Bus from Port Saint Lucie, FL to Lafayette, LA from $104

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Compare all timetables for the bus from Port Saint Lucie, FL to Lafayette, LA

Here is a selection of the cheapest bus trips from the schedule from Port Saint Lucie, FL to Lafayette, LA from various bus operators like FlixBus or Greyhound US for the next days.
today
$104
tomorrow
$104
Wednesday
Thursday
Friday
Saturday
Sunday
$104

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 23h 10m 8:45 AM Port Saint Lucie, FL RaceTrac Gas Station 6:55 AM Lafayette, LA Bus Stop  Economy $104
Greyhound US 31h 20m 8:45 AM Port Saint Lucie, FL RaceTrac Gas Station 3:05 PM Lafayette, LA TA Travel Center  Economy $131
FlixBus 28h 5m 6:10 PM Port Saint Lucie, FL RaceTrac Gas Station 9:15 PM Lafayette, LA Bus Stop  Economy $163
FlixBus 32h 15m 6:10 PM Port Saint Lucie, FL RaceTrac Gas Station 1:25 AM Lafayette, LA TA Travel Center  Economy $164

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 23h 10m 8:45 AM Port Saint Lucie, FL RaceTrac Gas Station 6:55 AM Lafayette, LA Bus Stop  Economy $104
Greyhound US 33h 25m 8:45 AM Port Saint Lucie, FL RaceTrac Gas Station 5:10 PM Lafayette, LA TA Travel Center  Economy $105
FlixBus 24h 45m 1:40 AM Port Saint Lucie, FL RaceTrac Gas Station 1:25 AM Lafayette, LA TA Travel Center  Economy $110
FlixBus 28h 5m 6:10 PM Port Saint Lucie, FL RaceTrac Gas Station 9:15 PM Lafayette, LA Bus Stop  Economy $138
FlixBus 26h 25m 1:40 AM Port Saint Lucie, FL RaceTrac Gas Station 3:05 AM Lafayette, LA Bus Stop  Economy $165

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 26h 20m 8:45 AM Port Saint Lucie, FL RaceTrac Gas Station 10:05 AM Lafayette, LA TA Travel Center  Economy $104
Greyhound US 23h 10m 8:45 AM Port Saint Lucie, FL RaceTrac Gas Station 6:55 AM Lafayette, LA Bus Stop  Economy $104
FlixBus 24h 45m 1:40 AM Port Saint Lucie, FL RaceTrac Gas Station 1:25 AM Lafayette, LA TA Travel Center  Economy $110
FlixBus 32h 15m 6:10 PM Port Saint Lucie, FL RaceTrac Gas Station 1:25 AM Lafayette, LA TA Travel Center  Economy $133
FlixBus 28h 5m 6:10 PM Port Saint Lucie, FL RaceTrac Gas Station 9:15 PM Lafayette, LA Bus Stop  Economy $134

Frequency of bus connections between Port Saint Lucie, FL and Lafayette, LA

See here how frequent the connections between Port Saint Lucie, FL and Lafayette, LA are, during different times and days of the week.
Sunday is the busiest day, with more than 6 daily buses from Port Saint Lucie, FL to Lafayette, LA. Monday has instead the fewest connections, with only 4 daily coaches between Port Saint Lucie, FL and Lafayette, LA.
The busiest time of the day is the Morning, with 6 buses from Port Saint Lucie, FL to Lafayette, LA, while Night sees the fewest connections between Port Saint Lucie, FL and Lafayette, LA, with 4 offers.

Test cheapest views

The cheapest bus for the 8/2/2026 costs just $104, from Greyhound US

Facts about the bus from Port Saint Lucie, FL to Lafayette, LA

Compare all providers like FlixBus and Greyhound US that travel 5 times every day by bus from Port Saint Lucie, FL to Lafayette, LA in one click! Book your bus ticket from Port Saint Lucie, FL to Lafayette, LA starting from $104!

