Which bus from Antofagasta to Santiago, RM is the cheapest?

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Compare all timetables for the bus from Antofagasta to Santiago, RM

Here is a selection of the cheapest bus trips from the schedule from Antofagasta to Santiago, RM from various bus operators like Pullman San Andres, Cikbus Elité or Pullman Bus for the next days.

today
$31
tomorrow
$32
Wednesday
$33
Thursday
$32
Friday
$32
Saturday
$31
Sunday
$36

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 19h 35m 6:20 PM Antofagasta Carlos Oviedo Cavada Bus Station 1:55 PM Santiago, RM Terminal San Borja  Economy $31
Cormar Bus 18h 11m 11:59 PM Antofagasta Camus Bus Station 6:10 PM Santiago, RM Terminal San Borja  Premium Economy $37
Pullman San Andres 18h 30m 1:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 7:30 AM Santiago, RM Terminal San Borja  Premium Economy $42
Buses Norte Azul 16h 55m 6:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 11:25 PM Santiago, RM Terminal San Borja  Premium Economy $47
Pullman Bus 20h 0m 1:00 AM Antofagasta Camus Bus Station 9:00 PM Santiago, RM Terminal San Borja  First Class $58
  • Did you know that if you travel from Antofagasta to Santiago, RM via Vallenar, you can save more than $7? You can find the corresponding connections below.
    • FlixBus
      22h 25m
      0
      6:20 PM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      3:40 AM
      Vallenar
      Bus Station
      0
      FlixBus
      Economy
      $21
      • Waiting Time 3h 50m
    • Pullman San Andres
      9h 15m
      0
      7:30 AM
      Vallenar
      Bus Stop
      4:45 PM
      Santiago, RM
      Terminal San Borja
      0
      Pullman San Andres
      First Class
      $3
    Travel time is 5h 30m longer, but you will save $7

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 0m 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 7:35 PM Santiago, RM Terminal San Borja  Economy $32
Pullman San Andres 18h 30m 1:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 7:30 AM Santiago, RM Terminal San Borja  Premium Economy $36
Cormar Bus 18h 30m 2:00 PM Antofagasta Camus Bus Station 8:30 AM Santiago, RM Terminal San Borja  Premium Economy $39
Chile Bus 19h 0m 11:30 PM Antofagasta Carlos Oviedo Cavada Bus Station 6:30 PM Santiago, RM Terminal San Borja  First Class $47
Pullman Bus 20h 0m 1:00 AM Antofagasta Camus Bus Station 9:00 PM Santiago, RM Terminal San Borja  First Class $58
  • Did you know that if you travel from Antofagasta to Santiago, RM via Vallenar, you can save more than $8? You can find the corresponding connections below.
    • FlixBus
      22h 25m
      0
      6:20 PM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      3:40 AM
      Vallenar
      Bus Station
      0
      FlixBus
      Economy
      $21
      • Waiting Time 3h 50m
    • Pullman San Andres
      9h 15m
      0
      7:30 AM
      Vallenar
      Bus Stop
      4:45 PM
      Santiago, RM
      Terminal San Borja
      0
      Pullman San Andres
      First Class
      $3
    Travel time is 4h 25m longer, but you will save $8

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 0m 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 7:35 PM Santiago, RM Terminal San Borja  Economy $33
Cormar Bus 18h 30m 1:00 AM Antofagasta Camus Bus Station 7:30 PM Santiago, RM Terminal San Borja  Premium Economy $35
Cikbus Elité 18h 50m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 10:20 PM Santiago, RM Terminal San Borja  Business $37
Pluss Chile 17h 30m 12:05 AM Antofagasta Carlos Oviedo Cavada Bus Station 5:35 PM Santiago, RM Sur Bus Station  Premium Economy $38
Pullman San Andres 18h 30m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 PM Santiago, RM Terminal San Borja  Premium Economy $45
  • Did you know that if you travel from Antofagasta to Santiago, RM via Vallenar, you can save more than $9? You can find the corresponding connections below.
    • FlixBus
      22h 25m
      0
      6:20 PM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      3:40 AM
      Vallenar
      Bus Station
      0
      FlixBus
      Economy
      $21
      • Waiting Time 3h 50m
    • Pullman San Andres
      9h 15m
      0
      7:30 AM
      Vallenar
      Bus Stop
      4:45 PM
      Santiago, RM
      Terminal San Borja
      0
      Pullman San Andres
      First Class
      $3
    Travel time is 4h 55m longer, but you will save $9

