Which bus from Mexico City to Santiago Tuxtla is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $72
Search for your destination Millions of deals worldwide
Compare results Save up to 70%
Find the right bus for you Easy and transparent

Compare all timetables for the bus from Mexico City to Santiago Tuxtla

Here is a selection of the cheapest bus trips from the schedule from Mexico City to Santiago Tuxtla from various bus operators like ADO for the next days.

today
$72
tomorrow
Wednesday
$72
Thursday
$72
Friday
$72
Saturday
Sunday
$72

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ADO 9h 20m 8:00 PM Mexico City Norte Bus Station 5:20 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 9h 19m 11:10 PM Mexico City Norte Bus Station 8:29 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 8h 15m 9:05 PM Mexico City Terminal de Autobuses de Oriente (TAPO) 5:20 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 8h 20m 10:01 PM Mexico City Norte Bus Station 6:21 AM Santiago Tuxtla Central Bus Station  Economy $73
ADO 7h 30m 10:51 PM Mexico City Terminal de Autobuses de Oriente (TAPO) 6:21 AM Santiago Tuxtla Central Bus Station  Economy $73
  • Did you know that if you travel from Mexico City to Santiago Tuxtla via Veracruz, you can save more than $19? You can find the corresponding connections below.
    • Conexión
      10h 45m
      0
      9:15 AM
      Mexico City
      Norte Bus Station
      4:51 PM
      Veracruz
      Bus Stop
      0
      Conexión
      Economy
      $34
      • Waiting Time 0h 4m
    • ADO
      3h 5m
      0
      4:55 PM
      Veracruz
      Central bus station
      8:00 PM
      Santiago Tuxtla
      Central Bus Station
      0
      ADO
      Economy
      $19
    Travel time is 3h 15m longer, but you will save $19

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ADO 8h 45m 12:04 AM Mexico City Terminal de Autobuses de Oriente (TAPO) 8:49 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 8h 15m 9:05 PM Mexico City Terminal de Autobuses de Oriente (TAPO) 5:20 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 9h 20m 8:00 PM Mexico City Norte Bus Station 5:20 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 8h 20m 10:01 PM Mexico City Norte Bus Station 6:21 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 9h 19m 11:10 PM Mexico City Norte Bus Station 8:29 AM Santiago Tuxtla Central Bus Station  Economy $72
  • Did you know that if you travel from Mexico City to Santiago Tuxtla via Veracruz, you can save more than $19? You can find the corresponding connections below.
    • Conexión
      10h 45m
      0
      9:15 AM
      Mexico City
      Norte Bus Station
      4:51 PM
      Veracruz
      Bus Stop
      0
      Conexión
      Economy
      $34
      • Waiting Time 0h 4m
    • ADO
      3h 5m
      0
      4:55 PM
      Veracruz
      Central bus station
      8:00 PM
      Santiago Tuxtla
      Central Bus Station
      0
      ADO
      Economy
      $19
    Travel time is 2h 30m longer, but you will save $19

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ADO 8h 25m 12:04 AM Mexico City Terminal de Autobuses de Oriente (TAPO) 8:29 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 8h 15m 9:05 PM Mexico City Terminal de Autobuses de Oriente (TAPO) 5:20 AM Santiago Tuxtla Central Bus Station  Economy $72
  • Did you know that if you travel from Mexico City to Santiago Tuxtla via Veracruz, you can save more than $19? You can find the corresponding connections below.
    • Conexión
      10h 45m
      0
      9:15 AM
      Mexico City
      Norte Bus Station
      4:51 PM
      Veracruz
      Bus Stop
      0
      Conexión
      Economy
      $34
      • Waiting Time 0h 4m
    • ADO
      3h 5m
      0
      4:55 PM
      Veracruz
      Central bus station
      8:00 PM
      Santiago Tuxtla
      Central Bus Station
      0
      ADO
      Economy
      $19
    Travel time is 2h 30m longer, but you will save $19

