Bus Port Saint Lucie, FL to Jacksonville, FL: Compare prices and save money

Compare all timetables for the bus from Port Saint Lucie, FL to Jacksonville, FL

Here is a selection of the cheapest bus trips from the schedule from Port Saint Lucie, FL to Jacksonville, FL from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$37

Tuesday

$36

Wednesday

Thursday

$29

Friday

$37

Saturday

$37

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	6h 15m	8:45 AM	Port Saint Lucie, FL	RaceTrac Gas Station	3:00 PM	Jacksonville, FL	Amtrak Train Station		Economy	$37	A Bus from Greyhound US goes from RaceTrac Gas Station, Port Saint Lucie, FL (USA) at 7/27/2026 8:45:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 7/27/2026 3:00:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 6h 15m
	FlixBus	6h 5m	1:40 AM	Port Saint Lucie, FL	RaceTrac Gas Station	7:45 AM	Jacksonville, FL	Amtrak Train Station		Economy	$53	A Bus from FlixBus goes from RaceTrac Gas Station, Port Saint Lucie, FL (USA) at 7/27/2026 1:40:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 7/27/2026 7:45:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 6h 5m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	6h 15m	8:45 AM	Port Saint Lucie, FL	RaceTrac Gas Station	3:00 PM	Jacksonville, FL	Amtrak Train Station		Economy	$36	A Bus from Greyhound US goes from RaceTrac Gas Station, Port Saint Lucie, FL (USA) at 7/28/2026 8:45:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 7/28/2026 3:00:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 6h 15m
	FlixBus	7h 10m	1:40 AM	Port Saint Lucie, FL	RaceTrac Gas Station	8:50 AM	Jacksonville, FL	Amtrak Train Station		Economy	$47	A Bus from FlixBus goes from RaceTrac Gas Station, Port Saint Lucie, FL (USA) at 7/28/2026 1:40:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 7/28/2026 8:50:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 7h 10m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	6h 15m	8:45 AM	Port Saint Lucie, FL	SW Gatlin Blvd & SW Brescia St Bus Stop	3:00 PM	Jacksonville, FL	Downtown Bus Stop		Economy	$29	A Bus from Greyhound US goes from SW Gatlin Blvd & SW Brescia St Bus Stop, Port Saint Lucie, FL (USA) at 7/30/2026 8:45:00 AM to Downtown Bus Stop, Jacksonville, FL (USA) arriving at 7/30/2026 3:00:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 6h 15m
	FlixBus	6h 5m	1:40 AM	Port Saint Lucie, FL	SW Gatlin Blvd & SW Brescia St Bus Stop	7:45 AM	Jacksonville, FL	Downtown Bus Stop		Economy	$41	A Bus from FlixBus goes from SW Gatlin Blvd & SW Brescia St Bus Stop, Port Saint Lucie, FL (USA) at 7/30/2026 1:40:00 AM to Downtown Bus Stop, Jacksonville, FL (USA) arriving at 7/30/2026 7:45:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 6h 5m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	6h 15m	8:45 AM	Port Saint Lucie, FL	RaceTrac Gas Station	3:00 PM	Jacksonville, FL	Amtrak Train Station		Economy	$37	A Bus from Greyhound US goes from RaceTrac Gas Station, Port Saint Lucie, FL (USA) at 7/31/2026 8:45:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 7/31/2026 3:00:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 6h 15m
	FlixBus	6h 5m	1:40 AM	Port Saint Lucie, FL	RaceTrac Gas Station	7:45 AM	Jacksonville, FL	Amtrak Train Station		Economy	$46	A Bus from FlixBus goes from RaceTrac Gas Station, Port Saint Lucie, FL (USA) at 7/31/2026 1:40:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 7/31/2026 7:45:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 6h 5m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	6h 15m	8:45 AM	Port Saint Lucie, FL	RaceTrac Gas Station	3:00 PM	Jacksonville, FL	Amtrak Train Station		Economy	$37	A Bus from Greyhound US goes from RaceTrac Gas Station, Port Saint Lucie, FL (USA) at 8/1/2026 8:45:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 8/1/2026 3:00:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 6h 15m
	FlixBus	6h 5m	1:40 AM	Port Saint Lucie, FL	RaceTrac Gas Station	7:45 AM	Jacksonville, FL	Amtrak Train Station		Economy	$54	A Bus from FlixBus goes from RaceTrac Gas Station, Port Saint Lucie, FL (USA) at 8/1/2026 1:40:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 8/1/2026 7:45:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 6h 5m

Frequency of bus connections between Port Saint Lucie, FL and Jacksonville, FL

See here how frequent the connections between Port Saint Lucie, FL and Jacksonville, FL are, during different times and days of the week.

Thursday is the busiest day, with more than 4 daily buses from Port Saint Lucie, FL to Jacksonville, FL. Monday has instead the fewest connections, with only 2 daily coaches between Port Saint Lucie, FL and Jacksonville, FL.

The busiest time of the day is the Morning, with 6 buses from Port Saint Lucie, FL to Jacksonville, FL, while Morning sees the fewest connections between Port Saint Lucie, FL and Jacksonville, FL, with 6 offers.

