Bus Santiago del Estero to Buenos Aires: Compare prices and save money

Compare all timetables for the bus from Santiago del Estero to Buenos Aires

Here is a selection of the cheapest bus trips from the schedule from Santiago del Estero to Buenos Aires from various bus operators like Balut, 20 de Junio or Vosa for the next days.

today

$56

tomorrow

$46

Thursday

Friday

$54

Saturday

$48

Sunday

$54

Monday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Balut	14h 40m	4:45 PM	Santiago del Estero	Central Bus Station	7:25 AM	Buenos Aires	Liniers Bus Station	Premium Economy	$56	A Bus from Balut goes from Central Bus Station, Santiago del Estero (Argentina) at 9/8/2026 4:45:00 PM to Liniers Bus Station, Buenos Aires (Argentina) arriving at 9/9/2026 7:25:00 AM. 50 Premium Economy ticket for $56 per person are available. Travel duration is 14h 40m
Transporte La Union	17h 50m	12:30 PM	Santiago del Estero	Central Bus Station	6:20 AM	Buenos Aires	Liniers Bus Station	Premium Economy	$60	A Bus from Transporte La Union goes from Central Bus Station, Santiago del Estero (Argentina) at 9/8/2026 12:30:00 PM to Liniers Bus Station, Buenos Aires (Argentina) arriving at 9/9/2026 6:20:00 AM. 50 Premium Economy ticket for $60 per person are available. Travel duration is 17h 50m
20 de Junio	17h 10m	3:20 PM	Santiago del Estero	Central Bus Station	8:30 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$62	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 9/8/2026 3:20:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/9/2026 8:30:00 AM. 50 Premium Economy ticket for $62 per person are available. Travel duration is 17h 10m
La Veloz del Norte	16h 20m	5:25 PM	Santiago del Estero	Central Bus Station	9:45 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$64	A Bus from La Veloz del Norte goes from Central Bus Station, Santiago del Estero (Argentina) at 9/8/2026 5:25:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/9/2026 9:45:00 AM. 50 Premium Economy ticket for $64 per person are available. Travel duration is 16h 20m
Flecha Bus	15h 30m	8:10 PM	Santiago del Estero	Central Bus Station	11:40 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$75	A Bus from Flecha Bus goes from Central Bus Station, Santiago del Estero (Argentina) at 9/8/2026 8:10:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/9/2026 11:40:00 AM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 15h 30m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
La Veloz del Norte	16h 20m	1:20 AM	Santiago del Estero	Central Bus Station	5:40 PM	Buenos Aires	Retiro Bus Station	Premium Economy	$46	A Bus from La Veloz del Norte goes from Central Bus Station, Santiago del Estero (Argentina) at 9/9/2026 1:20:00 AM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/9/2026 5:40:00 PM. 50 Premium Economy ticket for $46 per person are available. Travel duration is 16h 20m
Vosa	15h 30m	7:40 PM	Santiago del Estero	Central Bus Station	11:10 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$48	A Bus from Vosa goes from Central Bus Station, Santiago del Estero (Argentina) at 9/9/2026 7:40:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/10/2026 11:10:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 15h 30m
Rutatlántica	15h 20m	5:00 PM	Santiago del Estero	Central Bus Station	8:20 AM	Buenos Aires	Julio A. Roca Bus Stop	Premium Economy	$48	A Bus from Rutatlántica goes from Central Bus Station, Santiago del Estero (Argentina) at 9/9/2026 5:00:00 PM to Julio A. Roca Bus Stop, Buenos Aires (Argentina) arriving at 9/10/2026 8:20:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 15h 20m
20 de Junio	16h 45m	1:15 AM	Santiago del Estero	Central Bus Station	6:00 PM	Buenos Aires	Retiro Bus Station	Premium Economy	$56	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 9/9/2026 1:15:00 AM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/9/2026 6:00:00 PM. 50 Premium Economy ticket for $56 per person are available. Travel duration is 16h 45m
Balut	15h 0m	1:40 AM	Santiago del Estero	Central Bus Station	4:40 PM	Buenos Aires	Retiro Bus Station	Premium Economy	$56	A Bus from Balut goes from Central Bus Station, Santiago del Estero (Argentina) at 9/9/2026 1:40:00 AM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/9/2026 4:40:00 PM. 50 Premium Economy ticket for $56 per person are available. Travel duration is 15h 0m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
La Veloz del Norte	16h 20m	5:25 PM	Santiago del Estero	Central Bus Station	9:45 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$54	A Bus from La Veloz del Norte goes from Central Bus Station, Santiago del Estero (Argentina) at 9/11/2026 5:25:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/12/2026 9:45:00 AM. 50 Premium Economy ticket for $54 per person are available. Travel duration is 16h 20m
Balut	15h 0m	1:40 AM	Santiago del Estero	Central Bus Station	4:40 PM	Buenos Aires	Retiro Bus Station	Premium Economy	$56	A Bus from Balut goes from Central Bus Station, Santiago del Estero (Argentina) at 9/11/2026 1:40:00 AM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/11/2026 4:40:00 PM. 50 Premium Economy ticket for $56 per person are available. Travel duration is 15h 0m
