Bus McAllen, TX to Santiago de Queretaro

Compare all timetables for the bus from McAllen, TX to Santiago de Queretaro

Here is a selection of the cheapest bus trips from the schedule from McAllen, TX to Santiago de Queretaro from various bus operators like Greyhound US, FlixBus or Greyhound Lines Mexico for the next days.

today

$67

tomorrow

Wednesday

Thursday

$69

Friday

$68

Saturday

Sunday

$73

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	21h 15m	9:30 AM	McAllen, TX	Central Bus Station	5:45 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop		Economy	$67	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/27/2026 9:30:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 7/28/2026 5:45:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 21h 15m
	Greyhound US	18h 40m	4:25 PM	McAllen, TX	Central Bus Station	10:05 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop		Economy	$67	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/27/2026 4:25:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 7/28/2026 10:05:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 18h 40m

Did you know that if you travel from McAllen, TX to Santiago de Queretaro via General Escobedo, you can save more than $9? You can find the corresponding connections below.
- Greyhound US
  
  21h 20m
  
  0
  
  4:25 PM
  
  McAllen, TX
  Central Bus Station
  
  7:25 PM
  
  General Escobedo
  Central Bus Station
  
  0
  
  Economy
  
  $15
  
  A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/28/2026 4:25:00 PM to Central Bus Station, General Escobedo (Mexico) arriving at 7/28/2026 7:25:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 0m
- Flix Mexico
  
  14h 40m
  
  0
  
  10:05 PM
  
  General Escobedo
  Central Bus Station
  
  12:45 PM
  
  Santiago de Queretaro
  Prol Zaragoza Y City Club Las Plazas Bus Stop
  
  0
  
  Economy
  
  $43
  
  A Bus from Flix Mexico goes from Central Bus Station, General Escobedo (Mexico) at 7/28/2026 10:05:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 7/29/2026 12:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 14h 40m
Travel time is 3h 40m longer, but you will save $9

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	21h 15m	9:30 AM	McAllen, TX	Central Bus Station	5:45 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop		Economy	$69	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/30/2026 9:30:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 7/31/2026 5:45:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 21h 15m
	Greyhound US	18h 40m	4:25 PM	McAllen, TX	Central Bus Station	10:05 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop		Economy	$70	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/30/2026 4:25:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 7/31/2026 10:05:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 18h 40m

Did you know that if you travel from McAllen, TX to Santiago de Queretaro via Monterrey, NL, you can save more than $23? You can find the corresponding connections below.
- Greyhound Lines Mexico
  
  21h 20m
  
  0
  
  4:25 PM
  
  McAllen, TX
  Central Bus Station
  
  7:25 PM
  
  Monterrey, NL
  Sendero Bus Station
  
  0
  
  Economy
  
  $22
  
  A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 7/31/2026 4:25:00 PM to Sendero Bus Station, Monterrey, NL (Mexico) arriving at 7/31/2026 7:25:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 4h 0m
- Flix Mexico
  
  14h 20m
  
  0
  
  10:25 PM
  
  Monterrey, NL
  Sendero Bus Station
  
  12:45 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $24
  
  A Bus from Flix Mexico goes from Sendero Bus Station, Monterrey, NL (Mexico) at 7/31/2026 10:25:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 8/1/2026 12:45:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 14h 20m
Travel time is 3h 40m longer, but you will save $23

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	18h 40m	4:25 PM	McAllen, TX	Central Bus Station	10:05 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$68	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/31/2026 4:25:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/1/2026 10:05:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 18h 40m
FlixBus	28h 10m	11:00 PM	McAllen, TX	Central Bus Station	2:10 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$72	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 7/31/2026 11:00:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 8/2/2026 2:10:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 28h 10m
Greyhound US	21h 15m	9:30 AM	McAllen, TX	Central Bus Station	5:45 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$76	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/31/2026 9:30:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/1/2026 5:45:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 21h 15m