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 0m 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 7:35 PM Santiago, RM Terminal San Borja  Economy $32
Cormar Bus 18h 30m 1:00 AM Antofagasta Camus Bus Station 7:30 PM Santiago, RM Terminal San Borja  Premium Economy $35
Pullman San Andres 18h 30m 1:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 7:30 AM Santiago, RM Terminal San Borja  Premium Economy $36
Nueva Andimar Vip 21h 5m 11:20 PM Antofagasta Carlos Oviedo Cavada Bus Station 8:25 PM Santiago, RM Los Libertadores Bus Stop  Economy $44
Pullman Bus 20h 0m 1:00 AM Antofagasta Camus Bus Station 9:00 PM Santiago, RM Terminal San Borja  First Class $58
  • Did you know that if you travel from Antofagasta to Santiago, RM via Vallenar, you can save more than $8? You can find the corresponding connections below.
    • FlixBus
      22h 25m
      0
      6:20 PM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      3:40 AM
      Vallenar
      Bus Station
      0
      FlixBus
      Economy
      $21
      • Waiting Time 3h 50m
    • Pullman San Andres
      9h 15m
      0
      7:30 AM
      Vallenar
      Bus Stop
      4:45 PM
      Santiago, RM
      Terminal San Borja
      0
      Pullman San Andres
      First Class
      $3
    Travel time is 4h 25m longer, but you will save $8

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 19h 35m 9:50 PM Antofagasta Carlos Oviedo Cavada Bus Station 5:25 PM Santiago, RM Terminal San Borja  Economy $32
FlixBus 18h 0m 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 7:35 PM Santiago, RM Terminal San Borja  Economy $34
Pullman San Andres 18h 30m 1:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 7:30 AM Santiago, RM Terminal San Borja  Premium Economy $36
Cormar Bus 18h 11m 11:59 PM Antofagasta Camus Bus Station 6:10 PM Santiago, RM Terminal San Borja  Premium Economy $37
Pluss Chile 17h 30m 12:05 AM Antofagasta Carlos Oviedo Cavada Bus Station 5:35 PM Santiago, RM Sur Bus Station  Premium Economy $38
  • Did you know that if you travel from Antofagasta to Santiago, RM via Vallenar, you can save more than $8? You can find the corresponding connections below.
    • FlixBus
      22h 25m
      0
      6:20 PM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      3:40 AM
      Vallenar
      Bus Station
      0
      FlixBus
      Economy
      $21
      • Waiting Time 3h 50m
    • Pullman San Andres
      9h 15m
      0
      7:30 AM
      Vallenar
      Bus Stop
      4:45 PM
      Santiago, RM
      Terminal San Borja
      0
      Pullman San Andres
      First Class
      $3
    Travel time is 4h 55m longer, but you will save $8

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 0m 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 7:35 PM Santiago, RM Terminal San Borja  Economy $31
FlixBus 18h 0m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 9:35 PM Santiago, RM Terminal San Borja  Economy $31
Cormar Bus 18h 11m 11:59 PM Antofagasta Camus Bus Station 6:10 PM Santiago, RM Terminal San Borja  Premium Economy $37
Cormar Bus 18h 30m 2:00 PM Antofagasta Camus Bus Station 8:30 AM Santiago, RM Terminal San Borja  Premium Economy $39
Pullman San Andres 18h 30m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 PM Santiago, RM Terminal San Borja  Premium Economy $45
  • Did you know that if you travel from Antofagasta to Santiago, RM via Vallenar, you can save more than $7? You can find the corresponding connections below.
    • FlixBus
      22h 25m
      0
      6:20 PM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      3:40 AM
      Vallenar
      Bus Station
      0
      FlixBus
      Economy
      $21
      • Waiting Time 3h 50m
    • Pullman San Andres
      9h 15m
      0
      7:30 AM
      Vallenar
      Bus Stop
      4:45 PM
      Santiago, RM
      Terminal San Borja
      0
      Pullman San Andres
      First Class
      $3
    Travel time is 4h 25m longer, but you will save $7

