Which bus from Lewiston, ME to San Diego is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $221
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Compare all timetables for the bus from Lewiston, ME to San Diego

Here is a selection of the cheapest bus trips from the schedule from Lewiston, ME to San Diego from various bus operators like Greyhound US for the next days.

today
tomorrow
$221
Tuesday
Wednesday
$276
Thursday
Friday
$308
Saturday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 80h 40m 12:40 PM Lewiston, ME Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $221
Greyhound US 80h 35m 12:45 PM Lewiston, ME Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $221
  • Did you know that if you travel from Lewiston, ME to San Diego via Boston, MA, you can save more than $32? You can find the corresponding connections below.
    • Greyhound US
      102h 40m
      0
      12:45 PM
      Lewiston, ME
      Bus Stop
      4:15 PM
      Boston, MA
      Atlantic and Beach St
      0
      Greyhound US
      Economy
      $24
      • Waiting Time 20h 15m
    • Greyhound US
      78h 55m
      0
      12:30 PM
      Boston, MA
      South Station
      4:25 PM
      San Diego
      Old Town Transit Center
      0
      Greyhound US
      Economy
      $165
    Travel time is 25h 5m longer, but you will save $32

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 80h 40m 12:40 PM Lewiston, ME Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $276
Greyhound US 80h 35m 12:45 PM Lewiston, ME Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $276
  • Did you know that if you travel from Lewiston, ME to San Diego via Boston, MA, you can save more than $87? You can find the corresponding connections below.
    • Greyhound US
      102h 40m
      0
      12:45 PM
      Lewiston, ME
      Bus Stop
      4:15 PM
      Boston, MA
      Atlantic and Beach St
      0
      Greyhound US
      Economy
      $24
      • Waiting Time 20h 15m
    • Greyhound US
      78h 55m
      0
      12:30 PM
      Boston, MA
      South Station
      4:25 PM
      San Diego
      Old Town Transit Center
      0
      Greyhound US
      Economy
      $165
    Travel time is 25h 5m longer, but you will save $87

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 80h 40m 12:40 PM Lewiston, ME Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $308
Greyhound US 80h 35m 12:45 PM Lewiston, ME Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $308
  • Did you know that if you travel from Lewiston, ME to San Diego via Boston, MA, you can save more than $119? You can find the corresponding connections below.
    • Greyhound US
      102h 40m
      0
      12:45 PM
      Lewiston, ME
      Bus Stop
      4:15 PM
      Boston, MA
      Atlantic and Beach St
      0
      Greyhound US
      Economy
      $24
      • Waiting Time 20h 15m
    • Greyhound US
      78h 55m
      0
      12:30 PM
      Boston, MA
      South Station
      4:25 PM
      San Diego
      Old Town Transit Center
      0
      Greyhound US
      Economy
      $165
    Travel time is 25h 5m longer, but you will save $119

Best Price Offer: The price for the cheapest bus from Lewiston, ME to San Diego is $221 on 7/27/2026. Flexible travelers save on ticket prices.


Facts about the bus from Lewiston, ME to San Diego

Compare all providers like Greyhound US that travel 2 times every day by bus from Lewiston, ME to San Diego in one click! Book your bus ticket from Lewiston, ME to San Diego starting from $221!

Cheapest Bus $221
Fastest Bus 77h 35m
Earliest Bus 12:40 PM
Latest Bus 12:45 PM
Daily Bus Routes 2 Ø
Distance 2,621.9 miles
Bus Companies Greyhound US

Cheapest bus connections from Lewiston, ME to San Diego

Every day, 2 buses from 1 bus companies leave Lewiston, ME for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/26
Monday 07/27
$221
Tuesday 07/28
Wednesday 07/29
$276
Thursday 07/30
Friday 07/31
$308
Saturday 08/01
Sunday 08/02
$308
Monday 08/03
Tuesday 08/04
Wednesday 08/05
Thursday 08/06
$268
Friday 08/07
$296
Saturday 08/08
$309
Sunday 08/09
$265
Monday 08/10
$255
Tuesday 08/11
Wednesday 08/12
Thursday 08/13
Friday 08/14
Saturday 08/15
Sunday 08/16
$294
Monday 08/17
Tuesday 08/18
Wednesday 08/19
Thursday 08/20
Friday 08/21
Saturday 08/22

How to save money travelling from Lewiston, ME to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lewiston, ME to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lewiston, ME to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lewiston, ME to San Diego are also emptier.

All bus stations and stops in Lewiston, ME and San Diego

In the map below, you can see where to find all bus stations in Lewiston, ME and San Diego.

Service and Comfort on the bus from Lewiston, ME to San Diego

Want to know which seat classes are available on the buses from Lewiston, ME to San Diego? Or which bus companies serve the route Lewiston, ME to San Diego? Below you will find answers to your questions.

FAQs about the Lewiston, ME to San Diego bus

How much does a Lewiston, ME San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $221 and takes 77h 40m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Lewiston, ME to San Diego?

This route is offered by 1 companies with a range of ticket prices between $221 and $308. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Lewiston, ME to San Diego each day?

Every day, the Lewiston, ME to San Diego bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lewiston, ME to San Diego take?

The fastest bus from Lewiston, ME to San Diego is offered by Greyhound US and takes 77h 35m. Bus tickets for this connection cost $221. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lewiston, ME to San Diego?

The earliest bus arriving in San Diego from Lewiston, ME starts at 12:40 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lewiston, ME to San Diego?

The latest bus trip departing from Lewiston, ME for San Diego starts at 12:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lewiston, ME San Diego route?

When traveling by bus from Lewiston, ME to San Diego, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lewiston, ME and San Diego?

You can check all the direct connections between Lewiston, ME and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Lewiston, ME to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lewiston, ME San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lewiston, ME San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lewiston, ME to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Lewiston, ME to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lewiston, ME and to San Diego

Here’s an overview of the most popular bus routes to Lewiston, ME and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Lewiston, ME and to San Diego
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