Compare all timetables for the bus from Prague to Rome
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 20h 25m | 9:25 PM | Prague | ÚAN Florenc | 5:50 PM | Rome | Anagnina Bus Station | Economy | $91 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/7/2026 9:25:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 9/8/2026 5:50:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 20h 25m
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| FlixBus | 25h 10m | 9:50 PM | Prague | Na Knížecí Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $92 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 9/7/2026 9:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/8/2026 11:00:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 25h 10m
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| FlixBus | 20h 0m | 9:25 PM | Prague | ÚAN Florenc | 5:25 PM | Rome | Tiburtina Bus Station | Economy | $93 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/7/2026 9:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/8/2026 5:25:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 20h 0m
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| FlixBus | 23h 20m | 11:40 PM | Prague | ÚAN Florenc | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $93 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/7/2026 11:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/8/2026 11:00:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 20m
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| FlixBus | 24h 35m | 10:25 PM | Prague | Hradčanská | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $93 |
A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 9/7/2026 10:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/8/2026 11:00:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 24h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 20h 0m | 9:25 PM | Prague | ÚAN Florenc | 5:25 PM | Rome | Tiburtina Bus Station | Economy | $86 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/8/2026 9:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/9/2026 5:25:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 20h 0m
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| FlixBus | 23h 20m | 11:40 PM | Prague | ÚAN Florenc | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $87 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/8/2026 11:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/9/2026 11:00:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 23h 20m
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| FlixBus | 23h 50m | 9:40 AM | Prague | Na Knížecí Station | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $87 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 9/8/2026 9:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/9/2026 9:30:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 23h 50m
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| FlixBus | 26h 35m | 9:40 AM | Prague | Na Knížecí Station | 12:15 PM | Rome | Anagnina Bus Station | Economy | $87 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 9/8/2026 9:40:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 9/9/2026 12:15:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 26h 35m
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| FlixBus | 27h 40m | 5:50 AM | Prague | Wilsonova Bus Station | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $88 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/8/2026 5:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/9/2026 9:30:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 27h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 20m | 11:40 PM | Prague | ÚAN Florenc | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $83 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/9/2026 11:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/10/2026 11:00:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 23h 20m
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| FlixBus | 25h 10m | 9:50 PM | Prague | Na Knížecí Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $83 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 9/9/2026 9:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/10/2026 11:00:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 25h 10m
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| FlixBus | 20h 30m | 2:30 AM | Prague | Wilsonova Bus Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $84 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/9/2026 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/9/2026 11:00:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 20h 30m
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| FlixBus | 23h 15m | 10:05 AM | Prague | Wilsonova Bus Station | 9:20 AM | Rome | Tiburtina Bus Station | Economy | $84 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/9/2026 10:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/10/2026 9:20:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 23h 15m
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| FlixBus | 20h 25m | 1:05 PM | Prague | Wilsonova Bus Station | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $84 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/9/2026 1:05:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/10/2026 9:30:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 20h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 25h 10m | 9:50 PM | Prague | Na Knížecí Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $85 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 9/10/2026 9:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/11/2026 11:00:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 25h 10m
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| FlixBus | 20h 30m | 2:30 AM | Prague | Wilsonova Bus Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $86 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/10/2026 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/10/2026 11:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 20h 30m
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| FlixBus | 27h 40m | 5:50 AM | Prague | Wilsonova Bus Station | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $86 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/10/2026 5:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/11/2026 9:30:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 27h 40m
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| FlixBus | 23h 50m | 9:40 AM | Prague | Na Knížecí Station | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $86 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 9/10/2026 9:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/11/2026 9:30:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 23h 50m
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| FlixBus | 25h 0m | 8:30 AM | Prague | Roztyly | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $86 |
A Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 9/10/2026 8:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/11/2026 9:30:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 25h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 20h 30m | 2:30 AM | Prague | Wilsonova Bus Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $94 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/11/2026 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/11/2026 11:00:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 20h 30m
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| FlixBus | 23h 50m | 6:55 PM | Prague | Zličín | 6:45 PM | Rome | Tiburtina Bus Station | Economy | $98 |