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 0m 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 7:35 PM Santiago, RM Terminal San Borja  Economy $36
Cormar Bus 18h 11m 11:59 PM Antofagasta Camus Bus Station 6:10 PM Santiago, RM Terminal San Borja  Premium Economy $37
Cikbus Elité 21h 0m 8:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 5:30 AM Santiago, RM Sur Bus Station  Premium Economy $42
Pullman San Andres 18h 30m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 PM Santiago, RM Terminal San Borja  Premium Economy $45
Pullman Bus 20h 0m 1:00 AM Antofagasta Camus Bus Station 9:00 PM Santiago, RM Terminal San Borja  First Class $58
  • Did you know that if you travel from Antofagasta to Santiago, RM via Vallenar, you can save more than $12? You can find the corresponding connections below.
    • FlixBus
      22h 25m
      0
      6:20 PM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      3:40 AM
      Vallenar
      Bus Station
      0
      FlixBus
      Economy
      $21
      • Waiting Time 3h 50m
    • Pullman San Andres
      9h 15m
      0
      7:30 AM
      Vallenar
      Bus Stop
      4:45 PM
      Santiago, RM
      Terminal San Borja
      0
      Pullman San Andres
      First Class
      $3
    Travel time is 4h 25m longer, but you will save $12

Best Price Offer: The price for the cheapest bus from Antofagasta to Santiago, RM is $31 on 7/26/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Antofagasta and Santiago, RM

See here how frequent the connections between Antofagasta and Santiago, RM are, during different times and days of the week.
Wednesday is the busiest day, with more than 150 daily buses from Antofagasta to Santiago, RM. Monday has instead the fewest connections, with only 44 daily coaches between Antofagasta and Santiago, RM.
The busiest time of the day is the Evening, with 200 buses from Antofagasta to Santiago, RM, while Morning sees the fewest connections between Antofagasta and Santiago, RM, with 48 offers.

Facts about the bus from Antofagasta to Santiago, RM

Compare all providers like Pullman San Andres, Cikbus Elité and Pullman Bus that travel 69 times every day by bus from Antofagasta to Santiago, RM in one click! Book your bus ticket from Antofagasta to Santiago, RM starting from $31!

Cheapest Bus $31
Fastest Bus 16h 55m
Earliest Bus 1:00 AM
Latest Bus 11:59 PM
Daily Bus Routes 69 Ø
Distance 677.0 miles
Bus Companies Pullman San Andres, Cikbus Elité, Pullman Bus, Pluss Chile, FlixBus, Nueva Andimar Vip, Cormar Bus, Buses Norte Azul and Chile Bus

Cheapest bus connections from Antofagasta to Santiago, RM

Every day, 69 buses from 9 bus companies leave Antofagasta for Santiago, RM: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/26
Monday 07/27
$37
Tuesday 07/28
$31
Wednesday 07/29
$31
Thursday 07/30
$34
Friday 07/31
$31
Saturday 08/01
$34
Sunday 08/02
$38
Monday 08/03
$33
Tuesday 08/04
$32
Wednesday 08/05
$32
Thursday 08/06
$32
Friday 08/07
$38
Saturday 08/08
$33
Sunday 08/09
$35
Monday 08/10
$31
Tuesday 08/11
$31
Wednesday 08/12
$31
Thursday 08/13
$33
Friday 08/14
$35
Saturday 08/15
$32
Sunday 08/16
$32
Monday 08/17
$32
Tuesday 08/18
$31
Wednesday 08/19
$31
Thursday 08/20
$31
Friday 08/21
$32
Saturday 08/22

The cheapest time to travel from Antofagasta to Santiago, RM

See here on which day and which time of the day you can find the cheapest bus ticket from Antofagasta to Santiago, RM, for the next 30 days.
With a price starting from $31, Monday is the cheapest day for a bus from Antofagasta to Santiago, RM. Sunday instead is the most expensive day with prices starting from $32.
Evening is the cheapest day time for bus tickets from Antofagasta to Santiago, RM, with $31. Morning is the most expensive time of the day with prices starting from $37.