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ADO 9h 20m 8:00 PM Mexico City Norte Bus Station 5:20 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 9h 19m 11:10 PM Mexico City Norte Bus Station 8:29 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 8h 20m 10:01 PM Mexico City Norte Bus Station 6:21 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 8h 25m 12:04 AM Mexico City Terminal de Autobuses de Oriente (TAPO) 8:29 AM Santiago Tuxtla Central Bus Station  Economy $73
ADO 8h 15m 9:05 PM Mexico City Terminal de Autobuses de Oriente (TAPO) 5:20 AM Santiago Tuxtla Central Bus Station  Economy $73
  • Did you know that if you travel from Mexico City to Santiago Tuxtla via Veracruz, you can save more than $19? You can find the corresponding connections below.
    • Conexión
      10h 45m
      0
      9:15 AM
      Mexico City
      Norte Bus Station
      4:51 PM
      Veracruz
      Bus Stop
      0
      Conexión
      Economy
      $34
      • Waiting Time 0h 4m
    • ADO
      3h 5m
      0
      4:55 PM
      Veracruz
      Central bus station
      8:00 PM
      Santiago Tuxtla
      Central Bus Station
      0
      ADO
      Economy
      $19
    Travel time is 2h 30m longer, but you will save $19

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ADO 8h 25m 12:04 AM Mexico City Terminal de Autobuses de Oriente (TAPO) 8:29 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 7h 55m 9:05 PM Mexico City Terminal de Autobuses de Oriente (TAPO) 5:00 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 8h 55m 10:15 PM Mexico City Terminal de Autobuses de Oriente (TAPO) 7:10 AM Santiago Tuxtla Central Bus Station  Economy $72
ADO 9h 0m 8:00 PM Mexico City Norte Bus Station 5:00 AM Santiago Tuxtla Central Bus Station  Economy $73
ADO 9h 19m 11:10 PM Mexico City Norte Bus Station 8:29 AM Santiago Tuxtla Central Bus Station  Economy $73
  • Did you know that if you travel from Mexico City to Santiago Tuxtla via Veracruz, you can save more than $20? You can find the corresponding connections below.
    • Conexión
      11h 40m
      0
      7:15 AM
      Mexico City
      Norte Bus Station
      2:57 PM
      Veracruz
      Bus Stop
      0
      Conexión
      Economy
      $33
      • Waiting Time 1h 8m
    • ADO
      2h 50m
      0
      4:05 PM
      Veracruz
      Central bus station
      6:55 PM
      Santiago Tuxtla
      Central Bus Station
      0
      ADO
      Economy
      $19
    Travel time is 3h 45m longer, but you will save $20

Best Price Offer: The price for the cheapest bus from Mexico City to Santiago Tuxtla is $72 on 7/27/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Mexico City and Santiago Tuxtla

See here how frequent the connections between Mexico City and Santiago Tuxtla are, during different times and days of the week.
Wednesday is the busiest day, with more than 9 daily buses from Mexico City to Santiago Tuxtla. Thursday has instead the fewest connections, with only 2 daily coaches between Mexico City and Santiago Tuxtla.
The busiest time of the day is the Evening, with 29 buses from Mexico City to Santiago Tuxtla, while Night sees the fewest connections between Mexico City and Santiago Tuxtla, with 6 offers.

Facts about the bus from Mexico City to Santiago Tuxtla

Compare all providers like ADO that travel 7 times every day by bus from Mexico City to Santiago Tuxtla in one click! Book your bus ticket from Mexico City to Santiago Tuxtla starting from $72!

Cheapest Bus $72
Fastest Bus 7h 30m
Earliest Bus 8:00 PM
Latest Bus 11:10 PM
Daily Bus Routes 7 Ø
Distance 259.2 miles
Bus Companies ADO

Cheapest bus connections from Mexico City to Santiago Tuxtla

Every day, 7 buses from 1 bus companies leave Mexico City for Santiago Tuxtla: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/26
Monday 07/27
$72
Tuesday 07/28
Wednesday 07/29
$72
Thursday 07/30
$72
Friday 07/31
$75
Saturday 08/01
Sunday 08/02
$73
Monday 08/03
$72
Tuesday 08/04
$72
Wednesday 08/05
Thursday 08/06
Friday 08/07
$72
Saturday 08/08
$72
Sunday 08/09
$73
Monday 08/10
$73
Tuesday 08/11
$72
Wednesday 08/12
Thursday 08/13
Friday 08/14
Saturday 08/15
$75
Sunday 08/16
$72
Monday 08/17
Tuesday 08/18
$72
Wednesday 08/19
Thursday 08/20
Friday 08/21
Saturday 08/22

The cheapest time to travel from Mexico City to Santiago Tuxtla

See here on which day and which time of the day you can find the cheapest bus ticket from Mexico City to Santiago Tuxtla, for the next 30 days.
With a price starting from $71, Thursday is the cheapest day for a bus from Mexico City to Santiago Tuxtla. Sunday instead is the most expensive day with prices starting from $72.
Evening is the cheapest day time for bus tickets from Mexico City to Santiago Tuxtla, with $72. Evening is the most expensive time of the day with prices starting from $72.