Did you know that if you travel from McAllen, TX to Santiago de Queretaro via Monterrey, NL, you can save more than $22? You can find the corresponding connections below.
- Greyhound Lines Mexico
  
  21h 20m
  
  0
  
  4:25 PM
  
  McAllen, TX
  Central Bus Station
  
  7:25 PM
  
  Monterrey, NL
  Sendero Bus Station
  
  0
  
  Economy
  
  $22
  
  A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 7/31/2026 4:25:00 PM to Sendero Bus Station, Monterrey, NL (Mexico) arriving at 7/31/2026 7:25:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 4h 0m
- Flix Mexico
  
  14h 20m
  
  0
  
  10:25 PM
  
  Monterrey, NL
  Sendero Bus Station
  
  12:45 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $24
  
  A Bus from Flix Mexico goes from Sendero Bus Station, Monterrey, NL (Mexico) at 7/31/2026 10:25:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 8/1/2026 12:45:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 14h 20m
Travel time is 3h 40m longer, but you will save $22

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	18h 40m	4:25 PM	McAllen, TX	Central Bus Station	10:05 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop		Economy	$73	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 8/2/2026 4:25:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/3/2026 10:05:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 18h 40m
	Greyhound US	21h 15m	9:30 AM	McAllen, TX	Central Bus Station	5:45 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop		Economy	$74	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 8/2/2026 9:30:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/3/2026 5:45:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 21h 15m

Did you know that if you travel from McAllen, TX to Santiago de Queretaro via Monterrey, NL, you can save more than $27? You can find the corresponding connections below.
- Greyhound Lines Mexico
  
  21h 20m
  
  0
  
  4:25 PM
  
  McAllen, TX
  Central Bus Station
  
  7:25 PM
  
  Monterrey, NL
  Sendero Bus Station
  
  0
  
  Economy
  
  $22
  
  A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 7/31/2026 4:25:00 PM to Sendero Bus Station, Monterrey, NL (Mexico) arriving at 7/31/2026 7:25:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 4h 0m
- Flix Mexico
  
  14h 20m
  
  0
  
  10:25 PM
  
  Monterrey, NL
  Sendero Bus Station
  
  12:45 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $24
  
  A Bus from Flix Mexico goes from Sendero Bus Station, Monterrey, NL (Mexico) at 7/31/2026 10:25:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 8/1/2026 12:45:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 14h 20m
Travel time is 3h 40m longer, but you will save $27

Best Price Offer: The price for the cheapest bus from McAllen, TX to Santiago de Queretaro is $63 on 7/28/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between McAllen, TX and Santiago de Queretaro

See here how frequent the connections between McAllen, TX and Santiago de Queretaro are, during different times and days of the week.

Friday is the busiest day, with more than 5 daily buses from McAllen, TX to Santiago de Queretaro. Sunday has instead the fewest connections, with only 2 daily coaches between McAllen, TX and Santiago de Queretaro.

The busiest time of the day is the Morning, with 5 buses from McAllen, TX to Santiago de Queretaro, while Evening sees the fewest connections between McAllen, TX and Santiago de Queretaro, with 1 offers.

Facts about the bus from McAllen, TX to Santiago de Queretaro

Compare all providers like Greyhound US, FlixBus and Greyhound Lines Mexico that travel 2 times every day by bus from McAllen, TX to Santiago de Queretaro in one click! Book your bus ticket from McAllen, TX to Santiago de Queretaro starting from $63!