Test cheapest views

The cheapest bus for the 7/30/2026 costs just $29, from Greyhound US

Facts about the bus from Port Saint Lucie, FL to Jacksonville, FL

Compare all providers like FlixBus and Greyhound US that travel 2 times every day by bus from Port Saint Lucie, FL to Jacksonville, FL in one click! Book your bus ticket from Port Saint Lucie, FL to Jacksonville, FL starting from $29!

Cheapest Bus	$29
Fastest Bus	6h 5m
Earliest Bus	1:40 AM
Latest Bus	8:45 AM
Daily Bus Routes	2 Ø
Distance	225.7 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Port Saint Lucie, FL to Jacksonville, FL

Every day, 2 buses from 2 bus companies leave Port Saint Lucie, FL for Jacksonville, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

Monday 07/27

$37

Tuesday 07/28

$36

Wednesday 07/29

Thursday 07/30

$33

Friday 07/31

$37

Saturday 08/01

$37

Sunday 08/02

$38

Monday 08/03

$32

Tuesday 08/04

Wednesday 08/05

$29

Thursday 08/06

$29

Friday 08/07

Saturday 08/08

Sunday 08/09

$38

Monday 08/10

$31

Tuesday 08/11

Wednesday 08/12

$30

Thursday 08/13

Friday 08/14

Saturday 08/15

Sunday 08/16

Monday 08/17

Tuesday 08/18

Wednesday 08/19

Thursday 08/20

Friday 08/21

Saturday 08/22

The cheapest time to travel from Port Saint Lucie, FL to Jacksonville, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Port Saint Lucie, FL to Jacksonville, FL, for the next 30 days.

With a price starting from $29, Thursday is the cheapest day for a bus from Port Saint Lucie, FL to Jacksonville, FL. Friday instead is the most expensive day with prices starting from $37.

Morning is the cheapest day time for bus tickets from Port Saint Lucie, FL to Jacksonville, FL, with $29. Morning is the most expensive time of the day with prices starting from $29.

How to save money travelling from Port Saint Lucie, FL to Jacksonville, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Port Saint Lucie, FL to Jacksonville, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Port Saint Lucie, FL to Jacksonville, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Port Saint Lucie, FL to Jacksonville, FL are also emptier.

All bus stations and stops in Port Saint Lucie, FL and Jacksonville, FL

In the map below, you can see where to find all bus stations in Port Saint Lucie, FL and Jacksonville, FL.

Fort Pierce Service Plaza

Florida Turnpike Mile Marker 144

SW Gatlin Blvd & SW Brescia St Bus Stop

RaceTrac Gas Station

SW Gatlin Blvd 2031

Shell Gas Station

SW Saint Lucie West Blvd 1795

Downtown Bus Stop

West Forsyth Street 1111

Beaver St. & Ocean St. Bus Stop

Central Bus Station

Old St. Augustine Rd

Old St. Augustine Rd 10584-13

Friendship Fountain

Service and Comfort on the bus from Port Saint Lucie, FL to Jacksonville, FL

Want to know which seat classes are available on the buses from Port Saint Lucie, FL to Jacksonville, FL? Or which bus companies serve the route Port Saint Lucie, FL to Jacksonville, FL? Below you will find answers to your questions.

FAQs about the Port Saint Lucie, FL to Jacksonville, FL bus

How much does a Port Saint Lucie, FL Jacksonville, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $29 and takes 6h 15m to reach Jacksonville, FL. Compare offers to save money!

How much could I save by comparing buses from Port Saint Lucie, FL to Jacksonville, FL?

This route is offered by 2 companies with a range of ticket prices between $29 and $54. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Jacksonville, FL.

On average, how many connections are available from Port Saint Lucie, FL to Jacksonville, FL each day?

Every day, the Port Saint Lucie, FL to Jacksonville, FL bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Port Saint Lucie, FL to Jacksonville, FL take?

The fastest bus from Port Saint Lucie, FL to Jacksonville, FL is offered by FlixBus and takes 6h 5m. Bus tickets for this connection cost $53. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Port Saint Lucie, FL to Jacksonville, FL?

The earliest bus arriving in Jacksonville, FL from Port Saint Lucie, FL starts at 1:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Port Saint Lucie, FL to Jacksonville, FL?

The latest bus trip departing from Port Saint Lucie, FL for Jacksonville, FL starts at 8:45 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Port Saint Lucie, FL Jacksonville, FL route?

When traveling by bus from Port Saint Lucie, FL to Jacksonville, FL, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Port Saint Lucie, FL and Jacksonville, FL?

You can check all the direct connections between Port Saint Lucie, FL and Jacksonville, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Port Saint Lucie, FL to Jacksonville, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Port Saint Lucie, FL Jacksonville, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Port Saint Lucie, FL Jacksonville, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Port Saint Lucie, FL to Jacksonville, FL on your planned travel date.

Available seat classes which are offered on the bus route Port Saint Lucie, FL to Jacksonville, FL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Port Saint Lucie, FL and to Jacksonville, FL

Here’s an overview of the most popular bus routes to Port Saint Lucie, FL and to Jacksonville, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!