Bus Louisville, KY to San Antonio, TX

Compare all timetables for the bus from Louisville, KY to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Louisville, KY to San Antonio, TX from various bus operators like Greyhound US for the next days.

today

tomorrow

$109

Tuesday

Wednesday

$116

Thursday

$116

Friday

Saturday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	46h 30m	10:55 PM	Louisville, KY	Greyhound Bus Station	8:25 PM	San Antonio, TX	Pearl District	Economy	$109	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/27/2026 10:55:00 PM to Pearl District, San Antonio, TX (USA) arriving at 7/29/2026 8:25:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 46h 30m
Greyhound US	26h 25m	3:35 AM	Louisville, KY	Greyhound Bus Station	5:00 AM	San Antonio, TX	Bus Station	Economy	$110	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/27/2026 3:35:00 AM to Bus Station, San Antonio, TX (USA) arriving at 7/28/2026 5:00:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 26h 25m
Greyhound US	26h 0m	10:55 PM	Louisville, KY	Greyhound Bus Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$110	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/27/2026 10:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/28/2026 11:55:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 26h 0m
Greyhound US	40h 35m	7:35 AM	Louisville, KY	Greyhound Bus Station	11:10 PM	San Antonio, TX	Pearl District	Economy	$110	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/27/2026 7:35:00 AM to Pearl District, San Antonio, TX (USA) arriving at 7/28/2026 11:10:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 40h 35m
Greyhound US	24h 40m	6:30 PM	Louisville, KY	Greyhound Bus Station	6:10 PM	San Antonio, TX	Bus Station	Economy	$121	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/27/2026 6:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/28/2026 6:10:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 24h 40m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 0m	1:55 PM	Louisville, KY	Greyhound Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$116	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/29/2026 1:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/30/2026 12:55:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 24h 0m
Greyhound US	26h 0m	10:55 PM	Louisville, KY	Greyhound Bus Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$116	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/29/2026 10:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/30/2026 11:55:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 26h 0m
Greyhound US	24h 40m	6:30 PM	Louisville, KY	Greyhound Bus Station	6:10 PM	San Antonio, TX	Bus Station	Economy	$118	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/29/2026 6:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/30/2026 6:10:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 24h 40m
Greyhound US	46h 30m	10:55 PM	Louisville, KY	Greyhound Bus Station	8:25 PM	San Antonio, TX	Pearl District	Economy	$118	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/29/2026 10:55:00 PM to Pearl District, San Antonio, TX (USA) arriving at 7/31/2026 8:25:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 46h 30m
Greyhound US	26h 25m	3:35 AM	Louisville, KY	Greyhound Bus Station	5:00 AM	San Antonio, TX	Bus Station	Economy	$119	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/29/2026 3:35:00 AM to Bus Station, San Antonio, TX (USA) arriving at 7/30/2026 5:00:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 26h 25m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	26h 25m	3:35 AM	Louisville, KY	Greyhound Bus Station	5:00 AM	San Antonio, TX	Bus Station	Economy	$116	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/30/2026 3:35:00 AM to Bus Station, San Antonio, TX (USA) arriving at 7/31/2026 5:00:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 26h 25m
Greyhound US	24h 0m	1:55 PM	Louisville, KY	Greyhound Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$116	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/30/2026 1:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/31/2026 12:55:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 24h 0m
Greyhound US	24h 40m	6:30 PM	Louisville, KY	Greyhound Bus Station	6:10 PM	San Antonio, TX	Bus Station	Economy	$116	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/30/2026 6:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/31/2026 6:10:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 24h 40m
Greyhound US	26h 0m	10:55 PM	Louisville, KY	Greyhound Bus Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$116	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/30/2026 10:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/31/2026 11:55:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 26h 0m
Greyhound US	37h 50m	7:35 AM	Louisville, KY	Greyhound Bus Station	8:25 PM	San Antonio, TX	Pearl District	Economy	$117	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/30/2026 7:35:00 AM to Pearl District, San Antonio, TX (USA) arriving at 7/31/2026 8:25:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 37h 50m

Best Price Offer: The price for the cheapest bus from Louisville, KY to San Antonio, TX is $97 on 8/12/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Louisville, KY and San Antonio, TX

See here how frequent the connections between Louisville, KY and San Antonio, TX are, during different times and days of the week.

