Compare all timetables for the bus from Antofagasta to Santiago, RM
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pluss Chile | 18h 20m | 10:30 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | 4:50 AM | Santiago, RM | Sur Bus Station | Premium Economy | $40 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/10/2026 10:30:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 4:50:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 18h 20m
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| Pluss Chile | 18h 5m | 3:15 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | 9:20 AM | Santiago, RM | Sur Bus Station | Premium Economy | $40 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/10/2026 3:15:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 9:20:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 18h 5m
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| Pluss Chile | 17h 30m | 3:30 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | 9:00 AM | Santiago, RM | Sur Bus Station | Premium Economy | $40 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/10/2026 3:30:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 9:00:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 17h 30m
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| Cikbus Elité | 21h 0m | 8:30 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | 5:30 AM | Santiago, RM | Sur Bus Station | Premium Economy | $43 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/10/2026 8:30:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 5:30:00 AM. 50 Premium Economy ticket for $43 per person are available. Travel duration is 21h 0m
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| Cikbus Elité | 18h 50m | 10:10 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | 5:00 PM | Santiago, RM | Sur Bus Station | Premium Economy | $43 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/10/2026 10:10:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 5:00:00 PM. 50 Premium Economy ticket for $43 per person are available. Travel duration is 18h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pullman Bus | 20h 0m | 1:00 AM | Antofagasta | Camus Bus Station | 9:00 PM | Santiago, RM | Terminal San Borja | First Class | $32 |
A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/11/2026 1:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/11/2026 9:00:00 PM. 50 First Class ticket for $32 per person are available. Travel duration is 20h 0m
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| Cormar Bus | 18h 25m | 11:45 PM | Antofagasta | Camus Bus Station | 6:10 PM | Santiago, RM | Terminal San Borja | Premium Economy | $38 |
A Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/11/2026 11:45:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/12/2026 6:10:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 25m
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| Pluss Chile | 17h 30m | 12:05 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | 5:35 PM | Santiago, RM | Sur Bus Station | Premium Economy | $40 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/11/2026 12:05:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 5:35:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 17h 30m
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| Pullman San Andres | 18h 30m | 3:30 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:00 PM | Santiago, RM | Terminal San Borja | Premium Economy | $46 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/11/2026 3:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/11/2026 10:00:00 PM. 50 Premium Economy ticket for $46 per person are available. Travel duration is 18h 30m
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| FlixBus | 18h 0m | 1:35 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | 7:35 PM | Santiago, RM | Terminal San Borja | Economy | $48 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/11/2026 1:35:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/11/2026 7:35:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 18h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pullman Bus | 20h 0m | 1:00 AM | Antofagasta | Camus Bus Station | 9:00 PM | Santiago, RM | Terminal San Borja | First Class | $32 |
A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/12/2026 1:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/12/2026 9:00:00 PM. 50 First Class ticket for $32 per person are available. Travel duration is 20h 0m
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| Cikbus Elité | 21h 0m | 8:30 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | 5:30 AM | Santiago, RM | Terminal San Borja | Premium Economy | $37 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/12/2026 8:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/13/2026 5:30:00 AM. 50 Premium Economy ticket for $37 per person are available. Travel duration is 21h 0m
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| Cormar Bus | 18h 25m | 11:45 PM | Antofagasta | Camus Bus Station | 6:10 PM | Santiago, RM | Terminal San Borja | Premium Economy | $38 |
A Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/12/2026 11:45:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/13/2026 6:10:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 25m
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| Pullman San Andres | 18h 30m | 11:30 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | 6:00 PM | Santiago, RM | Terminal San Borja | Premium Economy | $46 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/12/2026 11:30:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/13/2026 6:00:00 PM. 50 Premium Economy ticket for $46 per person are available. Travel duration is 18h 30m
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| FlixBus | 19h 35m | 9:50 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | 5:25 PM | Santiago, RM | Terminal San Borja | Economy | $48 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/12/2026 9:50:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/13/2026 5:25:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 19h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pullman Bus | 20h 0m | 1:00 AM | Antofagasta | Camus Bus Station | 9:00 PM | Santiago, RM | Terminal San Borja | First Class | $32 |