How to save money travelling from Mexico City to Santiago Tuxtla

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mexico City to Santiago Tuxtla in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mexico City to Santiago Tuxtla, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mexico City to Santiago Tuxtla are also emptier.

All bus stations and stops in Mexico City and Santiago Tuxtla

In the map below, you can see where to find all bus stations in Mexico City and Santiago Tuxtla.

Service and Comfort on the bus from Mexico City to Santiago Tuxtla

Want to know which seat classes are available on the buses from Mexico City to Santiago Tuxtla? Or which bus companies serve the route Mexico City to Santiago Tuxtla? Below you will find answers to your questions.

FAQs about the Mexico City to Santiago Tuxtla bus

How much does a Mexico City Santiago Tuxtla bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $72 and takes 9h 20m to reach Santiago Tuxtla. Compare offers to save money!

How much could I save by comparing buses from Mexico City to Santiago Tuxtla?

This route is offered by 1 companies with a range of ticket prices between $72 and $73. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago Tuxtla.

On average, how many connections are available from Mexico City to Santiago Tuxtla each day?

Every day, the Mexico City to Santiago Tuxtla bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mexico City to Santiago Tuxtla take?

The fastest bus from Mexico City to Santiago Tuxtla is offered by ADO and takes 7h 30m. Bus tickets for this connection cost $73. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mexico City to Santiago Tuxtla?

The earliest bus arriving in Santiago Tuxtla from Mexico City starts at 8:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mexico City to Santiago Tuxtla?

The latest bus trip departing from Mexico City for Santiago Tuxtla starts at 11:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mexico City Santiago Tuxtla route?

When traveling by bus from Mexico City to Santiago Tuxtla, passengers can travel with ADO. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mexico City and Santiago Tuxtla?

You can check all the direct connections between Mexico City and Santiago Tuxtla by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ADO.

What can I take with me on the Mexico City to Santiago Tuxtla bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mexico City Santiago Tuxtla bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mexico City Santiago Tuxtla bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mexico City to Santiago Tuxtla on your planned travel date.

Available seat classes which are offered on the bus route Mexico City to Santiago Tuxtla

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mexico City and to Santiago Tuxtla

Here’s an overview of the most popular bus routes to Mexico City and to Santiago Tuxtla. Simply click on the connection of your choice, and you will find all the details about your bus route!
Veracruz to Santiago Tuxtla bus Veracruz to Santiago Tuxtla bus
Bus Puebla City, PL to Santiago Tuxtla Bus Puebla City, PL to Santiago Tuxtla
Buses Celaya to Mexico City Buses Celaya to Mexico City
General Escobedo to Mexico City bus General Escobedo to Mexico City bus
Villahermosa to Mexico City bus Villahermosa to Mexico City bus
From Las Vegas to Mexico City bus From Las Vegas to Mexico City bus
Buses Cancún to Mexico City Buses Cancún to Mexico City
Buses Memphis - Mexico City Buses Memphis - Mexico City
Bus to Mexico City from Tlalnepantla de Baz, ME Bus to Mexico City from Tlalnepantla de Baz, ME
Bus Guadalupe, NL - Mexico City Bus Guadalupe, NL - Mexico City
Bus from El Paso, TX to Mexico City Bus from El Paso, TX to Mexico City
Buses Washington, DC - Mexico City Buses Washington, DC - Mexico City
Bus from Hermosillo to Mexico City Bus from Hermosillo to Mexico City
Campeche to Mexico City bus Campeche to Mexico City bus
Buses to Mexico City from Columbus, OH Buses to Mexico City from Columbus, OH
Buses Fort Worth to Mexico City Buses Fort Worth to Mexico City
Buses Chihuahua to Mexico City Buses Chihuahua to Mexico City
Bus from Austin to Mexico City Bus from Austin to Mexico City
Bus from Mexicali to Mexico City Bus from Mexicali to Mexico City
Mérida, YN to Mexico City bus Mérida, YN to Mexico City bus
Buses Dallas - Mexico City Buses Dallas - Mexico City
From Ciudad Juárez to Mexico City bus From Ciudad Juárez to Mexico City bus
Buses to Mexico City from Tijuana, BC Buses to Mexico City from Tijuana, BC
Zapopan to Mexico City bus Zapopan to Mexico City bus
Popular Airport Shuttles to Mexico City and to Santiago Tuxtla
CheckMyBus › Buses in Mexico › Bus to Mexico City › Bus to Santiago Tuxtla

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.