20 de Junio	16h 45m	1:15 AM	Santiago del Estero	Central Bus Station	6:00 PM	Buenos Aires	Retiro Bus Station	Premium Economy	$59	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 9/11/2026 1:15:00 AM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/11/2026 6:00:00 PM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 16h 45m
Transporte La Union	18h 0m	12:30 PM	Santiago del Estero	Central Bus Station	6:30 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$60	A Bus from Transporte La Union goes from Central Bus Station, Santiago del Estero (Argentina) at 9/11/2026 12:30:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/12/2026 6:30:00 AM. 50 Premium Economy ticket for $60 per person are available. Travel duration is 18h 0m
Flecha Bus	16h 5m	5:50 PM	Santiago del Estero	Central Bus Station	9:55 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$75	A Bus from Flecha Bus goes from Central Bus Station, Santiago del Estero (Argentina) at 9/11/2026 5:50:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/12/2026 9:55:00 AM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 16h 5m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flecha Bus	15h 30m	8:10 PM	Santiago del Estero	Central Bus Station	11:40 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$48	A Bus from Flecha Bus goes from Central Bus Station, Santiago del Estero (Argentina) at 9/12/2026 8:10:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/13/2026 11:40:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 15h 30m
Balut	15h 0m	1:40 AM	Santiago del Estero	Central Bus Station	4:40 PM	Buenos Aires	Retiro Bus Station	Premium Economy	$56	A Bus from Balut goes from Central Bus Station, Santiago del Estero (Argentina) at 9/12/2026 1:40:00 AM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/12/2026 4:40:00 PM. 50 Premium Economy ticket for $56 per person are available. Travel duration is 15h 0m
La Veloz del Norte	16h 20m	5:25 PM	Santiago del Estero	Central Bus Station	9:45 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$60	A Bus from La Veloz del Norte goes from Central Bus Station, Santiago del Estero (Argentina) at 9/12/2026 5:25:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/13/2026 9:45:00 AM. 50 Premium Economy ticket for $60 per person are available. Travel duration is 16h 20m
Transporte La Union	18h 0m	12:30 PM	Santiago del Estero	Central Bus Station	6:30 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$60	A Bus from Transporte La Union goes from Central Bus Station, Santiago del Estero (Argentina) at 9/12/2026 12:30:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/13/2026 6:30:00 AM. 50 Premium Economy ticket for $60 per person are available. Travel duration is 18h 0m
Vosa	13h 30m	7:50 PM	Santiago del Estero	Central Bus Station	9:20 AM	Buenos Aires	Julio A. Roca Bus Stop	Premium Economy	$60	A Bus from Vosa goes from Central Bus Station, Santiago del Estero (Argentina) at 9/12/2026 7:50:00 PM to Julio A. Roca Bus Stop, Buenos Aires (Argentina) arriving at 9/13/2026 9:20:00 AM. 50 Premium Economy ticket for $60 per person are available. Travel duration is 13h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
La Veloz del Norte	16h 20m	5:25 PM	Santiago del Estero	Central Bus Station	9:45 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$54	A Bus from La Veloz del Norte goes from Central Bus Station, Santiago del Estero (Argentina) at 9/13/2026 5:25:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/14/2026 9:45:00 AM. 50 Premium Economy ticket for $54 per person are available. Travel duration is 16h 20m
Balut	15h 0m	1:40 AM	Santiago del Estero	Central Bus Station	4:40 PM	Buenos Aires	Retiro Bus Station	Premium Economy	$56	A Bus from Balut goes from Central Bus Station, Santiago del Estero (Argentina) at 9/13/2026 1:40:00 AM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/13/2026 4:40:00 PM. 50 Premium Economy ticket for $56 per person are available. Travel duration is 15h 0m
20 de Junio	16h 45m	1:15 AM	Santiago del Estero	Central Bus Station	6:00 PM	Buenos Aires	Retiro Bus Station	Premium Economy	$59	A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 9/13/2026 1:15:00 AM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/13/2026 6:00:00 PM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 16h 45m
Transporte La Union	18h 0m	12:30 PM	Santiago del Estero	Central Bus Station	6:30 AM	Buenos Aires	Retiro Bus Station	Premium Economy	$60	A Bus from Transporte La Union goes from Central Bus Station, Santiago del Estero (Argentina) at 9/13/2026 12:30:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/14/2026 6:30:00 AM. 50 Premium Economy ticket for $60 per person are available. Travel duration is 18h 0m
Flecha Bus	15h 50m	12:30 AM	Santiago del Estero	Central Bus Station	4:20 PM	Buenos Aires	Retiro Bus Station	Premium Economy	$75	A Bus from Flecha Bus goes from Central Bus Station, Santiago del Estero (Argentina) at 9/13/2026 12:30:00 AM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/13/2026 4:20:00 PM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 15h 50m

