Bus São Paulo to Santa Cruz de la Sierra: Compare prices and save money

Compare all timetables for the bus from São Paulo to Santa Cruz de la Sierra

Here is a selection of the cheapest bus trips from the schedule from São Paulo to Santa Cruz de la Sierra from various bus operators like La Preferida Bus for the next days.

today

tomorrow

Wednesday

$199

Thursday

Friday

Saturday

Sunday

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	La Preferida Bus	39h 30m	1:00 PM	São Paulo	Barra Funda Bus Station	3:30 AM	Santa Cruz de la Sierra	Terminal Bimodal		First Class	$199	A Bus from La Preferida Bus goes from Barra Funda Bus Station, São Paulo (Brazil) at 7/29/2026 1:00:00 PM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 7/31/2026 3:30:00 AM. 50 First Class ticket for $199 per person are available. Travel duration is 39h 30m

Did you know that if you travel from São Paulo to Santa Cruz de la Sierra via Puerto Quijarro, you can save more than $69? You can find the corresponding connections below.
- La Preferida Bus
  
  55h 30m
  
  0
  
  1:00 PM
  
  São Paulo
  Barra Funda Bus Station
  
  6:30 AM
  
  Puerto Quijarro
  Bus Station
  
  0
  
  First Class
  
  $116
  
  A Bus from La Preferida Bus goes from Barra Funda Bus Station, São Paulo (Brazil) at 7/30/2026 1:00:00 PM to Bus Station, Puerto Quijarro (Bolivia) arriving at 7/31/2026 6:30:00 AM. 50 First Class ticket for $116 per person are available. Travel duration is 17h 30m
- Trans Quijarreno
  
  9h 30m
  
  0
  
  11:00 AM
  
  Puerto Quijarro
  Bus Station
  
  8:30 PM
  
  Santa Cruz de la Sierra
  Terminal Bimodal
  
  0
  
  First Class
  
  $14
  
  A Bus from Trans Quijarreno goes from Bus Station, Puerto Quijarro (Bolivia) at 8/1/2026 11:00:00 AM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 8/1/2026 8:30:00 PM. 50 First Class ticket for $14 per person are available. Travel duration is 9h 30m
Travel time is 17h 0m longer, but you will save $69

Test cheapest views

The cheapest bus for the 8/5/2026 costs just $137, from La Preferida Bus

Facts about the bus from São Paulo to Santa Cruz de la Sierra

Compare all providers like La Preferida Bus that travel 1 times every day by bus from São Paulo to Santa Cruz de la Sierra in one click! Book your bus ticket from São Paulo to Santa Cruz de la Sierra starting from $137!

Cheapest Bus	$137
Fastest Bus	38h 30m
Earliest Bus	1:00 PM
Latest Bus	1:00 PM
Daily Bus Routes	1 Ø
Distance	1,140.8 miles
Bus Companies	La Preferida Bus

Cheapest bus connections from São Paulo to Santa Cruz de la Sierra

Every day, 1 buses from 1 bus companies leave São Paulo for Santa Cruz de la Sierra: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

Monday 07/27

Tuesday 07/28

Wednesday 07/29

Thursday 07/30

Friday 07/31

Saturday 08/01

Sunday 08/02

Monday 08/03

Tuesday 08/04

Wednesday 08/05

$137

Thursday 08/06

Friday 08/07

Saturday 08/08

$144

Sunday 08/09

$144

Monday 08/10

Tuesday 08/11

$144

Wednesday 08/12

$199

Thursday 08/13

Friday 08/14

Saturday 08/15

Sunday 08/16

Monday 08/17

Tuesday 08/18

Wednesday 08/19

Thursday 08/20

Friday 08/21

Saturday 08/22

How to save money travelling from São Paulo to Santa Cruz de la Sierra

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from São Paulo to Santa Cruz de la Sierra in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from São Paulo to Santa Cruz de la Sierra, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from São Paulo to Santa Cruz de la Sierra are also emptier.

All bus stations and stops in São Paulo and Santa Cruz de la Sierra

In the map below, you can see where to find all bus stations in São Paulo and Santa Cruz de la Sierra.

Tietê Bus Station

Vila Guilherme

Barra Funda Bus Station

Rua Aloysio Biondi, s/n Barra Funda

Jabaquara Bus Station

Avenida Engenheiro Armando de Arruda Pereira 2022

Sala VIP Bella Vita

Av. Ordem e Progresso 95

Shopping Feira da Madrugada Bus Stop

Rua São Caetano 812

Terminal Bimodal

Av Intermodal

Service and Comfort on the bus from São Paulo to Santa Cruz de la Sierra

Want to know which seat classes are available on the buses from São Paulo to Santa Cruz de la Sierra? Or which bus companies serve the route São Paulo to Santa Cruz de la Sierra? Below you will find answers to your questions.

FAQs about the São Paulo to Santa Cruz de la Sierra bus

How much does a São Paulo Santa Cruz de la Sierra bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $137 and takes 38h 30m to reach Santa Cruz de la Sierra. Compare offers to save money!

How much could I save by comparing buses from São Paulo to Santa Cruz de la Sierra?

This route is offered by 1 companies with a range of ticket prices between $137 and $199. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Cruz de la Sierra.

On average, how many connections are available from São Paulo to Santa Cruz de la Sierra each day?

Every day, the São Paulo to Santa Cruz de la Sierra bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from São Paulo to Santa Cruz de la Sierra take?

The fastest bus from São Paulo to Santa Cruz de la Sierra is offered by La Preferida Bus and takes 38h 30m. Bus tickets for this connection cost $199. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from São Paulo to Santa Cruz de la Sierra?

The earliest bus arriving in Santa Cruz de la Sierra from São Paulo starts at 1:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from São Paulo to Santa Cruz de la Sierra?

The latest bus trip departing from São Paulo for Santa Cruz de la Sierra starts at 1:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the São Paulo Santa Cruz de la Sierra route?

When traveling by bus from São Paulo to Santa Cruz de la Sierra, passengers can travel with La Preferida Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between São Paulo and Santa Cruz de la Sierra?

You can check all the direct connections between São Paulo and Santa Cruz de la Sierra by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: La Preferida Bus.

What can I take with me on the São Paulo to Santa Cruz de la Sierra bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the São Paulo Santa Cruz de la Sierra bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the São Paulo Santa Cruz de la Sierra bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from São Paulo to Santa Cruz de la Sierra on your planned travel date.

Available seat classes which are offered on the bus route São Paulo to Santa Cruz de la Sierra

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to São Paulo and to Santa Cruz de la Sierra

Here’s an overview of the most popular bus routes to São Paulo and to Santa Cruz de la Sierra. Simply click on the connection of your choice, and you will find all the details about your bus route!