Monday is the busiest day, with more than 6 daily buses from Louisville, KY to San Antonio, TX. Wednesday has instead the fewest connections, with only 5 daily coaches between Louisville, KY and San Antonio, TX.

The busiest time of the day is the Evening, with 9 buses from Louisville, KY to San Antonio, TX, while Morning sees the fewest connections between Louisville, KY and San Antonio, TX, with 2 offers.

Facts about the bus from Louisville, KY to San Antonio, TX

Compare all providers like Greyhound US that travel 5 times every day by bus from Louisville, KY to San Antonio, TX in one click! Book your bus ticket from Louisville, KY to San Antonio, TX starting from $97!

Cheapest Bus	$97
Fastest Bus	23h 0m
Earliest Bus	3:35 AM
Latest Bus	10:55 PM
Daily Bus Routes	5 Ø
Distance	949.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Louisville, KY to San Antonio, TX

Every day, 5 buses from 1 bus companies leave Louisville, KY for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

Monday 07/27

$109

Tuesday 07/28

Wednesday 07/29

$116

Thursday 07/30

$116

Friday 07/31

Saturday 08/01

Sunday 08/02

Monday 08/03

$123

Tuesday 08/04

$120

Wednesday 08/05

Thursday 08/06

$109

Friday 08/07

$113

Saturday 08/08

Sunday 08/09

Monday 08/10

Tuesday 08/11

Wednesday 08/12

$97

Thursday 08/13

Friday 08/14

Saturday 08/15

Sunday 08/16

Monday 08/17

Tuesday 08/18

Wednesday 08/19

Thursday 08/20

Friday 08/21

Saturday 08/22

The cheapest time to travel from Louisville, KY to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from Louisville, KY to San Antonio, TX, for the next 30 days.

With a price starting from $97, Wednesday is the cheapest day for a bus from Louisville, KY to San Antonio, TX. Monday instead is the most expensive day with prices starting from $109.

Night is the cheapest day time for bus tickets from Louisville, KY to San Antonio, TX, with $97. Afternoon is the most expensive time of the day with prices starting from $116.

How to save money travelling from Louisville, KY to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Louisville, KY to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Louisville, KY to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Louisville, KY to San Antonio, TX are also emptier.

All bus stations and stops in Louisville, KY and San Antonio, TX

In the map below, you can see where to find all bus stations in Louisville, KY and San Antonio, TX.

Greyhound Bus Station

W Muhammad Ali Blvd 720

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

International Airport

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Commerce & Bowie Bus Stop

W. Southcross & Buffalo Bus Stop

Service and Comfort on the bus from Louisville, KY to San Antonio, TX

Want to know which seat classes are available on the buses from Louisville, KY to San Antonio, TX? Or which bus companies serve the route Louisville, KY to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Louisville, KY to San Antonio, TX bus

How much does a Louisville, KY San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $97 and takes 45h 30m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Louisville, KY to San Antonio, TX?

This route is offered by 1 companies with a range of ticket prices between $97 and $128. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Louisville, KY to San Antonio, TX each day?

Every day, the Louisville, KY to San Antonio, TX bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Louisville, KY to San Antonio, TX take?

The fastest bus from Louisville, KY to San Antonio, TX is offered by Greyhound US and takes 23h 0m. Bus tickets for this connection cost $128. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Louisville, KY to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Louisville, KY starts at 3:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Louisville, KY to San Antonio, TX?

The latest bus trip departing from Louisville, KY for San Antonio, TX starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Louisville, KY San Antonio, TX route?

When traveling by bus from Louisville, KY to San Antonio, TX, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Louisville, KY and San Antonio, TX?

You can check all the direct connections between Louisville, KY and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Louisville, KY to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Louisville, KY San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Louisville, KY San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Louisville, KY to San Antonio, TX on your planned travel date.

Available seat classes which are offered on the bus route Louisville, KY to San Antonio, TX

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Louisville, KY and to San Antonio, TX

Here’s an overview of the most popular bus routes to Louisville, KY and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!