A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/13/2026 1:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/13/2026 9:00:00 PM. 50 First Class ticket for $32 per person are available. Travel duration is 20h 0m
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| Pullman Bus | 19h 15m | 11:30 AM | Antofagasta | Camus Bus Station | 6:45 AM | Santiago, RM | Terminal San Borja | First Class | $32 |
A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/13/2026 11:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/14/2026 6:45:00 AM. 50 First Class ticket for $32 per person are available. Travel duration is 19h 15m
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| Cormar Bus | 18h 25m | 11:45 PM | Antofagasta | Camus Bus Station | 6:10 PM | Santiago, RM | Terminal San Borja | Premium Economy | $38 |
A Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/13/2026 11:45:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/14/2026 6:10:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 25m
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| Cormar Bus | 19h 0m | 1:50 PM | Antofagasta | Camus Bus Station | 8:50 AM | Santiago, RM | Terminal San Borja | Premium Economy | $40 |
A Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/13/2026 1:50:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/14/2026 8:50:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 19h 0m
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| Pullman San Andres | 18h 30m | 11:30 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | 6:00 PM | Santiago, RM | Terminal San Borja | Premium Economy | $46 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/13/2026 11:30:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/14/2026 6:00:00 PM. 50 Premium Economy ticket for $46 per person are available. Travel duration is 18h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pullman Bus | 20h 0m | 1:00 AM | Antofagasta | Camus Bus Station | 9:00 PM | Santiago, RM | Terminal San Borja | First Class | $32 |
A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/15/2026 1:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/15/2026 9:00:00 PM. 50 First Class ticket for $32 per person are available. Travel duration is 20h 0m
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| Cormar Bus | 19h 0m | 1:50 PM | Antofagasta | Camus Bus Station | 8:50 AM | Santiago, RM | Terminal San Borja | Premium Economy | $40 |
A Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/15/2026 1:50:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/16/2026 8:50:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 19h 0m
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| Pullman San Andres | 18h 30m | 11:30 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | 6:00 PM | Santiago, RM | Terminal San Borja | Premium Economy | $46 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/15/2026 11:30:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/16/2026 6:00:00 PM. 50 Premium Economy ticket for $46 per person are available. Travel duration is 18h 30m
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| FlixBus | 18h 50m | 3:00 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | 9:50 PM | Santiago, RM | Terminal San Borja | Economy | $48 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/15/2026 3:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/15/2026 9:50:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 18h 50m
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| Chile Bus | 19h 0m | 11:30 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | 6:30 PM | Santiago, RM | Terminal San Borja | First Class | $49 |
A Bus from Chile Bus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/15/2026 11:30:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/16/2026 6:30:00 PM. 50 First Class ticket for $49 per person are available. Travel duration is 19h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pullman Bus | 20h 0m | 1:00 AM | Antofagasta | Camus Bus Station | 9:00 PM | Santiago, RM | Terminal San Borja | First Class | $32 |
A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/16/2026 1:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/16/2026 9:00:00 PM. 50 First Class ticket for $32 per person are available. Travel duration is 20h 0m
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| Pullman Bus | 19h 15m | 11:30 AM | Antofagasta | Camus Bus Station | 6:45 AM | Santiago, RM | Terminal San Borja | First Class | $32 |
A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 9/16/2026 11:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/17/2026 6:45:00 AM. 50 First Class ticket for $32 per person are available. Travel duration is 19h 15m
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| Pullman San Andres | 18h 30m | 11:30 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | 6:00 PM | Santiago, RM | Terminal San Borja | Premium Economy | $46 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/16/2026 11:30:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/17/2026 6:00:00 PM. 50 Premium Economy ticket for $46 per person are available. Travel duration is 18h 30m
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| FlixBus | 18h 50m | 3:00 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | 9:50 PM | Santiago, RM | Terminal San Borja | Economy | $49 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/16/2026 3:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/16/2026 9:50:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 18h 50m
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| Nueva Andimar Vip | 18h 0m | 1:35 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | 7:35 PM | Santiago, RM | Terminal San Borja | Economy | $50 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 9/16/2026 1:35:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 9/16/2026 7:35:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 18h 0m
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Best Price Offer: The price for the cheapest bus from Antofagasta to Santiago, RM is $31 on 9/8/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Antofagasta and Santiago, RM
Facts about the bus from Antofagasta to Santiago, RM
Compare all providers like Pullman San Andres, Pluss Chile and Pullman Bus that travel 46 times every day by bus from Antofagasta to Santiago, RM in one click! Book your bus ticket from Antofagasta to Santiago, RM starting from $31!