Cheapest Bus $104
Fastest Bus 22h 10m
Earliest Bus 8:45 AM
Latest Bus 6:10 PM
Daily Bus Routes 5 Ø
Distance 735.1 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Port Saint Lucie, FL to Lafayette, LA

Every day, 5 buses from 2 bus companies leave Port Saint Lucie, FL for Lafayette, LA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/26
Monday 07/27
$104
Tuesday 07/28
$104
Wednesday 07/29
Thursday 07/30
Friday 07/31
Saturday 08/01
Sunday 08/02
$104
Monday 08/03
Tuesday 08/04
$104
Wednesday 08/05
Thursday 08/06
Friday 08/07
$104
Saturday 08/08
Sunday 08/09
$104
Monday 08/10
Tuesday 08/11
Wednesday 08/12
Thursday 08/13
Friday 08/14
Saturday 08/15
Sunday 08/16
$104
Monday 08/17
Tuesday 08/18
$104
Wednesday 08/19
Thursday 08/20
Friday 08/21
Saturday 08/22

The cheapest time to travel from Port Saint Lucie, FL to Lafayette, LA

See here on which day and which time of the day you can find the cheapest bus ticket from Port Saint Lucie, FL to Lafayette, LA, for the next 30 days.
With a price starting from $104, Sunday is the cheapest day for a bus from Port Saint Lucie, FL to Lafayette, LA. Monday instead is the most expensive day with prices starting from $104.
Morning is the cheapest day time for bus tickets from Port Saint Lucie, FL to Lafayette, LA, with $104. Evening is the most expensive time of the day with prices starting from $133.

How to save money travelling from Port Saint Lucie, FL to Lafayette, LA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Port Saint Lucie, FL to Lafayette, LA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Port Saint Lucie, FL to Lafayette, LA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Port Saint Lucie, FL to Lafayette, LA are also emptier.

All bus stations and stops in Port Saint Lucie, FL and Lafayette, LA

In the map below, you can see where to find all bus stations in Port Saint Lucie, FL and Lafayette, LA.

Service and Comfort on the bus from Port Saint Lucie, FL to Lafayette, LA

Want to know which seat classes are available on the buses from Port Saint Lucie, FL to Lafayette, LA? Or which bus companies serve the route Port Saint Lucie, FL to Lafayette, LA? Below you will find answers to your questions.

FAQs about the Port Saint Lucie, FL to Lafayette, LA bus

How much does a Port Saint Lucie, FL Lafayette, LA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $104 and takes 25h 20m to reach Lafayette, LA. Compare offers to save money!

How much could I save by comparing buses from Port Saint Lucie, FL to Lafayette, LA?

This route is offered by 2 companies with a range of ticket prices between $104 and $165. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lafayette, LA.

On average, how many connections are available from Port Saint Lucie, FL to Lafayette, LA each day?

Every day, the Port Saint Lucie, FL to Lafayette, LA bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Port Saint Lucie, FL to Lafayette, LA take?

The fastest bus from Port Saint Lucie, FL to Lafayette, LA is offered by Greyhound US and takes 22h 10m. Bus tickets for this connection cost $104. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Port Saint Lucie, FL to Lafayette, LA?

The earliest bus arriving in Lafayette, LA from Port Saint Lucie, FL starts at 8:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Port Saint Lucie, FL to Lafayette, LA?

The latest bus trip departing from Port Saint Lucie, FL for Lafayette, LA starts at 6:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Port Saint Lucie, FL Lafayette, LA route?

When traveling by bus from Port Saint Lucie, FL to Lafayette, LA, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Port Saint Lucie, FL and Lafayette, LA?

You can check all the direct connections between Port Saint Lucie, FL and Lafayette, LA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Port Saint Lucie, FL to Lafayette, LA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Port Saint Lucie, FL Lafayette, LA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Port Saint Lucie, FL Lafayette, LA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Port Saint Lucie, FL to Lafayette, LA on your planned travel date.

Available seat classes which are offered on the bus route Port Saint Lucie, FL to Lafayette, LA

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Port Saint Lucie, FL and to Lafayette, LA

Here’s an overview of the most popular bus routes to Port Saint Lucie, FL and to Lafayette, LA. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Port Saint Lucie, FL and to Lafayette, LA
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