Bus Mesa, AZ to Chicago: Compare prices and save money

Compare all timetables for the bus from Mesa, AZ to Chicago

Here is a selection of the cheapest bus trips from the schedule from Mesa, AZ to Chicago from various bus operators like Greyhound US for the next days.

today

$185

tomorrow

$147

Monday

Tuesday

Wednesday

Thursday

Friday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 10m	7:55 PM	Mesa, AZ	Greyhound	4:05 PM	Chicago	Downtown Bus Station	Economy	$185	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 9/5/2026 7:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 9/7/2026 4:05:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 42h 10m
Greyhound US	44h 30m	7:55 PM	Mesa, AZ	Greyhound	6:25 PM	Chicago	95th Red Line Station	Economy	$231	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 9/5/2026 7:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 9/7/2026 6:25:00 PM. 50 Economy ticket for $231 per person are available. Travel duration is 44h 30m
Greyhound US	58h 5m	7:55 PM	Mesa, AZ	Greyhound	8:00 AM	Chicago	Canal & Van Buren	Economy	$251	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 9/5/2026 7:55:00 PM to Canal & Van Buren, Chicago (USA) arriving at 9/8/2026 8:00:00 AM. 50 Economy ticket for $251 per person are available. Travel duration is 58h 5m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 40m	7:40 AM	Mesa, AZ	Greyhound	4:20 AM	Chicago	Downtown Bus Station	Economy	$147	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 9/6/2026 7:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 9/8/2026 4:20:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 42h 40m
Greyhound US	42h 10m	7:55 PM	Mesa, AZ	Greyhound	4:05 PM	Chicago	Downtown Bus Station	Economy	$164	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 9/6/2026 7:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 9/8/2026 4:05:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 42h 10m
Greyhound US	58h 5m	7:55 PM	Mesa, AZ	Greyhound	8:00 AM	Chicago	Canal & Van Buren	Economy	$172	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 9/6/2026 7:55:00 PM to Canal & Van Buren, Chicago (USA) arriving at 9/9/2026 8:00:00 AM. 50 Economy ticket for $172 per person are available. Travel duration is 58h 5m
Greyhound US	46h 20m	7:40 AM	Mesa, AZ	Greyhound	8:00 AM	Chicago	Canal & Van Buren	Economy	$217	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 9/6/2026 7:40:00 AM to Canal & Van Buren, Chicago (USA) arriving at 9/8/2026 8:00:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 46h 20m
Greyhound US	43h 30m	7:40 AM	Mesa, AZ	Greyhound	5:10 AM	Chicago	95th Red Line Station	Economy	$219	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 9/6/2026 7:40:00 AM to 95th Red Line Station, Chicago (USA) arriving at 9/8/2026 5:10:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 43h 30m

Frequency of bus connections between Mesa, AZ and Chicago

See here how frequent the connections between Mesa, AZ and Chicago are, during different times and days of the week.

Sunday is the busiest day, with more than 6 daily buses from Mesa, AZ to Chicago. Saturday has instead the fewest connections, with only 3 daily coaches between Mesa, AZ and Chicago.

The busiest time of the day is the Evening, with 6 buses from Mesa, AZ to Chicago, while Morning sees the fewest connections between Mesa, AZ and Chicago, with 3 offers.

Test cheapest views

The cheapest bus for the 9/21/2026 costs just $130, from Greyhound US

Facts about the bus from Mesa, AZ to Chicago

Compare all providers like Greyhound US that travel 4 times every day by bus from Mesa, AZ to Chicago in one click! Book your bus ticket from Mesa, AZ to Chicago starting from $130!

Cheapest Bus	$130
Fastest Bus	44h 10m
Earliest Bus	7:55 PM
Latest Bus	7:55 PM
Daily Bus Routes	4 Ø
Distance	1,440.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Mesa, AZ to Chicago

Every day, 4 buses from 1 bus companies leave Mesa, AZ for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/05/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/30

Monday 08/31

Tuesday 09/01

Wednesday 09/02

Thursday 09/03

Friday 09/04

Saturday 09/05

$183

Sunday 09/06

$147

Monday 09/07

Tuesday 09/08

Wednesday 09/09

Thursday 09/10

Friday 09/11

Saturday 09/12

Sunday 09/13

Monday 09/14

Tuesday 09/15

Wednesday 09/16

Thursday 09/17

Friday 09/18

Saturday 09/19

Sunday 09/20

Monday 09/21

$130

Tuesday 09/22

Wednesday 09/23

Thursday 09/24

Friday 09/25

Saturday 09/26

The cheapest time to travel from Mesa, AZ to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Mesa, AZ to Chicago, for the next 30 days.

With a price starting from $147, Sunday is the cheapest day for a bus from Mesa, AZ to Chicago. Saturday instead is the most expensive day with prices starting from $183.

Morning is the cheapest day time for bus tickets from Mesa, AZ to Chicago, with $147. Evening is the most expensive time of the day with prices starting from $164.

How to save money travelling from Mesa, AZ to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mesa, AZ to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mesa, AZ to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mesa, AZ to Chicago are also emptier.

All bus stations and stops in Mesa, AZ and Chicago

In the map below, you can see where to find all bus stations in Mesa, AZ and Chicago.

Greyhound

S Country Club Dr 1423

Fry’s Fuel Center

W Main Street 1235

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Mesa, AZ to Chicago

Want to know which seat classes are available on the buses from Mesa, AZ to Chicago? Or which bus companies serve the route Mesa, AZ to Chicago? Below you will find answers to your questions.

FAQs about the Mesa, AZ to Chicago bus

How much does a Mesa, AZ Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $130 and takes 44h 40m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Mesa, AZ to Chicago?

This route is offered by 1 companies with a range of ticket prices between $130 and $251. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Mesa, AZ to Chicago each day?

Every day, the Mesa, AZ to Chicago bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mesa, AZ to Chicago take?

The fastest bus from Mesa, AZ to Chicago is offered by Greyhound US and takes 44h 10m. Bus tickets for this connection cost $185. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mesa, AZ to Chicago?

The earliest bus arriving in Chicago from Mesa, AZ starts at 7:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mesa, AZ to Chicago?

The latest bus trip departing from Mesa, AZ for Chicago starts at 7:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mesa, AZ Chicago route?

When traveling by bus from Mesa, AZ to Chicago, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mesa, AZ and Chicago?

You can check all the direct connections between Mesa, AZ and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mesa, AZ to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mesa, AZ Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mesa, AZ Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mesa, AZ to Chicago on your planned travel date.

Available seat classes which are offered on the bus route Mesa, AZ to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mesa, AZ and to Chicago

Here’s an overview of the most popular bus routes to Mesa, AZ and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!