Did you know that if you travel from Santiago del Estero to Buenos Aires via Rosario, SF, you can save more than $5? You can find the corresponding connections below.
- 20 de Junio
  
  18h 10m
  
  0
  
  5:20 AM
  
  Santiago del Estero
  Central Bus Station
  
  5:30 PM
  
  Rosario, SF
  Bus Station
  
  0
  
  Premium Economy
  
  $35
  
  A Bus from 20 de Junio goes from Central Bus Station, Santiago del Estero (Argentina) at 9/13/2026 5:20:00 AM to Bus Station, Rosario, SF (Argentina) arriving at 9/13/2026 5:30:00 PM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 12h 10m
- El Rosarino
  
  4h 30m
  
  0
  
  7:00 PM
  
  Rosario, SF
  Bus Station
  
  11:30 PM
  
  Buenos Aires
  Retiro Bus Station
  
  0
  
  Premium Economy
  
  $13
  
  A Bus from El Rosarino goes from Bus Station, Rosario, SF (Argentina) at 9/13/2026 7:00:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 9/13/2026 11:30:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 30m
Travel time is 3h 10m longer, but you will save $5

Frequency of bus connections between Santiago del Estero and Buenos Aires

See here how frequent the connections between Santiago del Estero and Buenos Aires are, during different times and days of the week.

Sunday is the busiest day, with more than 69 daily buses from Santiago del Estero to Buenos Aires. Tuesday has instead the fewest connections, with only 31 daily coaches between Santiago del Estero and Buenos Aires.

The busiest time of the day is the Night, with 136 buses from Santiago del Estero to Buenos Aires, while Evening sees the fewest connections between Santiago del Estero and Buenos Aires, with 33 offers.

Test cheapest views

The cheapest bus for the 9/7/2026 costs just $38, from La Veloz del Norte

Facts about the bus from Santiago del Estero to Buenos Aires

Compare all providers like Balut, 20 de Junio and Vosa that travel 57 times every day by bus from Santiago del Estero to Buenos Aires in one click! Book your bus ticket from Santiago del Estero to Buenos Aires starting from $38!

Cheapest Bus	$38
Fastest Bus	12h 20m
Earliest Bus	12:30 PM
Latest Bus	11:45 PM
Daily Bus Routes	57 Ø
Distance	586.1 miles
Bus Companies	Balut, 20 de Junio, Vosa, La Veloz del Norte, Flecha Bus, Rutatlántica and Transporte La Union

Cheapest bus connections from Santiago del Estero to Buenos Aires

Every day, 57 buses from 7 bus companies leave Santiago del Estero for Buenos Aires: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/08/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

$46

Wednesday 09/09

$46

Thursday 09/10

$53

Friday 09/11

$75

Saturday 09/12

$48

Sunday 09/13

$46

Monday 09/14

$56

Tuesday 09/15

$46

Wednesday 09/16

Thursday 09/17

$56

Friday 09/18

$53

Saturday 09/19

Sunday 09/20

$53

Monday 09/21

$75

Tuesday 09/22

Wednesday 09/23

Thursday 09/24

Friday 09/25

$46

Saturday 09/26

Sunday 09/27

Monday 09/28

$53

Tuesday 09/29

$53

Wednesday 09/30

Thursday 10/01

$48

Friday 10/02

Saturday 10/03

The cheapest time to travel from Santiago del Estero to Buenos Aires

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago del Estero to Buenos Aires, for the next 30 days.

