Bus San Luis Potosí to Mezcales: Compare prices and save money

Compare all timetables for the bus from San Luis Potosí to Mezcales

Here is a selection of the cheapest bus trips from the schedule from San Luis Potosí to Mezcales from various bus operators like ETN Autobuses for the next days.

today

$155

tomorrow

Wednesday

$155

Thursday

Friday

$155

Saturday

Sunday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ETN Autobuses	10h 11m	11:59 PM	San Luis Potosí	Central Bus Station	10:10 AM	Mezcales	Vallarte Plus		Premium Economy	$155	A Bus from ETN Autobuses goes from Central Bus Station, San Luis Potosí (Mexico) at 7/27/2026 11:59:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 7/28/2026 10:10:00 AM. 50 Premium Economy ticket for $155 per person are available. Travel duration is 10h 11m

Did you know that if you travel from San Luis Potosí to Mezcales via Guadalajara, JC, you can save more than $55? You can find the corresponding connections below.
- Primera Plus
  
  10h 21m
  
  0
  
  4:50 PM
  
  San Luis Potosí
  Central Bus Station
  
  9:50 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  0
  
  Economy
  
  $54
  
  A Bus from Primera Plus goes from Central Bus Station, San Luis Potosí (Mexico) at 7/28/2026 4:50:00 PM to Central de Autobuses, Guadalajara, JC (Mexico) arriving at 7/28/2026 9:50:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 5h 0m
- Pacífico
  
  5h 11m
  
  0
  
  10:00 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  3:11 AM
  
  Mezcales
  Primera Plus
  
  0
  
  Economy
  
  $46
  
  A Bus from Pacífico goes from Central de Autobuses, Guadalajara, JC (Mexico) at 7/28/2026 10:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 7/29/2026 3:11:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 11m
Travel time is 0h 10m longer, but you will save $55

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ETN Autobuses	10h 11m	11:59 PM	San Luis Potosí	Central Bus Station	10:10 AM	Mezcales	Vallarte Plus		Premium Economy	$155	A Bus from ETN Autobuses goes from Central Bus Station, San Luis Potosí (Mexico) at 7/29/2026 11:59:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 7/30/2026 10:10:00 AM. 50 Premium Economy ticket for $155 per person are available. Travel duration is 10h 11m

Did you know that if you travel from San Luis Potosí to Mezcales via Guadalajara, JC, you can save more than $95? You can find the corresponding connections below.
- Ómnibus de Oriente
  
  7h 22m
  
  0
  
  7:30 AM
  
  San Luis Potosí
  Central Bus Station
  
  9:53 AM
  
  Guadalajara, JC
  18 De Marzo Bus Stop
  
  0
  
  Economy
  
  $14
  
  A Bus from Ómnibus de Oriente goes from Central Bus Station, San Luis Potosí (Mexico) at 7/31/2026 7:30:00 AM to 18 De Marzo Bus Stop, Guadalajara, JC (Mexico) arriving at 7/31/2026 9:53:00 AM. 50 Economy ticket for $14 per person are available. Travel duration is 2h 23m
- Pacífico
  
  4h 52m
  
  0
  
  10:00 AM
  
  Guadalajara, JC
  Central de Autobuses
  
  2:52 PM
  
  Mezcales
  Primera Plus
  
  0
  
  Economy
  
  $46
  
  A Bus from Pacífico goes from Central de Autobuses, Guadalajara, JC (Mexico) at 7/31/2026 10:00:00 AM to Primera Plus, Mezcales (Mexico) arriving at 7/31/2026 2:52:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 4h 52m
Travel Time is 2h 49m shorter, and you will save $95

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ETN Autobuses	10h 11m	11:59 PM	San Luis Potosí	Central Bus Station	10:10 AM	Mezcales	Vallarte Plus		Premium Economy	$155	A Bus from ETN Autobuses goes from Central Bus Station, San Luis Potosí (Mexico) at 7/31/2026 11:59:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 8/1/2026 10:10:00 AM. 50 Premium Economy ticket for $155 per person are available. Travel duration is 10h 11m

Did you know that if you travel from San Luis Potosí to Mezcales via Guadalajara, JC, you can save more than $95? You can find the corresponding connections below.
- Ómnibus de Oriente
  
  7h 22m
  
  0
  
  7:30 AM
  
  San Luis Potosí
  Central Bus Station
  
  9:53 AM
  
  Guadalajara, JC
  18 De Marzo Bus Stop
  
  0
  
  Economy
  
  $14
  
  A Bus from Ómnibus de Oriente goes from Central Bus Station, San Luis Potosí (Mexico) at 7/31/2026 7:30:00 AM to 18 De Marzo Bus Stop, Guadalajara, JC (Mexico) arriving at 7/31/2026 9:53:00 AM. 50 Economy ticket for $14 per person are available. Travel duration is 2h 23m
- Pacífico
  