How to save money travelling from Antofagasta to Santiago, RM

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Antofagasta to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Antofagasta to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Antofagasta to Santiago, RM are also emptier.

Beloved bus companies from Antofagasta to Santiago, RM

These are the most booked bus companies between Antofagasta to Santiago, RM from our users.

Pullman San Andres from Antofagasta to Santiago, RM

Pullman San Andres

Here you will find the key facts about the Pullman San Andres bus route Antofagasta to Santiago, RM:

Cheapest Price $36
Fastest Bus 18h 25m
Earliest Bus 1:30 AM
Last Bus 11:30 PM
Daily Connections 26 Ø
Found on 7/16/2026

Cormar Bus from Antofagasta to Santiago, RM

Cormar Bus

Here you will find the key facts about the Cormar Bus bus route Antofagasta to Santiago, RM:

Cheapest Price $35
Fastest Bus 17h 50m
Earliest Bus 1:00 PM
Last Bus 11:59 PM
Daily Connections 4 Ø
Found on 7/16/2026

All bus stations and stops in Antofagasta and Santiago, RM

In the map below, you can see where to find all bus stations in Antofagasta and Santiago, RM.

Service and Comfort on the bus from Antofagasta to Santiago, RM

Want to know which seat classes are available on the buses from Antofagasta to Santiago, RM? Or which bus companies serve the route Antofagasta to Santiago, RM? Below you will find answers to your questions.

FAQs about the Antofagasta to Santiago, RM bus

How much does a Antofagasta Santiago, RM bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $31 and takes 19h 35m to reach Santiago, RM. Compare offers to save money!

How much could I save by comparing buses from Antofagasta to Santiago, RM?

This route is offered by 9 companies with a range of ticket prices between $31 and $70. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago, RM.

On average, how many connections are available from Antofagasta to Santiago, RM each day?

Every day, the Antofagasta to Santiago, RM bus route is served by approximately 69 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Antofagasta to Santiago, RM take?

The fastest bus from Antofagasta to Santiago, RM is offered by Buses Norte Azul and takes 16h 55m. Bus tickets for this connection cost $47. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Antofagasta to Santiago, RM?

The earliest bus arriving in Santiago, RM from Antofagasta starts at 1:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Antofagasta to Santiago, RM?

The latest bus trip departing from Antofagasta for Santiago, RM starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Antofagasta Santiago, RM route?

When traveling by bus from Antofagasta to Santiago, RM, passengers can travel with Pullman San Andres, Cikbus Elité and Pullman Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Antofagasta and Santiago, RM?

You can check all the direct connections between Antofagasta and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pullman San Andres, Cikbus Elité and Pullman Bus.

What can I take with me on the Antofagasta to Santiago, RM bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Antofagasta Santiago, RM bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Antofagasta Santiago, RM bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Antofagasta to Santiago, RM on your planned travel date.

Available seat classes which are offered on the bus route Antofagasta to Santiago, RM

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Antofagasta and to Santiago, RM

Here’s an overview of the most popular bus routes to Antofagasta and to Santiago, RM. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus San Pedro de Atacama - Antofagasta Bus San Pedro de Atacama - Antofagasta
Buses Pozo Almonte - Antofagasta Buses Pozo Almonte - Antofagasta
Bus to Antofagasta from Los Vilos Bus to Antofagasta from Los Vilos
Bus La Calera - Antofagasta Bus La Calera - Antofagasta
Cartagena (CL) to Santiago, RM bus Cartagena (CL) to Santiago, RM bus
Bus Graneros - Santiago, RM Bus Graneros - Santiago, RM
Bus Collipulli - Santiago, RM Bus Collipulli - Santiago, RM
Bus from Concepción to Santiago, RM Bus from Concepción to Santiago, RM
Popular Airport Shuttles to Antofagasta and to Santiago, RM
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