save $4

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 3h 30m 7:00 PM Florence, SC Shell Gas Station 10:30 PM Durham, NC BP Hillandale Rd  Economy $60
Wanda Coach 3h 30m 9:00 PM Florence, SC Shell Gas Station 12:30 AM Durham, NC BP Hillandale Rd  Economy $60
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $25? You can find the corresponding connections below.
    • Greyhound US
      4h 25m
      0
      5:35 PM
      Florence, SC
      Bus Station
      8:15 PM
      Raleigh, NC
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $29
      • Waiting Time 1h 10m
    • FlixBus
      0h 35m
      0
      9:25 PM
      Raleigh, NC
      Greyhound Bus Station
      10:00 PM
      Durham, NC
      Chapel Hill and Willard St
      0
      FlixBus
      Economy
      $6
    Travel time is 0h 55m longer, but you will save $25

Frequency of bus connections between Florence, SC and Durham, NC

See here how frequent the connections between Florence, SC and Durham, NC are, during different times and days of the week.
Thursday is the busiest day, with more than 8 daily buses from Florence, SC to Durham, NC. Monday has instead the fewest connections, with only 2 daily coaches between Florence, SC and Durham, NC.
The busiest time of the day is the Evening, with 22 buses from Florence, SC to Durham, NC, while Night sees the fewest connections between Florence, SC and Durham, NC, with 1 offers.

Test cheapest views

The cheapest bus for the 7/30/2026 costs just $39, from Greyhound US

Facts about the bus from Florence, SC to Durham, NC

Compare all providers like Wanda Coach, Greyhound US and FlixBus that travel 4 times every day by bus from Florence, SC to Durham, NC in one click! Book your bus ticket from Florence, SC to Durham, NC starting from $39!

Cheapest Bus $39
Fastest Bus 3h 30m
Earliest Bus 7:00 PM
Latest Bus 9:00 PM
Daily Bus Routes 4 Ø
Distance 133.6 miles
Bus Companies Wanda Coach, Greyhound US and FlixBus

Cheapest bus connections from Florence, SC to Durham, NC

Every day, 4 buses from 3 bus companies leave Florence, SC for Durham, NC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/19
Monday 07/20
Tuesday 07/21
Wednesday 07/22
Thursday 07/23
Friday 07/24
Saturday 07/25
$60
Sunday 07/26
$60
Monday 07/27
$60
Tuesday 07/28
Wednesday 07/29
$60
Thursday 07/30
$60
Friday 07/31
$60
Saturday 08/01
$60
Sunday 08/02
$60
Monday 08/03
$60
Tuesday 08/04
Wednesday 08/05
$60
Thursday 08/06
$63
Friday 08/07
$60
Saturday 08/08
$60
Sunday 08/09
$60
Monday 08/10
$60
Tuesday 08/11
$60
Wednesday 08/12
$60
Thursday 08/13
Friday 08/14
Saturday 08/15

The cheapest time to travel from Florence, SC to Durham, NC

See here on which day and which time of the day you can find the cheapest bus ticket from Florence, SC to Durham, NC, for the next 30 days.
With a price starting from $39, Thursday is the cheapest day for a bus from Florence, SC to Durham, NC. Monday instead is the most expensive day with prices starting from $59.
Afternoon is the cheapest day time for bus tickets from Florence, SC to Durham, NC, with $39. Night is the most expensive time of the day with prices starting from $45.

How to save money travelling from Florence, SC to Durham, NC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Florence, SC to Durham, NC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Florence, SC to Durham, NC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Florence, SC to Durham, NC are also emptier.

All bus stations and stops in Florence, SC and Durham, NC

In the map below, you can see where to find all bus stations in Florence, SC and Durham, NC.

Service and Comfort on the bus from Florence, SC to Durham, NC

Want to know which seat classes are available on the buses from Florence, SC to Durham, NC? Or which bus companies serve the route Florence, SC to Durham, NC? Below you will find answers to your questions.

FAQs about the Florence, SC to Durham, NC bus

How much does a Florence, SC Durham, NC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $39 and takes 4h 25m to reach Durham, NC. Compare offers to save money!

How much could I save by comparing buses from Florence, SC to Durham, NC?

This route is offered by 3 companies with a range of ticket prices between $39 and $60. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Durham, NC.

On average, how many connections are available from Florence, SC to Durham, NC each day?

Every day, the Florence, SC to Durham, NC bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Florence, SC to Durham, NC take?

The fastest bus from Florence, SC to Durham, NC is offered by Wanda Coach and takes 3h 30m. Bus tickets for this connection cost $60. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Florence, SC to Durham, NC?

The earliest bus arriving in Durham, NC from Florence, SC starts at 7:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Florence, SC to Durham, NC?

The latest bus trip departing from Florence, SC for Durham, NC starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Florence, SC Durham, NC route?

When traveling by bus from Florence, SC to Durham, NC, passengers can travel with Wanda Coach, Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Florence, SC and Durham, NC?

You can check all the direct connections between Florence, SC and Durham, NC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Wanda Coach, Greyhound US and FlixBus.

What can I take with me on the Florence, SC to Durham, NC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Florence, SC Durham, NC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Florence, SC Durham, NC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Florence, SC to Durham, NC on your planned travel date.

Available seat classes which are offered on the bus route Florence, SC to Durham, NC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Florence, SC and to Durham, NC

Here’s an overview of the most popular bus routes to Florence, SC and to Durham, NC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Florence, SC and to Durham, NC
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