  4h 52m
  
  0
  
  10:00 AM
  
  Guadalajara, JC
  Central de Autobuses
  
  2:52 PM
  
  Mezcales
  Primera Plus
  
  0
  
  Economy
  
  $46
  
  A Bus from Pacífico goes from Central de Autobuses, Guadalajara, JC (Mexico) at 7/31/2026 10:00:00 AM to Primera Plus, Mezcales (Mexico) arriving at 7/31/2026 2:52:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 4h 52m
Travel Time is 2h 49m shorter, and you will save $95

Test cheapest views

The cheapest bus for the 8/9/2026 costs just $110, from ETN Autobuses

Facts about the bus from San Luis Potosí to Mezcales

Compare all providers like ETN Autobuses that travel 1 times every day by bus from San Luis Potosí to Mezcales in one click! Book your bus ticket from San Luis Potosí to Mezcales starting from $110!

Cheapest Bus	$110
Fastest Bus	10h 11m
Earliest Bus	11:59 PM
Latest Bus	11:59 PM
Daily Bus Routes	1 Ø
Distance	295.3 miles
Bus Companies	ETN Autobuses

Cheapest bus connections from San Luis Potosí to Mezcales

Every day, 1 buses from 1 bus companies leave San Luis Potosí for Mezcales: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

Monday 07/27

$155

Tuesday 07/28

Wednesday 07/29

$155

Thursday 07/30

Friday 07/31

$155

Saturday 08/01

$155

Sunday 08/02

Monday 08/03

Tuesday 08/04

$156

Wednesday 08/05

Thursday 08/06

$156

Friday 08/07

Saturday 08/08

$156

Sunday 08/09

$110

Monday 08/10

$156

Tuesday 08/11

$156

Wednesday 08/12

$154

Thursday 08/13

Friday 08/14

Saturday 08/15

Sunday 08/16

Monday 08/17

Tuesday 08/18

Wednesday 08/19

Thursday 08/20

Friday 08/21

Saturday 08/22

How to save money travelling from San Luis Potosí to Mezcales

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Luis Potosí to Mezcales in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Luis Potosí to Mezcales, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Luis Potosí to Mezcales are also emptier.

All bus stations and stops in San Luis Potosí and Mezcales

In the map below, you can see where to find all bus stations in San Luis Potosí and Mezcales.

Central Bus Station

Av Benito Juarez 250

Soriana El Paseo Bus Station

Doctor Salvador Nava Martínez 405

Av Constitución / Manual José Othón Bus Stop

Avenida Constitución 300

Barrio de Santiago

Bus Stop

Primera Plus

Blvrd Riviera Nayarit 171

Service and Comfort on the bus from San Luis Potosí to Mezcales

Want to know which seat classes are available on the buses from San Luis Potosí to Mezcales? Or which bus companies serve the route San Luis Potosí to Mezcales? Below you will find answers to your questions.

FAQs about the San Luis Potosí to Mezcales bus

How much does a San Luis Potosí Mezcales bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $110 and takes 10h 11m to reach Mezcales. Compare offers to save money!

How much could I save by comparing buses from San Luis Potosí to Mezcales?

This route is offered by 1 companies with a range of ticket prices between $110 and $155. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mezcales.

On average, how many connections are available from San Luis Potosí to Mezcales each day?

Every day, the San Luis Potosí to Mezcales bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Luis Potosí to Mezcales take?

The fastest bus from San Luis Potosí to Mezcales is offered by ETN Autobuses and takes 10h 11m. Bus tickets for this connection cost $155. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Luis Potosí to Mezcales?

The earliest bus arriving in Mezcales from San Luis Potosí starts at 11:59 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Luis Potosí to Mezcales?

The latest bus trip departing from San Luis Potosí for Mezcales starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Luis Potosí Mezcales route?

When traveling by bus from San Luis Potosí to Mezcales, passengers can travel with ETN Autobuses. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Luis Potosí and Mezcales?

You can check all the direct connections between San Luis Potosí and Mezcales by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ETN Autobuses.

What can I take with me on the San Luis Potosí to Mezcales bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Luis Potosí Mezcales bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Luis Potosí Mezcales bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Luis Potosí to Mezcales on your planned travel date.

Available seat classes which are offered on the bus route San Luis Potosí to Mezcales

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to San Luis Potosí and to Mezcales

Here’s an overview of the most popular bus routes to San Luis Potosí and to Mezcales. Simply click on the connection of your choice, and you will find all the details about your bus route!