Bus Pittsburgh to Chicago: Compare prices and save money

Compare all timetables for the bus from Pittsburgh to Chicago

Here is a selection of the cheapest bus trips from the schedule from Pittsburgh to Chicago from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

Thursday

Friday

$60

Saturday

$55

Sunday

Monday

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	10h 5m	12:55 AM	Pittsburgh	Grant Street Transportation Center	10:00 AM	Chicago	Downtown Bus Station	Economy	$60	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 9/11/2026 12:55:00 AM to Downtown Bus Station, Chicago (USA) arriving at 9/11/2026 10:00:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 10h 5m
Greyhound US	13h 0m	1:25 AM	Pittsburgh	Grant Street Transportation Center	1:25 PM	Chicago	Downtown Bus Station	Economy	$60	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 9/11/2026 1:25:00 AM to Downtown Bus Station, Chicago (USA) arriving at 9/11/2026 1:25:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 13h 0m
Greyhound US	12h 30m	8:35 AM	Pittsburgh	Grant Street Transportation Center	8:05 PM	Chicago	Downtown Bus Station	Economy	$60	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 9/11/2026 8:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 9/11/2026 8:05:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 12h 30m
FlixBus	11h 25m	7:45 PM	Pittsburgh	Grant Street Transportation Center	6:10 AM	Chicago	Downtown Bus Station	Economy	$72	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 9/11/2026 7:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 9/12/2026 6:10:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 11h 25m
FlixBus	10h 55m	7:45 PM	Pittsburgh	Grant Street Transportation Center	5:40 AM	Chicago	95th Red Line Station	Economy	$78	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 9/11/2026 7:45:00 PM to 95th Red Line Station, Chicago (USA) arriving at 9/12/2026 5:40:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 10h 55m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	13h 0m	1:25 AM	Pittsburgh	Grant Street Transportation Center	1:25 PM	Chicago	Downtown Bus Station	Economy	$55	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 9/12/2026 1:25:00 AM to Downtown Bus Station, Chicago (USA) arriving at 9/12/2026 1:25:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 13h 0m
Greyhound US	12h 15m	8:50 AM	Pittsburgh	Grant Street Transportation Center	8:05 PM	Chicago	Downtown Bus Station	Economy	$55	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 9/12/2026 8:50:00 AM to Downtown Bus Station, Chicago (USA) arriving at 9/12/2026 8:05:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 12h 15m
Greyhound US	10h 5m	12:55 AM	Pittsburgh	Grant Street Transportation Center	10:00 AM	Chicago	Downtown Bus Station	Economy	$59	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 9/12/2026 12:55:00 AM to Downtown Bus Station, Chicago (USA) arriving at 9/12/2026 10:00:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 10h 5m
FlixBus	11h 25m	7:45 PM	Pittsburgh	Grant Street Transportation Center	6:10 AM	Chicago	Downtown Bus Station	Economy	$59	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 9/12/2026 7:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 9/13/2026 6:10:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 11h 25m
FlixBus	12h 55m	7:00 AM	Pittsburgh	Grant Street Transportation Center	6:55 PM	Chicago	Downtown Bus Station	Economy	$68	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 9/12/2026 7:00:00 AM to Downtown Bus Station, Chicago (USA) arriving at 9/12/2026 6:55:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 12h 55m

Frequency of bus connections between Pittsburgh and Chicago

See here how frequent the connections between Pittsburgh and Chicago are, during different times and days of the week.

Friday is the busiest day, with more than 26 daily buses from Pittsburgh to Chicago. Friday has instead the fewest connections, with only 26 daily coaches between Pittsburgh and Chicago.

The busiest time of the day is the Evening, with 20 buses from Pittsburgh to Chicago, while Morning sees the fewest connections between Pittsburgh and Chicago, with 16 offers.

Test cheapest views

The cheapest bus for the 9/26/2026 costs just $53, from Greyhound US

Facts about the bus from Pittsburgh to Chicago

Compare all providers like Greyhound US and FlixBus that travel 26 times every day by bus from Pittsburgh to Chicago in one click! Book your bus ticket from Pittsburgh to Chicago starting from $53!

Cheapest Bus	$53
Fastest Bus	9h 5m
Earliest Bus	12:55 AM
Latest Bus	8:00 PM
Daily Bus Routes	26 Ø
Distance	409.7 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Pittsburgh to Chicago

Every day, 26 buses from 2 bus companies leave Pittsburgh for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/08/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

$74

Wednesday 09/09

Thursday 09/10

Friday 09/11

$60

Saturday 09/12

$58

Sunday 09/13

Monday 09/14

Tuesday 09/15

Wednesday 09/16

Thursday 09/17

Friday 09/18

Saturday 09/19

Sunday 09/20

Monday 09/21

$70

Tuesday 09/22

Wednesday 09/23

Thursday 09/24

Friday 09/25

Saturday 09/26

$53

Sunday 09/27

$73

Monday 09/28

Tuesday 09/29

Wednesday 09/30

Thursday 10/01

Friday 10/02

Saturday 10/03

The cheapest time to travel from Pittsburgh to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Pittsburgh to Chicago, for the next 30 days.

With a price starting from $53, Saturday is the cheapest day for a bus from Pittsburgh to Chicago. Friday instead is the most expensive day with prices starting from $60.

Night is the cheapest day time for bus tickets from Pittsburgh to Chicago, with $53. Evening is the most expensive time of the day with prices starting from $59.

How to save money travelling from Pittsburgh to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Pittsburgh to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Pittsburgh to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Pittsburgh to Chicago are also emptier.

All bus stations and stops in Pittsburgh and Chicago

In the map below, you can see where to find all bus stations in Pittsburgh and Chicago.

Grant Street Transportation Center

11th St 55

David L. Lawrence Convention Center

10th St Pittsburgh 131-199

Carnegie Mellon

Forbes Ave

University of

Bus Stop

Forbes Ave 3501

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Pittsburgh to Chicago

Want to know which seat classes are available on the buses from Pittsburgh to Chicago? Or which bus companies serve the route Pittsburgh to Chicago? Below you will find answers to your questions.

FAQs about the Pittsburgh to Chicago bus

How much does a Pittsburgh Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $53 and takes 11h 15m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Pittsburgh to Chicago?

This route is offered by 2 companies with a range of ticket prices between $53 and $107. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Pittsburgh to Chicago each day?

Every day, the Pittsburgh to Chicago bus route is served by approximately 26 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Pittsburgh to Chicago take?

The fastest bus from Pittsburgh to Chicago is offered by Greyhound US and takes 9h 5m. Bus tickets for this connection cost $62. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Pittsburgh to Chicago?

The earliest bus arriving in Chicago from Pittsburgh starts at 12:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Pittsburgh to Chicago?

The latest bus trip departing from Pittsburgh for Chicago starts at 8:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Pittsburgh Chicago route?

When traveling by bus from Pittsburgh to Chicago, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Pittsburgh and Chicago?

You can check all the direct connections between Pittsburgh and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Pittsburgh to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Pittsburgh Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Pittsburgh Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Pittsburgh to Chicago on your planned travel date.

Available seat classes which are offered on the bus route Pittsburgh to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Pittsburgh and to Chicago

Here’s an overview of the most popular bus routes to Pittsburgh and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!