A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 9/11/2026 6:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/12/2026 6:45:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 23h 50m
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| FlixBus | 23h 50m | 9:40 AM | Prague | Na Knížecí Station | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $101 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 9/11/2026 9:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/12/2026 9:30:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 23h 50m
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| FlixBus | 25h 10m | 9:50 PM | Prague | Na Knížecí Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $102 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 9/11/2026 9:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/12/2026 11:00:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 25h 10m
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| FlixBus | 24h 35m | 10:25 PM | Prague | Hradčanská | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $103 |
A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 9/11/2026 10:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/12/2026 11:00:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 24h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 20h 15m | 4:00 PM | Prague | ÚAN Florenc | 12:15 PM | Rome | Anagnina Bus Station | Economy | $105 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/12/2026 4:00:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 9/13/2026 12:15:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 20h 15m
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| FlixBus | 20h 0m | 4:15 PM | Prague | Wilsonova Bus Station | 12:15 PM | Rome | Anagnina Bus Station | Economy | $105 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 9/12/2026 4:15:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 9/13/2026 12:15:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 20h 0m
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| FlixBus | 25h 0m | 8:30 AM | Prague | Roztyly | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $107 |
A Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 9/12/2026 8:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/13/2026 9:30:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 25h 0m
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| FlixBus | 23h 50m | 6:20 AM | Prague | Černý Most | 6:10 AM | Rome | Tiburtina Bus Station | Economy | $108 |
A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 9/12/2026 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/13/2026 6:10:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 23h 50m
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| FlixBus | 23h 10m | 7:00 AM | Prague | ÚAN Florenc | 6:10 AM | Rome | Tiburtina Bus Station | Economy | $108 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/12/2026 7:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 9/13/2026 6:10:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 23h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 25h 10m | 9:50 PM | Prague | Na Knížecí Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $105 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 9/13/2026 9:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/14/2026 11:00:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 25h 10m
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| FlixBus | 22h 20m | 8:25 PM | Prague | Zličín | 6:45 PM | Rome | Tiburtina Bus Station | Economy | $105 |
A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 9/13/2026 8:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/14/2026 6:45:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 22h 20m
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| FlixBus | 23h 20m | 11:40 PM | Prague | ÚAN Florenc | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $106 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/13/2026 11:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/14/2026 11:00:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 23h 20m
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| FlixBus | 24h 35m | 10:25 PM | Prague | Hradčanská | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $106 |
A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 9/13/2026 10:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 9/14/2026 11:00:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 24h 35m
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| FlixBus | 20h 15m | 4:00 PM | Prague | ÚAN Florenc | 12:15 PM | Rome | Anagnina Bus Station | Economy | $107 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 9/13/2026 4:00:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 9/14/2026 12:15:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 20h 15m
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Best Price Offer: The price for the cheapest bus from Prague to Rome is $66 on 9/21/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Prague and Rome
Facts about the bus from Prague to Rome
Compare all providers like FlixBus that travel 33 times every day by bus from Prague to Rome in one click! Book your bus ticket from Prague to Rome starting from $66!
| Cheapest Bus | $66 |
| Fastest Bus | 19h 15m |
| Earliest Bus | 5:45 PM |
| Latest Bus | 11:50 PM |
| Daily Bus Routes | 33 Ø |
| Distance | 572.5 miles |
| Bus Companies | FlixBus |
Cheapest bus connections from Prague to Rome
Every day, 33 buses from 1 bus companies leave Prague for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/07/2026 and for the following days.
The cheapest time to travel from Prague to Rome
How to save money travelling from Prague to Rome
Book the ticket from Prague to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Rome, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Rome are also emptier.All bus stations and stops in Prague and Rome
In the map below, you can see where to find all bus stations in Prague and Rome.
Service and Comfort on the bus from Prague to Rome
FAQs about the Prague to Rome bus
How much does a Prague Rome bus trip cost?
How much could I save by comparing buses from Prague to Rome?
On average, how many connections are available from Prague to Rome each day?
How long does a bus journey from Prague to Rome take?
What time is the first bus from Prague to Rome?
What time is the last bus from Prague to Rome?
Which bus companies operate the Prague Rome route?
Is there a direct bus between Prague and Rome?
What can I take with me on the Prague to Rome bus route?
What equipment is available for the Prague Rome bus route?
Available seat classes which are offered on the bus route Prague to Rome
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Prague and to Rome
- Bus Routes to Prague
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- Hamburg to Prague bus
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- Bus to Prague from Moscow
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- Bus Poznan - Prague
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- Bus Routes to Rome
- Amsterdam to Rome bus
- Buses Barcelona - Rome
- Bus Bari to Rome
- Bus Barletta to Rome
- Bus Bologna to Rome
- Buses to Rome from Brussels
- From Catania to Rome bus
- Florence to Rome bus
- Bus Gdańsk to Rome
- Bus from La Spezia to Rome
- From Lviv to Rome bus
- Buses Marseille - Rome
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- Buses to Rome from Munich
- Bus Naples - Rome
- Buses Nice to Rome
- Bus to Rome from Turin
- Bus Winterthur - Rome
- Buses Zagreb to Rome
- Buses Zurich to Rome