| Cheapest Bus | $31 |
| Fastest Bus | 17h 5m |
| Earliest Bus | 8:30 AM |
| Latest Bus | 11:30 PM |
| Daily Bus Routes | 46 Ø |
| Distance | 677.0 miles |
| Bus Companies | Pullman San Andres, Pluss Chile, Pullman Bus, FlixBus, Nueva Andimar Vip, Cikbus Elité, Cormar Bus and Chile Bus |
Cheapest bus connections from Antofagasta to Santiago, RM
Every day, 46 buses from 8 bus companies leave Antofagasta for Santiago, RM: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/10/2026 and for the following days.
The cheapest time to travel from Antofagasta to Santiago, RM
How to save money travelling from Antofagasta to Santiago, RM
Book the ticket from Antofagasta to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Antofagasta to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Antofagasta to Santiago, RM are also emptier.Latest reviews for bus companies on the route Antofagasta - Santiago, RM
All bus stations and stops in Antofagasta and Santiago, RM
In the map below, you can see where to find all bus stations in Antofagasta and Santiago, RM.
Service and Comfort on the bus from Antofagasta to Santiago, RM
FAQs about the Antofagasta to Santiago, RM bus
How much does a Antofagasta Santiago, RM bus trip cost?
How much could I save by comparing buses from Antofagasta to Santiago, RM?
On average, how many connections are available from Antofagasta to Santiago, RM each day?
How long does a bus journey from Antofagasta to Santiago, RM take?
What time is the first bus from Antofagasta to Santiago, RM?
What time is the last bus from Antofagasta to Santiago, RM?
Which bus companies operate the Antofagasta Santiago, RM route?
Is there a direct bus between Antofagasta and Santiago, RM?
What can I take with me on the Antofagasta to Santiago, RM bus route?
What equipment is available for the Antofagasta Santiago, RM bus route?
Available seat classes which are offered on the bus route Antofagasta to Santiago, RM
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to Antofagasta and to Santiago, RM
- Bus Routes to Antofagasta
- Buses Alto Hospicio to Antofagasta
- Bus Arica, AP to Antofagasta
- From Calama to Antofagasta bus
- Buses from Concepción to Antofagasta
- Bus Copiapó - Antofagasta
- From Coquimbo to Antofagasta bus
- Bus Iquique to Antofagasta
- Buses La Serena - Antofagasta
- Bus to Antofagasta from Los Vilos
- Buses to Antofagasta from Oruro
- Buses to Antofagasta from Ovalle
- Buses Pozo Almonte - Antofagasta
- From Temuco to Antofagasta bus
- Tocopilla to Antofagasta bus
- Buses from Valparaíso (CL) to Antofagasta
- Bus Routes to Santiago, RM
- Buses from Angol to Santiago, RM
- Bus to Santiago, RM from Arica, AP
- Calama to Santiago, RM bus
- Cartagena (CL) to Santiago, RM bus
- Castro to Santiago, RM bus
- From Chillán to Santiago, RM bus
- Bus from Concepción to Santiago, RM
- Coquimbo to Santiago, RM bus
- Buses to Santiago, RM from Coyhaique
- Buses Iquique to Santiago, RM
- Buses La Serena to Santiago, RM
- Bus Lautaro - Santiago, RM
- Bus Lota to Santiago, RM
- Buses from Nueva Imperial to Santiago, RM
- Buses from Osorno, LL to Santiago, RM
- Bus Pitrufquén - Santiago, RM
- Bus to Santiago, RM from Quilpué
- Bus Talca, ML to Santiago, RM
- Buses Valdivia - Santiago, RM
- Vallenar to Santiago, RM bus