With a price starting from $46, Wednesday is the cheapest day for a bus from Santiago del Estero to Buenos Aires. Saturday instead is the most expensive day with prices starting from $48.

Afternoon is the cheapest day time for bus tickets from Santiago del Estero to Buenos Aires, with $46. Evening is the most expensive time of the day with prices starting from $48.

How to save money travelling from Santiago del Estero to Buenos Aires

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago del Estero to Buenos Aires in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago del Estero to Buenos Aires, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago del Estero to Buenos Aires are also emptier.

Latest reviews for bus companies on the route Santiago del Estero - Buenos Aires

Nicole, 10/14/2025

Impuntuales totalmente siempre! Porque no es la primera vez y lo comentamos entre varios pasajeros. Teníamos que llegar 8.20 am a retiro, son las 10.30 am seguimos por liniers, cuando primero tenía qu ... Impuntuales totalmente siempre! Porque no es la primera vez y lo comentamos entre varios pasajeros. Teníamos que llegar 8.20 am a retiro, son las 10.30 am seguimos por liniers, cuando primero tenía que pasar por retiro según el recorrido online. Por ende van más de dos horas de demora en la hora de llegada. Tenemos turnos medicos y juegan con la salud y tiempo de la gente. Sumamente impuntuales llegó tarde a buscarnos llega tarde a dejarnos

All bus stations and stops in Santiago del Estero and Buenos Aires

In the map below, you can see where to find all bus stations in Santiago del Estero and Buenos Aires.

Central Bus Station

Av. Roca Norte 100

Av. Libertad & Av. Aguirre

Ambargasta

Bus Stop

RN9

El Saladillo

Liniers Bus Station

Avenida General Paz , Liniers 10868/76

Retiro Bus Station

Av. Antártida Argentina y Calle 10 - Capital Federal. 10

Terminal de Ómnibus Dellepiane

Teniente General Luís Dellepiane Av. Perito Moreno 3950, Villa Soldati, Ciudad de Buenos Aires

Villa Tesei

Reyes Catolicos 246

Thames - Panamericana

Service and Comfort on the bus from Santiago del Estero to Buenos Aires

Want to know which seat classes are available on the buses from Santiago del Estero to Buenos Aires? Or which bus companies serve the route Santiago del Estero to Buenos Aires? Below you will find answers to your questions.

FAQs about the Santiago del Estero to Buenos Aires bus

How much does a Santiago del Estero Buenos Aires bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $38 and takes 16h 20m to reach Buenos Aires. Compare offers to save money!

How much could I save by comparing buses from Santiago del Estero to Buenos Aires?

This route is offered by 7 companies with a range of ticket prices between $38 and $106. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Buenos Aires.

On average, how many connections are available from Santiago del Estero to Buenos Aires each day?

Every day, the Santiago del Estero to Buenos Aires bus route is served by approximately 57 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago del Estero to Buenos Aires take?

The fastest bus from Santiago del Estero to Buenos Aires is offered by Vosa and takes 12h 20m. Bus tickets for this connection cost $65. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago del Estero to Buenos Aires?

The earliest bus arriving in Buenos Aires from Santiago del Estero starts at 12:30 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago del Estero to Buenos Aires?

The latest bus trip departing from Santiago del Estero for Buenos Aires starts at 11:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago del Estero Buenos Aires route?

When traveling by bus from Santiago del Estero to Buenos Aires, passengers can travel with Balut, 20 de Junio and Vosa. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago del Estero and Buenos Aires?

You can check all the direct connections between Santiago del Estero and Buenos Aires by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Balut, 20 de Junio and Vosa.

What can I take with me on the Santiago del Estero to Buenos Aires bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago del Estero Buenos Aires bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago del Estero Buenos Aires bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago del Estero to Buenos Aires on your planned travel date.

Available seat classes which are offered on the bus route Santiago del Estero to Buenos Aires

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Santiago del Estero and to Buenos Aires

Here’s an overview of the most popular bus routes to Santiago del Estero and to Buenos Aires. Simply click on the connection of your choice, and you will find all the details about your bus route!