Cheapest Bus	$63
Fastest Bus	17h 40m
Earliest Bus	9:30 AM
Latest Bus	4:25 PM
Daily Bus Routes	2 Ø
Distance	411.5 miles
Bus Companies	Greyhound US, FlixBus and Greyhound Lines Mexico

Cheapest bus connections from McAllen, TX to Santiago de Queretaro

Every day, 2 buses from 3 bus companies leave McAllen, TX for Santiago de Queretaro: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

Monday 07/27

$103

Tuesday 07/28

$63

Wednesday 07/29

$94

Thursday 07/30

$107

Friday 07/31

$103

Saturday 08/01

Sunday 08/02

$73

Monday 08/03

$97

Tuesday 08/04

$67

Wednesday 08/05

Thursday 08/06

Friday 08/07

$71

Saturday 08/08

$70

Sunday 08/09

$72

Monday 08/10

$80

Tuesday 08/11

Wednesday 08/12

$68

Thursday 08/13

$68

Friday 08/14

$66

Saturday 08/15

Sunday 08/16

$76

Monday 08/17

$84

Tuesday 08/18

Wednesday 08/19

Thursday 08/20

$71

Friday 08/21

Saturday 08/22

The cheapest time to travel from McAllen, TX to Santiago de Queretaro

See here on which day and which time of the day you can find the cheapest bus ticket from McAllen, TX to Santiago de Queretaro, for the next 30 days.

With a price starting from $66, Friday is the cheapest day for a bus from McAllen, TX to Santiago de Queretaro. Sunday instead is the most expensive day with prices starting from $72.

Morning is the cheapest day time for bus tickets from McAllen, TX to Santiago de Queretaro, with $67. Evening is the most expensive time of the day with prices starting from $71.

How to save money travelling from McAllen, TX to Santiago de Queretaro

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from McAllen, TX to Santiago de Queretaro in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from McAllen, TX to Santiago de Queretaro, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from McAllen, TX to Santiago de Queretaro are also emptier.

All bus stations and stops in McAllen, TX and Santiago de Queretaro

In the map below, you can see where to find all bus stations in McAllen, TX and Santiago de Queretaro.

Central Bus Station

U.S. 83 Business 1501

Frontera México-USA

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

El Colorado

Walmart Juriquilla

Service and Comfort on the bus from McAllen, TX to Santiago de Queretaro

Want to know which seat classes are available on the buses from McAllen, TX to Santiago de Queretaro? Or which bus companies serve the route McAllen, TX to Santiago de Queretaro? Below you will find answers to your questions.

FAQs about the McAllen, TX to Santiago de Queretaro bus

How much does a McAllen, TX Santiago de Queretaro bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $63 and takes 20h 15m to reach Santiago de Queretaro. Compare offers to save money!

How much could I save by comparing buses from McAllen, TX to Santiago de Queretaro?

This route is offered by 3 companies with a range of ticket prices between $63 and $80. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago de Queretaro.

On average, how many connections are available from McAllen, TX to Santiago de Queretaro each day?

Every day, the McAllen, TX to Santiago de Queretaro bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from McAllen, TX to Santiago de Queretaro take?

The fastest bus from McAllen, TX to Santiago de Queretaro is offered by Greyhound US and takes 17h 40m. Bus tickets for this connection cost $67. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from McAllen, TX to Santiago de Queretaro?

The earliest bus arriving in Santiago de Queretaro from McAllen, TX starts at 9:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from McAllen, TX to Santiago de Queretaro?

The latest bus trip departing from McAllen, TX for Santiago de Queretaro starts at 4:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the McAllen, TX Santiago de Queretaro route?

When traveling by bus from McAllen, TX to Santiago de Queretaro, passengers can travel with Greyhound US, FlixBus and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between McAllen, TX and Santiago de Queretaro?

You can check all the direct connections between McAllen, TX and Santiago de Queretaro by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US, FlixBus and Greyhound Lines Mexico.

What can I take with me on the McAllen, TX to Santiago de Queretaro bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the McAllen, TX Santiago de Queretaro bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the McAllen, TX Santiago de Queretaro bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from McAllen, TX to Santiago de Queretaro on your planned travel date.

Available seat classes which are offered on the bus route McAllen, TX to Santiago de Queretaro

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to McAllen, TX and to Santiago de Queretaro

Here’s an overview of the most popular bus routes to McAllen, TX and to Santiago de Queretaro. Simply click on the connection of your choice, and you will find all the details about your bus route!